Furans
Medchemexpress LLC 4-fluoro-N-[1-[1-(oxane-4-carbonyl)-2,3-dihydroindol-5-yl]ethyl]benzamide | 2166616-74-4 | ≥98% | 396.45 | 100 MG
LY-3381916 (IDO1-IN-5) is a potent, selective, and brain-penetrant inhibitor of IDO1 activity. It functions by binding to apo-IDO1, which lacks heme, rather than to mature heme-bound IDO1.
- Potent IDO1 inhibitor
- Selective IDO1 inhibitor
- Brain-penetrant IDO1 inhibitor
- Binds to apo-IDO1 lacking heme
- Does not show obvious agonism of aryl hydrocarbon receptor (AHR) at concentrations up to 100 μM.
Medchemexpress LLC Mometasone furoate | 83919-23-7 | 99.9% | 521.43 | 100 MG
Mometasone furoate is a glucocorticoid receptor agonist with anti-inflammatory and anti-allergic activity. It is used in topical applications for chronic skin eczema and for managing airway inflammation in asthma.
- Glucocorticoid receptor agonist
- Anti-inflammatory and anti-allergic activity
- Corticosteroid agent
- Used for topical applications in chronic skin eczema
- Used for airway inflammation management of asthma in vivo
Medchemexpress LLC Nitrofurantoin (Standard) | 67-20-9 | 99.7% | C8H6N4O5 | 250 MG
Nitrofurantoin (Standard) is the analytical standard of Nitrofurantoin, intended for research and analytical applications. It is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. It acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections.
- Analytical standard grade, supplied as an assay reference
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS
Medchemexpress LLC Ath686 | 853299-52-2 | MFCD22665713 | 99.5% | 515.53 | C25H28F3N7O2 | 10 MG
ATH686 is a potent, selective, ATP-competitive FLT3 kinase inhibitor used in research to study FLT3-mutant leukemia. It inhibits mutant FLT3 activity, induces apoptosis, and suppresses proliferation in FLT3-mutant cells.
- Potent, selective ATP-competitive FLT3 inhibition.
- Demonstrated induction of apoptosis and cell-cycle arrest in FLT3-mutant cells.
- High purity suitable for biochemical and cellular assays.
- Available as solid and as 10 mM solution in DMSO for convenience.
- Stable under recommended storage conditions for long-term use.
Medchemexpress LLC FIDAS-5 | 1391934-98-7 | 98.5% | 261.72 | 50 MG
FIDAS-5 is a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. It effectively competes against S-adenosylmethionine (SAM) for MAT2A binding and exhibits anticancer activities.
- Potent and orally active MAT2A inhibitor
- Effectively competes against S-adenosylmethionine (SAM)
- Exhibits anticancer activities
- Store powder at -20°C for 3 years or 4°C for 2 years
- Compound is unstable in solutions, freshly prepared is recommended
Sigma Aldrich Fine Chemicals Biosciences LY 320135 >=98% (HPLC) | 176977-56-3 | MFCD00945878 | 5MG
LY 320135 >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 383.4 | 176977-56-3 | MFCD00945878 | 5MG
Chem-Impex International, Inc. 2,5-Furandicarboxylic acid | MFCD00016582 | 1G
2,5-Furandicarboxylic acid, MFCD00016582, 1G
Sigma Aldrich Fine Chemicals Biosciences Ethyl 2-furoate 99% | 614-99-3 | MFCD00003237 | 100G
Ethyl 2-furoate 99% | Purity: 99% | Mol Wt: 140.14 | 614-99-3 | MFCD00003237 | 100G
Sigma Aldrich Fine Chemicals Biosciences Methyl 2-furoate >=98%, FG | 611-13-2 | MFCD00003236 | 100G
Methyl 2-furoate >=98%, FG | Purity: >=98% | Mol Wt: 126.11 | 611-13-2 | MFCD00003236 | 100G
Medchemexpress LLC Trotabresib | 1706738-98-8 | 99.7% | 383.46 | 100 MG
Trotabresib is a reversible and orally active BET inhibitor used in the study of advanced solid tumors. It inhibits the proliferation of diffuse midline glioma (DMG) cells and shows stronger antitumor activity against H3K27M mutant DMG cells than DMG wildtype.
- Reversible and orally active BET inhibitor
- Applied in studies for advanced solid tumors
- Inhibits proliferation of diffuse midline glioma (DMG) cells
- Shows stronger antitumor activity against H3K27M mutant DMG cells than DMG wildtype
Medchemexpress LLC Paederosidic acid | 18842-98-3 | MFCD28124366 | 10 MG
Paederosidic acid, isolated from P. scandens, is a chemical compound exhibiting anticancer and anti-inflammation activities. It primarily acts by inducing mitochondria-mediated apoptosis in lung cancer cells.
- Inhibits lung cancer cells by inducing mitochondria-mediated apoptosis.
- Shows effects on NCI-H1650, HCC827, and A549 cells.
- Up-regulates caspase-3, caspase-8, caspase-9, Bid, Bax.
- Down-regulates Bcl-2.
- Stimulates Cyto-C release from mitochondria.
Medchemexpress LLC Khasianine | 32449-98-2 | 5 MG
Khasianine is a steroidal glycoalkaloid obtained from black nightshade (Solanum Nigrum L.). It displays antitumor activity.
- Derived from black nightshade (Solanum Nigrum L.)
- Exhibits antitumor activity
- Steroidal glycoalkaloid