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Filtered Search Results
Medchemexpress LLC Fluoxetine hydrochloride | 56296-78-7 | 100.0% | C17H19ClF3NO | 500 MG
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Fluoxetine hydrochloride is an antidepressant and a selective serotonin reuptake inhibitor, intended for research use only.
- Acts as an antidepressant and selective serotonin reuptake inhibitor.
- Blocks downregulation of cell proliferation in hippocampal cells.
- Increases neurogenesis in the hippocampus and prelimbic cortex.
- Enhances neurogenesis-dependent long-term potentiation.
- Increases norepinephrine and dopamine extracellular levels.
- Reverses deficits in escape latency in animal models.
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Medchemexpress LLC Fluoxetine hydrochloride | 56296-78-7 | 100.0% | C17H19ClF3NO | 100 MG
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Fluoxetine hydrochloride (LY 110140) is an antidepressant and a selective serotonin reuptake inhibitor. It exhibits potent inhibitory activity against human SERT (serotonin reuptake transporter) in HEK293 cells with an IC50 of 150 nM. This product is for research use only.
- Selective serotonin reuptake inhibitor
- Potent inhibitory activity against human SERT in HEK293 cells (IC50: 150 nM)
- Blocks downregulation of cell proliferation in hippocampal cells
- Increases newborn cells in the dentate gyrus of adult rat hippocampus
- Enhances neurogenesis-dependent long-term potentiation (LTP)
- Increases extracellular norepinephrine and dopamine levels in the prefrontal cortex
- Reverses escape latency deficits in rat models of inescapable shock
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Cayman Chemical 6-methoxy-2-NaphthoIc AcId 1g
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An active metabolite of nabumetone; inhibits COX-1 and LPS-induced COX-2 activities in isolated human whole blood (IC50s = 31.01 and 19.84 µM, respectively); a potential impurity in commercial preparations of naproxen
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Medchemexpress LLC Adapalene (CD271) | 106685-40-9 | 99.9% | C28H28O3 | 500 MG
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Adapalene (CD271) is a third-generation synthetic retinoid primarily used for acne research. It functions as a potent RAR agonist and non-competitively inhibits GOT1 enzymatic activity, also demonstrating anti-tumor properties.
- Acts as a potent RAR agonist with varying AC50s for RAR subtypes.
- Inhibits viability of various cancer cell lines.
- Induces apoptosis and inhibits proliferation in ES-2 cells.
- Increases G1-phase population in LoVo or DLD1 cells.
- Inhibits GOT1 activity.
- Inhibits expression of plasma membrane-associated enzyme transglutaminase Type I.
- Inhibits growth of DLD1 cell-derived xenograft tumors in BALB/C nude mice, reducing tumor weight and volume.
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Selleck Chemical LLC BI-0474-E1356-1MG
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BI-0474 is a potent inhibitor of KRASG12C with an IC50 value of 7 0 nM It inhibits GDP-KRAS SOS1 protein-protein interactions It exhibits anti-proliferative and anti-tumour activity and can be used in cancer research
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Cayman Chemical Naphthol AS-BI-Phosphate 5g
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A fluorogenic substrate for acid and alkaline phosphatases; is converted to N-ASBI which displays ex/em spectra of 405/515 nm, respectively; fluorescence is a quantitative marker of acid and alkaline phosphatase activity
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Medchemexpress LLC Siglec-10 Human Bi 50ug | 50ug
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Siglec-10 protein is thought to be a putative adhesion molecule that mediates sialic acid-dependent cell binding preferentially selecting -2 3- or -2 6-linked sialic acid Its sialic acid recognition site may be masked by cis interactions Siglec-10 Protein Human (Biotinylated R119A HEK293 His-Avi) is the recombinant human-derived Siglec-10 protein expressed by HEK293 with C-Avi C-His labeled tag
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(CCCC)c1ncncc1Br | 250mg | 525910903](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502446253.PNG-250.jpg)
eMolecules 1416437-21-2 | 5-Bromo-4-(tributylstannyl)pyrimidine | Synthonix - Stock | MFCD16170450 | 448.036 | C16H29BrN2Sn | 94.000 | CCCC[Sn](CCCC)(CCCC)c1ncncc1Br | 250mg | 525910903
5-Bromo-4-(tributylstannyl)pyrimidine | Synthonix - Stock | 1416437-21-2 | MFCD16170450 | 448.036 | C16H29BrN2Sn | 94.000 | CCCC[Sn](CCCC)(CCCC)c1ncncc1Br | 250mg | 525910903
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Medchemexpress LLC HY-103617 5mg Medchemexpress, PKM2-IN-1 CAS:94164-88-2 Purity:>98%
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Medchemexpress, HY-103617 5mg PKM2-IN-1 CAS:94164-88-2 PKM2-IN-1 is a pyruvate kinase M2 (PKM2) inhibitor with an IC50 of 2.95 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Atrasentan hydrochloride | 195733-43-8 | C29H39ClN2O6 | 100 MG
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Atrasentan hydrochloride is a selective endothelin A receptor antagonist, exhibiting an IC50 of 0.0551 nM for ETA. It is designated for research purposes only and is not intended for patient use. This compound presents as an off-white to gray solid with a molecular weight of 547.08.
- Effectively inhibits the growth of LNCaP and C4-2b prostate cancer cells.
- Significantly induces several CYPs and drug transporters.
- Acts as a moderate P-gp inhibitor and a weak BCRP inhibitor.
- Suppresses pressor response initiated by big endothelin-1 in pithed rats.
- Partially inhibits C4-2b tumor progression within the bone environment in the SCID-hu model.
- Soluble in DMSO and water with specific preparation requirements.
- Recommended storage at 4°C in sealed conditions, away from moisture.
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Medchemexpress LLC Naphthalene-2,3-dicarboxaldehyde | 7149-49-7 | MFCD00016618 | 99.4% | 184.19 | C12H8O2 | 500 MG
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Naphthalene-2,3-dicarboxaldehyde is an aromatic dialdehyde used as a reagent in analytical and biochemical research. It is commonly used for fluorogenic derivatization of primary amines and for sensitive detection in assays. The compound is supplied as a high-purity solid with supporting documentation for research use.
- High purity suitable for analytical applications.
- Fluorogenic derivatization reagent for primary amines.
- Supplied as a stable solid for convenient handling and storage.
- Available in multiple pack sizes to support varied research needs.
- Accompanied by datasheet and certificate of analysis documentation.
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eMolecules 3886-70-2 | (1R)-1-(naphthalen-1-yl)ethan-1-amine | Pharmablock | MFCD00064114 | 171.243 | C12H13N | 97.000 | C[C@@H](N)c1cccc2ccccc12 | 250mg | 551221652
(1R)-1-(naphthalen-1-yl)ethan-1-amine | Pharmablock | 3886-70-2 | MFCD00064114 | 171.243 | C12H13N | 97.000 | C[C@@H](N)c1cccc2ccccc12 | 250mg | 551221652
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Medchemexpress LLC Ombrabulin hydrochloride | 253426-24-3 | 99.4% | 438.90 | 100 MG
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Ombrabulin hydrochloride is a derivative of CA-4 phosphate, known to exhibit antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial cells. It acts as a tubulin inhibitor, demonstrating potent cytotoxicity against various cancer cell lines and showing efficacy in reducing tumor weight in vivo.
- Acts as a tubulin inhibitor
- Exhibits antivascular effects
- Disrupts the tubulin cytoskeleton of endothelial cells
- Shows cytotoxicity against DU-145, HeLa, MCF7, NCI-H460, and SK-OV-3 cell lines
- Proven effective in reducing tumor weight in animal models
- Tested in clinical trials for solid tumors and various cancers
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eMolecules 1141-38-4 | Naphthalene-2,6-dicarboxylic acid | Synthonix | MFCD00004105 | 216.192 | C12H8O4 | 97.000 | OC(=O)c1ccc2cc(ccc2c1)C(O)=O | 100g | 779541442
Naphthalene-2,6-dicarboxylic acid | Synthonix | 1141-38-4 | MFCD00004105 | 216.192 | C12H8O4 | 97.000 | OC(=O)c1ccc2cc(ccc2c1)C(O)=O | 100g | 779541442
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![eMolecules 1589-82-8 | Benzylmagnesium bromide, 1.0 M in 2-MeTHF | Synthonix | MFCD00209956 | 195.342 | C7H7BrMg | 0.000 | [Br-].[Mg+]Cc1ccccc1 | 50ml | 702445848](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695049.jpg-250.jpg)
eMolecules 1589-82-8 | Benzylmagnesium bromide, 1.0 M in 2-MeTHF | Synthonix | MFCD00209956 | 195.342 | C7H7BrMg | 0.000 | [Br-].[Mg+]Cc1ccccc1 | 50ml | 702445848
Benzylmagnesium bromide, 1.0 M in 2-MeTHF | Synthonix | 1589-82-8 | MFCD00209956 | 195.342 | C7H7BrMg | 0.000 | [Br-].[Mg+]Cc1ccccc1 | 50ml | 702445848
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