Acyl bromides
Apexbio Technology LLC Thonzonium Bromide 553-08-2 1g
Thonzonium Bromide is a surfactant compound identified as an inhibitor of vacuolar ATPase (V-ATPase)-mediated proton transport with an EC50 of approximately 69 M V-ATPase functions as an ATP-dependent proton pump essential for maintaining cellular pH homeostasis by translocating protons across intracellular membranes Investigations show that Thonzonium Bromide disrupts proton translocation without affecting ATP hydrolysis suggesting an uncoupling mechanism of action In cellular studies Thonzonium Bromide reduces cytoplasmic pH levels and inhibits yeast cell growth in a dose-dependent manner It is commonly used as a research tool to study V-ATPase function and to explore cellular processes involving intracellular proton regulation
Cayman Chemical p-Benzoyl-L-phenylalnIn 500mg
A photoreactive derivative of L-phenylalanine; can be incorporated into synthetic peptides and used as a photolabel to identify the residues involved in peptide-protein interactions; has been incorporated into GPCRs to identify potential ligand binding sites
Medchemexpress LLC Cetrimonium bromide-d42 | 907216-28-8 | 99.8% | 406.71 | C19D42BrN | 10 MG
Deuterium-labeled cetrimonium bromide (d42) is a stable isotope-labeled form of the cationic surfactant cetrimonium bromide, supplied for research use as a tracer or internal standard. It is provided as a powder at high purity with defined storage conditions.
- Deuterium labeled (d42) tracer/internal standard.
- Purity 99.8%.
- Molecular formula C19D42BrN; molecular weight 406.71.
- CAS number 907216-28-8.
- Supplied as a powder in small pack sizes (5 mg, 10 mg, 25 mg; larger sizes by inquiry).
- Storage: powder -20°C (3 years); in solvent -80°C (6 months), -20°C (1 month).
AdipoGen 4-ITCB-MPO-pyridinium bromide
Chemical. CAS 155862-90-1. Formula C23H18BrN3O2S. MW 480.38. Synthetic. New class of highly photostable, water soluble fluorescent labels with large Stokes shift, high QY in aqueous media and pH tolerance. Major disadvantage rel. low extinction coefficient.
Medchemexpress LLC Benzoyl coenzyme A trilithium | 102185-37-5 | MFCD00078942 | 94.0% | 889.44 g·mol⁻¹ | C28H37Li3N7O17P3S | 5 MG
Benzoyl coenzyme A trilithium is the trilithium salt of benzoyl coenzyme A supplied for research use as an intermediate in CoA-dependent metabolic pathways (CAS 102185-37-5). It is provided as a white to off-white solid with specified storage and solvent stability for biochemical studies.
- White to off-white solid for biochemical research.
- Molecular weight 889.44 g·mol⁻¹.
- Purity 94.0%.
- Store sealed at -20°C; in solution -80°C (up to 6 months) or -20°C (up to 1 month).
- Used to study benzoate metabolism and CoA-dependent pathways in vitro.
Medchemexpress LLC 2-bromoisobutyryl bromide | 20769-85-1 | MFCD00000122 | ≥98.0% | 229.90 | C4H6Br2O | 500g
2-Bromoisobutyryl bromide (Bromodimethylacetyl bromide -Bromoisobutyryl bromide 2-Bromoisobutylyl bromide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research[1]
Cayman Chemical N-a-Benzoyl-L-ArgInInamIdeh 5g
A nonpeptide substrate of proteases and deiminases; has been used as a substrate for the quantification of papain, carboxypeptidase B, PAD2, and PAD4 activities
Cayman Chemical QX314 bromide Other Receptor
A membrane-impermeant lidocaine derivative that when combined with capsaicin selectively blocks sodium channels on nociceptive neurons via the TRPV1 channel; decreases the pain response without imparting numbness or paralysis associated with other local anesthetics
Medchemexpress LLC N4-Benzoyl-2 -O-meth 500mg
N4-Benzoyl-2 -O-methylcytidine is a natural cytidine nucleoside analog Cytidine analogs have the mechanism of inhibiting DNA methyltransferase (such as Zebularine (HY-13420)) and have potential antimetabolite and antitumor activities[1][2]
AdipoGen 10-Dodecylacridine Orange Br
Chemical. CAS 41387-42-2. Formula C29H44BrN3. MW 514.58. Synthetic. Hydrophobic fluorescent probe. Selectively stains inner mitochondrial membranes, but in contrast to rhodamine-123 staining is not membrane potential-dependent. Dye binding to surfactant micellar surfaces and used for the determination of cationic surfactants.
Medchemexpress LLC 4-(2-Bromoacetyl)benzonitrile | 20099-89-2 | 99.6% | C9H6BrNO | 5 G
4-(2-Bromoacetyl)benzonitrile is a compound that can be used for the synthesis of STA-5312. STA-5312 is a potent and orally active microtubule inhibitor. This product is intended for research use only.
- Solid with an off-white to yellow color
- Can be used for chemical synthesis
- Research use only
Medchemexpress LLC KRN2 bromide | 1390654-28-0 | 98.8% | 524.38 | 1 ML
KRN2 (bromide) is a selective inhibitor of nuclear factor of activated T cells (NFAT5), with an IC50 of 0.1 μM. It is for research use only and not sold to patients.
- Selectively suppresses the expression of pro-inflammatory genes, including Nos2 and Il6.
- Dose-dependently inhibits the NF-κB p65 binding to Nfat5 promoter 1.
- Directly blocks the interaction between NF-κB p65 and its DNA binding sequence.
- Effectively suppresses AIA and CIA in mice.
- Decreases the production of pro-inflammatory cytokines and autoantibodies.
- Reduces macrophage infiltration.
Medchemexpress LLC (2e)-1-(3,4-dimethoxyphenyl)-5-fluoro-3-(4-fluorophenyl)-2-(2-fluorophenyl)pent-1-en-4-one bromide | 1390654-28-0 | >98.8% | 524.38 | 100 MG
KRN2 bromide is a selective inhibitor of nuclear factor of activated T cells (NFAT5), with an IC50 of 0.1 μM. It selectively suppresses the expression of pro-inflammatory genes, including Nos2 and Il6, without hindering high-salt-induced NFAT5 and its target gene expressions. KRN2 also dose-dependently inhibits NF-κB p65 binding to Nfat5 promoter 1 and directly blocks the interaction between NF-κB p65 and its DNA binding sequence in the upstream site of Nfat5 exon 1.
- Effectively suppresses AIA in which innate immune cells play a predominant role.
- Effectively suppresses CIA as well as AIA in mice.
- Decreases the production of pro-inflammatory cytokines and autoantibodies.
- Reduces macrophage infiltration.
Medchemexpress LLC Oleyl bromide ((Z)-1-Bromooctadec-9-ene) | 6110-53-8 | 98.4% | 331.37 | 500 MG
Oleyl bromide ((Z)-1-Bromooctadec-9-ene) is a hydrophobic compound that can carry out ring-opening reactions through a process called "encapsulation." It can also be used as the starting material in the synthesis of oleylphosphonates.
- Hydrophobic compound
- Used in ring-opening reactions
- Starting material for the synthesis of oleylphosphonates
- Appears as a liquid
- Colorless to light yellow in color
Medchemexpress LLC 1,3,5-tri-O-benzoyl-α-D-ribofuranose | 22224-41-5 | 99.8% | 462.45 | 100 G
1,3,5-Tri-O-benzoyl-α-D-ribofuranose is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. This product is intended for research use only and is not sold to patients.
- Targets nucleoside antimetabolite/analog pathways.
- Involved in cell cycle/DNA damage pathways.
- Soluble in DMSO at 100 mg/mL (216.24 mM), requiring ultrasonication.
- Powder is stable for 3 years at -20°C and 2 years at 4°C.
- In solvent, stable for 6 months at -80°C and 1 month at -20°C.