Phenanthrenes and derivatives
Apexbio Technology LLC IM-12 1129669-05-1 200mg
IM-12 (CAS 1129669-05-1) is a small-molecule inhibitor targeting glycogen synthase kinase-3 (GSK-3 ) displaying an IC50 of 53 nM GSK-3 is a serine/threonine kinase involved in neuronal development energy metabolism and Wnt/ -catenin signaling In ReNcell VM cells IM-12 inhibits GSK-3 resulting in increased -catenin accumulation enhanced TCF transcriptional activity and elevated neuronal differentiation markers The compound also extends cell doubling time and suppresses proliferation These properties make IM-12 valuable for investigating GSK-3 signaling in neurobiology cell proliferation and differentiation studies
Sigma Aldrich Fine Chemicals Biosciences Chrysene-d12 98 atom % D | 1719-03-5 | MFCD00134283 | 50MG
Chrysene-d12 98 atom % D | Purity: 99% (CP) | Mol Wt: 240.36 | 1719-03-5 | MFCD00134283 | 50MG
Selleck Chemical LLC Hypericin S3273-5mg
Hypericin (Hyp HY) is a naturally occurring substance found in the common St John s Wort (Hypericum species) with antidepressive antineoplastic and antiviral (human immunodeficiency and hepatitis C virus) activities Hypericin has inhibitory effects on MAO (monoaminoxidase) PKC (protein kinase C) dopamine-beta-hydroxylase reverse transcriptase telomerase and CYP (cytochrome P450)
Selleck Chemical LLC Malonic acid S3029-100mg
Malonic acid (MOA) one of the major dicarboxylic acids (DCAs) in aerosols has been identified experimentally and computationally to be a strong acid Malonic acid (MOA) acts as a mediate bridge for the formation of pure SA-A-based clusters
Medchemexpress LLC 6-aminochrysene | 2642-98-0 | MFCD00003699 | 99.7% | 243.30 g/mol | C18H13N | 50 MG
6-Aminochrysene is an aromatic amine research compound (CAS 2642-98-0) used in laboratory studies. The light yellow solid has molecular formula C18H13N and a molecular weight of 243.30 g/mol. The supplier lists high purity, DMSO solubility data, storage recommendations for powder and solutions, and multiple small pack sizes for research use.
- Light yellow to yellow solid appearance.
- Molecular formula C18H13N and molecular weight 243.30 g/mol.
- High purity (99.7%).
- Soluble in DMSO (100 mg/mL); sonication recommended.
- Recommended storage conditions provided for powder and in-solution forms.
- Available in small research pack sizes, including 50 mg.
Medchemexpress LLC 6-Aminochrysene | 2642-98-0 | MFCD00003699 | 99.7% | 243.30 g/mol | C18H13N | 100 MG
6-Aminochrysene is an aromatic amine used in biochemical and toxicological research. The compound is supplied as a high-purity solid or as DMSO solutions for laboratory assays and analytical studies.
- High purity of 99.7% for accurate analytical results.
- Molecular formula C18H13N and molecular weight 243.30 g/mol.
- Available in small research quantities, including 100 mg and solution formats.
- Applicable to enzymatic metabolism, mutagenicity, and toxicology studies.
- Provided with purity and identity information appropriate for research use.
AdipoGen Hypericin
Chemical. CAS 548-04-9. Formula C30H16O8. MW 504.5. Isolated from Hypericum perforatum. One of the principal active constituents of St. Johns Wort Hypericum perforatum. Hypericin is a photosensitive pigment/chromophore with bright red fluorescence emission lambdamax 594nm. Has a high triplet quantum yield and ability to produce considerable amounts of singlet oxygen and other ROS species when photoactivated. Antiviral, anticancer and antidepressant agent. Inactivates enveloped viruses including HIV. This photosensitizing agent has shown to induce apoptosis and necrosis in cancer cells during photodynamic therapy. Selective inhibitor of protein kinase C PKC. Has been shown to inhibit other kinases and targets such as EGFR-PTK, PI3K, CKII, MAPK and insulin receptor IR. Necrosis-avid contrast agent investigated for use in non-invasively targeting necrotic tissues, based on to be defined components in the phospholipid bilayer.
Apexbio Technology LLC Hypericin 548-04-9 10mg
Hypericin (CAS 548-04-9) is a small-molecule inhibitor targeting protein kinase C (PKC) and monoamine oxidase (MAO) It acts to selectively inhibit these enzymes thereby regulating cellular signal transduction pathways related to cell proliferation and apoptosis Hypericin exerts its biological activity primarily through selective inhibition of PKC In in vitro assays hypericin demonstrates an inhibitory profile with IC50 values against PKC ranging from approximately 100 to 250 nM depending on assay conditions Based on these pharmacological properties hypericin holds research potential in oncology virology and neuroscience
Medchemexpress LLC Hypericin | 548-04-9 | 98.0% | 504.44 g/mol | C30H16O8 | 10 MG
Hypericin is a photosensitive natural compound (C30H16O8) used in biochemical research as an inhibitor of protein kinase C (PKC) and monoamine oxidase (MAO). It is applied in studies of apoptosis, phototoxicity, antiviral activity, and antidepressant mechanisms, and is supplied as a solid or solution for in vitro experiments.
- Used as a PKC and MAO inhibitor in biochemical research.
- CAS number 548-04-9; molecular weight 504.44 g/mol.
- Purity typically 98.0% and appears as a brown to black solid.
- Soluble in DMSO (≈250 mg/mL with warming and ultrasonication).
- Storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years); solutions -80°C (up to 6 months).
- Available in small research quantities such as 10 MG and solution formats.
Selleck Chemical LLC Monoethyl malonic acid S3366-100mg
Monoethyl malonic acid (Ethyl hydrogen malonate Monoethyl malonate 3-Ethoxy-3-oxopropanoic acid) is the major urinary metabolites of ethyl 3-ethoxypropionate (EEP)
Chrysene 98%, Thermo Scientific™
CAS: 218-01-9 Molecular Formula: C18H12 Molecular Weight (g/mol): 228.294 InChI Key: WDECIBYCCFPHNR-UHFFFAOYSA-N Synonym: benzo a phenanthrene,1,2-benzophenanthrene,1,2-benzphenanthrene,1,2,5,6-dibenzonaphthalene,benz a phenanthrene,chrysen,rcra waste number u050,rcra waste no. u050 PubChem CID: 9171 ChEBI: CHEBI:51687 IUPAC Name: chrysene SMILES: C1=CC=C2C(=C1)C=CC3=C2C=CC4=CC=CC=C43