Furans
Medchemexpress LLC Fluticasone furoate | 397864-44-7 | C27H29F3O6S | 500 MG
Fluticasone furoate is a topical, intranasal, enhanced-affinity synthetic trifluorinated corticosteroid with a Kd of 0.3 nM. It exhibits potent anti-inflammatory and anti-asthmatic activity with low systemic exposure and has potential for treating allergic rhinitis.
- Potent anti-inflammatory and anti-asthmatic activity
- Low systemic exposure
- Potential for treating allergic rhinitis
- Available as a nasal spray for topical administration
- High potency in inhibiting tumor necrosis factor synthesis and action
- Effective in preventing damage to cultured human lung epithelial cells
Apexbio Technology LLC Mometasone furoate 83919-23-7 10mM (in 1mL DMSO)
Mometasone furoate (83919-23-7) is a glucocorticoid receptor agonist targeting intracellular glucocorticoid receptors It is designed to modulate glucocorticoid signaling pathways thereby regulating gene expression linked to inflammatory and allergic responses Mometasone furoate exerts its biological activity primarily through binding to cytoplasmic glucocorticoid receptors forming an activated complex that translocates into the nucleus and modulates target gene transcription This mechanism suppresses inflammatory cytokine production and inhibits inflammatory mediator release Based on these pharmacological properties Mometasone furoate holds research potential in experimental models of skin inflammatory disorders such as eczema and psoriasis as well as respiratory inflammatory processes including asthma
Medchemexpress LLC Nitrofurantoin | 67-20-9 | MFCD00003224 | 99.7% | C8H6N4O5 | 1 ML
Nitrofurantoin is a potent, orally active, broad-spectrum beta-lactamase antimicrobial agent. It functions as an antibiotic, making it suitable for research into urinary tract infections (UTIs), including cystitis and kidney infections.
- Potent broad-spectrum antimicrobial agent
- Antibiotic for urinary tract infection research
- Purity of 99.7%
- Soluble in DMSO (100 mg/mL)
- Light yellow to yellow solid appearance
- For research use only
eMolecules 2,3-Difluoro-4-ethoxybenzoic acid | 124728-45-6 | MFCD02258849 | 5g
Apollo Scientific | 2,3-Difluoro-4-ethoxybenzoic acid | 5g | 562456355 | PC7871 | 97.000 | 124728-45-6 | MFCD02258849 | 202.157 | C9H8F2O3
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![Medchemexpress LLC 4-[1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-... | 873551-53-2 | 99.3% | 358.41 g/mol | C18H23FN6O | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000214055.png-250.jpg)
Medchemexpress LLC 4-[1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-... | 873551-53-2 | 99.3% | 358.41 g/mol | C18H23FN6O | 10 MG
FTIDC is a selective, noncompetitive allosteric antagonist of metabotropic glutamate receptor 1 (mGluR1) intended for research use. It is orally active and demonstrates potent antagonism against recombinant mGluR1, supporting pharmacology and neuroscience studies.
- Potent mGluR1 antagonism (IC50 5.8 nM for human mGluR1a).
- Selective noncompetitive allosteric mechanism.
- High chemical purity suitable for research applications.
- Defined physicochemical properties: C18H23FN6O; MW 358.41 g/mol; CAS 873551-53-2.
- Supplied in small-scale quantities appropriate for laboratory experiments.
Medchemexpress LLC Nav1.1 activator 1 | 2332897-85-3 | 99.0% | 440.46 | 10 MG
Nav1.1 activator 1 (compound 4) is a highly potent Nav1.1 activator with BBB penetration, which increases the decay time constant (tau) of Nav1.1 currents at 0.03 μM, demonstrating significant selectivity against Nav1.2, Nav1.5, and Nav1.6.
- A valuable Nav1.1 activator for further evaluation of pathophysiological functions of the Nav1.1 channel.
- Has potential for therapeutic treatments of Central Nervous System (CNS) diseases like Dravet syndrome.
- Intraperitoneal administration (30 mg/kg) in mice achieved sufficient brain exposure (193 ng/g 1 hour after administration), corresponding to 13 nM of free brain concentration, comparable to its in vitro potency.
- Capable of penetrating the blood-brain barrier (BBB) in humans.
Medchemexpress LLC Dantrolene (sodium salt) | 14663-23-1 | 99.5% | 336.2 | 100 MG
Dantrolene sodium is an orally active, non-competitive glutathione reductase inhibitor and a calcium channel protein inhibitor. It inhibits the release of Ca²± from RyR1 and RyR3, which is beneficial in pathologies caused by disruptions in calcium homeostasis, such as stroke and neurodegenerative diseases. It also offers relief of muscle spasms, malignant hyperthermia, and has antitoxic, antipyretic, and anti-inflammatory properties.
- Orally active glutathione reductase and calcium channel inhibitor
- Inhibits Ca²± release from RyR1 and RyR3
- Beneficial in calcium homeostasis disruptions
- Relieves muscle spasms and malignant hyperthermia
- Antitoxic, antipyretic, and anti-inflammatory effects
- Targets calcium channel, ROS, and apoptosis
- Used in cardiovascular, neurological, and metabolic disease research
Medchemexpress LLC CCT365623 hydrochloride | 2126136-98-7 | 98.1% | 443.99 g/mol | C18H18ClNO4S3 | 5MG
CCT365623 hydrochloride is the hydrochloride salt of a small-molecule lysyl oxidase (LOX) inhibitor used in preclinical research. It suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF, and has reported oral activity and favorable pharmacokinetic properties. The material is supplied as a solid and as a prepared DMSO solution for laboratory use and is intended for research use only.
Medchemexpress LLC Ry796 | 1393441-53-6 | 98.6% | 5 MG
RY796 is a potent, selective inhibitor of voltage-gated potassium (KV2) channels used in preclinical research; it shows analgesic activity and inhibits KV2.1 and KV2.2 with IC50 values in the submicromolar range.
- Selective KV2 channel inhibitor (IC50: 0.25 μM for KV2.1, 0.09 μM for KV2.2).
- Demonstrates analgesic activity in preclinical models.
- High research-grade purity (98.6%).
- Soluble in DMSO at 100 mg/mL; in vivo formulations documented.
- Stable as a powder at standard low-temperature storage conditions.
eMolecules 328968-36-1 | Medchem Express | C646 | 10mg | 446263588 | HY-13823 | MFCD06125650 | 445.431 | C24H19N3O6
Medchem Express | Sofiniclin | 1mg | 415687348 | HY-14824 | 799279-80-4 | MFCD19443714 | 244.120 | C10H11Cl2N3
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eMolecules 1285702-20-6 | Medchem Express | ML167 | 5mg | 446267012 | HY-15951 | MFCD27978379 | 335.363 | C19H17N3O3
Medchem Express | AG-825 | 5mg | 572596898 | HY-15844 | 149092-50-2 | MFCD01074971 | 397.470 | C19H15N3O3S2
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Medchemexpress LLC CCT365623 hydrochloride | 2126136-98-7 | 98.1% | 443.99 | C18H18ClNO4S3 | 100MG
CCT365623 hydrochloride is a research-grade small molecule lysyl oxidase (LOX) inhibitor used in biochemical and cellular studies. It is supplied as a solid (white to yellow) with reported potency IC50 0.89 μM against LOX. Analytical purity is 98.07%, molecular weight 443.99, and formula C18H18ClNO4S3. The compound is highly soluble in DMSO (250 mg/mL) and is hygroscopic in solution; store sealed and away from moisture, with solvent storage recommended at -80°C (up to 6 months) or -20°C (up to 1 month).
- Potent LOX inhibition with reported IC50 0.89 μM.
- High analytical purity of 98.07%.
- Molecular weight 443.99.
- Chemical formula C18H18ClNO4S3.
- Soluble in DMSO at 250 mg/mL; ultrasonic aid may be required.
- Solid, white to yellow; hygroscopic in DMSO.
- Store sealed away from moisture; solvent storage -80°C (6 months).
Chem-Impex International, Inc. 3-Furancarboxylic acid methyl ester | MFCD06203671 | 25G
3-Furancarboxylic acid methyl ester, MFCD06203671, 25G
eMolecules 1202916-90-2 | Medchem Express | CX-6258 | 5mg | 446268890 | HY-18095 | MFCD28142834 | 461.95 | C26H24ClN3O3
Ambeed | Boc-D-Serinol(Bzl) | 1g | 525186612 | A325274 | 127559-33-5 | MFCD00235944 | 281.352 | C15H23NO4
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