Furans
Medchemexpress LLC Methyl 2-furoate | 611-13-2 | MFCD00003236 | 99.9% | 126.11 g/mol | C6H6O3 | 250g
Methyl 2-furoate (Methyl furan-2-carboxylate) can be used to synthesize cis-fused 5-oxofuro[2 3-b]furans Methyl 2-furoate is also used in the preparation of sesquiterpene lactones[1]
eMolecules 1314118-94-9 | MK2-IN-1 hydrochloride | MFCD29472226 | 25mg
ChemScene | (S)-tert-Butyl (3-hydroxy-11-diphenylpropan-2-yl)carbamate | 100mg | 694122996 | CS-W013937 | 155836-47-8 | MFCD01863566 | 327.424 | C20H25NO3
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Medchemexpress LLC Maytansine | 35846-53-8 | MFCD28127038 | 99.8% | C34H46ClN3O10 | 10MG
Maytansine is a highly potent microtubule-targeted natural product that induces mitotic arrest and kills tumor cells at subnanomolar concentrations. It is used as a research reagent to study microtubule dynamics and as a cytotoxic payload in antibody-drug conjugate (ADC) development.
- Potent microtubule inhibitor active at subnanomolar concentrations.
- Useful for cell biology and biochemical assays of microtubule dynamics.
- Commonly used as a cytotoxic payload in ADC development and conjugation research.
- High purity suitable for research use (99.8%).
- Available in small milligram pack sizes for laboratory experiments.
Apexbio Technology LLC Azimilide 149908-53-2 5mg
Azimilide (CAS 149908-53-2) is a small molecule under investigation for potential anti-arrhythmic activity classified pharmacologically as a class III anti-arrhythmic agent Its mechanism involves inhibition of cardiac delayed rectifier potassium channels specifically targeting both rapid (IKr) and slow (IKs) components By modulating these currents azimilide prolongs cardiac repolarization influencing cardiac rhythm Although not approved for therapeutic use azimilide is currently undergoing clinical evaluation in the United States and serves as a tool compound in arrhythmia-related biomedical research
Apexbio Technology LLC Azimilide 149908-53-2 50mg
Azimilide (CAS 149908-53-2) is a small molecule under investigation for potential anti-arrhythmic activity classified pharmacologically as a class III anti-arrhythmic agent Its mechanism involves inhibition of cardiac delayed rectifier potassium channels specifically targeting both rapid (IKr) and slow (IKs) components By modulating these currents azimilide prolongs cardiac repolarization influencing cardiac rhythm Although not approved for therapeutic use azimilide is currently undergoing clinical evaluation in the United States and serves as a tool compound in arrhythmia-related biomedical research
Medchemexpress LLC PAR-2-IN-1 | 1690176-75-0 | 98.9% | 267.71 | 50 MG
PAR-2-IN-1 is a protease-activated receptor-2 (PAR2) signaling pathway inhibitor. It demonstrates anti-inflammatory and anticancer effects.
- Protease-activated receptor-2 (PAR2) signaling pathway inhibitor
- Exhibits anti-inflammatory effects
- Demonstrates anticancer effects
- Related to cancer targeted therapy and cancer metabolism
- Acts on GPCR/G protein and protease activated receptor (PAR) pathways
Medchemexpress LLC AZ10606120 dihydrochloride | 607378-18-7 | 99.9% | 495.48 | 100 MG
AZ10606120 dihydrochloride is a selective, high-affinity antagonist for the P2X7 receptor (P2X7R) in human and rat, with an IC50 of approximately 10 nM. It shows minimal to no effect on other P2XR subtypes. This compound demonstrates anti-depressant properties and has been observed to reduce tumor growth.
- Selective, high-affinity antagonist for P2X7 receptor
- Minimal cross-reactivity with other P2XR subtypes
- Exhibits anti-depressant effects
- Reduces tumor growth in various models
- Depletes tumor cells in patient-derived glioblastoma samples
- Increases lactate dehydrogenase levels in human glioblastoma cultures
- Reduces proliferation, cell migration, and invasion in PDAC cell lines
- Reverses streptozotocin-induced VEGF and IL-6 expression in rat retinae
Medchemexpress LLC 2-pyrazinecarboxamide, 3-amino-N-(aminoiminomethyl)-5-(dimethylamino)-6-(2-phenylethynyl)-hydrochloride | 2237925-62-9 | 98.0% | C16H18ClN7O | 10MG
DMA-135 hydrochloride is the hydrochloride salt of a small-molecule ligand that targets the enterovirus 71 (EV71) SLII RNA domain and inhibits EV71 IRES-dependent translation and replication; it has a reported KD of ~520 nM and shows no significant toxicity in cell-based studies. Provided as a light-yellow solid with high purity for biochemical and cellular research.
- Binds EV71 SLII RNA with moderate affinity.
- Inhibits IRES-dependent translation and viral replication in vitro.
- High purity suitable for biochemical and cell-based assays.
- Available as solid and as 10 mM solution in DMSO.
- Light yellow solid appearance for easy visual inspection.
- Stable when stored sealed; follow recommended temperature guidelines.
Medchemexpress LLC Nitrofurazone | 59-87-0 | 99.96% | 1 ML
Nitrofurazone (Nitrofural) is a broad-spectrum, nitro-aromatic antibiotic with oral activity. It is effective against both Gram-positive and Gram-negative bacteria, making it suitable for research into various infections and skin conditions.
- Active against Gram-positive and Gram-negative bacteria.
- Useful in research for various infections and skin conditions.
- Inhibits RNA and ribosomal subunit synthesis.
- Can be used to create breast tumor models.
- Powder storage: -20°C for 3 years; 4°C for 2 years.
- Storage in solvent: -80°C for 2 years; -20°C for 1 year.
Medchemexpress LLC Methyl 2-furoate | 611-13-2 | MFCD00003236 | 99.9% | 126.11 g·mol⁻1 | C6H6O3 | 100g
Methyl 2-furoate (Methyl furan-2-carboxylate) can be used to synthesize cis-fused 5-oxofuro[2 3-b]furans Methyl 2-furoate is also used in the preparation of sesquiterpene lactones[1]
Medchemexpress LLC Nitrofurazone-13C,15N2 | 1217220-85-3 | 99.6% | 5 MG
Nitrofurazone-13C,15N2, also known as Nitrofural-13C,15N2, is a 13C and 15N labeled derivative of Nitrofurazone. This antibiotic is used topically to treat wounds, burns, ulcers, and skin infections, and in surfactant preparation. It may also affect ecosystem function in marine environments. The stable heavy isotopes are incorporated into drug molecules as tracers for quantitation during drug development.
- Used as a tracer
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Supports studies on pharmacokinetic and metabolic profiles of drugs
- Aids in combating various microorganisms
- Applied in the preparation of surfactants