Azobenzenes
Medchemexpress LLC Atuliflapon (AZD5718) | 2041075-86-7 | 99.0% | 25 MG
Atuliflapon (AZD5718) is a small-molecule, orally active inhibitor of 5-lipoxygenase activating protein (FLAP) used in preclinical and clinical research to modulate leukotriene biosynthesis and investigate cardiovascular inflammation.
- Inhibits FLAP with low-nanomolar potency in clinical studies.
- Demonstrates target engagement via reduced LTB4 and LTE4 biomarkers.
- Suitable for in vitro human and translational studies; species-dependent activity limits some animal models.
- Provided as a solid powder with high purity for research use.
![Medchemexpress LLC 4-N,6-N-bis[(4-fluoro-3-methylphenyl)methyl]pyrimidine-4,6-dicarboxamide | 544678-85-5 | MFCD09878513 | 99.2% | 410.42 g/mol | C22H20F2N4O2 | 1MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000238385.png-250.jpg)
Medchemexpress LLC 4-N,6-N-bis[(4-fluoro-3-methylphenyl)methyl]pyrimidine-4,6-dicarboxamide | 544678-85-5 | MFCD09878513 | 99.2% | 410.42 g/mol | C22H20F2N4O2 | 1MG
DB04760 is a potent, highly selective, non-zinc-chelating inhibitor of matrix metalloproteinase-13 (MMP-13) with a reported biochemical IC50 of 8 nM. Preclinical studies show the compound reduces paclitaxel-induced neurotoxicity and exhibits anticancer activity. The material is supplied as a light yellow to yellow solid with high purity and recommended storage conditions for powder and solution forms.
Medchemexpress LLC P32 inhibitor M36 | 802555-85-7 | MFCD31666371 | 98.6% | 448.52 g·mol-1 | C23H28N8O2 | 25MG
p32 inhibitor M36 is a small-molecule research reagent that binds directly to the mitochondrial p32 (C1QBP) protein and blocks its association with LyP-1, enabling biochemical and cell-based studies investigating p32-related pathways such as proliferation and viability.
- Binds directly to mitochondrial p32 protein.
- Inhibits p32 association with LyP-1.
- Suitable for cell-based and biochemical assays.
- High purity for research applications.
- Supplied as a solid, convenient for storage and handling.
- Molecular formula C23H28N8O2; molecular weight 448.52 g·mol-1.
eMolecules ChemScene / 4-(Diphenylamino)phenol / 100mg / 536809149 / CS-0110718 / 0.000 / 25069-86-7 / MFCD20259251 / 261.324 / C18H15NO
ChemScene / 4-(Diphenylamino)phenol / 100mg / 536809149 / CS-0110718 / 0.000 / 25069-86-7 / MFCD20259251 / 261.324 / C18H15NO
eMolecules 544678-85-5 | Medchem Express | DB04760 | 1mg | 536984011 | HY-125166 | MFCD09878513 | 410.425 | C22H20F2N4O2
Medchem Express | DB04760 | 1mg | 536984011 | HY-125166 | 544678-85-5 | MFCD09878513 | 410.425 | C22H20F2N4O2
eMolecules 78957-85-4 | Medchem Express | A-3 (hydrochloride) | 10mg | 533802412 | HY-125957 | MFCD00077311 | 321.22 | C12H14Cl2N2O2S
Medchem Express | A-3 (hydrochloride) | 10mg | 533802412 | HY-125957 | 78957-85-4 | MFCD00077311 | 321.220 | C12H14Cl2N2O2S
eMolecules 265646-85-3 | Medchem Express | Emidurdar | 5mg | 455325932 | HY-105917 | 495.183 | C16H9BrF6N6O
AstaTech | N-CYCLOPROPYL-4-(TRIFLUOROMETHYL)-BENZYLAMINE | 0.25g | 448274646 | C78379 | 97.000 | 643007-99-2 | MFCD09043527 | 215.219 | C11H12F3N
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eMolecules 844470-86-6 | ChemScene | 1-(3-Fluorophenyl)propan-1-amine hydrochloride | 100mg | 712788533 | CS-0432862 | MFCD28126471 | 189.66 | C9H13ClFN
ChemScene | 1-(3-Fluorophenyl)propan-1-amine hydrochloride | 100mg | 712788533 | CS-0432862 | 844470-86-6 | MFCD28126471 | 189.660 | C9H13ClFN
eMolecules 1215183-85-9 | ChemScene | 36-Dibromopicolinaldehyde | 100mg | 714110566 | CS-0146972 | MFCD16250664 | 264.904 | C6H3Br2NO
ChemScene | 2-Propylbenzene-13-diol | 250mg | 572195786 | CS-0128889 | 13331-19-6 | MFCD00100568 | 152.193 | C9H12O2
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eMolecules 19948-85-7 | Medchem Express | FAK-IN-7 | 5mg | 761041122 | HY-148109 | 295.36 | C16H13N3OS
Medchem Express | L-Valine-d8 | 5mg | 686240710 | HY-I1124 | 35045-72-8 | MFCD00144704 | 125.197 | C5H11NO2
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![eMolecules 31486-86-9 | Ambeed | Thieno[32-b]thiophene-2-carbaldehyde | 1g | 525077647 | A162309 | MFCD01859924 | 168.23 | C7H4OS2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502453987.PNG-250.jpg)
eMolecules 31486-86-9 | Ambeed | Thieno[32-b]thiophene-2-carbaldehyde | 1g | 525077647 | A162309 | MFCD01859924 | 168.23 | C7H4OS2
Ambeed | 3-Methyl-1H-indene | 100mg | 552730613 | A436721 | 767-60-2 | MFCD00674487 | 130.190 | C10H10
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eMolecules 947669-86-5 | Medchem Express | WWL113 | 5mg | 713704307 | HY-110148 | MFCD28160857 | 466.537 | C29H26N2O4
Medchem Express | WWL113 | 5mg | 713704307 | HY-110148 | 947669-86-5 | MFCD28160857 | 466.537 | C29H26N2O4
![Medchemexpress LLC Urea, N-[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N' | 1166393-85-6 | 98.6% | 445.52 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000387730-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Urea, N-[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N' | 1166393-85-6 | 98.6% | 445.52 | 50 MG
PF-4618433 is a potent and selective PYK2 inhibitor, with an IC50 of 637 nM. It may be suitable for the research of osteoporosis, craniofacial and appendicular skeletal defects, and for targeted bone regeneration.
- Potent and selective PYK2 inhibitor with an IC50 of 637 nM.
- Promotes osteogenesis of hMSC cultures, increasing alkaline phosphatase (ALP) activity and mineralization.
- Enhances osteoblast proliferation.
- Enhances calcium deposition.
- Increases cell proliferation activity in murine bone marrow-derived mesenchymal stem cells (BMSC).
Medchemexpress LLC FzM1.8 50mg | 2204290-85-5 | 322.31 g/mol | C18H14N2O4 | 50 MG
FzM1.8 is a small-molecule allosteric agonist of the Frizzled receptor FZD4 that activates the WNT/β-catenin signaling pathway by promoting TCF/LEF transcriptional activity in the absence of WNT ligand. The compound is provided as a research-grade, purified material with reported physicochemical and handling data suitable for in vitro and in vivo studies.
- Allosteric agonist of FZD4 that activates the WNT/β-catenin pathway.
- Suitable for in vitro and in vivo research applications.
- High reported purity (98.93%) for reproducible results.
- Molecular formula C18H14N2O4 and molecular weight 322.31 g/mol.
- Soluble in DMSO (≈83.33 mg/mL) and formulatable for in vivo dosing.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (2 years).
Medchemexpress LLC Atuliflapon (AZD5718) | 2041075-86-7 | 99.0% | 100 MG
Atuliflapon (AZD5718) is a small-molecule, orally active inhibitor of 5-lipoxygenase activating protein (FLAP) investigated as a research compound for cardiovascular indications such as coronary artery disease. It potently suppresses leukotriene production and has documented preclinical and clinical pharmacology data.
- Oral FLAP inhibitor with potent activity (reported FLAP IC50 ≈ 2 nM).
- Reduces leukotriene production in human whole blood.
- Reported molecular weight 446.50 g·mol⁻¹ and formula C24H26N6O3.
- High purity (about 99.0%), white to off-white solid.
- Soluble in DMSO (≈125 mg/mL); sonication may be required for full dissolution.
- Powder storage: -20°C for long-term stability; in solvent, store at -80°C when possible.