Furans
Medchemexpress LLC Bi8626 | 1875036-75-1 | 98.4% | 10 MG
BI8626 is a small-molecule inhibitor of the ubiquitin ligase HUWE1, reported with an IC50 of 0.9 μM. It is supplied as a solid for research use and includes characterization and handling data.
![Medchemexpress LLC 2H-tetrazole-2-butanoic acid, β-amino-5-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenyl]-, (βS)- | 1799681-85-8 | 98.4% | C16H14ClFN6O3 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000261361.png-250.jpg)
Medchemexpress LLC 2H-tetrazole-2-butanoic acid, β-amino-5-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenyl]-, (βS)- | 1799681-85-8 | 98.4% | C16H14ClFN6O3 | 10MG
LYS006 is a small-molecule inhibitor of leukotriene A4 hydrolase (LTA4H) developed for research into inflammatory and autoimmune disorders. It is reported to have subnanomolar to low-nanomolar potency (IC50 ≈ 2 nM) and is supplied with analytical characterization suitable for laboratory studies.
- Potent leukotriene A4 hydrolase (LTA4H) inhibitor (IC50 ≈ 2 nM).
- High purity suitable for research (≈98.4%).
- Available as solid and as DMSO solution for assay flexibility.
- Characterized by a certificate of analysis with structural confirmation.
- Intended for preclinical and pharmacology studies in inflammation and immunology.
Medchemexpress LLC 1-aminohydantoin hydrochloride | 2827-56-7 | MFCD02181047 | ≥98.0% | 151.55 | C3H6ClN3O2 | 1mL
1-Aminohydantoin hydrochloride is a major metabolite of Nitrofurantoin (HY-A0090) in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat milk et al 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of 1-Aminohydantoin hydrochloride before detection[1][2]
AdipoGen Oregon Green 488 DA
Chemical. CAS 1027558-93-5. Formula C24H14F2O7. MW 452.4. 2,7-Difluorofluorescein, also called Oregon Green 488 OG488 dye is a bright, green-fluorescent dye with excitation ideally suited to the 488 nm laser line and useful for fluorescent labeling. It has a high extinction coefficient and fluorescence quantum yield and while it is pH insensitive in the physiological range, with a pKa of 4.6 it can be used to as a fluorescent indicator for intracellular pH and monitor pH changes in acidic organelles or pathways. OG488 is a fluorinated analog of fluoresceins. The absorption and emission spectra of OG488 perfectly match those of fluorescein. Because of the near match of the absorption maxima on proteins ~498 nm and ~512 nm to the strong 488 nm and 514 nm spectral lines of the argon-ion laser, the Oregon Green 488 fluorphore is an important dye for both confocal laser-scanning microscopy and flow cytometry applications.
Medchemexpress LLC Gunagratinib | 2211082-53-8 | 98.5% | 423.47 g·mol⁻¹ | C22H25N5O4 | 5 MG
Gunagratinib is a covalent, orally active pan-FGFR inhibitor supplied as a purified research compound for preclinical studies. It irreversibly inhibits FGFR signaling through covalent binding and is provided in multiple small-scale pack sizes and formats for use in in vitro and in vivo research.
- Covalent pan-FGFR inhibitor with irreversible binding.
- Orally active compound suitable for preclinical studies.
- High purity (98.5%) for research applications.
- Molecular formula C22H25N5O4; molecular weight 423.47 g·mol⁻¹.
- Available in small pack sizes (including 5 mg) as solid or DMSO solution.
- Supplied for laboratory research use only.
Medchemexpress LLC Batabulin sodium | 195533-98-3 | MFCD22380600 | 99.8% | C13H6F6NNaO3S | 10MG
Batabulin sodium is the sodium salt of batabulin, a tubulin-targeting antitumor research compound that covalently binds a subset of β-tubulin isotypes and disrupts microtubule dynamics, inducing apoptosis in cell models. It is supplied as a high-purity reagent for biochemical and cellular studies of microtubules, tubulin covalent modification, and related pharmacology.
- Covalently binds a subset of β-tubulin isotypes and disrupts microtubule dynamics.
- Used to study apoptosis, cell division, and tubulin-targeting pharmacology.
- Supplied as a high-purity research reagent (99.8%).
- Provided in multiple pack sizes and concentration formats for lab use.
- Sodium salt form suitable for biochemical and cell-based assays.
Medchemexpress LLC Etiocholanolone (5β-androsterone) | 53-42-9 | MFCD00064133 | 99.5% | 290.44 g/mol | C19H30O2 | 5 MG
Etiocholanolone (5β-androsterone) is an endogenous metabolite of testosterone provided as a high-purity research standard. It demonstrates anticonvulsant activity and functions as a neurosteroid positive allosteric modulator (PAM) of GABAA receptors, making it useful for biochemical, pharmacological, and analytical applications.
Medchemexpress LLC DS08210767 | 2376334-75-5 | 99.4% | 513.67 | C31H39N5O2 | 5MG
DS08210767 is a small-molecule, orally bioavailable antagonist of the parathyroid hormone receptor 1 (PTHR1) with a reported IC50 of 90 nM. It is supplied for research use only and is provided as a light yellow solid intended for laboratory applications.
- Orally bioavailable PTHR1 antagonist with an IC50 of 90 nM.
- High chemical purity of 99.4%.
- Molecular weight 513.67 and chemical formula C31H39N5O2.
- Supplied as a light yellow solid suitable for laboratory research.
- Provided in a 5 mg quantity for experimental use.
Medchemexpress LLC Inx-sm-56 | 2734878-18-1 | 99.5% | 576.70 g/mol | C32H36N2O6S | 5 MG
INX-SM-56 is an ADC cytotoxin intended for use in the synthesis of anti-VISTA antibody-agent conjugates. It is supplied as a solid (white to yellow) with high reported purity, and it has defined solubility and storage profiles suitable for research applications.
- Cas number 2734878-18-1.
- Purity 99.5%.
- Molecular formula C32H36N2O6S.
- Molecular weight 576.70 g/mol.
- Form solid, white to yellow.
- Soluble in DMSO ≥ 50 mg/mL; in vivo formulation ≥ 1.25 mg/mL in 10% DMSO/90% corn oil.
- Store sealed, away from moisture and light; in solvent: -80°C up to 6 months, -20°C up to 1 month.
- Available pack sizes include 1 mg and 5 mg.
Medchemexpress LLC 1-aminohydantoin hydrochloride | 2827-56-7 | MFCD02181047 | >98.0% | 151.55 | C3H6ClN3O2 | 1g
1-Aminohydantoin hydrochloride is a major metabolite of Nitrofurantoin (HY-A0090) in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat milk et al 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of 1-Aminohydantoin hydrochloride before detection[1][2]
AdipoGen 2 7-Dichlorofluorescin DA
Chemical. CAS 4091-99-0. Formula C24H16Cl2O7. MW 487.29. Dichlorofluorescin diacetate H2DCFDA is a chemically reduced analog of fluorescein, used as an indicator for reactive oxygen species ROS in cells. The cell permeable non-fluorescent H2DCFDA is cleaved by cellular esterases and oxidation, and converted to the highly fluorescent 2,7-dichlorofluorescein. H2DCFDA might be reactive toward a broad range of oxidizing reactions that may be increased during intracellular oxidant stress. Peroxynitrite is an efficient mediator of this oxidation and neither NO, superoxide, nor hydrogen peroxide alone appear to oxidize DCFH. This probe is widely used to monitoring cellular redox processes. Used as a component/substrate of the 2,7-dichlorofluorescein diacetate DCFH-DA assay to quantitate reactive oxygen species ROS. Can detect reactive oxygen species in live cells. Spectral data lambdaEx=504nm/lambdaEm=529nm.
Medchemexpress LLC BMS-911172 10mg | 1644248-18-9 | 339.34 | C16H19F2N3O3 | 10 MG
BMS-911172 is a small-molecule inhibitor of adaptor-associated kinase 1 (AAK1) provided for laboratory research. It has reported nanomolar potency and is offered at high purity for biochemical and cellular studies.
- Selective AAK1 inhibition with nanomolar potency (IC50 ≈ 35 nM).
- High reported purity (≈99.5%).
- Molecular weight 339.34; formula C16H19F2N3O3.
- Soluble in DMSO; solution format available.
- Available in small-scale quantities suitable for research workflows.
- For research use only; not for clinical or human use.
Medchemexpress LLC BMS-911172 5mg | 1644248-18-9 | 5 MG
BMS-911172 is a small-molecule inhibitor of adaptor protein 2-associated kinase 1 (AAK1) supplied as a solid for laboratory research. It is brain-penetrant and reported to have low-nanomolar potency in biochemical and cellular assays (reported IC50 values ≈12-35 nM). For research use only.
- Potent AAK1 inhibitor with low-nanomolar activity.
- Brain-penetrant small molecule suitable for CNS-targeted studies.
- High purity (~99.5%) solid form for analytical and biological work.
- Supplied in a small quantity suitable for pilot or mechanistic studies.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC Gunagratinib | 2211082-53-8 | 98.5% | C22H25N5O4 | 10MG
Gunagratinib is a research small molecule that irreversibly and covalently inhibits fibroblast growth factor receptors (FGFR). It is orally active in preclinical models and is used in cancer research and biochemical studies; the molecule also contains an alkyne handle that allows copper-catalyzed azide-alkyne cycloaddition (click chemistry) applications.
Medchemexpress LLC C-021 | 864289-85-0 | 100.0% | 467.65 g/mol | C27H41N5O2 | 5 MG
C-021 is a small-molecule antagonist of the CC chemokine receptor 4 (CCR4) used for research into GPCR signaling and immunology. It inhibits CCR4-mediated chemotaxis in human and mouse systems and is supplied as a solid for laboratory studies.
- Target CCR4.
- Molecular formula C27H41N5O2.
- Molecular weight 467.65 g/mol.
- Purity 99.95%.
- Appearance solid, off-white to light yellow.
- Storage powder: -20°C (up to 3 years); in solvent: -80°C (short-term).
- Supplied in small research quantities.