Phenanthrenes and derivatives
Sigma Aldrich 4-(Trifluoromethyl)cyclohexylamine
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Selleck Chemical LLC Hypericin S3273-5mg
Hypericin (Hyp HY) is a naturally occurring substance found in the common St John s Wort (Hypericum species) with antidepressive antineoplastic and antiviral (human immunodeficiency and hepatitis C virus) activities Hypericin has inhibitory effects on MAO (monoaminoxidase) PKC (protein kinase C) dopamine-beta-hydroxylase reverse transcriptase telomerase and CYP (cytochrome P450)
Apexbio Technology LLC Hypericin 548-04-9 10mg
Hypericin (CAS 548-04-9) is a small-molecule inhibitor targeting protein kinase C (PKC) and monoamine oxidase (MAO) It acts to selectively inhibit these enzymes thereby regulating cellular signal transduction pathways related to cell proliferation and apoptosis Hypericin exerts its biological activity primarily through selective inhibition of PKC In in vitro assays hypericin demonstrates an inhibitory profile with IC50 values against PKC ranging from approximately 100 to 250 nM depending on assay conditions Based on these pharmacological properties hypericin holds research potential in oncology virology and neuroscience
Selleck Chemical LLC Monoethyl malonic acid S3366-100mg
Monoethyl malonic acid (Ethyl hydrogen malonate Monoethyl malonate 3-Ethoxy-3-oxopropanoic acid) is the major urinary metabolites of ethyl 3-ethoxypropionate (EEP)
TARGETMOL CHEMICALS INC Aristolochic acid A 100MG
Also available in 1 mL, 10 mg, 25 mg, 50 mg, 500 mg and bulk. Please contact Fisher for quotes. Aristolochic acid A (TR 1736) is a compound of mutagenic, carcinogenic, and nephrotoxic compounds commonly found in the Birthwort (Aristolochiaceae) family of plants. Purity 99.97%
TARGETMOL CHEMICALS INC MALONIC ACID 500MG
Also available in 25 mg 50 mg 100 mg 1000 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Malonic acid (propanedioic acid) is the archetypal example of a competitive inhibitor it acts against succinate dehydrogenase (complex II) in the respiratory electron transport chain. Malonic acid is found to be associated with malonyl-CoA decarboxylase deficiency which is an inborn error of metabolism. purity: 98%
Cayman Chemical 4-Methylpentanoic Acid-d12, Purity: ≥99% deuterated forms (d1-d12), CAS: 116287-57-1, 50 mg
An internal standard for the quantification of 4-methylpentanoic acid by GC- or LC-MS
Cayman Chemical Aristolochic Acid, Purity: ≥98%, CAS: 313-67-7, 50 mg
A PLA2 inhibitor (IC50 = 40 µM in human neutrophils); inhibits human synovial fluid PLA2-induced edema in a dose-dependent manner in vivo; inhibits hemolytic activity of the PLA2 enzymes TFV PL-X, TFV PL-Ia, and TFV PL-Ib from T. flavoviridis venom (IC50s = 4.6, 4.0, and 3.9 µM, respectively); enhances the edema-inducing activity of TFV PL-Ia and TFV PL-Ib; associated with progressive interstitial fibrosing nephropathy and upper urinary tract urothelial carcinomas
Accela Chembio Inc Triphenylene | 25g | 217-59-4 | MFCD00001108 | 97+% | Shelf Life: 900 Days | Light Sensitive
Triphenylene | 25g | 217-59-4 | MFCD00001108 | 97+% | Shelf Life: 900 Days | Light Sensitive
Apexbio Technology LLC IM-12 1129669-05-1 200mg
IM-12 (CAS 1129669-05-1) is a small-molecule inhibitor targeting glycogen synthase kinase-3 (GSK-3 ) displaying an IC50 of 53 nM GSK-3 is a serine/threonine kinase involved in neuronal development energy metabolism and Wnt/ -catenin signaling In ReNcell VM cells IM-12 inhibits GSK-3 resulting in increased -catenin accumulation enhanced TCF transcriptional activity and elevated neuronal differentiation markers The compound also extends cell doubling time and suppresses proliferation These properties make IM-12 valuable for investigating GSK-3 signaling in neurobiology cell proliferation and differentiation studies
Apexbio Technology LLC Malonic acid 141-82-2 500mg
Malonic acid is a small-molecule dicarboxylic acid It is commonly used to facilitate the cross-linking of polysaccharide molecules such as corn starch and potato starch by forming covalent linkages via its two carboxyl groups Malonic acid acts primarily through condensation or esterification reactions to increase intermolecular connectivity and modulate the mechanical properties of biopolymer matrices Based on these properties malonic acid holds research potential in pharmaceutical excipient formulation drug delivery system development and biomaterial engineering studies
Selleck Chemical LLC Malonic acid S3029-100mg
Malonic acid (MOA) one of the major dicarboxylic acids (DCAs) in aerosols has been identified experimentally and computationally to be a strong acid Malonic acid (MOA) acts as a mediate bridge for the formation of pure SA-A-based clusters
BIOHIPPO Research Grade Anti-Human DLL3 & CD47/MER6 Biosimilar Antibody (PT-217), 100 µg
PT-217 is a research-grade biosimilar antibody targeting DLL3 CD47/MER6. It reacts with Human. Suitable for ELISA, FACS, Functional assay, Research in vivo. This research-grade biosimilar supports comparability, functional, PK/PD and immunogenicity studies. Supplied as 100 ug.