Benzimidazoles
Fenbendazole 98.0+%, TCI America™
CAS: 43210-67-9 Molecular Formula: C15H13N3O2S Molecular Weight (g/mol): 299.348 MDL Number: MFCD00144301 InChI Key: HDDSHPAODJUKPD-UHFFFAOYSA-N Synonym: Methyl [5-(Phenylthio)benzimidazol-2-yl]carbamate, [5-(Phenylthio)benzimidazol-2-yl]carbamic Acid Methyl Ester PubChem CID: 3334 ChEBI: CHEBI:77092 IUPAC Name: methyl N-(6-phenylsulfanyl-1H-benzimidazol-2-yl)carbamate SMILES: COC(=O)NC1=NC2=C(N1)C=C(C=C2)SC3=CC=CC=C3
Albendazole 98.0+%, TCI America™
CAS: 54965-21-8 Molecular Formula: C12H15N3O2S Molecular Weight (g/mol): 265.33 MDL Number: MFCD00083232 InChI Key: HXHWSAZORRCQMX-UHFFFAOYSA-N Synonym: albendazole,albenza,eskazole,valbazen,zentel,albendazol,proftril,albendazolum,bilutac,zental PubChem CID: 2082 ChEBI: CHEBI:16664 IUPAC Name: methyl N-[6-(propylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate SMILES: CCCSC1=CC=C2N=C(NC(=O)OC)NC2=C1
Oxibendazole 98.0+%, TCI America™
CAS: 20559-55-1 Molecular Formula: C12H15N3O3 Molecular Weight (g/mol): 249.27 MDL Number: MFCD00133728 InChI Key: RAOCRURYZCVHMG-UHFFFAOYSA-N Synonym: Methyl (5-Propoxy-1H-benzo[d]imidazol-2-yl)carbamate, (5-Propoxy-1H-benzimidazol-2-yl)carbamic Acid Methyl Ester PubChem CID: 4622 IUPAC Name: methyl N-(6-propoxy-1H-benzimidazol-2-yl)carbamate SMILES: CCCOC1=CC2=C(C=C1)N=C(N2)NC(=O)OC
![Medchemexpress LLC Carbamic acid, N-[6-(phenylthio)-1H-benzimidazol-2-yl]-, methyl ester | 43210-67-9 | 99.9% | 500 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC Carbamic acid, N-[6-(phenylthio)-1H-benzimidazol-2-yl]-, methyl ester | 43210-67-9 | 99.9% | 500 MG
Fenbendazole is an orally active benzimidazole anthelmintic agent with a broad antiparasitic range. It functions as a microtubule destabilizing agent by binding to tubulin and disrupting the tubulin microtubule equilibrium. It stabilizes the transcriptional activator HIF-1α, exhibits efficient anti-proliferative activity, and induces apoptosis. This agent also causes cell-cycle arrest and mitotic cell death, demonstrating antitumor activity.
- Orally active benzimidazole anthelmintic agent
- Broad antiparasitic range
- Functions as a microtubule destabilizing agent
- Stabilizes transcriptional activator HIF-1α
- Exhibits anti-proliferative activity
- Induces apoptosis and causes cell-cycle arrest
- Demonstrates antitumor activity
Apexbio Technology LLC Omeprazole 73590-58-6 100mg
Omeprazole (73590-58-6) is a small-molecule inhibitor targeting H K -ATPase an enzyme essential for gastric acid secretion It is designed to inhibit the proton pump thereby reducing active transport of H ions into the gastric lumen Omeprazole exerts its biological activity primarily through irreversible binding to the H K -ATPase enzyme In in vitro studies Omeprazole demonstrates inhibitory activity with an IC value of approximately 5 8 M against purified H K -ATPase and an IC of 0 16 M in assays evaluating histamine-induced gastric acid production Based on these pharmacological properties Omeprazole holds research potential in the investigation of acid-mediated gastrointestinal conditions and related pathways
Apexbio Technology LLC Omeprazole 73590-58-6 10mM (in 1mL DMSO)
Omeprazole (73590-58-6) is a small-molecule inhibitor targeting H K -ATPase an enzyme essential for gastric acid secretion It is designed to inhibit the proton pump thereby reducing active transport of H ions into the gastric lumen Omeprazole exerts its biological activity primarily through irreversible binding to the H K -ATPase enzyme In in vitro studies Omeprazole demonstrates inhibitory activity with an IC value of approximately 5 8 M against purified H K -ATPase and an IC of 0 16 M in assays evaluating histamine-induced gastric acid production Based on these pharmacological properties Omeprazole holds research potential in the investigation of acid-mediated gastrointestinal conditions and related pathways
Sigma Aldrich Fine Chemicals Biosciences Omeprazole solid500MG
Omeprazole is a benzimidazole derivative a weak base and is lipophilic in nature. This compound is pH sensitive and does not exists in its original form at low pH.
Medchemexpress LLC (R)-Omeprazole (sodium) | 161796-77-6 | 98.1% | 25 MG
(R)-Omeprazole sodium is a gastric acid resistant compound that inhibits gastric acid secretion. It is metabolized in vivo, primarily by cytochrome P450 enzymes, and its interaction with mannitol may affect its bioavailability in formulations. It exhibits reversible direct and metabolism-dependent inhibition of CYP2C19.
- Gastric acid resistant compound
- Inhibits gastric acid secretion
- Metabolized by cytochrome P450 enzymes
- Reversible direct and metabolism-dependent inhibition of CYP2C19
- For research use only
Medchemexpress LLC (R)-Omeprazole sodium | 161796-77-6 | 98.1% | 100 MG
(R)-Omeprazole sodium is a gastric acid resistant compound that inhibits gastric acid secretion. It is primarily metabolized by cytochrome P450 enzymes in vivo, and its interaction with mannitol may affect its bioavailability in formulations. This compound exhibits reversible direct and metabolism-dependent inhibition of CYP2C19. It is intended for research use only.
- Gastric acid resistant compound
- Inhibits gastric acid secretion
- Metabolism affected by cytochrome P450 enzymes
- May interact with mannitol affecting bioavailability
- Exhibits reversible direct and metabolism-dependent inhibition of CYP2C19
- For research use only
Medchemexpress LLC (R)-Omeprazole sodium | 161796-77-6 | 98.1% | 50 MG
(R)-Omeprazole sodium is a gastric acid resistant compound that inhibits gastric acid secretion. Its metabolism in vivo is primarily affected by cytochrome P450 enzymes. The interaction between (R)-Omeprazole sodium and mannitol may affect its bioavailability in formulations. It exhibits reversible direct and metabolism-dependent inhibition of CYP2C19.
- Gastric acid resistant compound
- Inhibits gastric acid secretion
- Metabolized primarily by cytochrome P450 enzymes
- Interaction with mannitol may affect bioavailability
- Exhibits reversible direct and metabolism-dependent inhibition of CYP2C19
Medchemexpress LLC (R)-Omeprazole (sodium) | 161796-77-6 | 98.1% | 250 MG
(R)-Omeprazole sodium is a gastric acid resistant compound that inhibits gastric acid secretion. It is primarily metabolized in vivo by cytochrome P450 enzymes. Interactions with mannitol may affect its bioavailability in certain formulations.
- Inhibits gastric acid secretion
- Metabolized by cytochrome P450 enzymes
- Interacts with mannitol
- Reversibly inhibits CYP2C19 directly and metabolism-dependently
- For research use only
Apexbio Technology LLC Albendazole 54965-21-8 10mM (in 1mL DMSO)
Albendazole (CAS 54965-21-8) is a small-molecule inhibitor targeting tubulin It is designed to disrupt microtubule assembly thereby impairing cellular cytoskeletal function and parasite viability Albendazole exerts its biological activity primarily through binding to tubulin and inhibiting microtubule polymerization In tumor cell-based assays Albendazole demonstrates antiproliferative activity and induces cell cycle arrest autophagy and apoptosis with reported IC50 values typically ranging from 0 1 to 1 M depending on cell line and experimental conditions Based on these pharmacological properties Albendazole holds research potential in studies of parasitic infections microtubule dynamics tumor cell proliferation angiogenesis and programmed cell death
Apexbio Technology LLC Albendazole 54965-21-8 100mg
Albendazole (CAS 54965-21-8) is a small-molecule inhibitor targeting tubulin It is designed to disrupt microtubule assembly thereby impairing cellular cytoskeletal function and parasite viability Albendazole exerts its biological activity primarily through binding to tubulin and inhibiting microtubule polymerization In tumor cell-based assays Albendazole demonstrates antiproliferative activity and induces cell cycle arrest autophagy and apoptosis with reported IC50 values typically ranging from 0 1 to 1 M depending on cell line and experimental conditions Based on these pharmacological properties Albendazole holds research potential in studies of parasitic infections microtubule dynamics tumor cell proliferation angiogenesis and programmed cell death
Medchemexpress LLC Omeprazole | 73590-58-6 | 100.0% | C17H19N3O3S | 500 MG
Omeprazole is a proton pump inhibitor (PPI) used to treat acid-related gastrointestinal disorders. It works by competitively inhibiting CYP2C19 activity. Additionally, Omeprazole inhibits the growth of Gram-positive and Gram-negative bacteria and is identified as a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor. This acid-labile compound is used in the treatment of various conditions including dyspepsia, peptic ulcer disease, and gastroesophageal reflux disease.
- Proton pump inhibitor
- Competitively inhibits CYP2C19 activity (Ki of 2 to 6 μM)
- Inhibits growth of Gram-positive and Gram-negative bacteria
- Potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor
- Inhibits gastric acid secretion
- Used for treating acid-related gastrointestinal disorders
Medchemexpress LLC Omeprazole | 73590-58-6 | 99.9% | 345.42 | 100 MG
Omeprazole is a proton pump inhibitor (PPI) used for treating acid-related gastrointestinal disorders. It competitively inhibits CYP2C19 activity and inhibits the growth of both Gram-positive and Gram-negative bacteria. Additionally, it is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor and an exosome inhibitor.
- Proton pump inhibitor (PPI)
- Competitively inhibits CYP2C19 activity
- Inhibits growth of Gram-positive and Gram-negative bacteria
- Potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor
- Exosome inhibitor
- Inhibits gastric acid secretion
- Acid-labile compound