Furans
Medchemexpress LLC C-021 | 864289-85-0 | 100.0% | 467.65 g/mol | C27H41N5O2 | 5 MG
C-021 is a small-molecule antagonist of the CC chemokine receptor 4 (CCR4) used for research into GPCR signaling and immunology. It inhibits CCR4-mediated chemotaxis in human and mouse systems and is supplied as a solid for laboratory studies.
- Target CCR4.
- Molecular formula C27H41N5O2.
- Molecular weight 467.65 g/mol.
- Purity 99.95%.
- Appearance solid, off-white to light yellow.
- Storage powder: -20°C (up to 3 years); in solvent: -80°C (short-term).
- Supplied in small research quantities.
![Medchemexpress LLC Urea, N-[4-[8-amino-3-(1-methylethyl)imidazo[1,5-a]pyrazin-1-yl]-1-naphthalenyl]-N'-[3-(trifluoromethyl)phenyl]- | 1414938-21-8 | 99.2% | 504.51 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000387909-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Urea, N-[4-[8-amino-3-(1-methylethyl)imidazo[1,5-a]pyrazin-1-yl]-1-naphthalenyl]-N'-[3-(trifluoromethyl)phenyl]- | 1414938-21-8 | 99.2% | 504.51 | 5 MG
IRE1α kinase-IN-2 is a potent IRE1α kinase inhibitor with an EC50 of 0.82 μM. It inhibits IRE1α kinase autophosphorylation (IC50=3.12 μM) and XBP1 mRNA splicing in WT cell lines.
- Potent IRE1α kinase inhibitor.
- Inhibits IRE1α kinase autophosphorylation.
- Inhibits XBP1 mRNA splicing.
- For research use only.
Medchemexpress LLC Ganoderal A | 104700-98-3 | 5 MG
Ganoderal A is an oxygenated sterol derived from *Ganoderma lucidum*. It functions as a cholesterol synthesis inhibitor and is intended for research use only.
- Oxygenated sterol derived from *Ganoderma lucidum*.
- Functions as a cholesterol synthesis inhibitor.
- Purity: 97.54%.
Medchemexpress LLC BMS-911172 10mg | 1644248-18-9 | 339.34 | C16H19F2N3O3 | 10 MG
BMS-911172 is a small-molecule inhibitor of adaptor-associated kinase 1 (AAK1) provided for laboratory research. It has reported nanomolar potency and is offered at high purity for biochemical and cellular studies.
- Selective AAK1 inhibition with nanomolar potency (IC50 ≈ 35 nM).
- High reported purity (≈99.5%).
- Molecular weight 339.34; formula C16H19F2N3O3.
- Soluble in DMSO; solution format available.
- Available in small-scale quantities suitable for research workflows.
- For research use only; not for clinical or human use.
Medchemexpress LLC Pyribencarb | 799247-52-2 | MFCD22200855 | ≥95.0% | 361.83 g/mol | C18H20ClN3O3 | 100 MG
Pyribencarb (CAS 799247-52-2) is a benzylcarbamate-type fungicide provided as an analytical/research standard. It acts at the Qo site of fungal complex III and is used in studies of plant pathogenic fungi, antifungal screening, and fungal biochemistry.
- High chemical purity suitable for analytical applications.
- Useful as a research standard for antifungal activity assays.
- Stable solid form for reliable storage and handling.
- Provides reproducible inhibition of fungal respiratory pathways.
- Compatible with common solvents for formulation and testing.
Medchemexpress LLC Complement C5-IN-1 | 2365402-67-9 | 99.14% | 50 MG
Complement C5-IN-1 is a selective allosteric inhibitor of complement component protein C5. It inhibits the cleavage of C5 into C5a and C5b, blocking the formation of the membrane attack complex (MAC). This compound demonstrates an IC50 of 0.77 μM in 50% human whole blood and 5 nM in 2% human serum for blocking MAC deposition induced by zymosan. It is valuable for studying diseases associated with complement overactivation, such as paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS). This product is for research use only.
- Selective allosteric inhibitor of complement component protein C5
- Prevents C5 from being cleaved by C5 convertase
- Inhibits cleavage of C5 into C5a and C5b
- Blocks the formation of the membrane attack complex (MAC)
- Supports research into complement overactivation diseases
- Appears as a solid, white to off-white material
Sigma Aldrich Fine Chemicals Biosciences LY 320135 >=98% (HPLC) | 176977-56-3 | MFCD00945878 | 5MG
LY 320135 >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 383.4 | 176977-56-3 | MFCD00945878 | 5MG
Medchemexpress LLC (E)-4-(2-chloro-6-fluorostyryl)-N-methylaniline | 1391934-98-7 | 98.5% | C15H13ClFN | 10MG
FIDAS-5 is a small-molecule research compound that inhibits methionine S-adenosyltransferase 2A (MAT2A). It competitively displaces S-adenosylmethionine with a reported IC50 of 2.1 μM and has demonstrated anticancer activity in preclinical studies. The material is supplied as a high-purity solid powder for laboratory research and is unstable in solution, so fresh preparations are recommended.
- Potent MAT2A inhibitor with IC50 = 2.1 μM.
- High purity (≈98.5%).
- Molecular formula C15H13ClFN; molecular weight 261.72.
- Supplied as a solid; available in small pack sizes including 10 mg.
- Powder stable at -20°C; unstable in solution, prepare fresh solutions.
- Used in preclinical and in vitro anticancer research.
![Medchemexpress LLC 2-[(2-carboxyphenyl)amino]-4-chlorobenzoic acid | 63329-53-3 | MFCD00866065 | 99.4% | 291.68 g/mol | C14H10ClNO4 | 50MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000237302.png-250.jpg)
Medchemexpress LLC 2-[(2-carboxyphenyl)amino]-4-chlorobenzoic acid | 63329-53-3 | MFCD00866065 | 99.4% | 291.68 g/mol | C14H10ClNO4 | 50MG
Lobenzarit is a small-molecule immunomodulator used in preclinical research that has reported anti-oxidative and anti-inflammatory properties. It is supplied as a high-purity research reagent (CAS 63329-53-3) and is used in vitro and in vivo to study immune modulation and anti-arthritic effects.
- High purity suitable for research use.
- Reported immunomodulatory and anti-oxidative activity.
- Available in multiple small-scale sizes for preclinical studies.
- Stable when stored under recommended conditions (powder and in solvent).
- Molecular formula C14H10ClNO4; molecular weight 291.68 g/mol.
Medchemexpress LLC 3-Pyridinecarboxamide, 6-fluoro-N-[2-fluoro-3-[[[2-iodo-4-[1,2,2,2-tetrafluoro-1-(trifluorometh | 1331922-53-2 | 98.3% | 715.23 | 50 MG
Modoflaner is an isophenylamide insecticide intended for research use only. It may act through allosteric regulation of gamma-aminobutyric acid-gated chloride channels.
- Isophenylamide insecticide
- May act through allosteric regulation of gamma-aminobutyric acid-gated chloride channels
- Effectively kills moth, xylophone, and gray planthopper
- Prevents female adult ticks from laying eggs or eggs from hatching
- White to off-white solid appearance
- Purity of 98.26%
- Store at 4°C, protected from light; in solvent at -80°C for 6 months or -20°C for 1 month, protected from light
Alkali Scientific Nitrofurantoin, 100 Grams
Nitrofurantoin, 100g is a laboratory-grade antibacterial agent commonly used for research in microbiology and pharmacology. Nitrofurantoin is effective against a wide range of Gram-positive and Gram-negative bacteria, particularly in urinary tract infections. The formulation provides a convenient bulk quantity, making it suitable for large-scale research studies or ongoing laboratory investigations. Researchers use nitrofurantoin to study its antimicrobial properties, resistance mechanisms, and its effectiveness in clinical settings. This product is designed for laboratory applications and is not intended for human consumption, ensuring that it meets the standards required for scientific and educational use in laboratory experiments.
Medchemexpress LLC Calceolarioside B | 105471-98-5 | 478.45 | 5 MG
Calceolarioside B is a phenylethanoid glycoside that can be isolated from the leaves of Akebia quinata. It inhibits RLAR activity with an IC50 value of 23.99 μM, inhibits the entry of the Omicron BA.2 pseudovirus into host cells, and reduces IL-6 levels. Calceolarioside B also possesses immunomodulatory and anticancer activities against human hormone-independent prostate cancer.
- Inhibits RLAR activity.
- Inhibits entry of Omicron BA.2 pseudovirus into host cells.
- Reduces IL-6 levels.
- Possesses immunomodulatory activity.
- Exhibits anticancer activity against human hormone-independent prostate cancer.
Medchemexpress LLC Dma-135 hydrochloride | 2237925-62-9 | 98.0% | C16H18ClN7O | 100 MG
DMA-135 hydrochloride inhibits enterovirus 71 (EV71) IRES-dependent translation and replication. It binds to enterovirus 71 (EV71) SLII domain with moderately high affinity (KD= 520 nM) and has no significant toxicity in cell-based studies.
- Inhibits enterovirus 71 (EV71) IRES-dependent translation and replication
- Binds to EV71 SLII domain with moderate affinity (KD= 520 nM)
- No significant toxicity in cell-based studies
- Induces conformational changes in RNA structure
- Stabilizes DMA135-RNA-AUF1 ternary complex
- Inhibits EV71 with an IC50 of 7.54 μM