Imidazopyridines
Medchemexpress LLC Elsulfavirine | 868046-19-9 | MFCD32215300 | 99.9% | 629.28 g·mol⁻¹ | C24H17BrCl2FN3O5S | 5 MG
Elsulfavirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) investigated for treatment of HIV-1. This listing is a research-grade reference compound supplied as a small solid amount for laboratory in vitro and in vivo studies; it is not intended for clinical use.
- Non-nucleoside reverse transcriptase inhibitor activity.
- Research-grade compound for laboratory use.
- High reported purity: 99.9%.
- Supplied as a 5 mg solid.
- Molecular weight approximately 629.28 g·mol⁻¹; formula C24H17BrCl2FN3O5S.
- Powder storage: -20°C; solution storage guidance available.
- Soluble in DMSO (~62.5 mg/mL); may require sonication.
- Not for human or veterinary use.
Medchemexpress LLC (R)-IL-17 modulator 4 | 2446804-29-9 | 99.6% | C27H34N6O2 | 10MG
(R)-IL-17 modulator 4 is a chiral small-molecule research compound used to modulate the IL-17 pathway in preclinical studies of inflammation, autoimmune conditions, infectious disease, and cancer. Supplied as an off-white to gray solid, it is characterized by high chemical purity and enantiomeric excess and is intended for laboratory research use.
- High purity (99.56%) and enantiomeric excess (96.58%).
- Molecular formula C27H34N6O2; molecular weight 474.60 Da.
- Off-white to gray solid appearance suitable for handling in research labs.
- Stable as a powder under recommended cold storage conditions.
- Available in multiple small pack sizes to support experimental workflows.
- Documentation available: data sheet, certificate of analysis, and SDS.
eMolecules 2231812-31-8 | Medchem Express | CXCR7 modulator 1 | 5mg | 533802261 | HY-107987 | 914.08 | C48H57F2N7O7S
ChemScene | 4-(Diphenylphosphino)phenol | 100mg | 785209944 | CS-0214442 | 5068-21-3 | MFCD00775358 | 278.291 | C18H15OP
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
Medchemexpress LLC SERABELISIB 10MG
Serabelisib (MLN1117) is a selective p110α inhibitor with an IC50 of 15 nM.Purity 99.66%.CAS 1268454-23-4
Medchemexpress LLC Cxcr7 antagonist-1 | 1613021-99-0 | 99.9% | 390.41 | 50 MG
CXCR7 antagonist-1 is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. It is useful in preventing tumor cell proliferation, tumor formation, inflammatory diseases, and many other diseases.
- Inhibits binding of SDF-1 (CXCL12) or I-TAC (CXCL11) to the chemokine receptor CXCR7.
- Useful in preventing tumor cell proliferation and formation.
- Applied in inflammatory diseases.
- Restores CXCL11 or RSV infection-induced β2-adrenergic receptor (β2AR) downregulation in infant airway smooth muscle cells.
- Inhibits airway smooth muscle relaxation induced by RSV-infection in BALB/c mouse models.
Medchemexpress LLC NOT Receptor Modulator 1 | 1015231-98-7 | 362.85 | 50 MG
NOT Receptor Modulator 1 is a nuclear receptor Nurr-1/NOT modulator. It was extracted from patent WO 2008034974 A1, Example 39 in table1.
- Purity: 98.61%
- Molecular weight: 362.85
- Chemical formula: C22H19ClN2O
- Appearance: White to off-white solid
- CAS number: 1015231-98-7
- Storage conditions: Powder: -20°C for 3 years, 4°C for 2 years. In solvent: -80°C for 6 months, -20°C for 1 month
- Solubility (in vitro): DMSO: 125 mg/mL (344.49 mM)
- Target: Nuclear receptor NOT (EC50 = 218 nM in CHO cells)
Medchemexpress LLC Cdk7-in-2 | 2326428-19-5 | 98.9% | 497.63 g/mol | C26H39N7O3 | 5 MG
CDK7-IN-2 is a selective small-molecule inhibitor of cyclin-dependent kinase 7 (CDK7) used for biochemical and cellular research. It exhibits potent CDK7 inhibitory activity and antiproliferative effects in cancer cell models, and is supplied for research use only.
- Selective CDK7 inhibitor suitable for biochemical and cellular assays.
- High reported purity (~98.9%) enabling reproducible results.
- Soluble in DMSO for convenient stock solution preparation.
- Suitable for in vitro cancer biology and transcriptional regulation studies.
- Provided in small research-friendly quantities for assay development.
- Intended for research use only; not for clinical or human use.
![Medchemexpress LLC 4-oxazolecarboxamide, N-[6-[(2-methoxyethyl)methylamino]-3-pyridinyl]-2-phenyl-5-(trifluoromethyl)- | 939375-07-2 | 99.9% | 420.39 g/mol | C20H19F3N4O3 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000330265.png-250.jpg)
Medchemexpress LLC 4-oxazolecarboxamide, N-[6-[(2-methoxyethyl)methylamino]-3-pyridinyl]-2-phenyl-5-(trifluoromethyl)- | 939375-07-2 | 99.9% | 420.39 g/mol | C20H19F3N4O3 | 10 MG
DGAT1-IN-3 is a potent, selective, and orally bioavailable small-molecule inhibitor of diacylglycerol O-acyltransferase 1 (DGAT-1) intended as a research reagent for studies of lipid metabolism, obesity, and related metabolic disorders.
- Potent DGAT-1 inhibition with human IC50 38 nM and rat IC50 120 nM.
- High purity as verified by LCMS (99.92%).
- Molecular formula C20H19F3N4O3 and molecular weight 420.39 g/mol.
- Suitable for in vitro and in vivo pharmacology studies of lipid metabolism.
- Available in small research quantities (1 mg, 5 mg, 10 mg).
- Structural formula and quality documentation provided in the product datasheet and COA.
Medchemexpress LLC BI-1622 | 2681392-19-6 | 99.0% | 508.53 | 5 MG
BI-1622 is an orally active, potent, and highly selective HER2 (ERBB2) inhibitor with an IC50 of 7 nM. It demonstrates over 25-fold selectivity for HER2 compared to EGFR. BI-1622 exhibits high antitumor efficacy in vivo in xenograft mouse tumor models using engineered H2170 and PC9 cells, and it possesses a favorable agent metabolism and pharmacokinetics profile.
- Inhibits proliferation of HER2-dependent cell lines.
- Induces a dose-dependent decrease in pHER2 and pERK levels.
- Displays good permeability and no PgP-mediated efflux liability.
- Shows good in vitro clearance in mouse liver microsomes and mouse hepatocytes.
- Potently inhibited the proliferation of cancer cell lines dependent on amplified HER2 or an NRG-1 fusion.
- Shows moderate clearance, a moderate volume of distribution, and good to moderate bioavailability up to 68%.
- Inhibits tumor growth and oncogenic signaling.
Medchemexpress LLC HY-15961 5mg Medchemexpress, Antitumor agent-3 CAS:420126-30-3 Purity:>98%
Medchemexpress, HY-15961 5mg Antitumor agent-3 CAS:420126-30-3 Antitumor agent-3 is a potent compound which comprises a new imidazopyridine having excellent antitumor activity as an active ingredient. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Cxcr7 antagonist-1 hydrochloride | 2990472-61-0 | 99.4% | 426.87 | 50 MG
CXCR7 antagonist-1 hydrochloride is a CXCR7 antagonist that inhibits the binding of SDF-1 chemokine (CXCL12) or I-TAC (CXCL11) to the chemokine receptor CXCR7.
- Useful in preventing tumor cell proliferation and formation
- Helps prevent inflammatory diseases
- Restores CXCL11 or RSV infection-induced β2-adrenergic receptor (β2AR) downregulation
- Inhibits RSV-infection induced airway smooth muscle relaxation in BALB/c mouse models
Medchemexpress LLC IL-17A modulator-1 | 2748749-29-1 | 98.80% | C33H31N5O4 | 50 MG
IL-17A modulator-1 is an IL-17A modulator extracted from patent WO2021239743+A1, specifically example 9. It functions by inhibiting the biological action of IL-17A, demonstrating a pIC50 of 8.2. This compound is intended for research purposes concerning diseases or disorders linked to the modulation of IL-17A activity.
- Inhibits the biological action of IL-17A
- Demonstrates a pIC50 of 8.2
- Suitable for research in immune component conditions and autoimmune pathologies
- Applicable for research in cancer and neurodegenerative disorders
- Appears as a white to off-white solid
eMolecules 1449779-49-0 | Medchem Express | DGAT1-IN-1 | 5mg | 446261225 | HY-12425 | MFCD28167832 | 551.566 | C30H28F3N3O4
Ambeed | H-Asn(Trt)-OtBu | 250mg | 600847672 | A779797 | 1998700-98-3 | MFCD30475843 | 430.548 | C27H30N2O3
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
Medchemexpress LLC HY-12813 5mg Medchemexpress, PDE10-IN-1 CAS:1516896-09-5 Purity:>98%
Medchemexpress, HY-12813 5mg PDE10-IN-1 CAS:1516896-09-5 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-13275 5mg Medchemexpress, IRAK inhibitor 1 CAS:1042224-63-4 Purity:>98%
Medchemexpress, HY-13275 5mg IRAK inhibitor 1 CAS:1042224-63-4 IRAK inhibitor 1 is a potent IRAK-4 inhibitor with IC50 of 216 nM, is poorly active against JNK-1 and JNK-2 with IC50 of 3.801 μM, and >10 μM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.