Biotin and derivatives
Medchemexpress LLC Bis-PEG6-NHS ester | 1526718-98-8 | 576.55 g/mol | C24H36N2O14 | 1 G
Bis-PEG6-NHS ester is a PEG-based bifunctional linker containing two N-hydroxysuccinimide (NHS) ester reactive groups separated by a six-unit polyethylene glycol spacer. It is used for conjugation to primary amines and as a linker in PROTAC and cleavable ADC synthesis.
- Provides two NHS ester reactive groups for amine coupling.
- PEG6 spacer improves solubility and flexibility.
- Suitable for PROTAC and ADC linker synthesis.
- Molecular weight 576.55 g/mol and formula C24H36N2O14.
- Available in multiple pack sizes including 1 g.
Medchemexpress LLC Nsp-dmae-nhs | 194357-64-7 | 99.5% | 1 MG
NSP-DMAE-NHS is an acridinium ester chemiluminescence reagent containing an N-sulfopropyl group. It is useful in the clinical diagnostics industry, especially in automated immunochemistry analyzers. The product is for research use only and not sold to patients.
- Acridinium ester chemiluminescence reagent
- Contains n-sulfopropyl group
- Useful in the clinical diagnostics industry
- Applicable in automated immunochemistry analyzers
Apexbio Technology LLC Sulfo-NHS-Biotin Kit (90-180 kDa) 3samples
Sulfo-NHS-Biotin labeling is widely utilized in biochemical research to covalently conjugate biotin molecules to free amino groups on protein molecules primarily lysine residues and N-terminal amines The reaction proceeds via activated ester intermediates forming stable amide bonds that facilitate subsequent detection or purification using streptavidin-biotin affinity interactions This labeling method is routinely applied to diverse protein samples particularly immunoglobulin G and other antibodies (molecular weight 90-180 kDa) enabling downstream applications such as immunoassays Western blotting immunoprecipitation and flow cytometry analyses Commonly the labeled proteins are purified rapidly by spin-based filtration to eliminate unreacted small molecules improving purity and yield
Sigma Aldrich Fine Chemicals Biosciences Biotin disulfide N-hydroxysuccinimide ester >98%, powder | Purity: >98% | Mol Wt: 575.72 | 142439-92-7 | MFCD00466919 | 100MG
Biotin disulfide N-hydroxysuccinimide ester >98%, powder | Purity: >98% | Mol Wt: 575.72 | 142439-92-7 | MFCD00466919 | 100MG
Medchemexpress LLC Bz-(Me)Tz-NHS | 1454558-58-7 | 95.0% | 412.40 g/mol | C19H20N6O5 | 10 MG
Bz-(Me)Tz-NHS is a methyltetrazine-containing N-hydroxysuccinimide (NHS) ester used as a bioorthogonal linker for copper-free click chemistry. It undergoes rapid inverse electron-demand Diels-Alder (iEDDA) reactions with strained alkenes to enable fast, selective conjugation under mild, biocompatible conditions. The reagent is supplied as a purple solid with high purity and requires sealed, low-temperature storage to maintain stability.
- Methyltetrazine-containing NHS ester enabling copper-free inverse electron-demand Diels-Alder conjugation.
- Rapid reaction kinetics with strained alkenes for efficient labeling.
- NHS ester functional group for covalent coupling to primary amines.
- High purity suitable for bioconjugation workflows.
- Purple solid appearance for easy visual identification.
- Stable when stored sealed at 4°C; in solvent store at -80°C for long-term preservation.
Medchemexpress LLC Sulfo-Cyanine7 NHS ester potassium | 1603861-95-5 | 90.0% | 10 MG
Sulfo-Cyanine7 NHS ester potassium is a water-soluble, amine-reactive N-hydroxysuccinimide (NHS) ester of a near-infrared cyanine dye supplied as the potassium salt. It is used to label primary amines on proteins, peptides, and other biomolecules to produce sulfo-Cyanine7-labeled conjugates for near-IR fluorescence imaging and related research applications.
- Water-soluble near-infrared fluorescent dye.
- Amine-reactive NHS ester for efficient conjugation to proteins.
- Supplied as the potassium salt for enhanced solubility.
- Suitable for labeling proteins, peptides, and other biomolecules.
- Produces stable, near-IR fluorescent conjugates for imaging applications.
Medchemexpress LLC Biotin-PEG7-maleimide | 1898221-65-2 | 99.4% | 745.88 g/mol | C33H55N5O12S | 25 MG
Biotin-PEG7-maleimide is a thiol-specific biotinylation reagent that introduces a biotin tag through a PEG7 spacer by reacting with free thiol (-SH) groups. It is used for selective cysteine labeling, affinity capture and detection, and for constructing drug-linker conjugates in bioconjugation workflows.
- Thiol-reactive maleimide group for selective cysteine labeling.
- PEG7 spacer provides flexibility and improved solubility.
- Biotin tag enables affinity capture and detection.
- High purity (99.4%) suitable for sensitive assays.
- Powder stable at -20°C for up to 3 years.
- Available as 25 MG quantity.
Medchemexpress LLC Mal-PEG8-NHS ester | 2055033-05-9 | 99.0% | 250 MG
Mal-PEG8-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) are molecules that harness the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Consists of two different ligands connected by a linker
- One ligand for an E3 ubiquitin ligase
- Other ligand for the target protein
Medchemexpress LLC Biotin-PEG11-amine | 1418022-42-0 | 99.85% | C34H66N4O13S | 50 MG
Biotin-PEG11-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. It is for research use only.
- Biotin-labeled
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Apexbio Technology LLC Biotin-11-dUTP(Synonyms: Biotin-11-deoxyuridine triphosphate, Biotin-11-dUTP lithium salt), 200ul (5 mM), CAS: 1221498-88-9.
Biotin-11-dUTP (CAS 1221498-88-9) is a biotin-conjugated analogue of deoxythymidine triphosphate (dTTP) that can be incorporated enzymatically into DNA or cDNA sequences during polymerase reactions After integration labeled nucleic acid fragments can be detected using streptavidin coupled to horseradish peroxidase (HRP) alkaline phosphatase (AP) fluorescent molecules or bead-based capture systems This approach is frequently utilized in polymerase chain reaction (PCR) nick translation reverse transcription assays and apoptosis studies facilitating DNA probe labeling and molecular analysis workflows
Medchemexpress LLC Azido-PEG8-NHS ester | 1204834-00-3 | MFCD13184949 | 99.5% | 564.58 | C23H40N4O12 | 1 G
Azido-PEG8-NHS ester is an azide-functional polyethylene glycol (PEG) linker bearing an N-hydroxysuccinimide (NHS) ester reactive group used for amine bioconjugation and click chemistry in ADC and PROTAC linker synthesis.
- Enables NHS-amine coupling to primary amines.
- Azide group enables copper-catalyzed and strain-promoted click chemistry.
- PEG8 spacer increases solubility and reduces steric hindrance.
- High reported purity for reliable conjugation performance.
- Available in small laboratory pack suitable for research-scale work.
eMolecules 1353016-71-3 | DBCO-NHS ester | Chem-Impex | MFCD24386367 | 402.406 | C23H18N2O5 | 97.000 | O=C(CCC(=O)N1Cc2ccccc2C#Cc2ccccc12)ON1C(=O)CCC1=O | 25mg | 490843458
DBCO-NHS ester | Chem-Impex | 1353016-71-3 | MFCD24386367 | 402.406 | C23H18N2O5 | 97.000 | O=C(CCC(=O)N1Cc2ccccc2C#Cc2ccccc12)ON1C(=O)CCC1=O | 25mg | 490843458
Medchemexpress LLC Biotin (Standard) | 58-85-5 | 99.8% | 50 MG
Biotin (Standard) is the analytical standard of Biotin, also known as vitamin B7. It serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids.
- Analytical standard grade
- Reference standard for assay
- Used in qualitative research experiments
- Used in quantitative research experiments
- Used in methodological research experiments
- Suitable for HPLC applications
- Suitable for GC applications
- Suitable for MS applications
- Essential for cell growth
- Essential for fatty acid production
- Essential for metabolism of fats and amino acids