Naphthalenes

Polycyclic aromatic hydrocarbon compounds that consist of ten carbon atoms and eight hydrogen atoms fused into two benzene rings; it is the simplest polycyclic aromatic hydrocarbon.

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2,011 – 2,025 of 4,900 results

2,011

Medchemexpress LLC Siglec-10 Human Bi 50ug | 50ug

Siglec-10 protein is thought to be a putative adhesion molecule that mediates sialic acid-dependent cell binding preferentially selecting -2 3- or -2 6-linked sialic acid Its sialic acid recognition site may be masked by cis interactions Siglec-10 Protein Human (Biotinylated R119A HEK293 His-Avi) is the recombinant human-derived Siglec-10 protein expressed by HEK293 with C-Avi C-His labeled tag

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2,012

Medchemexpress LLC MEDCHEMEXPRESS LLC

5000757319 2-ACETYL-1-NAPHTHOL 25G

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2,013

Medchemexpress LLC Idarubicin hydrochloride | 57852-57-0 | 99.8% | 533.95 | 25 MG

Anthracycline antileukemic agent
Inhibits topoisomerase II
Interferes with DNA replication and RNA transcription
Inhibits the growth of bacteria and yeasts
Shown greater cytotoxicity than daunorubicin or doxorubicin in various in vitro systems
Better ability to induce the formation of topoisomerase II-mediated DNA breaks
Produces a concentration-dependent reduction in cell growth
Produces a concentration-dependent inhibition of DNA synthesis

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2,014

Medchemexpress LLC Butenafine Hydrochloride | 101827-46-7 | 99.9% | 353.93 | 5 G

Butenafine Hydrochloride | 101827-46-7 | 99.9% | 353.93 | 5 G

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2,015

Medchemexpress LLC Idarubicin hydrochloride | 57852-57-0 | 99.9% | 533.95 | 100 MG

Idarubicin hydrochloride is an anthracycline antileukemic agent that inhibits topoisomerase II, interfering with DNA replication and RNA transcription. It also inhibits the growth of bacteria and yeasts. This agent has demonstrated greater cytotoxicity than daunorubicin or doxorubicin in various in vitro systems, attributed to a better ability to induce topoisomerase II-mediated DNA breaks.

Inhibits topoisomerase II, interfering with DNA replication and RNA transcription
Inhibits the growth of bacteria and yeasts
Greater cytotoxicity than daunorubicin or doxorubicin
Induces topoisomerase II-mediated DNA breaks
Produces concentration-dependent reduction in cell growth
Inhibits DNA synthesis

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2,016

Medchemexpress LLC Irinotecan hydrochloride trihydrate | 136572-09-3 | 99.9% | 677.18 | 1 ML

Irinotecan hydrochloride, also known as (+)-Irinotecan hydrochloride or CPT-11 hydrochloride, is a topoisomerase I inhibitor primarily used in the treatment of colon and rectal cancer. This product is intended for research use only.

Acts as an inhibitor of topoisomerase I, an enzyme crucial for DNA replication, transcription, and repair.
Effectively inhibits the growth of various cancer cell lines.
Suppresses the proliferation of human umbilical vein endothelial cells (HUVEC).
Significantly inhibits tumor growth in animal models.
Involved in numerous clinical trials for a wide range of cancers.

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2,017

Medchemexpress LLC Olodaterol hydrochl 10mM | 10MM/1ML

Olodaterol hydrochl 10mM | 10MM/1ML

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2,018

Medchemexpress LLC N#CC1=C(N)SC2=C1[C@]3(CCC2)C4=C(CCC3)C(C5=NC(N6[C@H](CNCC6)C)=NC=C5)=NO4 | 2937344-16-4 | 99.8% | 461.58 g/mol | C24H27N7OS | 10 MG

BI-2493 is a small-molecule pan-KRAS inhibitor supplied for research use. It is reported to be highly selective and orally active, and has demonstrated concentration-dependent inhibition of KRAS-mutant cell proliferation in vitro and tumor-suppressive activity in multiple xenograft models in vivo.

Highly selective, orally active pan-KRAS inhibitor.
Inhibits proliferation of KRAS mutant cancer cell lines in vitro.
Exhibits tumor-suppressive activity in mouse xenograft models.
Reported purity 99.79% and molecular weight 461.58 g/mol.
Available in multiple formats and quantities, including 10 mg and 10 mM solutions in DMSO.
Supplied for research use only; not for human use.

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2,019

eMolecules 142929-48-4 | ChemScene | tert-Butyl 3-oxomorpholine-4-carboxylate | 250mg | 536785355 | CS-0039097 | MFCD09751120 | 201.222 | C9H15NO4

Medchem Express | MRTF|SRF-IN-1 | 5mg | 788478539 | HY-153078 | 1922098-90-5 | 473.880 | C24H19ClF3N3O2

If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>

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2,020

Medchemexpress LLC Quinpirole (hydrochloride) | 85798-08-9 | 25 MG

Quinpirole hydrochloride is a high-affinity agonist of the dopamine D2/D3 receptor. It is also known as LY 171555 hydrochloride or (-)-LY 141865 hydrochloride. Quinpirole (LY 171555) is a dopamine D2/D3 receptor agonist that can reduce hypothalamic norepinephrine concentrations. Its effects, which include a decrease in dopamine metabolites and a possible increase in MHPG sulfate by enhancing norepinephrine release, are not replicated by the selective D1 agonist SKF 38393 or the dextrorotatory isomer of Quinpirole, which lacks D2 agonist activity.

High-affinity agonist of dopamine D2/D3 receptor.
Reduces hypothalamic norepinephrine concentrations.
Leads to a decrease in dopamine metabolites.
May increase MHPG sulfate by enhancing norepinephrine release.

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2,021

Medchemexpress LLC Heptaminol hydrochloride | 543-15-7 | 98.0% | 25 MG

Heptaminol hydrochloride (RP-2831) is a vasoconstrictor studied for its use in hypotension, especially orthostatic hypotension. It also acts as a skin cancer proliferation inhibitor by hindering immune inflammation induced by the tumor-promoting factor 12-O-tetradecanoylphorbol-13-acetate (TPA) in an NO-dependent manner. Additionally, it functions as a sympathomimetic amine, exhibiting indirect sympathetic effects, and is an antagonist of catecholamine release and uptake, which can elevate intracellular free calcium levels.

Vasoconstrictor for hypotension studies.
Inhibits skin cancer proliferation.
Acts as a sympathomimetic amine.
Antagonist of catecholamine release and uptake.
Increases intracellular free calcium levels.
Demonstrates anti-proliferative and anti-inflammatory effects.

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2,022

TARGETMOL CHEMICALS INC DESERPIDINE 5MG

Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Deserpidine (Harmonyl) is only found in individuals that have used or taken this drug. It is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive properties that has been used for the control of high blood pressure and for the relief of psychotic behavior.Deserpidine's mechanism of action is through inhibition of the ATP/Mg2+ pump responsible for the sequestering of neurotransmitters into storage vesicles located in the presynaptic neuron. Deserpidine is a competitive angiotensin converting enzyme (ACE) inhibitor. Deserpidine also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex. purity: 98%

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2,023

Medchemexpress LLC Amantadine hydrochloride | 665-66-7 | 98.0% | 5 G

Amantadine hydrochloride is an orally active and potent antiviral agent, effective against influenza A viruses. It inhibits various ion channels, including NMDA, M2, and Coronavirus ion channels. The compound also demonstrates anti-orthopoxvirus and anticancer activities, and is utilized in research for Parkinson's disease, postoperative cognitive dysfunction (POCD), and COVID-19.

Potent antiviral agent, effective against influenza A viruses and SARS-CoV-2 replication
Inhibits various ion channels, including NMDA, M2, and Coronavirus
Exhibits anti-orthopoxvirus and anticancer activities
Used in research for Parkinson's disease, postoperative cognitive dysfunction, and COVID-19
Induces apoptosis and arrests cell cycle in cancer cells
Inhibits surgery-induced neuroinflammation and learning/memory impairment

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2,024

Medchemexpress LLC BI-4020 | 2664214-60-0 | 99.3% | 10 MG

BI-4020 is a fourth-generation, orally active, and non-covalent EGFR tyrosine kinase inhibitor. It inhibits the triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM in BaF3 cell lines), the double mutant EGFR del19 T790M, and primary mutant EGFR del19 (IC50=1 nM). It also shows activity against EGFR wt (IC50=190 nM). This product demonstrates high kinome selectivity and good DMPK properties and is for research use only.

Fourth-generation, orally active, and non-covalent EGFR tyrosine kinase inhibitor
Inhibits triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM)
Inhibits double mutant EGFR del19 T790M and primary mutant EGFR del19 (IC50=1 nM)
Shows activity against EGFR wt (IC50=190 nM)
Demonstrates high kinome selectivity and good DMPK properties
Leads to tumor regressions in human PC-9 triple mutant NSCLC xenograft model in mice

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2,025

eMolecules 59107-51-6 | 8-Chloro-naphthalen-1-ylamine | J & W PharmLab LLC | MFCD00465087 | 177.630 | C10H8ClN | 96.000 | Nc1cccc2cccc(Cl)c12 | 1g | 525292172

8-Chloro-naphthalen-1-ylamine | J & W PharmLab LLC | 59107-51-6 | MFCD00465087 | 177.630 | C10H8ClN | 96.000 | Nc1cccc2cccc(Cl)c12 | 1g | 525292172

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Naphthalenes

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Medchemexpress LLC Siglec-10 Human Bi 50ug | 50ug Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC MEDCHEMEXPRESS LLC Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Idarubicin hydrochloride | 57852-57-0 | 99.8% | 533.95 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Butenafine Hydrochloride | 101827-46-7 | 99.9% | 353.93 | 5 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Idarubicin hydrochloride | 57852-57-0 | 99.9% | 533.95 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Irinotecan hydrochloride trihydrate | 136572-09-3 | 99.9% | 677.18 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Olodaterol hydrochl 10mM | 10MM/1ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC N#CC1=C(N)SC2=C1[C@]3(CCC2)C4=C(CCC3)C(C5=NC(N6[C@H](CNCC6)C)=NC=C5)=NO4 | 2937344-16-4 | 99.8% | 461.58 g/mol | C24H27N7OS | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Quinpirole (hydrochloride) | 85798-08-9 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Heptaminol hydrochloride | 543-15-7 | 98.0% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

TARGETMOL CHEMICALS INC DESERPIDINE 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Amantadine hydrochloride | 665-66-7 | 98.0% | 5 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BI-4020 | 2664214-60-0 | 99.3% | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More