Furans
Medchemexpress LLC 2H-indol-2-one, 1,3-dihydro-3-(2-pyridinylmethylene)-(3Z)- | 187325-53-7 | 98.0% | 222.25 g/mol | C14H10N2O | 50MG
GSK-3β inhibitor 1 is a small-molecule inhibitor of glycogen synthase kinase-3 beta (CAS 187325-53-7) with low-nanomolar biochemical potency and reported antidiabetic efficacy in obese streptozotocin-treated rats. The compound is provided as a solid for research use and is soluble in DMSO with recommended storage conditions for powder and solutions.
Medchemexpress LLC Danshenxinkun A | 65907-75-7 | MFCD08689944 | 5 MG
Danshenxinkun A is a natural compound isolated from Tanshen, utilized in studies related to heart diseases. It is intended for research use only.
- Purity: 99.70%
- Molecular weight: 296.32
- Formula: C18H16O4
- Appearance: Solid
- Color: Light yellow to orange
- Structure classification: Quinones, Naphthalene Quinones
- Initial source: Plants
- Solubility in DMSO: ≥ 100 mg/mL
- In vivo solubility: 2.5 mg/mL for oral and intraperitoneal injection
- Inhibits HIF1 activation in AGS cells (IC50 > 20 μM)
- Inhibits HIF1 activation in Hep 3B2 cells (IC50 > 20 μM)
- Does not significantly affect AGS cell viability under normoxic conditions (IC50 > 50 μM)
- Does not significantly affect Hep 3B2 cell viability under normoxic conditions (IC50 > 50 μM)
Medchemexpress LLC Bliretrigine | 1233229-75-8 | 99.4% | C20H24N4O2 | 10MG
Bliretrigine is a small-molecule sodium channel blocker used in research with reported analgesic effects. The product is provided as a white to off-white solid with specified solubility in DMSO and defined storage recommendations for both powder and solution forms.
- Sodium channel blocker with analgesic activity.
- Molecular formula C20H24N4O2.
- Molecular weight 352.43.
- Purity 99.42%.
- Appearance white to off-white solid.
- Soluble in DMSO at 50 mg/mL; may require ultrasonic assistance.
- Store powder at -20°C for up to 3 years or at 4°C for up to 2 years.
- Store in solution at -80°C for up to 6 months or at -20°C for up to 1 month.
Medchemexpress LLC Batabulin sodium | 195533-98-3 | MFCD22380600 | 99.8% | 393.24 g/mol | C13H6F6NNaO3S | 5 MG
Batabulin sodium is a sodium salt antitumor research compound that covalently and selectively binds specific β-tubulin isotypes, disrupting microtubule polymerization, inducing G2/M cell-cycle arrest, and triggering apoptotic cell death. Supplied as an off-white to light-yellow solid for in vitro and in vivo research applications.
- Covalently binds to a subset of β-tubulin isotypes.
- Disrupts microtubule polymerization and induces G2/M arrest.
- Induces apoptosis in cell-based assays.
- High reported purity (~99.8%).
- Soluble in DMSO; use freshly opened solvent and ultrasonic assistance if needed.
- Store powder at 4°C; in solution store at -80°C for long-term stability.
Medchemexpress LLC Furazolidone | 500 MG
Furazolidone is a monoamine oxidase (MAO) inhibitor with antiproliferative, apoptosis-inducing and differentiation-promoting activities. It may inhibit leukemia fusion protein-mediated bone marrow transformation by upregulating the stability of the tumor suppressor protein p53, and exhibits anti-leukemic activity in acute myeloid leukemia (AML) cell lines.
- Inhibits monoamine oxidase (MAO).
- Demonstrates antiproliferative activity.
- Induces apoptosis.
- Promotes differentiation.
- May inhibit leukemia fusion protein-mediated bone marrow transformation.
- Upregulates stability of tumor suppressor protein p53.
- Exhibits anti-leukemic activity in acute myeloid leukemia (AML) cell lines.
- Suitable for anti-AML research.
Medchemexpress LLC CK2 inhibitor 2 | 2641079-92-5 | 98.5% | C21H17ClN4O2 | 10MG
CK2 inhibitor 2 is a potent, selective, orally active small-molecule inhibitor of casein kinase 2 (CK2) with sub-nanomolar enzymatic potency and documented cellular activity. Supplied as a solid for research use, it includes solubility data for DMSO and recommended storage conditions for powder and solutions.
- Potent CK2 inhibition (IC50 0.66 nM) for biochemical assays.
- Selectable kinase profile with measurable activity against Clk2.
- Cellular activity in multiple cancer cell lines at low micromolar concentrations.
- High purity suitable for biochemical and cell-based studies (98.5%).
- Documented solubility in DMSO and example in vivo formulation options.
- Defined storage recommendations for powder and solvent preparations.
Medchemexpress LLC Cobomarsen (MRG-106) | 1848257-52-2 | 4736.00 g/mol | C148H177N52O77P13S13 | 5 MG
Cobomarsen (MRG-106) is a locked nucleic acid-modified oligonucleotide inhibitor of microRNA-155 (miR-155) used in preclinical research to reduce cellular proliferation and survival by modulating multiple signaling pathways. The material is supplied as a solid research-grade compound and should be handled per the manufacturer's storage and handling guidance.
- Inhibits miR-155 to modulate JAK/STAT, MAPK/ERK, and PI3K/AKT signaling.
- Designed as an LNA/modified oligonucleotide for increased affinity and stability.
- Provided as a white to off-white solid suitable for laboratory use.
- CAS 1848257-52-2; molecular weight approximately 4736.00 g/mol.
- Intended for preclinical and mechanistic studies in hematologic and lymphoid disease models.
![Medchemexpress LLC 1-[4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydrocyclopenta[c]quinolin-8-yl]ethanone | 881639-98-1 | 99.8% | 412.28 g·mol⁻¹ | C21H18BrNO3 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000239967.png-250.jpg)
Medchemexpress LLC 1-[4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydrocyclopenta[c]quinolin-8-yl]ethanone | 881639-98-1 | 99.8% | 412.28 g·mol⁻¹ | C21H18BrNO3 | 50 MG
G-1 is a nonsteroidal, high-affinity, selective agonist of GPR30 (G protein-coupled estrogen receptor) with a reported Ki of 11 nM. It is supplied as a research reagent with formula C21H18BrNO3, molecular weight 412.28 g·mol⁻¹, and high reported purity suitable for in vitro signaling studies.
- Selective GPR30 agonist (Ki = 11 nM).
- High purity (99.76%).
- Molecular formula C21H18BrNO3 and molecular weight 412.28 g·mol⁻¹.
- Soluble in DMSO for assay preparation.
- Intended for research use only; not for human use.
Medchemexpress LLC BMS-911172 50mg | 1644248-18-9 | 339.34 g/mol | C16H19F2N3O3 | 50 MG
BMS-911172 is a small-molecule, brain-penetrant inhibitor of adaptor protein 2-associated kinase 1 (AAK1) supplied as a 50 mg solid for research use only. It was developed as a tool compound to validate AAK1 as a target for neuropathic pain; reported potency varies across sources.
- Inhibits AAK1 with reported IC50 in the low nanomolar range (reported values 12-35 nM).
- Brain-penetrant small molecule suitable for in vitro and in vivo studies.
- Supplied as a solid at 50 mg quantity.
- High supplier-reported purity (typically ≥99%).
- Provided for research use only; not for human therapeutic use.
Medchemexpress LLC Epoxiconazole | 133855-98-8 | 99.0% | 25 MG
Epoxiconazole is a triazole-class fungicide and demethylation inhibitor of ergosterol biosynthesis, supplied as a high-purity analytical reagent for laboratory research.
- Triazole fungicide and ergosterol biosynthesis inhibitor.
- High purity, 99.0% (as supplied).
- Chemical formula C17H13ClFN3O; molecular weight 329.76 g/mol.
- Suitable as a reference standard or reagent for biochemical assays.
- Available as a small-scale solid dose for analytical testing.
- Includes datasheet and safety data sheet for handling and storage guidance.
Medchemexpress LLC JQKD82 trihydrochloride | 2863676-87-1 | 99.89% | 610.01 | 50 MG
JQKD82 (JADA82) trihydrochloride is a cell-permeable and selective KDM5 inhibitor. It increases H3K4me3 and can be used for the research of multiple myeloma.
- Increases global H3K4me3 levels in cells.
- Inhibits cell growth in a dose- and time-dependent manner (IC50=0.42 μM).
- Induces G1 cell-cycle arrest.
- Exhibits anti-multiple myeloma activity in vivo.
- Leads to increased H3K4me3 levels and reduced MYC immuno-staining.
- Significantly reduces tumor burden in mouse models.
Medchemexpress LLC Jnj-55308942 | 2166558-11-6 | 99.9% | 425.32 | C17H12F5N7O | 50MG
JNJ-55308942 is a selective, brain-penetrant P2X7 receptor antagonist characterized for preclinical research. It shows low-nanomolar potency against human and rodent P2X7 receptors, reduces IL-1β release in brain tissue, and is supplied as a small research quantity with high reported purity.
- Selective P2X7 receptor antagonist for target-specific studies
- Brain-penetrant, suitable for central nervous system research
- Low-nanomolar potency in human and rodent assays
- Reduces IL-1β release in brain tissue models
- High purity (~99.9%) for reliable assay results
- Provided as a 50 mg research quantity
- Molecular weight 425.32; formula C17H12F5N7O
Medchemexpress LLC Methyl protogracillin | 54522-53-1 | MFCD32197353 | 99.0% | 1079.23 | C52H86O23 | 10 MG
Methyl protogracillin is a steroidal saponin natural product isolated from the roots of Dioscorea opposite Thunb. It has reported anticancer activity and is supplied for laboratory research use as a solid with high purity.
- Steroidal saponin natural product isolated from plant roots.
- Reported anticancer activity in the literature.
- High purity suitable for research (99.03%).
- Supplied as a solid in a 10 mg pack size.
- Molecular weight 1,079.23; formula C52H86O23.
- Store at -20°C and protect from light; follow laboratory safety procedures.