Biotin and derivatives
Biotium CF790 Free Acid
Near-IR CF dye free acids are control dyes for studies that involve CF dye succinimidyl ester conjugated to antibody, protein or peptides. CF dyes are Biotium's line of next-generation fluorescent dyes with advantages in brightness, photostability, and conjugate specificity compared to other fluorescent dyes. Near-infrared fluorescent CF790 dye has excitation/emission at 784/806 nm.
Medchemexpress LLC M-PEG-NHS ester | 92451-01-9 | 98.0% | (C2H4O)nC7H9NO5 | 50 MG
M-PEG-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Peg-based protac linker
- Used in the synthesis of protacs
- Protacs contain two different ligands connected by a linker
- Features a ligand for an E3 ubiquitin ligase and another for the target protein
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Apexbio Technology LLC Biotin Hydrazide 66640-86-6 500mg
Biotin hydrazide is a hydrazide-functionalized biotin derivative designed to selectively label and detect protein carbonylation an irreversible post-translational modification frequently arising from oxidative stress conditions Protein carbonylation typically results from reactions between protein side chains and reactive oxygen species (ROS) lipid peroxidation metabolites such as -unsaturated -hydroxyalkenals or glycation-mediated oxidative modifications Mechanistically Biotin Hydrazide interacts specifically with protein-bound carbonyl groups through hydrazone formation under mildly acidic conditions (around pH 5 5) without the requirement of additional reducing agents or catalysts Thus Biotin hydrazide facilitates biochemical studies aimed at identifying and characterizing carbonyl-modified proteins in biological samples through biotin-based detection assays and downstream proteomic analysis techniques
Chem-Impex International, Inc. Biotin-N-hydroxysuccinimide | 35013-72-0 | MFCD00078531 | 5G
Biotin-N-hydroxysuccinimide, 35013-72-0, MFCD00078531, 5G
Medchemexpress LLC Bis-PEG9-NHS ester 5g | 1008402-79-6 | 708.71 | C30H48N2O17 | 5 G
Bis-PEG9-NHS ester is a homobifunctional PEG-based linker bearing two N-hydroxysuccinimide (NHS) ester reactive groups, used to conjugate primary amines on proteins, peptides, and small molecules for research applications.
- Homobifunctional PEG9 spacer with two NHS ester reactive groups.
- Facilitates amine-directed bioconjugation to proteins and peptides.
- Hydrophilic PEG spacer improves solubility in aqueous media.
- Suitable for PROTAC and ADC linker chemistry in research.
- High purity for reliable experimental performance.
Medchemexpress LLC Biotin-PEG6-NHS ester | 2055045-04-8 | 98.0% | C29H48N4O12S | 25 MG
Biotin-PEG6-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Enables targeted protein degradation via the ubiquitin-proteasome system
- Connects ligands for E3 ubiquitin ligase and target proteins
TARGETMOL CHEMICALS INC NSP-SA-NHS 5MG
Also available in 1 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. NSP-SA-NHS is a chemiluminescent acridinium ester that can be used for immunoassays. Purity 98.42%
Chem-Impex International, Inc. (+)-Biotinamidocaproyl hydrazide | MFCD00077659 | 50MG
(+)-Biotinamidocaproyl hydrazide, MFCD00077659, 50MG
Medchemexpress LLC M-PEG14-NHS ester | 00-00-0 | 95.0% | 773.86 g/mol | C34H63NO18 | 5 MG
m-PEG14-NHS ester is a methoxy-terminated polyethylene glycol linker bearing an N-hydroxysuccinimide (NHS) ester functional group. It is designed for amine-reactive conjugation in the synthesis of proteolysis targeting chimeras (PROTACs) and related bioconjugation workflows, supplied as a white to off-white solid for research use only.
- Provides an m-PEG14 spacer for flexible linker length
- NHS ester enables efficient coupling to primary amines
- High purity suitable for synthetic applications
- Offered in small quantities for laboratory-scale synthesis
- Stable when stored sealed at low temperature and protected from moisture
Medchemexpress LLC IL-12 Human Biotin 100ug | 100ug
IL-35 protein plays a key role in immune regulation forming IL-12 cytokine with IL12B or IL-35 cytokine with EBI3/IL27B IL-12 modulates T cell and natural killer cell responses and induces interferon gamma production IL-12 Protein Human (Biotinylated HEK293 His-Avi) is a recombinant protein dimer complex containing human-derived IL-12 protein expressed by HEK293 with C-Avi C-His labeled tag IL-12 Protein Human (Biotinylated HEK293 His-Avi) has molecular weight of 40-45 kDa
Medchemexpress LLC Peptidyl arginine deiminase 4, human (biotinylated, His-tagged) | >95.0% | 20UG
Recombinant full-length human peptidyl arginine deiminase 4 (PADI4), biotinylated and N-terminal His-tagged, supplied as a 20 μg solution formulated in 20 mM Tris, 500 mM NaCl, 0.5 mM TCEP, 1 mM EDTA, 10% glycerol, pH 7.6. Intended for biochemical assays, affinity capture, and binding studies using biotin-streptavidin or His-tag detection.
- Full-length sequence (M1-P663)
- Biotinylated for streptavidin-based capture and detection
- N-terminal His tag for purification and detection
- Greater than 95.0% purity by reducing SDS-PAGE
- Molecular weight approximately 76.6 kDa
- Expressed in Escherichia coli
- Formulated in stabilizing buffer (Tris, NaCl, TCEP, EDTA, glycerol)
- Supplied as 20 μg aliquot, recommended storage at -80 °C
Sigma Aldrich Fine Chemicals Biosciences Biotin | 58-85-5 | MFCD00005541 | 5g
Biotin | Purity: 99% | Mol Wt: 244.31 | 58-85-5 | MFCD00005541 | 5g
Chem-Impex International, Inc. Biotinyl-e-aminocaproic acid-N-hydroxysuccinimide ester | 72040-63-2 | MFCD00065502 | 1G
Biotinyl-e-aminocaproic acid-N-hydroxysuccinimide ester, 72040-63-2, MFCD00065502, 1G
IBA LifeSciences Biotin powder; 5 g
Biotin is a water-soluble B-complex vitamin, also known as vitamin B7 or vitamin H. It binds to the biotin-binding pockets of streptavidin, Strep-Tactin, and Strep-TactinXT with different affinities. As a result, it allows the efficient elution of Strep-tagII or Twin-Strep-tag fusion proteins from Strep-TactinXT, while maintaining the reusability of the resin. It can be used for preparation of Strep-TactinXT elution buffer, Buffer BXT. In addition, biotin can be used for elution of biotinylated proteins from Strep-Tactin, where it binds irreversibly to the resin. Hence, Strep-Tactin cannot be regenerated in this kind of application.