Azobenzenes
Methyl Red Sodium Salt, TCI America™
CAS: 845-10-3 Molecular Formula: C15H14N3NaO2 Molecular Weight (g/mol): 291.286 MDL Number: MFCD00002426 InChI Key: GNTPCYMJCJNRQB-UHFFFAOYSA-M Synonym: methyl red sodium salt,methyl red sodium,unii-311gz0qhwn,methyl purple solution,benzoic acid, 2-4-dimethylamino phenyl azo-, sodium salt,311gz0qhwn,4-dimethylaminoazobenzene-2'-carboxylic acid sodium salt,methyl red sodium salt c.i. 13020,eaetho masculinei 2,sodium methyl red PubChem CID: 4465632 IUPAC Name: sodium;2-[[4-(dimethylamino)phenyl]diazenyl]benzoate SMILES: CN(C)C1=CC=C(C=C1)N=NC2=CC=CC=C2C(=O)[O-].[Na+]
![Direct Red 80 [for Biochemical Research], TCI America™](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-2610-10-8.jpg-250.jpg)
Direct Red 80 [for Biochemical Research], TCI America™
CAS: 2610-10-8 Molecular Formula: C45H26N10Na6O21S6 Molecular Weight (g/mol): 1373.05 MDL Number: MFCD00054389 InChI Key: LDCKXVAPQFUIOI-ZFLDVXHKSA-H Synonym: hexasodium 4-hydroxy-7-5-hydroxy-7-sulfonato-6-e-2-2-sulfonato-4-e-2-4-sulfonatophenyl diazen-1-yl phenyl diazen-1-yl naphthalen-2-yl carbamoyl amino-3-e-2-2-sulfonato-4-e-2-4-sulfonatophenyl diazen-1-yl phenyl diazen-1-yl naphthalene-2-sulfonate,2-naphthalenesulfonic acid, 7,7'-carbonyldiimino bis 4-hydroxy-3-2-2-sulfo-4-2-4-sulfophenyl diazenyl phenyl diazenyl-, sodium salt 1:6,hexasodium 4-hydroxy-7-5-hydroxy-7-sulfonato-6-2-2-sulfonato-4-2-4-sulfonatophenyl diazen-1-yl phenyl diazen-1-yl naphthalen-2-yl carbamoyl amino-3-2-2-sulfonato-4-2-4-sulfonatophenyl diazen-1-yl phenyl diazen-1-yl naphthalene-2-sulfonate PubChem CID: 57369623 IUPAC Name: hexasodium;4-oxo-7-[[5-oxo-7-sulfonato-6-[[2-sulfonato-4-[(4-sulfonatophenyl)diazenyl]phenyl]hydrazinylidene]naphthalen-2-yl]carbamoylamino]-3-[[2-sulfonato-4-[(4-sulfonatophenyl)diazenyl]phenyl]hydrazinylidene]naphthalene-2-sulfonate SMILES: C1=CC(=CC=C1N=NC2=CC(=C(C=C2)NN=C3C(=CC4=C(C3=O)C=CC(=C4)NC(=O)NC5=CC6=C(C=C5)C(=O)C(=NNC7=C(C=C(C=C7)N=NC8=CC=C(C=C8)S(=O)(=O)[O-])S(=O)(=O)[O-])C(=C6)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
Thermo Scientific Chemicals 4-(4-Dimethylaminophenylazo)benzoic acid sodium salt, 97%
CAS: 845-46-5 Molecular Formula: C15H14N3NaO2 Molecular Weight (g/mol): 291.27 MDL Number: MFCD00020350 InChI Key: OSCKRHPYZNTEIO-UHFFFAOYSA-M Synonym: p-p-dimethylaminophenylazo benzoic acid sodium salt,4-4-dimethylaminophenylazo benzoic acid sodium salt,benzoic acid, 4-4-dimethylamino phenyl azo-, sodium salt,benzoic acid, p-p-dimethylamino phenyl azo-, sodium salt,benzoic acid, 4-2-4-dimethylamino phenyl diazenyl-, sodium salt 1:1,sodium 4-4-dimethylaminophenylazo benzoate,4-e-4-dimethylaminophenyl azo benzoic acid PubChem CID: 23674498 IUPAC Name: sodium;4-[[4-(dimethylamino)phenyl]diazenyl]benzoate SMILES: CN(C)C1=CC=C(C=C1)N=NC2=CC=C(C=C2)C(=O)[O-].[Na+]
Medchemexpress LLC Regaloside C | 117591-85-2 | 10 MG
Regaloside C is an anti-inflammatory agent and antioxidant that scavenges ABTS and DPPH free radicals. It targets multiple molecules, including TNF-α, MMP-2, ERα, AKT1, TLR4, and HSP90-α, making it applicable for research related to inflammatory diseases.
- Anti-inflammatory agent
- Antioxidant properties
- Scavenges ABTS and DPPH free radicals
- Targets TNF-α, MMP-2, ERα, AKT1, TLR4, and HSP90-α
- Suitable for inflammatory disease research
- Molecular weight of 416.38
- Chemical formula of C18H24O11
- Off-white to yellow solid appearance
- Originates from Gramineae Secale cereale plants
- Potent scavenger of ABTS cationic radicals (IC50 of 139.0 μM)
- Potent scavenger of DPPH anionic radicals (IC50 of 51.6 μM)
Medchemexpress LLC 2-(3-oxo-1-phenyl-3-(4-(trifluoromethyl)phenyl)propyl)malonic acid | 1221962-86-2 | 98.0% | 10 MG
PS210 is a small-molecule activator of PDK1 provided for research use. It binds the PIF-binding pocket of PDK1 and is supplied as a solid or as a 10 mM solution in DMSO for in vitro studies.
- Small-molecule PDK1 activator for research use.
- Solid and 10 mM DMSO solution formats available.
- High purity (~98.0%) confirmed by supplier analytical data.
- Molecular weight 380.31 g/mol; formula C19H15F3O5.
- Supplied in small milligram quantities suitable for biochemical assays.
Medchemexpress LLC 1-(3,4-dihydroxy-5-nitrophenyl)-2-phenylethanone | 274925-86-9 | MFCD09954136 | 99.9% | 273.24 g·mol-1 | C14H11NO5 | 10 MG
Nebicapone is a reversible catechol-O-methyltransferase (COMT) inhibitor supplied as a research-grade small molecule for preclinical pharmacology and biochemical studies. It acts mainly in the periphery to reduce conversion of L-DOPA to 3-O-methyl-DOPA and is used in experiments modeling COMT modulation and Parkinson's disease-related pathways.
- Reversible COMT inhibitor with peripheral activity.
- Reduces biotransformation of L-DOPA to 3-O-methyl-DOPA.
- Suitable for in vitro and in vivo pharmacology studies.
- Provided as solid doses (for example, 10 mg) and a 10 mM DMSO solution.
- High purity (99.89%) for research applications.
- Soluble in DMSO at ≥100 mg/mL; in vivo formulation protocols available.
- Store solid at 4°C protected from light; in solvent store at -80°C for long term or -20°C for short term.
Medchemexpress LLC 4-hydroxy-2-methyl-1,1-dioxo-N-(1,3-thiazol-2-yl)-1λ6,2-benzothiazine-3-carboxamide | 34042-85-8 | MFCD00866053 | 100.0% | 337.37 g·mol⁻1 | C13H11N3O4S2 | 10 MG
Sudoxicam is a non-steroidal anti-inflammatory drug (NSAID) of the enol-carboxamide class that acts as a reversible, orally active cyclooxygenase (COX) antagonist. Provided as a research-grade chemical for in vitro and analytical use.
- Reversible COX antagonist for inflammation research.
- Analytical-grade solid with molecular formula C13H11N3O4S2 and molecular weight 337.37 g·mol⁻¹.
- High purity (99.96%), suitable for research and analytical applications.
- Available in small package sizes (1 mg, 5 mg, 10 mg) for assay and method development.
- Storage: powder - -20°C (3 years), 4°C (2 years); in solvent - -80°C (6 months), -20°C (1 month).
Medchemexpress LLC N-cycloheptyl-6,7-dimethoxy-2-(4-piperidin-1-ylpiperidin-1-yl)quinazolin-4-amine | 864289-85-0 | 100.0% | 467.65 g/mol | C27H41N5O2 | 10 MG
C-021 is a small-molecule CCR4 antagonist (CAS 864289-85-0) provided as a high-purity solid for research use. It is intended for in vitro and in vivo pharmacology studies where CCR4 inhibition is required. Supplied quantity: 10 mg; follow recommended solvent and storage guidance when preparing solutions.
- Potent CCR4 antagonist for pharmacological research.
- High purity (99.95%).
- Solid powder form suitable for dissolution in DMSO or ethanol.
- Soluble in DMSO or ethanol at 50 mg/mL (~106.9 mM).
- Powder storage: -20°C for long-term stability; in-solution storage: -80°C recommended.
- CAS number: 864289-85-0.
![Medchemexpress LLC 2-methylsulfanyl-6-[4-[3-[3-(trifluoromethyl)anilino]-1H-1,2,4-triazol-5-yl]phenoxy]pyrimidin-4-amin | 877874-85-6 | MFCD22124522 | 99.8% | 459.45 | C20H16F3N7OS | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000287497.png-250.jpg)
Medchemexpress LLC 2-methylsulfanyl-6-[4-[3-[3-(trifluoromethyl)anilino]-1H-1,2,4-triazol-5-yl]phenoxy]pyrimidin-4-amin | 877874-85-6 | MFCD22124522 | 99.8% | 459.45 | C20H16F3N7OS | 10 MG
KG5 is an orally active small-molecule allosteric inhibitor that targets PDGFRβ and B-Raf, with additional inhibitory activity against Flt3, KIT, and c-Raf. It demonstrates anticancer and antiangiogenic effects in cellular and animal models, including inhibition of MEK/ERK signaling and suppression of tumor growth and angiogenesis in vivo.
- Orally active allosteric inhibitor of PDGFRβ and B-Raf.
- Also inhibits Flt3, KIT, and c-Raf, broadening kinase coverage.
- Demonstrated anticancer and antiangiogenic activity in vitro and in vivo.
- Disrupts MEK/ERK phosphorylation and blocks S338 phosphorylation in endothelial cells.
- Potent cellular activity with EC50 values near 0.5-0.6 μM in vascular and endothelial cells.
- High purity suitable for research applications.
- Soluble in DMSO at high concentration and formulatable for in vivo dosing.
- Stable under recommended storage conditions to preserve activity.
![Medchemexpress LLC 1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[5-(pyridin-3-yloxymethyl)-1H-pyrazol-3-yl]urea | 1166393-85-6 | MFCD25977104 | 98.6% | 445.52 g/mol | C24H27N7O2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000299294.png-250.jpg)
Medchemexpress LLC 1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[5-(pyridin-3-yloxymethyl)-1H-pyrazol-3-yl]urea | 1166393-85-6 | MFCD25977104 | 98.6% | 445.52 g/mol | C24H27N7O2 | 10 MG
PF-4618433 is a small-molecule, selective inhibitor of proline-rich tyrosine kinase 2 (PYK2) intended for research use. It exhibits an IC50 of 637 nM against PYK2 and is supplied as a high-purity solid for preclinical assays and exploratory studies in bone-related research.
- Inhibits PYK2 with a reported IC50 of 637 nM.
- High purity: 98.6%.
- Molecular weight 445.52 g/mol.
- Chemical formula C24H27N7O2.
- CAS number 1166393-85-6.
- Supplied as a 10 mg solid for laboratory research.
- Useful for osteoporosis and bone regeneration studies.
Medchemexpress LLC Ker047 (ALK2-IN-4) | 2248154-85-8 | 98.8% | 475.56 | 100 MG
Ker047 (ALK2-IN-4) is a potent activin receptor-like kinase-2 (ALK2) inhibitor. It is utilized in the research of metabolic diseases, including fibrodysplasia ossificans progressiva (FOP).
- High purity of 98.8%
- Soluble in DMSO at 10 mg/mL
- Stable as powder for up to 3 years at -20°C
- Stable in solvent for up to 2 years at -80°C
- Documentation available for data, safety, and handling
Medchemexpress LLC Oxypeucedanin hydrate | 2643-85-8 | 98.0% | 304.29 | C16H16O6 | 10 MG
Oxypeucedanin hydrate is a naturally occurring furanocoumarin isolated from D. anethifolia, supplied for laboratory research. It is provided as a small, high-purity powder suitable for analytical and biological studies.
- Natural furanocoumarin isolated from D. anethifolia.
- High purity (98.0%) suitable for analytical and biological assays.
- Small 10 mg pack size for screening and method development.
- Documented mild cytotoxicity in fibroblasts and parental lymphoma cells.
- Stable as powder when stored at -20°C (up to 3 years) or 4°C (up to 2 years).
- Solvent aliquots recommended to be stored at -80°C (up to 6 months) or -20°C (up to 1 month).
![Medchemexpress LLC 7-fluoro-6-methoxy-4-[6-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]quinol | 2248154-85-8 | MFCD32859311 | 99.4% | C26H30FN7O | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000260000.png-250.jpg)
Medchemexpress LLC 7-fluoro-6-methoxy-4-[6-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]quinol | 2248154-85-8 | MFCD32859311 | 99.4% | C26H30FN7O | 10MG
KER047 (ALK2-IN-4) is a potent small-molecule inhibitor of activin receptor-like kinase-2 (ALK2) intended for research use in the study of ALK2-mediated signaling and metabolic disorders such as fibrodysplasia ossificans progressiva (FOP). The compound is provided in solid and solution formats for in vitro and preclinical investigations.
- Potent ALK2 inhibitor with demonstrated activity in research assays.
- Suitable for research into metabolic disease models, including FOP.
- High purity (99.4%) for reproducible experimental results.
- Available as solid powder and 10 mM solutions in DMSO for flexible dosing.
- Chemical formula C26H30FN7O and molecular weight 475.56 g/mol.
- Stable storage recommendations: powder at -20°C or 4°C; in solvent at -80°C or -20°C.
Medchemexpress LLC PR5-LL-CM01, a protein arginine methyltransferase 5 (PRMT5) inhibitor | 1005307-86-7 | 98.4% | 401.51 | 1 ML
PR5-LL-CM01 is a potent protein arginine methyltransferase 5 (PRMT5) inhibitor with an IC50 of 7.5 μM. It exhibits anti-tumor activities. It has a range of IC50 at 2-4 μM in PDAC cells (PANC1, MiaPaCa2 and AsPC1) and 10-11 μM in CRC cells (HT29, HCT116 and DLD1). PR5-LL-CM01 specifically inhibits cancer cells with low toxicity in normal cells and strongly inhibits colony forming ability in PANC1 and HT29 cells. It also inhibits NF-κB activation and its target gene expression, dramatically decreasing TNFα and IL8 expression in both PANC1 and HT29 cells.
- Potent PRMT5 inhibitor.
- Exhibits anti-tumor activities.
- Low toxicity in normal cells.
- Strongly inhibits colony forming ability in PANC1 and HT29 cells.
- Inhibits NF-κB activation and its target gene expression.
- Decreases TNFα and IL8 expression.
Medchemexpress LLC PR5-LL-CM01 | 1005307-86-7 | 98.4% | 401.51 | 50 MG
PR5-LL-CM01 is a potent protein arginine methyltransferase 5 (PRMT5) inhibitor with an IC50 of 7.5 μM. It exhibits anti-tumor activities and demonstrates efficacy in inhibiting cancer cells while showing low toxicity in normal cells.
- Has IC50 values ranging from 2-4 μM in PDAC cells (PANC1, MiaPaCa2, and AsPC1) and 10-11 μM in CRC cells (HT29, HCT116, and DLD1).
- Strongly inhibits colony-forming ability in both PANC1 and HT29 cells.
- Inhibits NF-κB activation and its target gene expression in PDAC and CRC cells.
- Significantly decreases TNFα and IL8 expression in both PANC1 and HT29 cells (at 0-15 μM).
- Shows significant anti-tumor effects in PANC1 and HT29 xenografted mice in vivo (20 mg/kg; i.p.; 3 times per week) without visibly affecting their body weight.