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Phenytoin sodium is a research-grade sodium salt of 5,5-diphenylhydantoin used as an analytical standard and as a voltage-gated sodium channel inhibitor in biochemical and pharmacological studies. It is supplied in small pack sizes suitable for analytical and in vitro/in vivo formulation work.
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Phenytoin (57-41-0) is a small-molecule inhibitor targeting voltage-gated sodium channels It is designed to inhibit sodium channel activity thereby regulating neuronal excitability and electrical signaling Phenytoin exerts its biological activity primarily through the stabilization and inhibition of voltage-gated sodium channels by reducing repetitive neuronal firing In in vitro studies Phenytoin demonstrates inhibitory activity with reported IC50 values typically ranging from 40 to 60 M depending upon experimental protocols and neuronal models applied Based on these pharmacological properties Phenytoin holds research potential in neurological studies including epilepsy pathogenesis and sodium channel-targeted therapeutic mechanism evaluation
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Phenytoin (57-41-0) is a small-molecule inhibitor targeting voltage-gated sodium channels It is designed to inhibit sodium channel activity thereby regulating neuronal excitability and electrical signaling Phenytoin exerts its biological activity primarily through the stabilization and inhibition of voltage-gated sodium channels by reducing repetitive neuronal firing In in vitro studies Phenytoin demonstrates inhibitory activity with reported IC50 values typically ranging from 40 to 60 M depending upon experimental protocols and neuronal models applied Based on these pharmacological properties Phenytoin holds research potential in neurological studies including epilepsy pathogenesis and sodium channel-targeted therapeutic mechanism evaluation
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
5 5-Diphenylhydantoin sodium salt is a derivative of phenytoin. 5 5-Diphenylhydantoin is used for treating epilepsy and has antiepileptic activity. It functions by blocking the sodium channels and modulates excitation of neurons. However the side effects include hypertrichosis and overgrowth of gum tissue around the teeth. It promotes proliferation of the neural stem cells by modulating growth factors. Diphenylhydantoin is toxic and induces apoptosis in cultured cerebellar granule neurons.
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