Formic Acid
Formic acid (HCOOH) is naturally-occurring, flammable, corrosive, organic, and the simplest carboxylic acid. Used as a hydride ion source in synthetic organic chemistry, a mobile phase component in HPLC, a preservative/antibacterial agent in agriculture, etc.
Formic or methanoic acid (CAS: 64-18-6; PubChem ID: 284) is a colorless organic acid with the formula HCOOH. At ambient temperatures, it has a strong, penetrating odor, like acetic acid. Used in chemical synthesis as an intermediate, this simple carboxylic acid is miscible in water and most organic solvents and is somewhat hydrocarbon-soluble.
Formic acid occurs naturally in the venom of some ants and bees. Formate, the conjugate base of formic acid, also occurs naturally in bodily fluids following methanol poisoning.
Formic acid is a source of hydride ion in synthetic organic chemistry, as in the Eschweiler-Clarke and Leuckart-Wallach reactions. It is also a useful component of the mobile phase in reversed-phase high-performance liquid chromatography (RP-HPLC) for peptides, proteins, and intact viruses.
Although formic acid is easily metabolized and eliminated, it can have toxic effects. Methanol metabolism produces formic acid and formaldehyde, which are responsible for the optic nerve damage that results from methanol poisoning. Chronic exposure in humans may cause kidney damage and skin allergies in some people.
In diluted forms, formic acid and formate esters are used as artificial flavorings and perfume additives. In higher concentrations, formic acid is flammable, and skin and eye contact with concentrated liquid or vapors is dangerous.
In agriculture, formic acid is used as a preservative and antibacterial agent and by beekeepers to kill mites. It is useful in leather tanning, textile dyeing and finishing, and in rubber production. Formic acid replaces mineral acids in limescale removers and other cleaning products.
Water with 0.1% Formic Acid, LabReady™ Solvent Blend, for LC-MS and HPLC, Solstice
CAS: 7732-18-5 Synonym: water,dihydrogen oxide,distilled water,purified water,water vapor,sterile water,water, purified,water, deionized,water, mineral,dihydrogen monoxide
Acetonitrile with 0.1% Formic Acid, LabReady™ Solvent Blend, for LC-MS and HPLC, Solstice
CAS: 75-05-8 Molecular Formula: C2H3N Molecular Weight (g/mol): 41.053 InChI Key: WEVYAHXRMPXWCK-UHFFFAOYSA-N Synonym: methyl cyanide,cyanomethane,ethanenitrile,methanecarbonitrile,ethyl nitrile,methane, cyano,acetonitrile,cyanure de methyl,methylkyanid,mecn PubChem CID: 6342 ChEBI: CHEBI:38472 IUPAC Name: acetonitrile SMILES: CC#N
Water with 0.1% Formic acid, LabReady™ Solvent Blend, Solstice
CAS: 7732-18-5 Synonym: water,dihydrogen oxide,distilled water,purified water,water vapor,sterile water,water, purified,water, deionized,water, mineral,dihydrogen monoxide
Acetonitrile with 0.1% Formic acid, LabReady™ Solvent Blend, Solstice
CAS: 75-05-8 Molecular Formula: C2H3N Molecular Weight (g/mol): 41.053 InChI Key: WEVYAHXRMPXWCK-UHFFFAOYSA-N Synonym: methyl cyanide,cyanomethane,ethanenitrile,methanecarbonitrile,ethyl nitrile,methane, cyano,acetonitrile,cyanure de methyl,methylkyanid,mecn PubChem CID: 6342 ChEBI: CHEBI:38472 IUPAC Name: acetonitrile SMILES: CC#N
Formic Acid : Triethylamine 1:1 Solution, Solstice
CAS: 585-29-5 Molecular Formula: C7H17NO2 Molecular Weight (g/mol): 147.218 MDL Number: MFCD00134943 InChI Key: PTMFUWGXPRYYMC-UHFFFAOYSA-N Synonym: unii-un4t038p8m,triethylamine formate,teaf,triethylammonium formate,triethylamine, formate,triethylammonium formate mi,triethylammoniumformate,triethylammonium format,hcooh et3n,formic acid triethylamine PubChem CID: 11084032 IUPAC Name: N,N-diethylethanamine;formic acid SMILES: CCN(CC)CC.C(=O)O
Formic Acid Solution, Solstice
CAS: 64-18-6 Molecular Formula: CH2O2 Molecular Weight (g/mol): 46.025 MDL Number: MFCD00003297 InChI Key: BDAGIHXWWSANSR-UHFFFAOYSA-N Synonym: methanoic acid,formylic acid,aminic acid,bilorin,hydrogen carboxylic acid,formisoton,myrmicyl,formira,acide formique,collo-bueglatt PubChem CID: 284 ChEBI: CHEBI:30751 IUPAC Name: formic acid SMILES: C(=O)O
LAB ALLEY Formic Acid 99% LC/MS Grade
Formic Acid is the simplest carboxylic acid containing only one carbon. It is a colorless liquid with a pungent aroma. It is about 10 times stronger than Acetic Acid. The high acidity level and reducing nature of this compound makes it different from other carboxylic acids. LC/MS is a versatile technique that combines the physical separation property of Liquid Chromatography with the mass analysis property of Mass Spectroscopy. LC-MS Grade Formic Acid is high-purity solvent for preparing elution solvents for HPLC separations of protein and peptides. LC/MS Grade Formic Acid is well suited as a chromatography additive for use in LCMS and HPLC applications.
Proteochem Inc Formic Acid Ampules 10X1Ml (10/Pk)
Proteomics Grade Formic Acid Ampules 10 x 1.0 mL (CAS 64-18-6) recommended as an HPLC and LCMS mobile phase additive. Each Formic Acid ampule contains 1.0 mL of Proteomics Grade Formic Acid.
Sigma Aldrich Fine Chemicals Biosciences SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES
NC3982132 FORMIC ACID 98-100 FOR HPLC L
Medchemexpress LLC GZD856 formic | 2804039-78-7 | 95.4% | 578.58 g/mol | C30H29F3N6O3 | 1 ML
GZD856 formic is a research-grade small-molecule inhibitor supplied as a 10 mM solution in DMSO for laboratory use. It is provided as the formic salt in a 1 mL vial and is intended for in vitro and exploratory studies needing a pre-dissolved, characterized compound.
- Pre-formulated 10 mM solution for immediate use.
- Supplied in a 1 mL vial for small-scale experiments.
- Formic salt form to enhance solubility and stability.
- Purity determined by HPLC, reported at 95.36%.
- Molecular weight 578.58 g/mol; formula C30H29F3N6O3.
Medchemexpress LLC Pkiota-in-2 formic | 99.04% | 402.36 | 10 MG
PKCiota-IN-2 formic is a potent inhibitor of PKCiota (IC50 of 2.8 nM), and also inhibits PKC-α (IC50 of 71 nM) and PKC-ε (IC50 of 350 nM). This compound is for research use only.
- Molecular weight of 402.36
- Formula: C25H23N5O3
- Appearance as a solid
- Color ranges from light yellow to yellow
- Soluble in DMSO at 100 mg/mL (248.53 mM); requires ultrasonic
- Ships at room temperature in continental US
- Store at 4°C sealed, away from moisture and light. In solvent, store at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC PKCiota-IN-2 formic | 2230055-52-2 | 99.0% | 402.36 | 25 MG
PKCiota-IN-2 formic is a potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. It also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively. This product is for research use only.
- Appearance: Solid
- Color: Light yellow to yellow
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: 4°C, sealed storage, away from moisture and light. In solvent, store at -80°C for 6 months or -20°C for 1 month (sealed, away from moisture and light).
- Solubility (in vitro): DMSO: 100 mg/mL (248.53 mM; requires ultrasonic).
Medchemexpress LLC Bisindolylmaleimide IX formic | 00-00-0 | 96.0% | 503.57 g/mol | C26H25N5O4S | 5 MG
Ro 31-8220 formic is the formic acid salt of bisindolylmaleimide IX, a potent protein kinase C (PKC) inhibitor provided for laboratory research. The compound is supplied as a small, high-purity solid with manufacturer storage and handling guidance available on the product datasheet.
- Potent PKC inhibitor with low-nanomolar activity.
- Formic acid salt for improved handling and solubility options.
- High purity (≈96.0%).
- Orange to red solid appearance.
- Supplied as a 5 mg vial for research use.
- Recommended storage: sealed, away from moisture, at -20 °C; in solvent, store at -80 °C (up to 6 months) or -20 °C (up to 1 month).
Medchemexpress LLC Bisindolylmaleimide IX formic | 00-00-0 | 96.0% | C26H25N5O4S | 10MG
Ro 31-8220 formic is a small-molecule research reagent that acts as a potent, cell-permeable inhibitor of protein kinase C (PKC) and several other kinases. It is used in biochemical and cellular studies to probe PKC-dependent signaling, kinase selectivity, and downstream pathway effects such as JNK activation and c-Jun induction.
- Potent PKC inhibition with low-nanomolar IC50s.
- Inhibits multiple kinases for broad pathway interrogation.
- Cell-permeable for use in cellular assays.
- High purity solid with characteristic orange to red color.
- Stable when stored sealed at -20°C; in solvent can be stored at -80°C for extended periods.
- Available in small milligram pack sizes suitable for research use.
Medchemexpress LLC BMT-124110 (formic) | 00-00-0 | MFCD34469994 | >98.0% | 369.46 g/mol | C21H27N3O3 | 5 MG
Small-molecule AAK1 inhibitor for laboratory research. It is a potent, selective AAK1 inhibitor (IC50 = 0.9 nM) with reported antinociceptive activity; it also inhibits BIKE (IC50 = 17 nM) and GAK (IC50 = 99 nM). Molecular formula C21H27N3O3; molecular weight 369.46 g/mol. Store powder at -20°C; in solution store at -80°C for up to 6 months or at -20°C for up to 1 month. Purity reported >98% (HPLC).
- Potent AAK1 inhibition (IC50 = 0.9 nM).
- Activity against BIKE and GAK (IC50s 17 nM and 99 nM).
- Suitable for biochemical and cellular kinase assays.
- Stable when stored as powder at -20°C.
- Supplied in milligram research quantities.