Other Solvents
Medchemexpress LLC Yohimbine-13C,d3 | 1261254-59-4 | 99.0% | 1 MG
Yohimbine-13C,d3 is a 13C- and deuterium labeled version of Yohimbine, known as a potent and relatively nonselective alpha 2-adrenergic receptor (AR) antagonist with an IC50 of 0.6 μM. This stable isotope-labeled compound appears as a white to off-white solid and is ideal for use as a tracer or internal standard in quantitative analytical methods such as NMR, GC-MS, or LC-MS. It boasts a high purity of 99.0%. For optimal stability, store as a powder at -20°C for up to 3 years or 4°C for 2 years, or in solvent at -80°C for 6 months or -20°C for 1 month.
- Stable isotope-labeled compound
- Potent alpha 2-adrenergic receptor antagonist
- Suitable for use as a tracer
- Functions as an internal standard for quantitative analysis
- Compatible with NMR, GC-MS, and LC-MS methods
- Appears as a white to off-white solid
- Purity of 99.0%
- Specific storage conditions for powder and solvent forms
Medchemexpress LLC Fenofibric acid-d6 | 1092484-69-9 | 99.6% | 5 MG
Fenofibric acid-d6 (FNF acid-d6) is the deuterium-labeled form of Fenofibric acid. Fenofibric acid, an active metabolite of fenofibrate, acts as a PPAR activator with EC50s of 22.4 μM for PPARα, 1.47 μM for PPARγ, and 1.06 μM for PPARδ. It also inhibits COX-2 enzyme activity with an IC50 of 48 nM. Deuterium substitution in drug molecules is of interest due to its potential impact on pharmacokinetic and metabolic profiles.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- For research use only.
Medchemexpress LLC Phenacetin-d5 | 69323-74-6 | 99.5% | 1 ML
Phenacetin-d5 is the deuterium labeled version of Phenacetin. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent, a selective COX-3 inhibitor, and is used as a probe for cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Sigma Aldrich Fine Chemicals Biosciences Ethylene glycol bis2 amino500G
Ethylene glycol bis2 amino500G
Medchemexpress LLC Sucrose-d14 (D-(+)-Saccharose-d14) | 57-50-1 | 99.0% | 1 MG
Sucrose-d14 is the deuterium labeled Sucrose, a disaccharide composed of two monosaccharides, glucose and fructose. It can be applied in animal models for metabolic disease, obesity, and diet preference. This product serves as a valuable tool for quantitative analysis in various research applications.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium substitution can affect the pharmacokinetic and metabolic profiles of drugs.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
eMolecules 2679-87-0 | Sec-butyl ethyl ether | Combi-Blocks | MFCD00053773 | 102.177 | C6H14O | 97.000 | CCOC(C)CC | 5g | 267198083
Sec-butyl ethyl ether | Combi-Blocks | 2679-87-0 | MFCD00053773 | 102.177 | C6H14O | 97.000 | CCOC(C)CC | 5g | 267198083
![Medchemexpress LLC 3H-imidazo[4,5-f]quinoxalin-2-amine, 8-methyl-3-(methyl-d3) | 122457-31-2 | MFCD00210329 | 99.0% | 216.26 g/mol | C11H8D3N5 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000285110.png-250.jpg)
Medchemexpress LLC 3H-imidazo[4,5-f]quinoxalin-2-amine, 8-methyl-3-(methyl-d3) | 122457-31-2 | MFCD00210329 | 99.0% | 216.26 g/mol | C11H8D3N5 | 5 MG
MeIQx-d3 is the triply deuterated isotopologue of MeIQx supplied as a high-purity analytical standard for use as an internal standard and tracer in mass spectrometry and quantitative exposure studies.
- Triply deuterated isotopologue for use as an internal standard.
- High purity: 99.0%.
- Molecular formula C11H8D3N5; molecular weight 216.26 g/mol.
- Available as a 5 MG powder package.
- Storage: powder -20°C; in solvent -80°C for 6 months or -20°C for 1 month.
- Applications include LC-MS/MS quantitation, tracer studies, and method development.
Medchemexpress LLC Choline-d9 chloride | 61037-86-3 | 99.9% | 50 MG
Choline-d9 (chloride) is the deuterium-labeled form of choline chloride, an organic compound. It functions as a quaternary ammonium salt, an acyl group acceptor, and a choline acetyltransferase substrate. Choline chloride is also utilized as an important feed additive, particularly for chickens, where it promotes growth.
- Used as a tracer.
- Suitable as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can influence the pharmacokinetic and metabolic profiles of pharmaceuticals.
Medchemexpress LLC Metronidazole-d3 | 83413-09-6 | MFCD27702816 | 100.0% | 1 MG
Metronidazole-d3 is a deuterium-labeled form of Metronidazole. It can be used for research purposes, including as a tracer or an internal standard for quantitative analysis by techniques like NMR, GC-MS, or LC-MS. This compound typically appears as a light yellow to yellow solid.
- Can be used as a tracer.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Contains stable heavy isotopes incorporated into drug molecules.
- Deuteration offers potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Sulfamethoxazole-d4 | 1020719-86-1 | 99.3% | 1 ML
Sulfamethoxazole-d4 is a deuterium-labeled sulfonamide antibiotic, also known as Ro 4-2130-d4. It demonstrates widespread antibacterial activity by inhibiting bacterial folate metabolism, specifically by competing with 4-Aminobenzoic acid (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. This product is intended for research use only.
- Deuterium labeled analog
- Sulfonamide antibiotic with widespread antibacterial activity
- Inhibits bacterial folate metabolism
- Suitable for studying urinary tract infections (UTIs), prostatitis, and bronchitis
- Supplied as a 10 mM solution in DMSO
Medchemexpress LLC Enalapril-d5 (maleate) | 349554-02-5 | M001579 | 99.0% | 5 MG
Enalapril-d5 maleate is a deuterium-labeled form of Enalapril, a potent and long-acting angiotensin-converting enzyme (ACE) inhibitor.
- Used for treating hypertension, congestive heart failure, and diabetic nephropathy.
- Inhibits the conversion of angiotensin I to angiotensin II.
- Results in decreased vasoconstriction and reduced aldosterone secretion.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Adenosine-d13 | 58-61-7 | 96.6% | 1 MG
Adenosine-d13 is a deuterium-labeled version of Adenosine, a widely present endogenous autacoid. It functions by activating four G protein-coupled receptors (A1, A2A, A2B, and A3), influencing various cellular physiological processes including neuronal activity, vascular function, platelet aggregation, and blood cell regulation. This compound is intended for research use only.
- Can be used as a tracer or internal standard for quantitative analysis.
- Suitable for techniques like NMR, GC-MS, or LC-MS.
- Incorporation of stable heavy isotopes, such as deuterium, into drug molecules may impact pharmacokinetic and metabolic profiles.
Sigma Aldrich Fine Chemicals Biosciences Urea-13C,15N2 99 atom % 13C, 98 atom % 15N | 58069-83-3 | MFCD00145506 | 500MG
Urea-13C,15N2 99 atom % 13C, 98 atom % 15N | Purity: 99% (CP) | Mol Wt: 63.03 | 58069-83-3 | MFCD00145506 | 500MG
Medchemexpress LLC Amlodipine-d4 maleate | 2714486-25-4 | 98.2% | 1 MG
Amlodipine-d4 maleate | 2714486-25-4 | 98.2% | 1 MG
Medchemexpress LLC Levofloxacin-d8 | 1217716-71-6 | 99.8% | 5 MG
Levofloxacin-d8 is the deuterium-labeled version of Levofloxacin. Levofloxacin is a synthetic fluoroquinolone and an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, thereby halting DNA replication. It is intended for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS