Halomethanes
Medchemexpress LLC Methylene blue | 61-73-4 | 95.0% | C16H18ClN3S | 1 G
Methylene blue is an inhibitor of guanylyl cyclase (sGC), monoamine oxidase A (MAO-A), and NO synthase (NOS). It functions as a vasopressor and is frequently employed as a dye in various medical procedures. This compound is a REDOX cycling compound capable of crossing the blood-brain barrier and has shown to reduce cerebral edema, attenuate microglial activation, and diminish neuroinflammation.
- Inhibits guanylyl cyclase (sGC), monoamine oxidase A (MAO-A), and NO synthase (NOS)
- Functions as a vasopressor
- Employed as a dye in medical procedures
- Influences the nitric oxide synthase/guanylate cyclase signaling pathway
- REDOX cycling compound
- Capable of crossing the blood-brain barrier
- Acts as a Tau aggregation inhibitor
- Reduces cerebral edema
- Attenuates microglial activation
- Diminishes neuroinflammation
eMolecules 75-11-6 | Diiodomethane | Oakwood Chemical | MFCD00001079 | 267.836 | CH2I2 | 98.000 | ICI | 500g | 537691337
Diiodomethane | Oakwood Chemical | 75-11-6 | MFCD00001079 | 267.836 | CH2I2 | 98.000 | ICI | 500g | 537691337
eMolecules 75-11-6 | Diiodomethane | Combi-Blocks | MFCD00001079 | 267.836 | CH2I2 | 98.000 | ICI | 100g | 117543611
Diiodomethane | Combi-Blocks | 75-11-6 | MFCD00001079 | 267.836 | CH2I2 | 98.000 | ICI | 100g | 117543611
Sigma Aldrich Fine Chemicals Biosciences Carbon tetrachloride | 56-23-5 | MFCD00000785 | 1L
Carbon tetrachloride | Purity: ≥99.9% | MW:153.82 | 56-23-5 | MFCD00000785 | 1L
Medchemexpress LLC TEPC466 | 2621957-88-6 | 99.4% | 544.60 | 50 MG
TEPC466 is a novel TEPP-46-based aggregation-induced emission (AIE) probe that shows high selectivity and sensitivity for detecting the PKM2 protein via the AIE effect. It can be used for PKM2 detection and has been successfully applied in imaging the PKM2 protein in colorectal cancer cells with low toxicity. It is a useful tool for cancer diagnosis and research.
- Novel TEPP-46-based aggregation-induced emission (AIE) probe
- High degree of selectivity and sensitivity for the detection of PKM2 protein
- Successfully applied in imaging PKM2 protein in colorectal cancer cells with low toxicity
- Useful tool for cancer diagnosis and research
Medchemexpress LLC Ethanaminium, 2-hydroxy-N-(iodomethyl)-N,N-dimethyl-, iodide | 28508-22-7 | MFCD20489393 | 98.0% | 356.97 | C5H13I2NO | 250 MG
Iodocholine iodide is an iodinated quaternary ammonium reagent used as a metabolizable "green" catalyst for free-radical polymerization and as the non-radioactive iodide analogue of C-11 choline for imaging research. Supplied as a white to off-white solid with high, laboratory-grade purity, it is intended for research applications with recommended storage to preserve stability.
- Iodinated quaternary ammonium salt suitable for polymerization studies.
- Non-radioactive analogue of C-11 choline for PET imaging research.
- High purity (≈98%) for consistent experimental results.
- Solid, white to off-white appearance for easy handling.
- Defined storage conditions to maintain stability.
- Available in multiple pack sizes for flexible ordering.
Medchemexpress LLC Omzotirome | 1092551-88-6 | 99.9% | 328.41 g·mol^-1 | C19H24N2O3 | 50 MG
Omzotirome is a thyromimetic research compound, a functional analog of iodothyronines, used in preclinical studies of lipid metabolism and hyperlipidaemia. It acts as a metabolic modulator that increases energy expenditure and fatty acid oxidation, and is supplied at high chemical purity for laboratory research.
- Used in hyperlipidaemia and metabolic research.
- Acts as a thyromimetic metabolic modulator.
- Increases energy expenditure and fatty acid oxidation in preclinical models.
- Provided in small-scale packaging suitable for bench research.
- Solid form recommended to be stored at 4°C; solutions should be stored frozen.
Medchemexpress LLC N-(4-((4-isopropylpiperazin-1-yl)sulfonylphenyl)-5-pentafluorophenyl)nicotinamide | 1803003-65-7 | 99.9% | 513.54 | 5 MG
RN-1665 is an orally active TRPV4 antagonist that exhibits excellent selectivity for related TRP receptors such as TRPV1, TRPV3, and TRPM8. RN-1665 is a TRPV4 probe for focus screens, with IC50s of 0.26 μM and 0.39 μM for hTRPV4 and rTRPV4 from human and rat, respectively.
- IC50 for human TRPV4 is 0.26 μM.
- IC50 for rat TRPV4 is 0.39 μM.
- Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 minutes.
- Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 minutes.
- Pharmacokinetic analysis has been performed in Wistar rats.
eMolecules 3518-88-5 | Ambeed | Diethyl 33-azanediyldipropanoate | 250mg | 600841193 | A474093 | MFCD14705114 | 217.265 | C10H19NO4
Ambeed | 2-(Bromomethyl)-14-dichlorobenzene | 1g | 532081552 | A710824 | 85482-13-9 | MFCD00236034 | 239.920 | C7H5BrCl2
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eMolecules 558-13-4 | Carbon tetrabromide | Oakwood Chemicals | MFCD00000117 | 331.627 | CBr4 | 99.000 | BrC(Br)(Br)Br | 5g | 480153916
Carbon tetrabromide | Oakwood Chemicals | 558-13-4 | MFCD00000117 | 331.627 | CBr4 | 99.000 | BrC(Br)(Br)Br | 5g | 480153916
![Medchemexpress LLC 3-{[(3,4-dichlorophenyl)amino]carbonyl}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid | 199735-88-1 | MFCD00167693 | >98.0% | 326.17 g·mol⁻¹ | C15H13Cl2NO3 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000242454.png-250.jpg)
Medchemexpress LLC 3-{[(3,4-dichlorophenyl)amino]carbonyl}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid | 199735-88-1 | MFCD00167693 | >98.0% | 326.17 g·mol⁻¹ | C15H13Cl2NO3 | 50 MG
CADD522 is a small-molecule inhibitor of RUNX2-DNA binding used in research to downregulate RUNX2-mediated transcription. It has demonstrated antiproliferative and antimetastatic effects in cell-based and animal cancer studies and is supplied as a solid for laboratory use.
- Inhibits RUNX2-DNA binding with reported IC50 ≈ 10 nM.
- Demonstrated activity in in vitro and in vivo cancer models.
- High purity appropriate for biochemical and cell-based assays.
- Provided in small research quantities for screening and mechanistic studies.
- Stable solid form; store at -20 °C under recommended conditions.
![eMolecules 1128-88-7 | 1-(BENZO[B]THIOPHEN-5-YL)ETHANONE | AstaTech | MFCD16619666 | 176.230 | C10H8OS | 95.000 | CC(=O)c1ccc2sccc2c1 | 0.25g | 381448158](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502457283.PNG-250.jpg)
eMolecules 1128-88-7 | 1-(BENZO[B]THIOPHEN-5-YL)ETHANONE | AstaTech | MFCD16619666 | 176.230 | C10H8OS | 95.000 | CC(=O)c1ccc2sccc2c1 | 0.25g | 381448158
1-(BENZO[B]THIOPHEN-5-YL)ETHANONE | AstaTech | 1128-88-7 | MFCD16619666 | 176.230 | C10H8OS | 95.000 | CC(=O)c1ccc2sccc2c1 | 0.25g | 381448158
eMolecules 1343722-88-2 | ChemScene | 4-Chloro-2-fluorobenzothioamide | 250mg | 572194186 | CS-0114061 | MFCD17290209 | 189.63 | C7H5ClFNS
ChemScene | Sodium tetrahydrofuran-3-sulfinate | 250mg | 801476584 | CS-0530358 | 1622013-59-5 | MFCD28124335 | 158.150 | C4H7NaO3S
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