Diterpenoids
Medchemexpress LLC Docetaxel (standard) | 114977-28-5 | 99.9% | C43H53NO14 | 100 MG
Docetaxel (standard) is an analytical standard of Docetaxel, developed for research and analytical applications. It functions as a microtubule depolymerization inhibitor and attenuates the effects of bcl-2 and bcl-xL gene expression. This compound arrests the cell cycle at G2/M and induces cell apoptosis, demonstrating anti-cancer activity.
- Acts as a microtubule depolymerization inhibitor
- Attenuates bcl-2 and bcl-xL gene expression
- Arrests cell cycle at G2/M
- Induces cell apoptosis
- Utilized in qualitative, quantitative, and methodological research experiments (e.g., HPLC, GC, MS)
- Appears as a white to off-white solid
Medchemexpress LLC 7-epi-docetaxel | 153381-68-1 | MFCD15071206 | 98.8% | 807.88 g·mol⁻¹ | C43H53NO14 | 10 MG
7-Epi-docetaxel is an epimeric impurity of docetaxel used as a research compound and microtubule/tubulin inhibitor. Supplied as a solid powder in a 10 mg quantity, it is intended for laboratory research use only and not for human or clinical applications.
- Impurity/epimer of docetaxel used to study tubulin dynamics and cytotoxicity.
- Solid powder formulation suitable for analytical and cell-based research.
- CAS number 153381-68-1 for unambiguous identification.
- Chemical formula C43H53NO14; molecular weight 807.88 g·mol⁻¹.
- High purity (98.8% reported by supplier) for analytical consistency.
- Store powder at -20°C for long term; store solutions at -80°C for long term per handling instructions.
Abcam Myricetin, irreversible Tr x R inhibitor, 5MG
MW 318.24 g/mol, Purity >97%. Directly inhibits MEK, JAK1, Akt and MKK4 kinase activity. Able to inhibit cytochrome P450 3A4 and 2C9 (IC₅₀ = 7.81 and 13.5 μM, respectively). .
The product is subject to the following: Abcam Restricted Use Statement
Abcam Myricetin, irreversible Tr x R inhibitor, 25MG
MW 318.24 g/mol, Purity >97%. Directly inhibits MEK, JAK1, Akt and MKK4 kinase activity. Able to inhibit cytochrome P450 3A4 and 2C9 (IC₅₀ = 7.81 and 13.5 μM, respectively). .
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Paclitaxel-d5 | 1129540-33-5 | 99.9% | C47H46D5NO14 | 5 MG
Paclitaxel-d5 is a deuterium-labeled Paclitaxel, a naturally occurring antineoplastic agent that stabilizes tubulin polymerization. This compound is suitable for research applications.
- Can be used as a tracer
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration can impact pharmacokinetic and metabolic profiles of drugs
Selleck Chemical LLC Docetaxel S1148-1g
Docetaxel an analog of paclitaxel is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules
Selleck Chemical LLC 10-deacetyl-paclitaxel S3933-5mg
10-deacetyl-paclitaxel (10-DAT Deacetyl Paclitaxel) is a semi-synthetic precursor of Paclitaxel
Selleck Chemical LLC Docetaxel S1148-250mg
Docetaxel an analog of paclitaxel is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules
Medchemexpress LLC Resiniferatoxin | 57444-62-9 | 25 MG
Resiniferatoxin, also known as (+)-Resiniferatoxin, is a selective agonist of the transient receptor potential vanilloid 1 (TRPV1) receptor. Isolated from the *Euphorbia resinifera* plant, this compound eliminates TRPV1+ primary sensory afferents and can blunt cardiac sympathetic afferent reflex for an extended period. This product is intended for research use only.
- Selective agonist for the TRPV1 receptor
- Isolated from the *Euphorbia resinifera* plant
- Eliminates TRPV1+ primary sensory afferents
- Blunts cardiac sympathetic afferent reflex