Diterpenoids
Cayman Chemical 7-acetyl PaclItaxel 1mg
An inhibitor of microtubule depolymerization; inhibits calcium-induced microtubule depolymerization at 10 µM; reduces the growth of J774.2 macrophages (IC50 = ~60 nM)
Sigma Aldrich Fine Chemicals Biosciences Pristane | 1921-70-6 | MFCD00008952 | 100ml
Pristane | 98% | MW: 268.52 | 1921-70-6 | MFCD00008952 | 100ml
Medchemexpress LLC Teprenone | 3796-63-2 | >99.8% | 50 MG
Teprenone, also known as (5E,9E,13E)-Geranylgeranylacetone, is an isomer with antiulcer activity. It induces transcriptional activation of HSP genes, which may enhance gastric mucosal defense under stress conditions. This product is for research use only.
- Isomer with antiulcer activity
- Induces transcriptional activation of HSP genes
- May increase gastric mucosal defense at conditions of stress
- For research use only
eMolecules 568-72-9 | Tanshinone IIA | MFCD00238692 | 100mg
Ambeed | Tanshinone IIA | 100mg | 552521161 | A104838 | 568-72-9 | MFCD00238692 | 294.350 | C19H18O3
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Selleck Chemical LLC Nab-Paclitaxel-E1068-100MG
Nab-Paclitaxel is a novel solvent-free paclitaxel in which the binding ratio of paclitaxel to human albumin is approximately 1 9 It is an anti-microtubule drug that promotes microtubule aggregation in tubulin dimers and inhibits microtubule depolymerization to stabilize the microtubule system Solutions are unstable and should be fresh-prepared
Medchemexpress LLC 10-Oxo Docetaxel (Docetaxel Impurity 1) | 167074-97-7 | 93.9% | 805.86 | 5 MG
10-Oxo Docetaxel (Docetaxel Impurity 1) is a novel taxoid having remarkable anti-tumor properties and is a Docetaxel intermediate. It is for research use only and not sold to patients.
- Novel taxoid
- Remarkable anti-tumor properties
- Docetaxel intermediate
- For research use only
Medchemexpress LLC Topoisomerase IIα-in-8 | 1251578-67-2 | 314.32 | C15H15FN6O | 1 MG
Topoisomerase IIα-IN-8 is a research-grade small-molecule inhibitor of human DNA topoisomerase IIα reported as a weak inhibitor (IC50 = 462 ± 38.0 μM). It is supplied as a powder for laboratory use, has molecular formula C15H15FN6O and molecular weight 314.32 g·mol-1, and is provided with downloadable product and safety documentation. For research use only.
- Weak inhibitor of human DNA topoisomerase IIα (IC50 = 462 ± 38.0 μM).
- Shows limited antiproliferative activity (GI50 > 100 μM in HEK293 and HT-29 cells).
- Supplied as a powder with specified storage recommendations for powder and solutions.
- Molecular formula C15H15FN6O; molecular weight 314.32 g·mol-1.
- Datasheet and safety data sheet available for handling and purity details.
Medchemexpress LLC Paclitaxel-d5 | 1129540-33-5 | 99.9% | C47H46D5NO14 | 5 MG
Paclitaxel-d5 is a deuterium-labeled Paclitaxel, a naturally occurring antineoplastic agent that stabilizes tubulin polymerization. This compound is suitable for research applications.
- Can be used as a tracer
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration can impact pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Paclitaxel-d5 | 1129540-33-5 | 99.9% | C47H46D5NO14 | 500 UG
Paclitaxel-d5 is a deuterium-labeled Paclitaxel, a naturally occurring antineoplastic agent that stabilizes tubulin polymerization. Deuteration has garnered attention due to its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes of hydrogen, carbon, and other elements into drug molecules as tracers for quantitation during the drug development process.
AG Scientific Inc Aphidicolin, 1 MG
Aphidicolin is a reversible inhibitor of nuclear DNA replication in eukaryotes and some animal viruses. It interferes with dCTP-specific binding sites on DNA polymerase-alpha. It also works on other DNA polymerases, however it does not work on DNA polymerase-alpha. Viruses inducing DNA polymerase-alpha, such as Herpes simplex, can be affected by aphidicolin because of its mechanism. It could be used for clinical study. Isolated from Nigrospora oryzae.CAS Number: 38966-21-1Molecular Weight: 338.5Chemical Formula: C20H34O4Solubility: Methanol: Clear colorless solution at 10 mg/mlStorage Temperature: 2-8CResearch or further manufacturing use only, not for food or drug use.
Medchemexpress LLC Phytol (Standard) | 150-86-7 | 100 MG
Phytol (Standard) is an analytical standard of Phytol, derived from chlorophyll, and is suitable for research and analytical applications. This orally active diterpenoid alcohol exhibits antioxidant, anti-inflammatory, anti-schistosomiasis, and antibacterial properties.
- Analytical standard for qualitative, quantitative, and methodological research
- Used in HPLC, GC, and MS experiments
- Possesses antioxidant, anti-inflammatory, anti-schistosomiasis, and antibacterial activities
Apexbio Technology LLC Tanshinone IIA 568-72-9 10mM (in 1mL DMSO)
Tanshinone IIA (CAS 568-72-9) is a diterpene quinone extracted from the medicinal plant Salvia miltiorrhiza (Danshen) It modulates cellular signaling by inhibiting the binding of transcription factors NF- B and AP-1 to DNA thereby regulating gene expression associated with inflammation and proliferation Tanshinone IIA has demonstrated the capacity to suppress -amyloid aggregation and protect neuronal PC12 cells against -amyloid-induced apoptosis It exhibits both antioxidant and anti-inflammatory properties supporting its use in studies related to oncology neurodegeneration and inflammation
Medchemexpress LLC Paclitaxel-d5 (benzoyloxy) | 1261254-56-1 | 98.1% | C47H46D5NO14 | 500 UG
Paclitaxel-d5 (benzoyloxy) is the deuterium-labeled Paclitaxel. Paclitaxel is a naturally occurring antineoplastic agent that stabilizes tubulin polymerization. It can cause both mitotic arrest and apoptotic cell death and also induces autophagy. This product is for research use only and not sold to patients.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Paclitaxel | 5 MG
Paclitaxel is a naturally occurring antineoplastic agent that stabilizes tubulin polymerization. It can cause both mitotic arrest and apoptotic cell death, and it also induces autophagy.
- Naturally occurring antineoplastic agent
- Stabilizes tubulin polymerization
- Causes mitotic arrest
- Causes apoptotic cell death
- Induces autophagy