Diterpenoids
Apexbio Technology LLC Tanshinone IIA 568-72-9 10mM (in 1mL DMSO)
Tanshinone IIA (CAS 568-72-9) is a diterpene quinone extracted from the medicinal plant Salvia miltiorrhiza (Danshen) It modulates cellular signaling by inhibiting the binding of transcription factors NF- B and AP-1 to DNA thereby regulating gene expression associated with inflammation and proliferation Tanshinone IIA has demonstrated the capacity to suppress -amyloid aggregation and protect neuronal PC12 cells against -amyloid-induced apoptosis It exhibits both antioxidant and anti-inflammatory properties supporting its use in studies related to oncology neurodegeneration and inflammation
Apexbio Technology LLC Tanshinone IIA 568-72-9 20mg
Tanshinone IIA (CAS 568-72-9) is a diterpene quinone extracted from the medicinal plant Salvia miltiorrhiza (Danshen) It modulates cellular signaling by inhibiting the binding of transcription factors NF- B and AP-1 to DNA thereby regulating gene expression associated with inflammation and proliferation Tanshinone IIA has demonstrated the capacity to suppress -amyloid aggregation and protect neuronal PC12 cells against -amyloid-induced apoptosis It exhibits both antioxidant and anti-inflammatory properties supporting its use in studies related to oncology neurodegeneration and inflammation
Selleck Chemical LLC Docetaxel S1148-250mg
Docetaxel an analog of paclitaxel is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules
Medchemexpress LLC HY-N0360 10mg Medchemexpress, Dihydrotanshinone I CAS:87205-99-0 Purity:>98%
Medchemexpress, HY-N0360 10mg Dihydrotanshinone I CAS:87205-99-0 Dihydrotanshinone I is a natural compound extracted from Salvia miltiorrhiza Bunge which has been widely used for treating cardiovascular diseases. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC LDN-57444
LDN-57444 is a reversible competitive proteasome inhibitor for Uch-L1 with IC50 of 0 88 M 28-fold selectivity over isoform Uch-L3
AG Scientific Inc Aphidicolin, 1 MG
Aphidicolin is a reversible inhibitor of nuclear DNA replication in eukaryotes and some animal viruses. It interferes with dCTP-specific binding sites on DNA polymerase-alpha. It also works on other DNA polymerases, however it does not work on DNA polymerase-alpha. Viruses inducing DNA polymerase-alpha, such as Herpes simplex, can be affected by aphidicolin because of its mechanism. It could be used for clinical study. Isolated from Nigrospora oryzae.CAS Number: 38966-21-1Molecular Weight: 338.5Chemical Formula: C20H34O4Solubility: Methanol: Clear colorless solution at 10 mg/mlStorage Temperature: 2-8CResearch or further manufacturing use only, not for food or drug use.
Selleck Chemical LLC Paclitaxel S1150-1g
Paclitaxel is a microtubule polymer stabilizer with IC50 of 0 1 pM in human endothelial cells Paclitaxel can cause both mitotic arrest and apoptotic cell death Paclitaxel also induces autophagy
Medchemexpress LLC HY-N0134 5mg Medchemexpress, Tanshinone I CAS:568-73-0 Purity:>98%
Medchemexpress, HY-N0134 5mg Tanshinone I CAS:568-73-0 Tanshinone I is an inhibitor of type IIA human recombinant sPLA 2 ( IC 50 =11 μM) and rabbit recombinant cPLA 2 ( IC 50 =82 μM). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC TANSHINONE IIA, 50 MG
MedChemExpress LLC| Tanshinone IIA | 50 mg | HY-N0135 | Purity 99.74% | 568-72-9 | MW: 294.34
Apexbio Technology LLC Cryptotanshinone 35825-57-1 20mg
Cryptotanshinone (CAS 35825-57-1) is a bioactive diterpene quinone derived from Salvia miltiorrhiza It modulates cellular signaling pathways by interacting with various molecular targets including components of the STAT3 signaling cascade thereby influencing transcriptional activity Studies indicate that cryptotanshinone alters gene expression profiles associated with cellular stress responses and apoptosis Due to its ability to regulate molecular pathways relevant to cancer biology and oxidative stress cryptotanshinone is widely utilized in biomedical research investigating mechanisms of tumor progression chemoprevention and cytoprotection