Phenanthrenes and derivatives
Sigma Aldrich Fullerene-C60
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich (+)-Dehydroabietylamine
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 9,10-Phenanthrenequinone
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 4,5,7-Trihydroxy-3-phenylcoumarin
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 6-Aminochrysene
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Medchemexpress LLC Bcr-Abl1-In-1 | 1488090-21-6 | 99.82% | C18H12F3N3O2 | 100 MG
BCR-ABL1-IN-1 is an inhibitor for ABL1 (64-515) with an IC50 of 8.7 nM. It can be utilized in research concerning diseases related to the central nervous system (CNS).
- Exhibits antiproliferative activity against mouse BaF3 cells expressing BCR-ABL with a GI50 of 69 nM and an IC50 of 75 nM.
- Inhibits the proliferation of Ba/F3-BCR-ABL1-WT cells with an IC50 of 30 nM.
Apexbio Technology LLC D-3-Phenyllactic acid 7326-19-4 200mg
D-3-Phenyllactic acid (CAS 7326-19-4) is a small-molecule inhibitor targeting specific Gram-positive and Gram-negative bacterial strains It is designed to disrupt microbial cell membrane integrity and interfere with related cellular metabolic pathways thereby inhibiting bacterial growth D-3-Phenyllactic acid exerts its biological activity primarily through disruption of microbial membranes and interference with cellular metabolism In in vitro studies D-3-Phenyllactic acid demonstrates inhibitory activity with reported IC50 values typically ranging between 10 50 g/mL depending on the target microorganism Based on these pharmacological properties D-3-Phenyllactic acid holds research potential in applications related to pathogen control in food safety and human health
Apexbio Technology LLC Sinapinic acid 530-59-6 200mg
Sinapinic acid (CAS 530-59-6) is an organic compound commonly utilized as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry where it facilitates the desorption and ionization of proteins and peptides for accurate molecular weight determination The compound s ability to absorb laser energy and promote analyte ionization underpins its effectiveness in proteomics research Additionally sinapinic acid is naturally occurring in propolis contributing to the compound s significance in natural product studies Its primary research applications center on biomolecular analysis and the characterization of protein mixtures
Medchemexpress LLC Azelastine hydrochloride | 79307-93-0 | 99.9% | 200 MG
Azelastine hydrochloride is an antihistamine that acts as a potent and selective histamine 1 (H1) antagonist. It is suitable for research related to allergic rhinitis, asthma, diabetic hyperlipidemia, and SARS-CoV-2. This product is for research use only.
- Potent and selective histamine 1 (H1) antagonist.
- Inhibits HNEpC proliferation, potentially aiding in airway remodeling.
- Upregulates H1R, M1R, and M3R levels in human nasal epithelial cells.
- In diabetic hyperlipidemic rat models, it significantly reduces blood glucose, HbA1c, serum alkaline phosphatase, and osteocalcin.
- Downregulates apolipoprotein B.
- Improves lipid profile (decreasing LDL-c and increasing HDL-c).
- Attenuates calcium deposition and aortic calcification.
Medchemexpress LLC Ivabradine hydrochloride | 148849-67-6 | 99.71% | 200 MG
Ivabradine hydrochloride is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). It reduces heart rate in a dose-dependent manner without affecting blood pressure.
- Potent and orally active HCN channel blocker.
- Inhibits cardiac pacemaker current (If).
- Reduces heart rate dose-dependently without modifying blood pressure.
- Exhibits anticonvulsant, anti-ischaemic, and anti-anginal activity.
- Attenuates PTZ- and PICRO-induced seizures.
- Exhibits antioxidant effects in brain areas.
- Reduces cleaved caspase-3 expression.
eMolecules Chem-Impex Malonic acid anhydrous 10kg 112444175 02873 0 000 141-82-2 104 061 C3H4O4
Chem-Impex Malonic acid anhydrous 10kg 112444175 02873 0 000 141-82-2 104 061 C3H4O4
Apexbio Technology LLC CVT-313 199986-75-9 200mg
CVT-313 (CAS 199986-75-9) is a potent inhibitor of cyclin-dependent kinase 2 (CDK2) an enzyme essential for G1/S transition during cell cycle progression By targeting CDK2 CVT-313 effectively reduces hyperphosphorylation of retinoblastoma protein (Rb) leading to cell cycle arrest at the G1/S boundary In vitro studies with MRC-5 fibroblasts demonstrated significant growth inhibition Additionally CVT-313 induces apoptosis in diffuse large B-cell lymphoma by diminishing phosphorylation of Rb at T821 and downregulating anti-apoptotic protein Mcl-1 In animal models of arterial restenosis CVT-313 significantly reduces neointimal proliferation indicating potential utility for proliferative disorders research