Furans
Medchemexpress LLC 7-TFA-ap-7-Deaza-dA | 178420-75-2 | 98.8% | 399.32 | 50 MG
7-TFA-ap-7-Deaza-dA is a modified nucleoside that can be utilized in the synthesis of deoxyribonucleic acid or nucleic acid. It functions as a click chemistry reagent due to its Alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Modified nucleoside for nucleic acid synthesis
- Functions as a click chemistry reagent
- Contains an alkyne group for CuAAc reactions
- Related to nucleoside analogs and adenosine
- Applicable in cancer research and cell cycle/DNA damage studies
Medchemexpress LLC Selank diacetate 25mg | 25MG
Selank (Selanc) acetate is a synthetic peptide derived from tuftsin Selank acetate has anxiolytic activity and is a nootropic neuropsychotropic antidepressant and antistress compound[1
Alkali Scientific Nitrofurantoin, 5 G
Nitrofurantoin, 5g, is a laboratory-grade antibiotic used to study bacterial resistance, particularly in the context of urinary tract infections (UTIs). It is effective against a broad spectrum of Gram-positive and Gram-negative bacteria by disrupting their protein synthesis, DNA replication, and overall metabolism. The 5g quantity is ideal for use in antimicrobial susceptibility testing, such as Minimum Inhibitory Concentration (MIC) assays, disk diffusion, and other microbiological tests. Nitrofurantoin is also used in research settings to better understand antimicrobial resistance mechanisms, including the development of resistance in UTI pathogens.
Medchemexpress LLC BV02 | 292870-53-2 | MFCD00356631 | 99.8% | 377.36 | C20H15N3O5 | 50 MG
BV02 is a small-molecule research compound that inhibits 14-3-3 protein-protein interactions and has reported antibacterial activity. It modulates cell signaling by enhancing PARP and caspase-3 cleavage, and by inducing apoptosis and autophagy, making it useful for cellular and infection-related studies.
- Inhibits 14-3-3 protein-protein interactions.
- Induces apoptosis and autophagy in cell-based assays.
- Enhances PARP and caspase-3 cleavage.
- Shows reported antibacterial activity.
- Supplied at high purity suitable for research use.
- Available in solid and ready-to-use solution formats.
Medchemexpress LLC Trotabresib | 1706738-98-8 | 99.7% | 383.46 | 50 MG
Trotabresib (CC-90010) is a reversible and orally active BET inhibitor. It is used in the study of advanced solid tumors and inhibits the proliferation of diffuse midline glioma (DMG) cells.
- Reversible and orally active BET inhibitor
- Applied in the study for advanced solid tumors
- Inhibits proliferation of diffuse midline glioma (DMG) cells
- Exhibits stronger antitumor activity against H3K27M mutant DMG cells than DMG wildtype
Medchemexpress LLC DMA-135 hydrochloride | 2237925-62-9 | 98.0% | C16H18ClN7O | 50 MG
DMA-135 hydrochloride is an inhibitor targeting enterovirus 71 (EV71) IRES-dependent translation and replication. It binds to the EV71 SLII domain with moderately high affinity (KD= 520 nM) and shows no significant toxicity in cell-based studies. It induces conformational changes in the RNA structure and stabilizes the ternary complex DMA135-RNA-AUF1, inhibiting the translation and replication of EV71 with an IC50 of 7.54 μM.
- Targets enterovirus 71 (EV71) IRES-dependent translation and replication.
- Binds to the EV71 SLII domain with moderately high affinity.
- Induces conformational changes in RNA structure.
- Stabilizes the ternary complex DMA135-RNA-AUF1.
- Inhibits translation and replication of EV71 with an IC50 of 7.54 μM.
- Demonstrates no significant toxicity in cell-based studies.
Medchemexpress LLC SRI-37330 hydrochloride | 2322245-49-6 | 99.7% | 424.87 g/mol | C16H20ClF3N4O2S | 5 MG
SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor supplied as the hydrochloride salt for preclinical and biochemical research into metabolic disease and diabetes-related pathways. The compound is provided as a purified solid with solution formats available for assay use.
- Orally bioavailable TXNIP inhibitor suitable for metabolic research.
- Modulates glucagon secretion and reduces hepatic glucose production in models.
- Supplied as a hydrochloride salt to aid solubility and handling.
- High chemical purity (99.7%).
- Available in small milligram quantities and solution formats for assays.
- Documentation provided: datasheet and certificate of analysis.
Research Products International Corp Nitrofurantoin, 25 Grams
Nitrofurantoin works by inhibiting bacterial enzymes involved in the metabolism of certain compounds, leading to the disruption of bacterial DNA, RNA, and protein synthesis.
Researchers may use nitrofurantoin as a selective agent by incorporating it into culture media to promote the growth of cells or organisms that have been genetically engineered to express resistance to this antibiotic. It may have applications in microbiology and cell culture experiments, particularly in the context of antibiotic selection.
WARNING! This product can expose you to Nitrofurantoin, a chemical which is known to the State of California to cause developmental harm. For more information go to www.P65Warnings.ca.gov.
Apexbio Technology LLC CHLORHEXIDINE-DIACETATE-200MG
Chlorhexidine diacetate (CAS No 56-95-1) is a widely researched antimicrobial agent in the biomedical field known for its effectiveness against a broad spectrum of microorganisms Originating from its development as a potent disinfectant its mechanism of action involves disrupting bacterial cell membranes leading to cell death Its in vitro activity is often observed in the nanomolar to low micromolar range demonstrating strong efficacy at relatively low concentrations Chlorhexidine diacetate is commonly utilized in various experimental applications including cell culture studies animal model testing and drug screening assays In these contexts it serves as a benchmark for evaluating antimicrobial effectiveness or as a control compound in comparative studies Experimental concentrations typically depend on the specific research design Its widespread use underscores its importance in understanding microbial resistance and developing new antimicrobial strategies