Unsaturated hydrocarbons
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Filtered Search Results
eMolecules EMOLECULES INC
5000488320 3-CYCLOPENTENE-1-OL 1G
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eMolecules EMOLECULES INC
5000491456 3-CYCLOPENTENE-1-OL 5G
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eMolecules EMOLECULES INC
5000492313 1-AMINO-3-CYCLOPENTENE HCL 5G
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Chemscene CHEMSCENE
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5000579739 2-BUTYNE-1 4-DIOIC ACID 20G
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5000579777 2-BUTYNE-1 4-DIOIC ACID 10G
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eMolecules 1,3,5,7-Tetramethyl-6-phenyl-2,4,8-trioxa-6-phosphaadamantane | 97739-46-3 | | 1g
Ambeed | 1,3,5,7-Tetramethyl-6-phenyl-2,4,8-trioxa-6-phosphaadamantane | 1g | 588342706 | A471936 | | 97739-46-3 | | 292.315 | C16H21O3P
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Medchemexpress LLC Bay 65-1942 hydrochloride | 600734-06-3 | 99.4% | C22H26ClN3O4 | 25 MG
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Bay 65-1942 hydrochloride is an ATP-competitive and selective IKKβ inhibitor, appearing as a white to off-white solid. It has demonstrated efficacy in reducing left ventricular infarct size and attenuating CK-MB levels in vitro. In vivo studies show synergistic inhibition of cell viability when combined with AZD6244, and it induces caspase 3/7 activation, making it a valuable tool for research in cancer, inflammation, and immune system diseases.
- ATP-competitive and selective IKKβ inhibitor
- White to off-white solid appearance
- Soluble in DMSO (50 mg/mL) and H2O (2.17 mg/mL)
- Inhibits IKKβ activity
- Decreases left ventricular infarct size in vitro
- Attenuates CK-MB levels in vitro
- Demonstrates synergistic inhibition of cell viability with AZD6244 in vivo
- Induces caspase 3/7 activation in vivo
- Relevant for research in cancer, inflammation, and immune system diseases
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Medchemexpress LLC Bay 65-1942 hydrochloride | 600734-06-3 | 99.39% | C22H26ClN3O4 | 2 MG
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Bay 65-1942 hydrochloride is an ATP-competitive and selective IKKβ inhibitor, intended for research use only. In vitro studies have shown that delivery of Bay 65-1942 prior to ischemia significantly decreased left ventricular infarct size and attenuated CK-MB levels compared with vehicle-treated animals. In vivo experiments demonstrated that Bay 65-1942, at a concentration of 10 μM, can synergistically inhibit cell viability and activate caspase 3/7 when combined with AZD6244 in MYL-R cells. For optimal preservation, store the solid form at 4°C in sealed conditions, away from moisture. When in solvent, store at -80°C for up to 6 months, or at -20°C for 1 month, also in sealed conditions away from moisture.
- ATP-competitive and selective IKKβ inhibitor.
- Decreases left ventricular infarct size and attenuates CK-MB levels in vitro.
- Synergistically inhibits cell viability and activates caspase 3/7 in vivo when combined with AZD6244.
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Medchemexpress LLC Cis/trans-nepetalactol | 109215-55-6 | 95.0% | 168.23 g/mol | C10H16O2 | 5 MG
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Cis/trans-nepetalactol is an iridoid natural product found in Actinidia polygama (silver vine). It is reported to be a major cat attractant and to exhibit mosquito-repellent activity. Supplied for research use, the compound is typically provided as a purified solid useful for behavioral, ecological, and chemical studies.
- Natural iridoid compound from silver vine.
- Acts as a cat attractant and insect repellent.
- Provided as a purified research-grade material (95.0% purity).
- Available in small milligram pack sizes suitable for assays.
- Useful as a reference standard or reagent in behavioral and chemical ecology studies.
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Medchemexpress LLC Bay 65-1942 hydrochloride | 600734-06-3 | 99.39% | C22H26ClN3O4 | 50 MG
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Bay 65-1942 hydrochloride is an ATP-competitive and selective IKKβ inhibitor. This chemical compound is suitable for various laboratory applications.
- ATP-competitive and selective IKKβ inhibitor
- Suitable for research use only
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Medchemexpress LLC Bpin-Cyclohexene-COOEt | 1049004-32-1 | 280.17 | 1 G
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Bpin-Cyclohexene-COOEt is a PROTAC linker belonging to the PEG class. This compound can be utilized in the synthesis of PROTAC molecules.
- PROTAC linker
- Belongs to the PEG class
- Suitable for synthesizing PROTAC molecules
- Purity of ≥97.0% by NMR
- Appears as a colorless to light yellow liquid
- Recommended storage at -20°C for 3 years (unstable in solutions, fresh preparation recommended)
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Medchemexpress LLC VE-821 | 1232410-49-9 | 99.7% | 368.41 | 50 MG
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VE-821 is a potent ATP-competitive inhibitor of ATR, with Ki/IC50 values of 13 nM/26 nM. It demonstrates excellent selectivity for ATR, showing minimal cross-reactivity against related PIKKs such as ATM, DNA-PK, mTOR, and PI3Kγ.
- Shows minimal cross-reactivity against related PIKKs ATM, DNA-PK, mTOR, and PI3Kγ
- Significantly enhances the sensitivity of PSN-1, MiaPaCa-2, and primary PancM pancreatic cancer cells to radiation and Gemcitabine
- ATR inhibition by VE-821 leads to inhibition of radiation-induced G2/M arrest in cancer cells
- Inhibits phosphorylation of Chk1 (Ser 345) in PSN-1 and MiaPaCa-2 cells after treatment with Gemcitabine, radiation, or both
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Medchemexpress LLC Bpin-Cyclohexene-COOEt, CAS [[1049004-32-1]] | 1049004-32-1 | 280.17 | 10 G
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Bpin-Cyclohexene-COOEt (Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexene-1-carboxylate) is a PROTAC linker belonging to the PEG class. It can be used to synthesize PROTAC molecules.
- PROTAC linker
- Belongs to the PEG class
- Used to synthesize PROTAC molecules
- Molecular weight: 280.17
- Purity: 97.78
- Reference compound
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Medchemexpress LLC PG-931 | 667430-81-1 | 99.8% | 1180.40 | 10 MG
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PG-931 is an analog of SHU 9119 and a potent, selective melanocortin 4 (MC4) receptor agonist. This compound has demonstrated the ability to reverse hemorrhagic shock and prevent multiple organ damage in vivo.
- Potent melanocortin 4 (MC4) receptor agonist with an IC50 of 0.58 nM.
- More selective for MC4R than for hMC3R (IC50=55 nM) or hMC5R (IC50=2.4 nM).
- Can reverse hemorrhagic shock and prevent multiple organ damage in vivo.
- Exhibits anti-shock effects at nanomolar doses.
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Medchemexpress LLC Tau protein (592-597), human TFA | 2703746-44-3 | 95.2% | 868.94 | 100 MG
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Tau protein (592-597), human TFA is a peptide fragment of human Tau protein. The dysfunction of Tau protein is involved in neurodegeneration and dementia.
- For research use only
- Solid appearance
- White to off-white color
- Sequence: Ac-Val-Gln-Ile-Ile-Asn-Lys-NH2
- Sequence shortening: Ac-VQIINK-NH2
- Solubility in H2O: ≥ 2 mg/mL (2.30 mM)
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