Diterpenoids
Apexbio Technology LLC Resiniferatoxin 1mg
Resiniferatoxin (CAS 57444-62-9) is a potent selective agonist of the transient receptor potential vanilloid 1 (TRPV1) channel derived from plant sources By activating TRPV1 it induces sustained calcium influx in TRPV1-expressing sensory neurons leading to their desensitization or ablation In animal studies resiniferatoxin has been shown to induce long-lasting elimination of TRPV1-positive primary sensory afferents and blunt associated neural reflexes including those mediating cardiac sympathetic input Resiniferatoxin is widely used in research to investigate pain pathways sensory neuron function and neurogenic inflammation
TARGETMOL CHEMICALS INC Tanshinone I 25MG
Also available in 5 mg, 10 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Tanshinone I (Tanshinone A), an active principle isolated from the herbal medicine Salvia miltiorrhiza, displays cytotoxicity against tumor cells. Purity 98.58%
Medchemexpress LLC Docetaxel | 114977-28-5 | 99.9% | C43H53NO14 | 1 ML
Docetaxel is a microtubule depolymerization inhibitor with an IC50 of 0.2 μM. It attenuates the effects of bcl-2 and bcl-xL gene expression, leading to cell cycle arrest at G2/M and subsequent apoptosis. This compound demonstrates anti-cancer activity.
- Microtubule depolymerization inhibitor
- Attenuates effects of bcl-2 and bcl-xL gene expression
- Arrests cell cycle at G2/M
- Leads to cell apoptosis
- Demonstrates anti-cancer activity
eMolecules 568-73-0 | Tanshinone i | MFCD00210563 | 1g
Combi-Blocks, Inc. | Tanshinone i | 1g | 603145422 | QC-9410 | 95.000 | 568-73-0 | MFCD00210563 | 276.291 | C18H12O3
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Selleck Chemical LLC Phytol S5121-25mg
Phytol (Trans-Phytol) a diterpene alcohol from chlorophyll widely used as a food additive and in medicinal fields shows antinociceptive and antioxidant activities as well as anti-inflammatory and antiallergic effects It is a specific activator of PPAR
Selleck Chemical LLC Paclitaxel S1150-1g
Paclitaxel is a microtubule polymer stabilizer with IC50 of 0 1 pM in human endothelial cells Paclitaxel can cause both mitotic arrest and apoptotic cell death Paclitaxel also induces autophagy
Selleck Chemical LLC Docetaxel S1148-1g
Docetaxel an analog of paclitaxel is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules
AdipoGen (+)-Aphidicolin,Chemical. CAS: 38966-21-1
(+)-Aphidicolin, AdipoGen Life Sciences. Chemical. CAS: 38966-21-1. Formula: C20H34O4. MW: 338.5. Isolated from Phoma sp. BS 7210. Phytotoxin. Antibiotic. Antiviral and antineoplastic agent. Antileishmanial agent. Reversible inhibitor of eukaryotic nuclear DNA replication. Useful for cell synchronization. Blocks the cell cycle at G1/S phase. Prolongs the half life of DNA methyltransferase. DNA methylation/demethylation modulator. Specific DNA polymerase alpha and delta inhibitor in eukaryotic cells and in some viruses of animal origin. Acts synergistically with vincristine and doxorubicin. Apoptosis inhibitor/inducer.
TARGETMOL CHEMICALS INC Paclitaxel 500MG
Also available in 1 g, 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest, apoptosis, and cell autophagy. Purity 99.92%
Cayman Chemical Docetaxel-d9 1mg
An internal standard for the quantification of docetaxel by GC- or LC-MS
Cayman Chemical Paclitaxel Neurochemicals
A potent disruptor of microtubules used as a chemotherapeutic compound; inhibits growth of cervical (HeLa), lung (A549), breast (MCF-7), colon (HT-29), ovarian (OVG-1), and pancreatic (PC-Sh) carcinomas with IC50 values ranging from 2.5-7.5 nM; induces mitotic arrest and initiates apoptosis of cancer cells through multiple mechanisms
Cayman Chemical -AphIdIcolIn 1mg
A natural tetracyclic diterpene with antiviral activity against herpes simplex; a cell-permeable, reversible inhibitor of DNA replication in eukaryotic cells, specifically blocking the activity of DNA polymerases α, δ, and ε when used at low micromolar levels.
