Biotin and derivatives
Medchemexpress LLC Biotin-PEG8-NHS ester | 2143968-03-8 | MFCD27977502 | 99.9% | C33H56N4O14S | 10MG
Biotin-PEG8-NHS ester is a PEG-based heterobifunctional linker that combines a biotin affinity tag with an N-hydroxysuccinimide (NHS) ester to enable efficient conjugation to primary amines. It is suitable for biotinylation of peptides, proteins, and small molecules, and for use as a linker in targeted protein degradation research and affinity capture workflows.
- Enables efficient conjugation to primary amines via NHS ester chemistry.
- Provides a biotin tag for streptavidin-based capture and detection.
- PEG8 spacer improves solubility and reduces steric hindrance.
- High purity for reproducible conjugation and downstream analysis.
- Suitable for synthesis of linkers and bioconjugates in research applications.
Chem-Impex International, Inc. (+) Biotinyl-6-aminohexanoic acid | 72040-64-3 | MFCD00144853 | 250MG
(+) Biotinyl-6-aminohexanoic acid, 72040-64-3, MFCD00144853, 250MG
Medchemexpress LLC DOTA-NHS-ester | 170908-81-3 | MFCD23381190 | >97.0% | 501.49 g/mol | C20H31N5O10 | 50 MG
DOTA-NHS-ester is an activated N-hydroxysuccinimide (NHS) ester of the DOTA chelator used to conjugate DOTA to amine-containing molecules for radiolabeling and imaging applications. It is intended for research use and is typically used to prepare peptide or antibody conjugates for small-animal PET, SPECT, and CT studies.
- Activated NHS-ester for amine conjugation.
- Used to prepare conjugates for PET, SPECT, and CT imaging.
- Suitable for labeling radiotherapeutic agents and imaging probes.
- Molecular weight approximately 501.49 g/mol.
- Stored sealed and away from moisture; in solvent: -80°C for 6 months, -20°C for 1 month.
Medchemexpress LLC Rhodamine B NHS ester | 144700-55-0 | 96.9% | 576.08 | C32H34ClN3O5 | 10 MG
Rhodamine B NHS ester is an N-hydroxysuccinimide (NHS) activated fluorescent dye for covalent labeling of primary amines in proteins, peptides, and other biomolecules. It forms stable amide bonds to introduce a rhodamine fluorophore for fluorescence microscopy, flow cytometry, and biochemical assays.
- NHS-activated for efficient and selective amine coupling.
- Bright rhodamine fluorescence suitable for microscopy and flow cytometry.
- Molecular weight 576.08 g/mol and formula C32H34ClN3O5.
- High purity (~96.9%) for reliable labeling performance.
- Available in small research pack sizes for convenient use.
Medchemexpress LLC Biotin-PEG8-NHS ester | 2143968-03-8 | 99.89% | C33H56N4O14S | 100 MG
Biotin-PEG8-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins by linking a ligand for an E3 ubiquitin ligase and a ligand for the target protein.
- For research use only
- Available in various quantities
- Multiple documentation types available
- White to off-white solid appearance
Medchemexpress LLC Biotin-Ahx-angiotensin II (human) | 115102-72-2 | 100.0% | C66H96N16O15S | 10MG
Biotin-Ahx-Angiotensin II (human) is a biotinylated octapeptide derived from angiotensin II, provided as a lyophilized powder for use as an affinity probe in biochemical and receptor-binding assays. The biotin tag attached via an aminohexanoic acid (Ahx) spacer enables streptavidin-based capture or detection while maintaining the peptide's biological activity. Molecular formula C66H96N16O15S; molecular weight 1385.63.
- Biotin tag for streptavidin-based detection and capture.
- Ahx spacer reduces steric hindrance and preserves peptide activity.
- Sequence corresponds to human angiotensin II for biologically relevant assays.
- High purity for consistent and reproducible results.
- Lyophilized powder format for long-term storage and easy reconstitution.
Medchemexpress LLC FP-biotin | 259270-28-5 | 99.8% | C27H50FN4O5PS | 10MG
FP-Biotin is a biotinylated fluorophosphonate probe designed to covalently label serine hydrolases for activity-based profiling. The biotin tag enables enrichment and identification of labeled proteins or peptides from plasma and complex samples using avidin/streptavidin capture. Available as a solid and as a DMSO solution for flexible workflows.
- covalently labels serine hydrolases for activity profiling
- enables affinity purification via biotin-avidin interaction
- suitable for plasma and complex biological samples
- supplied as solid or ready-to-use solution for workflow flexibility
- high purity for reproducible results
- supported by data sheet, COA, and SDS for quality and safety
Medchemexpress LLC Biotin-peg-biotin | 194920-55-3 | 99.3% | C26H44N6O6S2 | 100 MG
Biotin-PEG-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC M-PEG-NHS ester (MW 10000) | 92451-01-9 | 98.0% | Poly(oxy-1,2-ethanediyl), α-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-ω-methoxy- | 25 MG
m-PEG-NHS ester (MW 10000) is a PEG-based PROTAC linker. It is for research use only and not sold to patients. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. These compounds contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Composed of PEG, alkyl, and ether groups
Medchemexpress LLC Biotin-Gastrin Releasing Peptide, human TFA | 3085.67 | 10 MG
Biotin-Gastrin Releasing Peptide, human TFA is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties.
- Molecular weight: 3085.67
- Chemical formula: C140H218N40O33S3.xC2HF3O2
- Appearance: Solid
- Soluble in DMSO at 100 mg/mL
- Shipping: Room temperature
- Storage (powder): -80°C for 2 years, -20°C for 1 year
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
eMolecules 1688598-83-5 | NHS-PEG1-SS-PEG1-NHS | Medchem Express436.410 | C14H16N2O10S2 | 98.000 | O=C(OCCSSCCOC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 100mg | 816503954
NHS-PEG1-SS-PEG1-NHS | Medchem Express | 1688598-83-5436.410 | C14H16N2O10S2 | 98.000 | O=C(OCCSSCCOC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 100mg | 816503954
eMolecules 1807518-72-4 | Mal-PEG1-NHS ester | Medchem Express | MFCD26127783 | 310.262 | C13H14N2O7 | 98.000 | O=C(CCOCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 10mg | 795391586
Mal-PEG1-NHS ester | Medchem Express | 1807518-72-4 | MFCD26127783 | 310.262 | C13H14N2O7 | 98.000 | O=C(CCOCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 10mg | 795391586
Medchemexpress LLC Biotin LC hydrazide | 109276-34-8 | MFCD00077659 | 99.8% | 371.50 g/mol | C16H29N5O3S | 50 MG
Biotin LC hydrazide is a long-chain hydrazide reagent used to introduce a biotin tag onto periodate-oxidized glycans and glycoproteins. It labels aldehyde groups created by mild oxidation, delivering a biotin tag with an extended spacer arm that improves accessibility for detection and capture in downstream assays.
- Reacts with periodate-oxidized glycoproteins and carbohydrate aldehydes.
- Provides an extended spacer arm for improved streptavidin accessibility.
- Suitable for biotinylation of proteins, glycans, and nucleic acids.
- High purity suitable for analytical and preparative applications.
- Provided as a solid in small, research-scale quantities.
Medchemexpress LLC Biotin-PEG2-NHS ester | 596820-83-6 | 96.7% | C21H32N4O8S | 25 MG
Biotin-PEG2-NHS ester is a biotin-labeled, PEG-based PROTAC linker. It can be used in the synthesis of PROTACs, which contain two different ligands connected by a linker. One ligand is for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Biotin-labeled
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- One ligand is for an E3 ubiquitin ligase
- Other ligand is for the target protein
- PROTACs exploit the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins