Phenanthrenes and derivatives
Medchemexpress LLC SKF 38393 hydrochloride | 62717-42-4 | MFCD00069248 | >98.0% | 291.77 g/mol | C16H18ClNO2 | 200MG
SKF 38393 hydrochloride is the hydrochloride salt of SKF-38393, a selective dopamine D1 receptor agonist with a reported IC50 of approximately 110 nM. Supplied as a research-grade solid analytical standard, it is used for in vitro pharmacology, receptor binding, and analytical assays. Not for human or clinical use.
- Selective D1 receptor agonist, reported IC50 ≈ 110 nM.
- Hydrochloride salt form improves solubility for biological assays.
- Molecular weight 291.77 g/mol.
- Chemical formula C16H18ClNO2.
- Provided as a solid analytical standard suitable for in vitro studies.
- Typical purities reported ≥98% by HPLC from third-party suppliers.
- Not for human or clinical use; for research only.
Apexbio Technology LLC IM-12 1129669-05-1 200mg
IM-12 (CAS 1129669-05-1) is a small-molecule inhibitor targeting glycogen synthase kinase-3 (GSK-3 ) displaying an IC50 of 53 nM GSK-3 is a serine/threonine kinase involved in neuronal development energy metabolism and Wnt/ -catenin signaling In ReNcell VM cells IM-12 inhibits GSK-3 resulting in increased -catenin accumulation enhanced TCF transcriptional activity and elevated neuronal differentiation markers The compound also extends cell doubling time and suppresses proliferation These properties make IM-12 valuable for investigating GSK-3 signaling in neurobiology cell proliferation and differentiation studies
Selleck Chemical LLC Malonic acid S3029-100mg
Malonic acid (MOA) one of the major dicarboxylic acids (DCAs) in aerosols has been identified experimentally and computationally to be a strong acid Malonic acid (MOA) acts as a mediate bridge for the formation of pure SA-A-based clusters
Selleck Chemical LLC Hypericin S3273-5mg
Hypericin (Hyp HY) is a naturally occurring substance found in the common St John s Wort (Hypericum species) with antidepressive antineoplastic and antiviral (human immunodeficiency and hepatitis C virus) activities Hypericin has inhibitory effects on MAO (monoaminoxidase) PKC (protein kinase C) dopamine-beta-hydroxylase reverse transcriptase telomerase and CYP (cytochrome P450)
Sigma Aldrich Fine Chemicals Biosciences Aristolochic acid I European Pharmacopoeia (EP) Reference Standard | 313-67-7 | MFCD00004996 |
Aristolochic acid I European Pharmacopoeia (EP) Reference Standard | Mol Wt: 341.27 | 313-67-7 | MFCD00004996 |
Medchemexpress LLC Dasatinib hydrochloride | 854001-07-3 | 99.3% | 524.5 g·mol⁻¹ | C22H27Cl2N7O2S | 200 MG
Dasatinib hydrochloride is a research-grade, ATP-competitive dual Src and Bcr-Abl kinase inhibitor supplied as the hydrochloride salt. It exhibits subnanomolar to low-nanomolar activity against its targets and is intended for laboratory and preclinical research applications; supplied at high purity for analytical use.
- High purity: 99.31%.
- Potent dual Src and Bcr-Abl inhibition at subnanomolar to low-nanomolar concentrations.
- Supplied as the hydrochloride salt in solid form for research use.
- Suitable for research and analytical applications; not for human consumption.
- Available in multiple pack sizes, including 200 MG.
Cayman Chemical ArIstolochIc AcId 25mg
A PLA2 inhibitor (IC50 = 40 µM in human neutrophils); inhibits human synovial fluid PLA2-induced edema in a dose-dependent manner in vivo; inhibits hemolytic activity of the PLA2 enzymes TFV PL-X, TFV PL-Ia, and TFV PL-Ib from T. flavoviridis venom (IC50s = 4.6, 4.0, and 3.9 µM, respectively); enhances the edema-inducing activity of TFV PL-Ia and TFV PL-Ib; associated with progressive interstitial fibrosing nephropathy and upper urinary tract urothelial carcinomas
Cayman Chemical ArIstolochIc AcId 50mg
A PLA2 inhibitor (IC50 = 40 µM in human neutrophils); inhibits human synovial fluid PLA2-induced edema in a dose-dependent manner in vivo; inhibits hemolytic activity of the PLA2 enzymes TFV PL-X, TFV PL-Ia, and TFV PL-Ib from T. flavoviridis venom (IC50s = 4.6, 4.0, and 3.9 µM, respectively); enhances the edema-inducing activity of TFV PL-Ia and TFV PL-Ib; associated with progressive interstitial fibrosing nephropathy and upper urinary tract urothelial carcinomas
Medchemexpress LLC Fullerene-C60 | 99685-96-8 | MFCD00151408 | 99.7% | 720.64 g/mol | C60 | 50 MG
Fullerene-C60 is a buckminsterfullerene (C60) molecular carbon compound supplied as a brown to black solid for biochemical and analytical research. It has molecular weight 720.64 g/mol and CAS 99685-96-8, and is provided at high purity for experimental use.
- High purity: 99.73%.
- Molecular formula: C60; molecular weight 720.64 g/mol.
- Physical form: brown to black solid powder.
- Low solubility: H2O < 0.1 mg/mL; DMSO < 1 mg/mL.
- Recommended storage: powder at -20°C (3 years) or 4°C (2 years).
- Suitable for biochemical assays and analytical studies.
AdipoGen Hypericin
Chemical. CAS 548-04-9. Formula C30H16O8. MW 504.5. Isolated from Hypericum perforatum. One of the principal active constituents of St. Johns Wort Hypericum perforatum. Hypericin is a photosensitive pigment/chromophore with bright red fluorescence emission lambdamax 594nm. Has a high triplet quantum yield and ability to produce considerable amounts of singlet oxygen and other ROS species when photoactivated. Antiviral, anticancer and antidepressant agent. Inactivates enveloped viruses including HIV. This photosensitizing agent has shown to induce apoptosis and necrosis in cancer cells during photodynamic therapy. Selective inhibitor of protein kinase C PKC. Has been shown to inhibit other kinases and targets such as EGFR-PTK, PI3K, CKII, MAPK and insulin receptor IR. Necrosis-avid contrast agent investigated for use in non-invasively targeting necrotic tissues, based on to be defined components in the phospholipid bilayer.