Halomethanes
Medchemexpress LLC CHI-KAT8i5 | 98.0% | 523.69 | 25 MG
CHI-KAT8i5 is a selective and orally active KAT8 inhibitor that induces cancer cell apoptosis and suppresses esophageal squamous cell carcinoma (ESCC) growth by targeting the KAT8/c-Myc signaling pathway. It is a white to off-white solid.
- Selective KAT8 inhibitor
- Induces cancer cell apoptosis
- Suppresses ESCC tumor growth
- Soluble in DMSO at 100 mg/mL
- Stable as powder for up to 3 years
eMolecules 36316-88-8 | Ambeed | 26-Diiodonaphthalene | 100mg | 633419946 | A408537 | MFCD17012279 | 379.967 | C10H6I2
Ambeed | (S)-4-(5-Chloro-2-(isopropylamino)pyridin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide | 10mg | 552603369 | A162263 | 869886-67-9 | MFCD22628898 | 433.330 | C21H22Cl2N4O2
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Medchemexpress LLC Methylene blue | 61-73-4 | 95.0% | C16H18ClN3S | 500 MG
Methylene blue is a chemical compound frequently used as a dye in medical procedures and functions as a vasopressor. It acts as an inhibitor for guanylyl cyclase (sGC), monoamine oxidase A (MAO-A), and NO synthase (NOS). Methylene blue influences the nitric oxide synthase/guanylate cyclase signaling pathway and is capable of crossing the blood-brain barrier. It also functions as a Tau aggregation inhibitor, demonstrating potential in reducing cerebral edema, attenuating microglial activation, and diminishing neuroinflammation.
- Inhibits sGC, MAO-A, and NOS pathways
- Used as a vasopressor and medical dye
- Influences nitric oxide synthase/guanylate cyclase signaling
- Crosses the blood-brain barrier
- Functions as a Tau aggregation inhibitor
- Reduces cerebral edema and neuroinflammation
![Medchemexpress LLC N-[5-({2-[(cyclopropylcarbonyl)amino]-imidazo[1,2-b]pyridazin-6-yl}oxy)-2-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-... | 1005780-62-0 | MFCD23160045 | 99.7% | 445.47 g·mol⁻1 | C23H23N7O3 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000287464.png-250.jpg)
Medchemexpress LLC N-[5-({2-[(cyclopropylcarbonyl)amino]-imidazo[1,2-b]pyridazin-6-yl}oxy)-2-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-... | 1005780-62-0 | MFCD23160045 | 99.7% | 445.47 g·mol⁻1 | C23H23N7O3 | 10 MG
TAK-593 is a small-molecule tyrosine kinase inhibitor originally developed by Takeda Pharmaceutical Company. It potently inhibits vascular endothelial growth factor receptors and platelet-derived growth factor receptors and has demonstrated anti-angiogenic and antitumor activity in preclinical studies. Reported biochemical IC50 values include 3.2 nM (VEGFR1), 0.95 nM (VEGFR2), 1.1 nM (VEGFR3), 4.3 nM (PDGFRα), and 13 nM (PDGFRβ).
- Potent VEGFR and PDGFR inhibition (VEGFR2 IC50 ≈ 0.95 nM).
- High biochemical selectivity toward receptor tyrosine kinases.
- Reported molecular formula C23H23N7O3 and molecular weight ≈ 445.47 g·mol⁻1.
- High purity, typically reported as 99.66% by supplier.
- Provided with analytical documentation such as LC-MS.
- Suitable for preclinical studies of angiogenesis and tumor biology.
![eMolecules 13237-88-2 | 7-bromobicyclo[2.2.1]heptane | Synthonix175.069 | C7H11Br | 99.000 | BrC1C2CCC1CC2 | 500mg | 784552152](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502464460.JPG-250.jpg)
eMolecules 13237-88-2 | 7-bromobicyclo[2.2.1]heptane | Synthonix175.069 | C7H11Br | 99.000 | BrC1C2CCC1CC2 | 500mg | 784552152
7-bromobicyclo[2.2.1]heptane | Synthonix | 13237-88-2175.069 | C7H11Br | 99.000 | BrC1C2CCC1CC2 | 500mg | 784552152
Medchemexpress LLC 2-cyclohexen-1-one, 3-(15-hydroxypentadecyl)-2,4,4-trimethyl- | 220757-88-0 | 99.1% | 364.60 | C24H44O2 | 10 MG
tCFA15 is a trimethyl cyclohexenonic long-chain fatty alcohol (C24H44O2, MW 364.60) that promotes neuronal differentiation and modulates Notch1 signaling. It is supplied as a high-purity research standard intended for in vitro studies of neural stem cell differentiation and neuronal signaling pathways.
- Promotes differentiation of neural stem cell-derived neurospheres toward neurons.
- Modulates Notch1 expression and signaling.
- High purity suitable for in vitro research applications.
- Soluble in DMSO for solution-based assays.
- Shown to stimulate arginine vasopressin secretion in neurohypophysis preparations.
Medchemexpress LLC RN-1665 | 1803003-65-7 | 99.93% | 513.54 | 100 MG
RN-1665 is an orally active TRPV4 antagonist that exhibits excellent selectivity for related TRP receptors such as TRPV1, TRPV3, and TRPM8. It serves as a TRPV4 probe for focused screens, showing IC50s of 0.26 μM for human TRPV4 and 0.39 μM for rat TRPV4.
- Orally active.
- TRPV4 antagonist.
- Exhibits excellent selectivity for related TRP receptors such as TRPV1, TRPV3, and TRPM8.
- Functions as a TRPV4 probe for focus screens.
- Has an IC50 of 0.26 μM for human TRPV4.
- Has an IC50 of 0.39 μM for rat TRPV4.
![eMolecules 112892-88-3 | ChemScene | Bicyclo[4.2.0]octa-135-triene-3-carbaldehyde | 250mg | 632277807 | CS-0044063 | MFCD09842341 | 132.162 | C9H8O](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502442815.PNG-250.jpg)
eMolecules 112892-88-3 | ChemScene | Bicyclo[4.2.0]octa-135-triene-3-carbaldehyde | 250mg | 632277807 | CS-0044063 | MFCD09842341 | 132.162 | C9H8O
Ambeed | 4-Methoxy-2-(4455-tetramethyl-132-dioxaborolan-2-yl)benzaldehyde | 100mg | 789350278 | A797455 | 1196474-59-5 | MFCD16658743 | 262.110 | C14H19BO4
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eMolecules 1416444-88-6 | ChemScene | (R)-(66-Dimethylmorpholin-2-yl)methanol hydrochloride | 100mg | 569146498 | CS-0129999 | MFCD22690353 | 181.66 | C7H16ClNO2
ChemScene | 1-(3-Methoxyphenyl)butan-1-amine hydrochloride | 100mg | 714105315 | CS-0497690 | 1864057-25-9 | MFCD28126397 | 215.720 | C11H18ClNO
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eMolecules 593-71-5 | CHLOROIODOMETHANE | AstaTech | MFCD00001078 | 176.380 | CH2ClI | 95.000 | ClCI | 100g | 696740304
CHLOROIODOMETHANE | AstaTech | 593-71-5 | MFCD00001078 | 176.380 | CH2ClI | 95.000 | ClCI | 100g | 696740304
Medchemexpress LLC 3-(15-hydroxypentadecyl)-2,4,4-trimethylcyclohex-2-en-1-one | 220757-88-0 | MFCD09832597 | 99.1% | 364.60 g/mol | C24H44O2 | 50 MG
tCFA15 is a trimethyl cyclohexenonic long-chain fatty alcohol (IUPAC: 3-(15-hydroxypentadecyl)-2,4,4-trimethylcyclohex-2-en-1-one; CAS 220757-88-0) used as a research reagent to promote neuronal differentiation and modulate Notch signaling. It is supplied as an analytical standard and characterized for in vitro biochemical and cell-based assays.
- High purity (99.12% by LCMS).
- Molecular weight 364.60 g/mol.
- Soluble in DMSO.
- Suitable for neuronal differentiation and Notch signaling studies.
- Provided as an analytical standard for HPLC, GC, and MS methods.
Medchemexpress LLC Methylene blue | 61-73-4 | MFCD00012111 | 95.0% | C16H18ClN3S | 100 MG
Methylene blue is an inhibitor of guanylyl cyclase (sGC), monoamine oxidase A (MAO-A), and NO synthase (NOS). It acts as a vasopressor and is commonly used as a dye in various medical procedures. This REDOX cycling compound is capable of crossing the blood-brain barrier and is also a Tau aggregation inhibitor. It helps reduce cerebral edema, mitigate microglial activation, and decrease neuroinflammation.
- Inhibits guanylyl cyclase (sGC), monoamine oxidase A (MAO-A), and NO synthase (NOS)
- Acts as a vasopressor
- Commonly used as a dye in medical procedures
- Impacts prepulse inhibition through the nitric oxide synthase/guanylate cyclase signaling pathway
- Functions as a REDOX cycling compound
- Capable of crossing the blood-brain barrier
- Acts as a Tau aggregation inhibitor
- Helps reduce cerebral edema
- Mitigates microglial activation
- Decreases neuroinflammation