Furans
Medchemexpress LLC Furazolidone | 67-45-8 | MFCD00010550 | 1 ML
Furazolidone is a monoamine oxidase (MAO) inhibitor that possesses antiproliferative, apoptosis-inducing, and differentiation-promoting characteristics. It has the potential to inhibit leukemia fusion protein-mediated bone marrow transformation by increasing the stability of the tumor suppressor protein p53. Furthermore, Furazolidone demonstrates anti-leukemic activity in acute myeloid leukemia (AML) cell lines and is suitable for anti-AML research.
- Monoamine oxidase (MAO) inhibitor.
- Exhibits antiproliferative activity.
- Induces apoptosis.
- Promotes differentiation.
- May inhibit leukemia fusion protein-mediated bone marrow transformation.
- Upregulates the stability of tumor suppressor protein p53.
- Shows anti-leukemic activity in acute myeloid leukemia (AML) cell lines.
- Can be used for anti-AML research.
Medchemexpress LLC Danshenxinkun A | 65907-75-7 | MFCD08689944 | 5 MG
Danshenxinkun A is a natural compound isolated from Tanshen, utilized in studies related to heart diseases. It is intended for research use only.
- Purity: 99.70%
- Molecular weight: 296.32
- Formula: C18H16O4
- Appearance: Solid
- Color: Light yellow to orange
- Structure classification: Quinones, Naphthalene Quinones
- Initial source: Plants
- Solubility in DMSO: ≥ 100 mg/mL
- In vivo solubility: 2.5 mg/mL for oral and intraperitoneal injection
- Inhibits HIF1 activation in AGS cells (IC50 > 20 μM)
- Inhibits HIF1 activation in Hep 3B2 cells (IC50 > 20 μM)
- Does not significantly affect AGS cell viability under normoxic conditions (IC50 > 50 μM)
- Does not significantly affect Hep 3B2 cell viability under normoxic conditions (IC50 > 50 μM)
Medchemexpress LLC Sincalide (ammonium) | 70706-98-8 | 99.2% | 1160.30 | 10 MG
Sincalide ammonium is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. It is a major bioactive segment of CCK that retains most of its biological activities. CCK-8 can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders, increasing bile secretion, causing gallbladder contraction, and relaxing the sphincter of Oddi for bile drainage into the duodenum.
- Significant inhibitory effect on myocardial fibrosis in noninfarcted areas
- Positive role in fighting inflammation, apoptosis, and collagen deposition
- Protects H9c2 cardiomyoblasts from Ang II‐induced apoptosis
- Alleviates fibrosis in noninfarcted regions
- Delays left ventricular remodeling and the progress of heart failure in a MI rat model
Medchemexpress LLC Bliretrigine | 1233229-75-8 | 99.4% | C20H24N4O2 | 50 MG
Bliretrigine is a sodium channel blocker that has the effect of relieving pain.
- Sodium channel blocker
- Relieves pain
- White to off-white solid appearance
- Stable under recommended storage conditions
Medchemexpress LLC BMS-911172 50mg | 1644248-18-9 | 339.34 g/mol | C16H19F2N3O3 | 50 MG
BMS-911172 is a small-molecule, brain-penetrant inhibitor of adaptor protein 2-associated kinase 1 (AAK1) supplied as a 50 mg solid for research use only. It was developed as a tool compound to validate AAK1 as a target for neuropathic pain; reported potency varies across sources.
- Inhibits AAK1 with reported IC50 in the low nanomolar range (reported values 12-35 nM).
- Brain-penetrant small molecule suitable for in vitro and in vivo studies.
- Supplied as a solid at 50 mg quantity.
- High supplier-reported purity (typically ≥99%).
- Provided for research use only; not for human therapeutic use.
Medchemexpress LLC BMS-911172 25mg | 1644248-18-9 | 339.34 g/mol | C16H19F2N3O3 | 25 MG
BMS-911172 is a small-molecule, brain-penetrant inhibitor of adaptor protein 2-associated kinase 1 (AAK1) used as a research compound to investigate AAK1-mediated signaling and neuropathic pain mechanisms. Chemical formula C16H19F2N3O3; molecular weight 339.34 g/mol; reported AAK1 activity in the low-nanomolar range.
- Potent AAK1 inhibition with low-nanomolar activity.
- Brain-penetrant small molecule suitable for in vivo models.
- High purity appropriate for biochemical and cellular assays.
- Available in small research quantities for laboratory studies.
Medchemexpress LLC SEW2871 | 256414-75-2 | 99.9% | 440.36 | 10 MG
SEW2871 is an orally active, potent, highly selective S1P1 (sphingosine-1-phosphate type 1 receptor) agonist, with an EC50 of 13.8 nM. It activates ERK, Akt, and Rac signaling pathways and induces S1P1 internalization and recycling. SEW2871 reduces lymphocyte numbers in blood and can be used for the research of diabetes, Alzheimer's disease, liver fibrosis, and inflammatory responses.
- Orally active, potent, highly selective S1P1 agonist.
- Activates ERK, Akt, and Rac signaling pathways.
- Induces S1P1 internalization and recycling.
- Reduces lymphocyte numbers in blood.
- Can be used for research of diabetes, Alzheimer's disease, liver fibrosis, and inflammatory responses.
Medchemexpress LLC ATH686 | 853299-52-2 | 99.5% | 515.53 | 50 MG
ATH686 is a potent, selective, and ATP-competitive FLT3 inhibitor. It targets mutant FLT3 protein kinase activity, inhibiting the proliferation of cells harboring FLT3 mutants by inducing apoptosis and cell cycle inhibition. It has demonstrated antileukemic effects.
- Potent, selective, and ATP-competitive FLT3 inhibitor.
- Targets mutant FLT3 protein kinase activity.
- Induces apoptosis and cell cycle inhibition.
- Inhibits proliferation of cells harboring FLT3 mutants.
- Demonstrates antileukemic effects.
- For research use only.
Medchemexpress LLC Epoxiconazole | 133855-98-8 | 99.0% | 25 MG
Epoxiconazole is a triazole-class fungicide and demethylation inhibitor of ergosterol biosynthesis, supplied as a high-purity analytical reagent for laboratory research.
- Triazole fungicide and ergosterol biosynthesis inhibitor.
- High purity, 99.0% (as supplied).
- Chemical formula C17H13ClFN3O; molecular weight 329.76 g/mol.
- Suitable as a reference standard or reagent for biochemical assays.
- Available as a small-scale solid dose for analytical testing.
- Includes datasheet and safety data sheet for handling and storage guidance.
Medchemexpress LLC Chdi-390576 | 1629729-98-1 | 98.1% | 10 MG
A small-molecule, cell-permeable, CNS-penetrant class IIa histone deacetylase (HDAC) inhibitor for research use. It is suitable for biochemical and cellular assays to study HDAC biology and related pathways. Available as a solid and in ready-to-use DMSO solutions with recommended cold storage.
- Potent inhibition of class IIa HDAC isoforms (reported IC50s: HDAC4 54 nM, HDAC5 60 nM, HDAC7 31 nM, HDAC9 50 nM).
- High selectivity over class I and other HDAC isoforms (>500-fold vs class I; ~150-fold vs HDAC8 and HDAC6).
- High purity supply (approximately 98.1%).
- Supplied as powder and as 10 mM solutions in DMSO; recommended storage: powder -20°C, in solvent -80°C (short term at -20°C).
- Intended for research use only; not for human or diagnostic applications.
Medchemexpress LLC 3-Furaldehyde | 498-60-2 | 99.9% | C5H4O2 | 1 G
3-Furaldehyde is a furan aldehyde used in the synthesis of the neoclerodane diterpene Salvinorin A. It is also recognized as an atmospheric pollutant, predominantly resulting from biomass burning, and is known to undergo photoisomerization and photolysis reactions under ultraviolet light.
- Used in the synthesis of Salvinorin A
- Recognized as an atmospheric pollutant
- Undergoes photoisomerization and photolysis under UV light
- Appears as a colorless to light yellow liquid
- Purity is 99.9%
- Soluble in DMSO at 100 mg/mL
Medchemexpress LLC Nitrofurantoin | 67-20-9 | MFCD00003224 | 99.7% | C8H6N4O5 | 1 ML
Nitrofurantoin is a potent, orally active, broad-spectrum beta-lactamase antimicrobial agent. It functions as an antibiotic, making it suitable for research into urinary tract infections (UTIs), including cystitis and kidney infections.
- Potent broad-spectrum antimicrobial agent
- Antibiotic for urinary tract infection research
- Purity of 99.7%
- Soluble in DMSO (100 mg/mL)
- Light yellow to yellow solid appearance
- For research use only
Medchemexpress LLC Nitrofurantoin | 67-20-9 | 238.16 | 5 G
Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. It acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections.
- Potent and orally active broad-spectrum beta-lactamase antimicrobial agent
- Acts as an antibiotic
- Used for the study of urinary tract infections (UTIs), including cystitis and kidney infections
- Targets bacteria
- Melting/freezing point of 268°C
Medchemexpress LLC BV02 | 292870-53-2 | MFCD00356631 | 99.8% | 377.36 | C20H15N3O5 | 50 MG
BV02 is a small-molecule research compound that inhibits 14-3-3 protein-protein interactions and has reported antibacterial activity. It modulates cell signaling by enhancing PARP and caspase-3 cleavage, and by inducing apoptosis and autophagy, making it useful for cellular and infection-related studies.
- Inhibits 14-3-3 protein-protein interactions.
- Induces apoptosis and autophagy in cell-based assays.
- Enhances PARP and caspase-3 cleavage.
- Shows reported antibacterial activity.
- Supplied at high purity suitable for research use.
- Available in solid and ready-to-use solution formats.
Medchemexpress LLC Pyribencarb | 799247-52-2 | MFCD22200855 | 98.8% | 361.83 | C18H20ClN3O3 | 10 MG
Pyribencarb is a benzylcarbamate-type fungicide supplied as a research-grade reagent. It acts as a Qo inhibitor of cytochrome b and is active against a broad range of plant pathogenic fungi. Offered in solid form and as a DMSO solution for laboratory and analytical applications.
- High purity (98.8%).
- Molecular formula C18H20ClN3O3, molecular weight 361.83.
- Available in multiple pack sizes for small-scale research.
- Provided as solid and 10 mM solution in DMSO for convenience.
- Suitable for antifungal research and biochemical assays.