Imidazopyrimidines
Medchemexpress LLC 8-chloro caffeine | 4921-49-7 | MFCD00047246 | 99.4% | 228.64 g·mol⁻¹ | C8H9ClN4O2 | 100 MG
8-Chloro caffeine is a chlorinated derivative of the methylxanthine alkaloid caffeine that binds adenosine receptors (reported Ki = 30 μM). It is supplied as a white to off-white solid for laboratory research and includes documented physicochemical and storage recommendations.
- Binds adenosine receptors (reported Ki = 30 μM).
- Derivative of caffeine useful for receptor-binding and pharmacology studies.
- Molecular formula C8H9ClN4O2; molecular weight 228.64 g·mol⁻¹.
- High purity (approximately 99.4%).
- Solid, white to off-white appearance for easy handling.
- Store powder at -20°C for long-term stability; store in solvent at -80°C for up to 6 months.
Medchemexpress LLC 3-isobutyl-1-methylxanthine | 28822-58-4 | MFCD00005584 | 100.0% | 222.24 g/mol | C10H14N4O2 | 500MG
IBMX (3-isobutyl-1-methylxanthine) is a non-selective phosphodiesterase (PDE) inhibitor supplied as an analytical standard for research use. It increases intracellular cAMP and cGMP by inhibiting multiple PDE isoforms and is provided as a high-purity solid for laboratory applications. Reported IC50 values include 6.5 μM (PDE3), 26.3 μM (PDE4), and 31.7 μM (PDE5).
- Non-selective phosphodiesterase inhibitor.
- Modulates intracellular cAMP and cGMP levels.
- Useful for biochemical assays and cell-based studies.
- Provided as a high-purity analytical standard for research.
- Reported IC50s: PDE3 6.5 μM, PDE4 26.3 μM, PDE5 31.7 μM.
Medchemexpress LLC Theophylline impurity 9 | 42772-85-0 | 216.26 | C9H12O4S | 1 G
Theophylline impurity 9 is an analytical standard corresponding to an impurity of the drug theophylline, supplied for research and analytical applications. Consult the Certificate of Analysis for purity and recommended storage conditions.
- Analytical standard for theophylline impurity 9.
- Cas number 42772-85-0.
- Molecular formula C9H12O4S.
- Molecular weight 216.26.
- Refer to the certificate of analysis for purity and storage conditions.
- Packaged quantity: 1 G.
Medchemexpress LLC Xanthine oxidase, Microorganism | 9002-17-9 | ≥10 U/mg solid | 283 kDa | 100 U
Xanthine oxidase, Microorganism (XO) is a xanthine oxidoreductase enzyme that generates reactive oxygen species (ROS). It catalyzes the oxidation of hypoxanthine to xanthine, and further catalyzes the oxidation of xanthine to uric acid. This product is for research use only.
- Generates reactive oxygen species (ROS)
- Catalyzes oxidation of hypoxanthine to xanthine
- Catalyzes oxidation of xanthine to uric acid
- Rapidly and completely depletes hypoxanthine in human erythrocytes
- Inhibits growth of Plasmodium falciparum in human erythrocytes in vitro
- Reduces viability of postnatal cerebellar granule neurons
- Optimal pH is 7.5-8.0
- Soluble in water at 10 mg/mL or higher
Medchemexpress LLC Xanthine Oxidase Antibody (YA1957) | 100 UL
Xanthine Oxidase Antibody (YA1957) is a rabbit-derived, non-conjugated IgG monoclonal antibody, specifically designed to target Xanthine Oxidase. This antibody is characterized by a predicted and observed molecular weight of 146 kDa, making it suitable for various research applications requiring specific detection of Xanthine Oxidase.
- Rabbit-derived, non-conjugated IgG monoclonal antibody
- Targets Xanthine Oxidase
- Predicted and observed molecular weight of 146 kDa
- Suitable for Western Blot (WB) and Immunohistochemistry-Paraffin (IHC-P) experiments
- Validated for use in human, mouse, and rat samples
Medchemexpress LLC BioE-1115 | 1268863-35-9 | 98.2% | 10 MG
BioE-1115 is a highly selective and potent PAS kinase (PASK) inhibitor with an IC50 of ~4 nM. It also acts as a potent casein kinase 2α inhibitor with an IC50 of ~10 μM.
- Highly selective PASK inhibitor (IC50 ~4 nM).
- Potent casein kinase 2α inhibitor (IC50 ~10 μM).
- Induces dose-dependent loss of PASK phosphorylation in HEK293 cells.
- Reduces SREBP activity in HepG2 cells without affecting cell morphology or growth.
- Suppresses SREBP-1c target gene expression and SREBP-1 maturation in liver in vivo.
- Decreases insulin resistance, hepatic/serum triglycerides, and serum glucose dose-dependently.
- Does not cause significant changes in liver or body weight.
eMolecules 93778-15-5 | 2,3-dihydroxypropyl 4-hydroxybenzoate | Toronto Research Chemicals | MFCD21608153 | 212.201 | C10H12O5OCC(O)COC(=O)c1ccc(O)cc1 | 50mg | 601594345
2,3-dihydroxypropyl 4-hydroxybenzoate | Toronto Research Chemicals | 93778-15-5 | MFCD21608153 | 212.201 | C10H12O5OCC(O)COC(=O)c1ccc(O)cc1 | 50mg | 601594345
Medchemexpress LLC 3-Methylxanthine | 1076-22-8 | 99.5% | C6H6N4O2 | 100 G
3-Methylxanthine is a xanthine derivative that acts as a cyclic guanosine monophosphate (GMP) inhibitor, with an IC50 of 920 μM on guinea-pig isolated trachealis muscle. This product is intended for research use only.
- Stable under recommended storage conditions
- Recommended storage for powder at -20°C for 3 years or 4°C for 2 years
- Recommended storage in solvent at -80°C for 6 months or -20°C for 1 month
Selleck Chemical LLC 3-Methylxanthine
3-Methylxanthine (3-MX) a 3-alkylxanthine is an inhibitor of cyclic guanosine monophosphate (GMP) phosphodiesterase (PDE) with IC50 of 920 M on guinea-pig isolated trachealis muscle
eMolecules 58-08-2 | Caffeine | Chem-Impex | MFCD00005758 | 194.194 | C8H10N4O2 | 99.000 | Cn1cnc2n(C)c(=O)n(C)c(=O)c12 | 250g | 490848234
Caffeine | Chem-Impex | 58-08-2 | MFCD00005758 | 194.194 | C8H10N4O2 | 99.000 | Cn1cnc2n(C)c(=O)n(C)c(=O)c12 | 250g | 490848234
Apexbio Technology LLC XAC 96865-92-8 5mg
XAC is a small-molecule antagonist targeting adenosine receptors It is designed to competitively inhibit the binding of adenosine to its receptors thereby modulating receptor-mediated signaling pathways XAC exerts its biological activity primarily through interference with adenosine-induced signaling Experimental studies indicate that XAC inhibits adenosine-induced cellular processes such as neurotransmission modulation and cardiovascular responses Based on these pharmacological properties XAC holds research potential in neuroscience and cardiovascular physiology to investigate adenosine-mediated signaling pathways in specific cellular events and physiological conditions
TARGETMOL CHEMICALS INC XANTHINE OXIDASE-IN-1 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Xanthine oxidase-IN-1 is a useful organic compound for research related to life sciences. The catalog number is T10509 and the CAS number is 1071970-13-2. purity: 99%
Sigma Aldrich Fine Chemicals Biosciences Theophylline Related Compo25MG
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
Medchemexpress LLC HY-B1505 100mg Medchemexpress, Acefylline CAS:652-37-9 Purity:>98%
Medchemexpress, HY-B1505 100mg Acefylline CAS:652-37-9 Acefylline is an adenosine receptor antagonist. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Racemic lisofylline | 6493-06-7 | MFCD00871850 | 98.6% | 280.33 g/mol | C13H20N4O3 | 50MG
Racemic lisofylline is the racemate of lisofylline, an anti-inflammatory research compound and a metabolite-derived analogue of pentoxifylline. It is used in biochemical and cellular studies for its inhibition of phosphatidic acid and free fatty acid generation, and is supplied as a high-purity solid for research applications.
- Purity 98.6%.
- Molecular weight 280.33 g/mol.
- Molecular formula C13H20N4O3.
- Available in small quantities including 50 mg.
- Used in studies of inflammation and oxidative tissue injury.
- Supplied as a solid powder for biochemical assays.