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Filtered Search Results
eMolecules 308795-91-7 | 3-Methyl-2-pyridylzinc bromide, 0.50 M in THF | Synthonix237.410 | C6H6BrNZn | 0.000 | [Br-].Cc1cccnc1[Zn+] | 100ml | 532652907
3-Methyl-2-pyridylzinc bromide, 0.50 M in THF | Synthonix | 308795-91-7237.410 | C6H6BrNZn | 0.000 | [Br-].Cc1cccnc1[Zn+] | 100ml | 532652907
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eMolecules Synthonix Hexylzinc iodide 0.50 M in THF 25ml 627353663 H73283 152329-33-4 [null] 277.450 C6H13IZn
Synthonix Hexylzinc iodide 0.50 M in THF 25ml 627353663 H73283 152329-33-4 [null] 277.450 C6H13IZn
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eMolecules 2144836-81-5 | (3-(Benzyloxy)propyl)magnesium bromide, 0.5 M in THF | Synthonix253.422 | C10H13BrMgO | 0.000 | [Br-].[Mg+]CCCOCc1ccccc1 | 100ml | 771375793
(3-(Benzyloxy)propyl)magnesium bromide, 0.5 M in THF | Synthonix | 2144836-81-5253.422 | C10H13BrMgO | 0.000 | [Br-].[Mg+]CCCOCc1ccccc1 | 100ml | 771375793
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eMolecules 7353-91-5 | 4-(Dimethylamino)phenylmagnesium bromide, 0.5M in THF | Synthonix - Stock | MFCD00672006 | 224.384 | C8H10BrMgN | 0.000 | [Br-].CN(C)c1ccc([Mg+])cc1 | 500ml | 437237122
4-(Dimethylamino)phenylmagnesium bromide, 0.5M in THF | Synthonix - Stock | 7353-91-5 | MFCD00672006 | 224.384 | C8H10BrMgN | 0.000 | [Br-].CN(C)c1ccc([Mg+])cc1 | 500ml | 437237122
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Medchemexpress LLC SK-575 | 2523016-96-6 | 99.9% | 876.97 | 25 MG
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SK-575 is a highly potent and specific proteolysis-targeting chimera (PROTAC) degrader of PARP1, with an IC50 of 2.30 nM. It potently inhibits the growth of cancer cells bearing BRCA1/2 mutations.
- Potently inhibits the growth of cancer cells bearing BRCA1/2 mutations.
- Shows good PARP1 degradation activity in cancer cell lines.
- Effectively induces the formation of γH2AX in MDA-MB-436 and Capan-1 cells in a dose-dependent manner.
- Significantly inhibits tumor growth in HR-deficient xenograft models.
- Achieves sufficient plasma exposure and effectively induces PARP1 degradation in tumor tissue.
- Well tolerated in animal models.
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eMolecules 33527-91-2 | Tris(2-dimethylaminoethyl)amine | Combi-Blocks | MFCD00015607 | 230.400 | C12H30N4 | 95.000 | CN(C)CCN(CCN(C)C)CCN(C)C | 1g | 439372950
Tris(2-dimethylaminoethyl)amine | Combi-Blocks | 33527-91-2 | MFCD00015607 | 230.400 | C12H30N4 | 95.000 | CN(C)CCN(CCN(C)C)CCN(C)C | 1g | 439372950
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Medchemexpress LLC Siramesine (hydrochloride) | 224177-60-0 | 99.7% | C30H32ClFN2O | 1 ML
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Siramesine hydrochloride is a potent sigma-2 receptor agonist with subnanomolar affinity (IC50=0.12 nM), showing significant selectivity over sigma-1 receptors. This compound triggers cell death by destabilizing mitochondria and demonstrates anti-cancer activity.
- Potent sigma-2 receptor agonist
- Subnanomolar affinity for sigma-2 receptors
- High selectivity over sigma-1 receptors
- Triggers cell death through mitochondrial destabilization
- Exhibits anti-cancer activity
- Induces cell death in various cell lines
- Activates caspases in HaCaT and U-87MG cells
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eMolecules 103068-18-4 | 3-Biphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock257.413 | C12H9BrMg | 0.000 | [Br-].[Mg+]c1cccc(c1)-c1ccccc1 | 100ml | 437236966
3-Biphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 103068-18-4257.413 | C12H9BrMg | 0.000 | [Br-].[Mg+]c1cccc(c1)-c1ccccc1 | 100ml | 437236966
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eMolecules 2265921-89-7 | (Tetrahydrothiopyran-4-yl)magnesium bromide, 0.50 M in THF | Synthonix - Stock205.400 | C5H9BrMgS | 95.000 | [Br-].[Mg+]C1CCSCC1 | 50ml | 379648617
(Tetrahydrothiopyran-4-yl)magnesium bromide, 0.50 M in THF | Synthonix - Stock | 2265921-89-7205.400 | C5H9BrMgS | 95.000 | [Br-].[Mg+]C1CCSCC1 | 50ml | 379648617
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Medchemexpress LLC Teslexivir hydrochloride | 1075281-70-7 | 98.3% | 679.04 | 1 ML
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Teslexivir (BTA074) hydrochloride is a potent antiviral agent. It acts as a potent and selective inhibitor of the interaction between two essential viral proteins, E1 and E2, which is a necessary step in the DNA replication and viral production for Human Papilloma Virus (HPV) 6 and 11. Teslexivir hydrochloride is suitable for condyloma research.
- Potent antiviral agent.
- Selective inhibitor of the interaction between viral proteins E1 and E2.
- Disrupts DNA replication and viral production for Human Papilloma Virus (HPV) 6 and 11.
- Can be used for condyloma research.
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Medchemexpress LLC BI-3663 | 2341740-84-7 | 99.8% | 917.84 | 1 MG
Small and Specialty Supplier Partner
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BI-3663 is a highly selective PTK2/FAK PROTAC that utilizes Cereblon ligands to hijack E3 ligases for PTK2 degradation. It inhibits PTK2 with an IC50 of 18 nM and demonstrates anti-cancer activity. It potently degrades PTK2 in Hep3B2.1-7 cells and A549 cells, with pDC50s of 7.6 and 7.9, respectively.
- Highly selective PTK2/FAK PROTAC
- Utilizes Cereblon ligands for PTK2 degradation
- Inhibits PTK2 with an IC50 of 18 nM
- Demonstrates anti-cancer activity
- Potently degrades PTK2 in Hep3B2.1-7 cells and A549 cells
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eMolecules [3-(2-Adamantyl)-4-methoxyphenyl]magnesium bromide, 0.5 M in THF | Synthonix |345.563 | C17H21BrMgO | 0.000 | [Br-].COc1ccc([Mg+])cc1C1C2CC3CC(C2)CC1C3 | 100ml | 818571992
[3-(2-Adamantyl)-4-methoxyphenyl]magnesium bromide, 0.5 M in THF | Synthonix |345.563 | C17H21BrMgO | 0.000 | [Br-].COc1ccc([Mg+])cc1C1C2CC3CC(C2)CC1C3 | 100ml | 818571992
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eMolecules Ambeed Tetraoctylammonium bromide 10g 552726098 A408773 14866-33-2 MFCD00011863 546.807 C32H68BrN
Ambeed Tetraoctylammonium bromide 10g 552726098 A408773 14866-33-2 MFCD00011863 546.807 C32H68BrN
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eMolecules 103068-18-4 | 3-Biphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock257.413 | C12H9BrMg | 0.000 | [Br-].[Mg+]c1cccc(c1)-c1ccccc1 | 50ml | 437236965
3-Biphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 103068-18-4257.413 | C12H9BrMg | 0.000 | [Br-].[Mg+]c1cccc(c1)-c1ccccc1 | 50ml | 437236965
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eMolecules (6-Methoxycarbonyl-2-naphthyl)zinc bromide, 0.5 M in THF | Synthonix |330.490 | C12H9BrO2Zn | 0.000 | [Br-].COC(=O)c1ccc2cc([Zn+])ccc2c1 | 100ml | 812584987
(6-Methoxycarbonyl-2-naphthyl)zinc bromide, 0.5 M in THF | Synthonix |330.490 | C12H9BrO2Zn | 0.000 | [Br-].COC(=O)c1ccc2cc([Zn+])ccc2c1 | 100ml | 812584987
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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