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Filtered Search Results
Apexbio Technology LLC AZD 5153(Synonyms: AZD5153, AZD-5153, AZD 5153 dihydrochloride, BRD4 inhibitor AZD5153, AZD5153 BRD4 inhibitor), 10mg, CAS: 1869912-39-9.
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AZD5153 (CAS 1869912-39-9) is a potent selective orally bioavailable inhibitor of the bromodomain and extraterminal (BET) family protein BRD4 Through simultaneous binding of both bromodomains in BRD4 AZD5153 effectively disrupts BRD4-mediated transcriptional regulation In cellular assays AZD5153 demonstrates high activity notably displacing BRD4 with an IC50 of approximately 1 7 nM in U2OS cells It significantly inhibits growth of AML multiple myeloma and diffuse large B-cell lymphoma cell lines reducing mTOR pathway signaling In vivo AZD5153 shows dose-dependent antitumor efficacy in xenograft models of hematologic malignancies indicating its value as a tool compound in cancer research
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Medchemexpress LLC Siramesine (hydrochloride) | 224177-60-0 | 99.3% | C30H32ClFN2O | 100 MG
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Siramesine hydrochloride (Lu 28-179) is a potent sigma-2 receptor agonist with subnanomolar affinity (IC50=0.12 nM) and 140-fold selectivity for sigma-2 receptors over sigma-1 receptors (IC50=17 nM). It induces cell death by destabilizing mitochondria and exhibits anti-cancer activity.
- Potent sigma-2 receptor agonist
- Displays subnanomolar affinity for sigma-2 receptors
- Induces cell death by destabilizing mitochondria
- Exhibits anti-cancer activity
- Activates caspases in HaCaT and U-87MG cells
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Medchemexpress LLC SARS-CoV-2 S protein receptor-binding domain, biotinylated (Omicron B.1.1.529) | 96.0% | 50 UG
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Recombinant biotinylated receptor-binding domain (RBD) of the SARS-CoV-2 spike protein (Omicron B.1.1.529). Produced in HEK293 cells and supplied as a filtered PBS solution, this enzymatically biotinylated RBD includes C-terminal His and Avi tags and is intended for binding assays, ELISA development, and antibody characterization.
- Expression system: HEK293 cells
- Biotinylation: site-specific Avi tag
- Formulation: 0.22 μm filtered PBS, pH 7.4
- Concentration: 0.54 mg/mL
- Purity: 96.0% by reducing SDS-PAGE
- Endotoxin: <1 EU/μg (LAL)
- Storage: store at -80°C; avoid repeated freeze-thaw
- Applications: ACE2 binding assays, ELISA, antibody characterization
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Medchemexpress LLC Olodaterol (hydrochloride) (standard) | 869477-96-3 | 99.4% | C₂₁H₂₇ClN₂O₅ | 25 MG
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Olodaterol hydrochloride is a chemical standard identified for laboratory use and substance manufacturing. It appears as a white solid with a molecular weight of 422.90 and a high purity of 99.4%.
- Suitable for laboratory research
- Used in the manufacture of substances
- White solid appearance
- High purity (99.4%)
- Consistent with structure by 1H NMR and MS
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Medchemexpress LLC Sodium naphthalen-1-yl phosphate hydrate | 207569-06-0 | MFCD00150614 | >95.0% | 286.13 g/mol | C10H9Na2O5P | 250 MG
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Sodium naphthalen-1-yl phosphate hydrate is a hydrated disodium salt of naphthyl phosphate supplied as a white to off-white solid intended for use as a biochemical reagent in life science research. It is commonly used as a substrate or reagent in enzymatic assays and organic synthesis workflows.
- appearance: white to off-white solid.
- cas number: 207569-06-0.
- molecular formula: C10H9Na2O5P (hydrated disodium salt).
- available pack sizes: 100 MG, 250 MG, 500 MG, 1 G.
- typical use: reagent or substrate in biochemical assays and research applications.
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Medchemexpress LLC Ald-Ph-PEG6-acid | 2055013-55-1 | 95.3% | 50 MG
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Ald-Ph-PEG6-acid is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker; one targets an E3 ubiquitin ligase and the other targets a protein of interest. These molecules work by harnessing the intracellular ubiquitin-proteasome system to selectively degrade target proteins. It appears as a colorless to light yellow viscous liquid.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Targets E3 ubiquitin ligase and a protein of interest
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC Amantadine hydrochloride | 665-66-7 | 98.0% | 100 MG
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Amantadine hydrochloride is an orally active and potent antiviral agent effective against influenza A viruses. It inhibits several ion channels, including NMDA and M2, as well as Coronavirus ion channels. This compound also exhibits anti-orthopoxvirus and anticancer activities.
- Effective against influenza A viruses.
- Inhibits NMDA, M2, and Coronavirus ion channels.
- Exhibits anti-orthopoxvirus activity.
- Possesses anticancer activities.
- Can be utilized for research related to Parkinson's disease.
- Useful for research on postoperative cognitive dysfunction (POCD).
- Applicable for COVID-19 research.
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Chemscene CHEMSCENE
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5000576505 S-1- NAPHTHALEN-1-YL ETHANO 5G
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eMolecules 478980-04-0 | Ambeed | Allyl(13-dimesityl-1H-imidazol-2(3H)-ylidene)palladium(IV) chloride | 100mg | 596331017 | A623132 | MFCD09039069 | 487.38 | C24H29ClN2Pd
Ambeed | (S)-4-Cyclohexyl-2-(6-(dicyclohexylmethyl)pyridin-2-yl)-45-dihydrooxazole | 100mg | 721601916 | A1519871 | | 408.630 | C27H40N2O
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Medchemexpress LLC Olodaterol hydrochloride | 869477-96-3 | >99.3% | C₂₁H₂₇ClN₂O₅ | 1 MG
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Olodaterol hydrochloride is a high-purity chemical compound primarily utilized for research and analytical studies. This compound functions as a β2-adrenergic receptor agonist and is often investigated for its potential applications in conditions such as chronic obstructive pulmonary disease (COPD) and pulmonary fibrosis. It is provided as a standard for various analytical purposes.
- Used for research and analytical studies
- Functions as a β2-adrenergic receptor agonist
- High purity verified by HPLC
- Defined chemical formula C₂₁H₂₇ClN₂O₅
- Potential relevance in chronic obstructive pulmonary disease and pulmonary fibrosis research
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Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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5000568908 BI-2865-1MG
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Medchemexpress LLC NSC 146109 hydrochloride | 59474-01-0 | MFCD09878281 | 99.9% | 316.85 | 100 MG
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NSC 146109 hydrochloride is a small-molecule p53 activator that targets MDMX and is suitable for breast cancer research. As a pseudourea derivative, it functions by activating p53 and inducing the expression of proapoptotic genes, thereby promoting apoptosis in breast cancer cells.
- Activates p53
- Targets MDMX
- Induces expression of proapoptotic genes
- Promotes apoptosis in breast cancer cells
- Pseudourea derivative
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eMolecules 869947-78-4 | 2-Amino-4-p-tolyl-thiophene-3-carboxylic acid amide | Oakwood Chemical | MFCD02854991 | 232.300 | C12H12N2OS | 0.000 | Cc1ccc(cc1)-c1csc(N)c1C(N)=O | 100mg | 537683437
2-Amino-4-p-tolyl-thiophene-3-carboxylic acid amide | Oakwood Chemical | 869947-78-4 | MFCD02854991 | 232.300 | C12H12N2OS | 0.000 | Cc1ccc(cc1)-c1csc(N)c1C(N)=O | 100mg | 537683437
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Medchemexpress LLC Tinoridine (hydrochloride) | 25913-34-2 | 100.0% | 352.88 | 25 MG
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Tinoridine hydrochloride is a nonsteroidal anti-inflammatory agent designed for research use. It demonstrates potent radical scavenger and antiperoxidative activity, reducing stable free radicals and inhibiting lipid peroxidation in rat liver microsomes. In vivo studies indicate it can significantly reduce carbon tetrachloride-induced alterations in liver enzyme activities, promoting rapid recovery.
- Potent radical scavenger and antiperoxidative activity
- Reduces stable free radicals
- Inhibits lipid peroxidation in rat liver microsomes
- Promotes rapid recovery from CCl4-induced liver enzyme alterations
- Intended for laboratory chemical use
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eMolecules 1968-40-7 | Ethyl pent-4-enoate | Ambeed | MFCD00036562 | 128.171 | C7H12O2 | 98.000 | CCOC(=O)CCC=C | 1g | 601095654
Ethyl pent-4-enoate | Ambeed | 1968-40-7 | MFCD00036562 | 128.171 | C7H12O2 | 98.000 | CCOC(=O)CCC=C | 1g | 601095654
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