Diterpenoids
Enzo Life Sciences Docetaxel (5 mg). CAS: 114977-28-5
Docetaxel is taxane-type antineoplastic agent structurally similar to taxol. It reversibly binds to polymerized tubulin inhibiting depolymerization. It induces apoptosis in a large number of tumor cells and is a clinically important anticancer agent. Alternative name: Taxotere. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (25mg/ml) or 100% ethanol (25mg/ml). Long Term Storage: -20°C.
Medchemexpress LLC Isophytol (isovegetable alcohol) | 505-32-8 | MFCD00048380 | 99.7% | 296.53 | C20H40O | 100 G
Isophytol (isovegetable alcohol) is a branched-chain diterpenoid alcohol provided for research use as a biochemical assay reagent. It is a clear, oily organic compound (C20H40O, MW 296.53) commonly used in biochemical and analytical applications; manufacturer-stated purity is approximately 99.7%.
- Biochemical assay reagent for life-science research.
- High nominal purity suitable for analytical applications.
- Clear, oily liquid form for easy formulation and handling.
- Supplied in multiple pack sizes for laboratory convenience.
Cayman Chemical -AphIdIcolIn 1mg
A natural tetracyclic diterpene with antiviral activity against herpes simplex; a cell-permeable, reversible inhibitor of DNA replication in eukaryotic cells, specifically blocking the activity of DNA polymerases α, δ, and ε when used at low micromolar levels.
Cayman Chemical 10-acetyl Docetaxel 50mg
A derivative of paclitaxel and an inhibitor of microtubule depolymerization; inhibits calcium-induced depolymerization of calf brain MTP in a cell-free assay at 20 µM; cytotoxic to J774.2 cells (EC50 = 0.05 µM)
Medchemexpress LLC Nab-Paclitaxel 25mg | 25mg
Nab-Paclitaxel (Nanoparticle albumin-bound Paclitaxel) is an albumin-bound nanoparticle formulation of Paclitaxel (HY-B0015) Nab-Paclitaxel is composed of albumin and the active pharmaceutical ingredient Paclitaxel in which human albumin is used as an excipient to disperse and stabilize particles and carry the main drug Nab-Paclitaxel is a solvent-free taxane with higher response rates and improved tolerability Nab-Paclitaxel displays less toxicity and greater antitumor activity Nab-Paclitaxel is more readily available for tumor cell uptake in three rhabdomyosarcoma seven neuroblastoma cell lines and one ostersarcoma cell line Nab-Paclitaxel can be studied in cancer research for example breast cancer and solid tumors (The product specifications below only indicate the effective content of Paditaxel the actual albumin quality depends on the batch the ratio of each ingredient in this product is Paditaxel albumin -1 7 1 11)[1][2]
Medchemexpress LLC HY-N0866 5mg Medchemexpress, 20-Deoxyingenol CAS:54706-99-9 Purity:>98%
Medchemexpress, HY-N0866 5mg 20-Deoxyingenol CAS:54706-99-9 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical Paclitaxel Neurochemicals
A potent disruptor of microtubules used as a chemotherapeutic compound; inhibits growth of cervical (HeLa), lung (A549), breast (MCF-7), colon (HT-29), ovarian (OVG-1), and pancreatic (PC-Sh) carcinomas with IC50 values ranging from 2.5-7.5 nM; induces mitotic arrest and initiates apoptosis of cancer cells through multiple mechanisms
Apexbio Technology LLC Paclitaxel (Taxol) 33069-62-4 10mM (in 1mL DMSO)
Paclitaxel (Taxol) is a diterpenoid alkaloid initially isolated from the bark of Taxus brevifolia It exhibits antitumor activity primarily by disrupting microtubule dynamics Mechanistically paclitaxel binds tubulin and promotes microtubule polymerization thus stabilizing microtubules and inhibiting their depolymerization This mechanism impairs normal mitotic spindle formation arrests cells in G2-M phase of the cell cycle and induces apoptotic cell death Paclitaxel is extensively employed in biomedical research for investigating antineoplastic mechanisms and testing therapeutic interventions targeting various cancers such as ovarian breast head and neck and lung carcinoma