Acrylic acids and derivatives
Medchemexpress LLC Tbopp | 1996629-79-8 | 99.6% | 490.49 g·mol⁻¹ | C24H21F3N2O4S | 5MG
TBOPP is a selective small-molecule inhibitor of DOCK1 that binds the DOCK1 DHR-2 domain and inhibits DOCK1-mediated Rac activation. It is used in preclinical research to probe DOCK1 signaling and evaluate anti-tumor effects in cell and animal studies.
- Selective DOCK1 inhibitor with IC50 8.4 μM.
- High-affinity binding to the DHR-2 domain (Kd 7.1 μM).
- Molecular formula C24H21F3N2O4S; molecular weight 490.49 g·mol⁻¹.
- High purity (99.55%).
- Soluble in DMSO (100 mg/mL) and compatible with common in vivo formulations.
- Powder stable at -20°C for extended storage.
Medchemexpress LLC Bis-acrylate-PEG6 250mg
Bis-acrylate-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
Medchemexpress LLC 2-Acetylamino-3-(2-quinolon-4-yl)propionic acid | 681806-75-7 | 274.28 | 250 MG
2-Acetylamino-3-(2-quinolon-4-yl)propionic acid is a drug intermediate for the synthesis of various active compounds. It is for research use only and not sold to patients.
- Drug intermediate for synthesis of various active compounds.
- Available in various quantities.
- Data sheet and handling instructions available.
eMolecules Ambeed | Zanamivir | 50mg | 525024965 | A124461 | 98.000 | 139110-80-8 | MFCD00866966 | 332.313 | C12H20N4O7
Ambeed | Zanamivir | 50mg | 525024965 | A124461 | 98.000 | 139110-80-8 | MFCD00866966 | 332.313 | C12H20N4O7
![Medchemexpress LLC 2-[[[4-(Acetylamino)phenyl]sulfonyl][(4-fluorophenyl)methyl]amino]-N-(9-ethyl-9H-carbazol-3-yl)acetamide | 785821-19-4 | 98.0% | 572.65 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000403817-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2-[[[4-(Acetylamino)phenyl]sulfonyl][(4-fluorophenyl)methyl]amino]-N-(9-ethyl-9H-carbazol-3-yl)acetamide | 785821-19-4 | 98.0% | 572.65 | 5 MG
This biological molecule is sold for research purposes only and not for patient use.
- High purity of 98.0%
- Molecular weight of 572.65
- Chemical formula C31H29FN4O4S
- Appears as a solid
- Color is white to off-white
- Ships at room temperature in continental US
- Stable as powder for 3 years at -20°C or 2 years at 4°C
- Stable in solvent for 6 months at -80°C or 1 month at -20°C
Medchemexpress LLC IL-17 modulator 1 disodium | 2446803-91-2 | 98.4% | C28H35N6Na2O6P | 10MG
IL-17 modulator 1 disodium is an orally active small-molecule research compound that modulates interleukin-17 (IL-17) signaling and is used in preclinical studies of IL-17-mediated inflammatory diseases such as psoriasis, psoriatic arthritis, and ankylosing spondylitis. Supplied as a disodium salt powder with documented chemical identity and analytical data for research use only.
- Orally active small-molecule IL-17 pathway modulator.
- Disodium salt form suitable for formulation studies.
- Chemical formula C28H35N6Na2O6P and molecular weight 628.57.
- High purity (~98.4%) as provided by supplier.
- Available in small research quantities for preclinical use.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC HY-N1912 1mg Medchemexpress, Andropanolide CAS:869807-57-8 Purity:>98%
Medchemexpress, HY-N1912 1mg Andropanolide CAS:869807-57-8 Andrographolide (Andro) is a small antagonist for NF-κB activation by covalent modifying reduced cysteine 62 of p50. Andrographolide is a bicyclic diterpenoid lactone mainly produced from the plant Andrographis (Andrographis paniculate).Andrographolide suppresses the activation of NF-κB in stimulated endothelial cells, which reduces the expression of cell adhesion molecule E-selectin and prevents E-selectin-mediated leukocyte adhesion, but has no effect on IκBα degradation, p50 and p65 nuclear translocation [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 1350622-33-1 | Medchem Express | kb-NB77-78 | 5mg | 446267692 | HY-16698 | MFCD28167802 | 331.487 | C18H25NO3Si
Medchem Express | Vilazodone carboxylic acid | 10mg | 506404182 | HY-I0177 | 163521-19-5 | MFCD09833264 | 442.519 | C26H26N4O3
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eMolecules Building Block Tool<|a>
eMolecules 36840-85-4 | 1,5-Pentanediol diacrylate | Combi-Blocks | MFCD00078444 | 212.245 | C11H16O4 | 97.000 | C=CC(=O)OCCCCCOC(=O)C=C | 5g | 267203413
1,5-Pentanediol diacrylate | Combi-Blocks | 36840-85-4 | MFCD00078444 | 212.245 | C11H16O4 | 97.000 | C=CC(=O)OCCCCCOC(=O)C=C | 5g | 267203413
Medchemexpress LLC 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, 1-methylethyl ester | 59831-94-6 | 20 MG
Isopropyl ferulate is isolated from Notopterygium incisum and utilized in the reduction of pharmaceuticals, the preparation of antifungal agents, cosmetics, and as an antioxidant agent. This compound is intended for research use only.
- Isolated from natural sources.
- Can be used in pharmaceutical reduction processes.
- Suitable for the preparation of antifungal agents.
- Applicable in cosmetic formulations.
- Functions as an antioxidant agent.
- Appears as a white to off-white solid.
- Has a purity of over 99.9%.
- Store at 4°C protected from light, or at -80°C/-20°C in solvent.
Medchemexpress LLC Desacetylcinobufotalin | 4099-30-3 | 416.51 | 1 MG
Desacetylcinobufotalin is a natural compound and an apoptosis inducer. It demonstrates a marked inhibitory effect on HepG2 cells, with an IC50 value of 0.0279 μmol/mL. It is for research use only and not sold to patients. The product appears as a solid, white to light yellow in color.
- Purity: 99.41%
- Induces apoptosis
- Inhibitory effect on HepG2 cells with anIC50 of 0.0279 μmol/mL
- Cytotoxicity against human HL60 cells: IC50 4.3 μg/mL
- Cytotoxicity against human KB cells: IC50 10 μg/mL
Medchemexpress LLC HY-N0896 5mg Medchemexpress, Inulicin CAS:33627-41-7 Purity:>98%
Medchemexpress, HY-N0896 5mg Inulicin CAS:33627-41-7 Inulicin (1-O-Acetylbritannilactone) is an active compound isolated from Inula Britannica L. Inulicin (1-O-Acetylbritannilactone) inhibits VEGF-mediated activation of Src and FAK . Inulicin (1-O-Acetylbritannilactone) inhibits LPS-induced PGE 2 production and COX-2 expression, and NF-κB activation and translocation. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
AA BLOCKS LLC Ingenol mebutate | 75567-37-2 | 430.5 g/mol | 1MG
Ingenol mebutate | 75567-37-2 | 430.5 g/mol | 1MG
Medchemexpress LLC 1,4-Dicaffeoylquinic acid | 1182-34-9 | 516.45 | 5 MG
1,4-Dicaffeoylquinic acid (1,4-DCQA) is a phenylpropanoid compound isolated from Xanthii fructus. It acts as an inhibitor of xanthine oxidase with an IC50 of 7.36 μM and exhibits anti-inflammatory activity by inhibiting the production of TNF-α induced by LPS.
- Isolated from Xanthii fructus.
- Inhibitor of xanthine oxidase (IC50: 7.36 μM).
- Possesses anti-inflammatory activity.
- Inhibits the production of TNF-α induced by LPS.
- No cytotoxicity observed in RAW 264.7 cells at concentrations up to 50 μM.
- Purity: 99.25%.
Medchemexpress LLC Forsythoside I | 1177581-50-8 | 99.9% | 624.59 | C29H36O15 | 10 MG
Forsythoside I is a caffeoyl phenylethanoid glycoside used in biological research for its reported anti-inflammatory activity, including inhibition of pro-inflammatory cytokines and modulation of the TXNIP/NLRP3 inflammasome pathway.
- Used as an anti-inflammatory research compound that modulates TXNIP/NLRP3 inflammasome.
- Caffeoyl phenylethanoid glycoside; CAS number 1177581-50-8.
- Molecular formula C29H36O15 and molecular weight 624.59 g·mol⁻¹.
- High purity (99.94%) as supplied by the manufacturer.
- White to off-white solid supplied as 10 mg in a sealed vial.
- Soluble in DMSO (100 mg/mL); in vivo formulations reported include 10% DMSO with PEG300 or SBE-β-CD.
- Store solid at 4°C and protect from light; store solutions at -80°C for long term (up to 6 months) or -20°C for short term (up to 1 month).