Furans

Medchemexpress LLC Gunagratinib | 2211082-53-8 | 98.5% | C22H25N5O4 | 10MG

Gunagratinib is a research small molecule that irreversibly and covalently inhibits fibroblast growth factor receptors (FGFR). It is orally active in preclinical models and is used in cancer research and biochemical studies; the molecule also contains an alkyne handle that allows copper-catalyzed azide-alkyne cycloaddition (click chemistry) applications.

Medchemexpress LLC 7-tfa-ap-7-deaza-da | 178420-75-2 | 98.8% | C16H16F3N5O4 | 10MG

7-TFA-ap-7-Deaza-dA is a modified deoxynucleoside bearing a trifluoroacetyl-protected alkyne; designed for incorporation into DNA/oligonucleotides and for conjugation via copper-catalyzed azide-alkyne cycloaddition. Supplied as a solid or as a DMSO solution for use in synthetic and analytical workflows requiring a terminal alkyne handle.

• Contains an alkyne functional group for CuAAC click chemistry.
• Suitable for incorporation into deoxyribonucleic acid and oligonucleotide synthesis.
• Available as a solid and as a 10 mM solution in DMSO.
• High purity (~98.8%) suitable for research applications.
• Store solids at 4°C sealed; store solutions at low temperatures to preserve stability.

Medchemexpress LLC N-(3-(4-amino-7-(2-deoxy-pentofuranosyl)-prop-2-yn-1-yl)-2,2,2-trifluoroacetamide | 178420-75-2 | MFCD29904589 | 98.8% | 399.32 g·mol⁻¹ | C16H16F3N5O4 | 5 MG

7-TFA-ap-7-Deaza-dA is a modified deoxynucleoside that contains an alkyne functional group for bioorthogonal labeling. It is intended for incorporation into DNA or RNA and for conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC), supplied as a well-characterized solid or as a DMSO solution for synthesis and labeling workflows.

• High purity of 98.8% for reliable synthetic use.
• Alkyne handle enables CuAAC click chemistry conjugation.
• Compatible with DNA and RNA synthesis protocols.
• Available as solid or as 10 mM solution in DMSO for convenience.
• Characterized molecular weight and formula for analytical confirmation.

Medchemexpress LLC 2-Thiazolemethanol, α-[2-[1-(2-amino-5-chloro-4-pyrimidinyl)-2,3-dihydro-1H-indol-6-yl]ethynyl]-α-methyl | 1202764-53-1 | 99.4% | 50 MG

B022 is a potent, selective small-molecule inhibitor of NF-κB-inducing kinase (NIK) used for research applications; it contains an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (click chemistry) and is supplied as a solid with reported high purity.

• Potent, selective NIK inhibitor (Ki = 4.2 nM; IC50 ≈ 15.1 nM).
• Contains an alkyne group suitable for click chemistry (CuAAC).
• High reported purity (99.37%).
• Molecular weight 397.88; formula C19H16ClN5OS.
• Soluble in DMSO (250 mg/mL) with recommended formulation options for in vivo use.
• Stable when stored as powder at -20°C or 4°C per manufacturer guidance.

Medchemexpress LLC B022 | 1202764-53-1 | 99.4% | 10 MG

B022 is a potent, selective small-molecule inhibitor of NF-κB-inducing kinase (NIK) used for research into NF-κB signaling, inflammation, and cell death. The compound contains an alkyne group enabling click-chemistry conjugation and is supplied as a solid or as a DMSO solution for flexible experimental use.

• Potent NIK inhibition (Ki = 4.2 nM; IC50 = 15.1 nM).
• High purity suitable for biochemical and cellular assays.
• Contains an alkyne handle for copper-catalyzed azide-alkyne cycloaddition.
• Available as solid (multiple mg sizes) and as a 10 mM solution in DMSO.
• Stable when stored under recommended conditions (powder and solution storage guidelines).