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Filtered Search Results
eMolecules [3-Fluoro-4-(trifluoromethoxy)phenyl]zinc bromide, 0.5 M in THF | Synthonix |324.380 | C7H3BrF4OZn | 0.000 | [Br-].Fc1cc([Zn+])ccc1OC(F)(F)F | 50ml | 812584979
[3-Fluoro-4-(trifluoromethoxy)phenyl]zinc bromide, 0.5 M in THF | Synthonix |324.380 | C7H3BrF4OZn | 0.000 | [Br-].Fc1cc([Zn+])ccc1OC(F)(F)F | 50ml | 812584979
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 21806-61-1 | Prop-1-ene-1,3-sultone | Ambeed | MFCD12405143 | 120.120 | C3H4O3S | 98.000 | O=S1(=O)OCC=C1 | 5g | 552607691
Prop-1-ene-1,3-sultone | Ambeed | 21806-61-1 | MFCD12405143 | 120.120 | C3H4O3S | 98.000 | O=S1(=O)OCC=C1 | 5g | 552607691
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eMolecules 737797-42-1 | 4-Acetoxybutylzinc bromide, 0.50 M in THF | Synthonix260.440 | C6H11BrO2Zn | 0.000 | [Br-].CC(=O)OCCCC[Zn+] | 25ml | 627353474
4-Acetoxybutylzinc bromide, 0.50 M in THF | Synthonix | 737797-42-1260.440 | C6H11BrO2Zn | 0.000 | [Br-].CC(=O)OCCCC[Zn+] | 25ml | 627353474
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eMolecules 282727-20-2 | 2-Methoxyphenylzinc iodide, 0.50 M in THF | Synthonix | MFCD01311442 | 299.420 | C7H7IOZn | 0.000 | [I-].COc1ccccc1[Zn+] | 25ml | 627353688
2-Methoxyphenylzinc iodide, 0.50 M in THF | Synthonix | 282727-20-2 | MFCD01311442 | 299.420 | C7H7IOZn | 0.000 | [I-].COc1ccccc1[Zn+] | 25ml | 627353688
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eMolecules 1010684-05-5 | 2-Cyclohexylethylzinc bromide, 0.50 M in THF | Synthonix256.490 | C8H15BrZn | 0.000 | [Br-].[Zn+]CCC1CCCCC1 | 25ml | 703157761
2-Cyclohexylethylzinc bromide, 0.50 M in THF | Synthonix | 1010684-05-5256.490 | C8H15BrZn | 0.000 | [Br-].[Zn+]CCC1CCCCC1 | 25ml | 703157761
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eMolecules 1037176-27-4 | 3-Fluoropropylzinc iodide, 0.50 M in THF | Synthonix253.360 | C3H6FIZn | 94.000 | [I-].FCCC[Zn+] | 100ml | 627353811
3-Fluoropropylzinc iodide, 0.50 M in THF | Synthonix | 1037176-27-4253.360 | C3H6FIZn | 94.000 | [I-].FCCC[Zn+] | 100ml | 627353811
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eMolecules 737797-14-7 | 2-Fluoro-4-methylphenylzinc bromide, 0.50 M in THF | Synthonix254.410 | C7H6BrFZn | 0.000 | [Br-].Cc1ccc([Zn+])c(F)c1 | 25ml | 627353643
2-Fluoro-4-methylphenylzinc bromide, 0.50 M in THF | Synthonix | 737797-14-7254.410 | C7H6BrFZn | 0.000 | [Br-].Cc1ccc([Zn+])c(F)c1 | 25ml | 627353643
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TARGETMOL CHEMICALS INC BLU-945 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. BLU-945 is a potent highly selective reversible and orally active inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase. BLU-945 can effectively inhibit EGFR with L858R and/or exon 19 deletion mutation T790M mutation and C797S mutation. BLU-945 can be used for the research of lung cancer including non-small cell lung cancer (NSCLC). purity: 99%
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Medchemexpress LLC Crizotinib hydrochloride | 1415560-69-8 | 99.7% | C21H23Cl3FN5O | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Crizotinib hydrochloride is an orally bioavailable, selective, and ATP-competitive dual ALK and c-Met inhibitor. It also acts as a ROS proto-oncogene 1 (ROS1) inhibitor, demonstrating effective tumor growth inhibition. In cell-based assays, it inhibits tyrosine phosphorylation of NPM-ALK with an IC50 of 24 nM and tyrosine phosphorylation of c-Met with an IC50 of 11 nM.
- Inhibits ALK with an IC50 of 20 nM
- Inhibits c-Met with an IC50 of 8 nM
- Potently prevents cell proliferation, leading to G(1)-S-phase cell cycle arrest and apoptosis induction in ALK-positive ALCL cells
- Causes marked regression of large established tumors in GTL-16 model
- Significantly reduces CD31-positive endothelial cells in GTL-16 tumors
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eMolecules 62351-47-7 | 3,5-Difluorophenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | MFCD00672005 | 217.296 | C6H3BrF2Mg | 0.000 | [Br-].Fc1cc(F)cc([Mg+])c1 | 500ml | 437237116
3,5-Difluorophenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 62351-47-7 | MFCD00672005 | 217.296 | C6H3BrF2Mg | 0.000 | [Br-].Fc1cc(F)cc([Mg+])c1 | 500ml | 437237116
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Medchemexpress LLC Loperamide hydrochloride | 34552-83-5 | 99.8% | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Loperamide hydrochloride is an opioid receptor agonist and a selective and competitive human intestinal carboxylesterases (hiCE) inhibitor. It has an anti-diarrheal effect and can also induce hallmarks of ER stress and autophagy in GBM cells and MEFs.
- Opioid receptor agonist
- Selective and competitive human intestinal carboxylesterases (hiCE) inhibitor
- Anti-diarrheal effect
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eMolecules 312692-98-1 | 3,5-Dimethylphenylzinc iodide, 0.50 M in THF | Synthonix297.440 | C8H9IZn | 0.000 | [I-].Cc1cc(C)cc([Zn+])c1 | 25ml | 627353618
3,5-Dimethylphenylzinc iodide, 0.50 M in THF | Synthonix | 312692-98-1297.440 | C8H9IZn | 0.000 | [I-].Cc1cc(C)cc([Zn+])c1 | 25ml | 627353618
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Apexbio Technology LLC Empagliflozin (BI 10773) 864070-44-0 100mg
Empagliflozin (BI 10773 CAS 864070-44-0) is a potent selective inhibitor targeting sodium-glucose cotransporter 2 (SGLT-2) a transmembrane protein primarily expressed in the kidneys and responsible for glucose reabsorption Empagliflozin inhibits SGLT-2 with an IC50 of 3 1 nM demonstrating high selectivity relative to related transporters (SGLT-1 4 5 and 6) In vitro studies using HK2 human proximal tubular cells showed that empagliflozin suppresses high glucose-induced pro-inflammatory signaling pathways including TLR4 NF- B AP-1 and IL-6 secretion Empagliflozin has been widely studied in diabetic animal models such as Zucker diabetic obese rats effectively reducing blood glucose and increasing urinary glucose excretion supporting its application in diabetes research
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AdipoGen Naphthol AS-BI phosphate 2Na
Chemical. CAS 207569-04-8. Formula C18H13BrNNa2O6P . xH2O. MW 496.16 anhydrous basis. Naphthol AS-BI-phosphate is a fluorogenic substrate for acid and alkaline phosphatases. Naphthol AS-BI-phosphate is converted to naphthol AS-BI N-ASBI displaying excitation/emission spectra of 405/515nm. N-ASBI fluorescence is a quantitative marker of acid and alkaline phosphatase activity. Acid and alkaline phosphatases are often used as clinical markers of disease, since the concentration of human acid and alkaline phosphatases undergo pronounced changes in particular diseases, resulting in unusually high or low concentrations.
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eMolecules 82297-89-0 | 4-Fluoro-3-methylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | MFCD00075303 | 213.332 | C7H6BrFMg | 0.000 | [Br-].Cc1cc([Mg+])ccc1F | 100ml | 437237233
4-Fluoro-3-methylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 82297-89-0 | MFCD00075303 | 213.332 | C7H6BrFMg | 0.000 | [Br-].Cc1cc([Mg+])ccc1F | 100ml | 437237233
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