Imidazopyrimidines
6-Mercaptopurine Monohydrate 98.0+%, TCI America™
CAS: 6112-76-1 Molecular Formula: C5H6N4OS Molecular Weight (g/mol): 170.19 MDL Number: MFCD03854445,MFCD01461928 InChI Key: WFFQYWAAEWLHJC-UHFFFAOYSA-N Synonym: 6-mercaptopurine monohydrate,6-mercaptopurine hydrate,mercaptopurine monohydrate,mercaptopurine hydrate,6h-purine-6-thione, 1,7-dihydro-, monohydrate,6,7-dihydro-3h-purine-6-thione hydrate,purine-6-thiol monohydrate,1,7-dihydro-6h-purine-6-thione monohydrate,purine-6-thiol, monohydrate,unii-e7wed276i5 PubChem CID: 2724350 ChEBI: CHEBI:31822 IUPAC Name: 6,7-dihydro-3H-purine-6-thione hydrate SMILES: O.S=C1N=CNC2=C1NC=N2
Chem-Impex International, Inc. 6-Mercaptopurine monohydrate | 6112-76-1 | MFCD01461928 | 100G
6-Mercaptopurine monohydrate, 6112-76-1, MFCD01461928, 100G
Medchemexpress LLC 6-Mercaptopurine hydrate | 6112-76-1 | 99.9% | 170.19 | 1 ML
6-Mercaptopurine hydrate is a purine analogue that acts as an antagonist of endogenous purines. It has been widely used as an antileukemic and immunosuppressive agent. This product is for research use only.
- Purine analogue
- Acts as an antagonist of endogenous purines
- Used as an antileukemic agent
- Used as an immunosuppressive agent
Medchemexpress LLC 6-Mercaptopurine hydrate | 6112-76-1 | 99.9% | 170.19 | 100 MG
6-Mercaptopurine hydrate is a purine analogue that acts as an antagonist of endogenous purines. It has been widely used as an antileukemic and immunosuppressive agent.
- Purine analogue.
- Antagonist of endogenous purines.
- Induces NR4A3 transcriptional activity 1.6- to 11-fold in a dose-responsive manner.
- Leads to a dose-dependent increase in NR4A3 protein levels.
- Increases cell surface GLUT4 in both basal cells (1.8- to 3.6-fold) and insulin-stimulated cells (2.9- to 4.4-fold) over controls.
- Increases phospho-AS160 significantly in a dose-responsive manner under both basal and insulin-stimulated conditions.
- Induces cell cycle arrest and apoptosis of neural progenitor cells in the developing fetal rat brain.
- Purity: 99.9%.
- Appearance: Solid.
- Color: Light yellow to yellow.
- Used as an antileukemic agent.
- Used as an immunosuppressive agent.
Medchemexpress LLC 6H-Purine-6-thione, 1,2,3,9-tetrahydro-, hydrate (1:1) | 6112-76-1 | 99.9% | 170.19 | 500 MG
6-Mercaptopurine hydrate is a purine analogue that acts as an antagonist of endogenous purines. It has been widely used as an antileukemic agent and immunosuppressive agent.
- Induces NR4A3 transcriptional activity.
- Increases NR4A3 protein levels.
- Increases cell surface GLUT4 in basal and insulin-stimulated cells.
- Increases phospho-AS160.
- Significantly inhibits EcSTH-induced phosphorylation of AMPK and ACC1.
- Promotes an increase in S phase cell population in fetal telencephalons.
- Promotes an increase in G2/M phase cell population in fetal telencephalons.
- Increases sub-G1 phase cell population (apoptotic cells).
- Inhibited expression of CAV1 protein in MM1S cells.
- Further promoted bortezomib-mediated survival of MM-bearing mice.
Medchemexpress LLC 6-mercaptopurine hydrate | 6112-76-1 | MFCD03854445 | 99.9% | 170.19 g/mol | C5H6N4OS | 5 MG
6-mercaptopurine hydrate is the hydrated form of the purine analogue 6-mercaptopurine, used in research as an inhibitor of purine metabolism and as a reference compound in biochemical and pharmacological assays.
- Hydrated purine analogue; CAS 6112-76-1.
- Molecular formula C5H6N4OS and molecular weight 170.19 g/mol.
- High purity (99.9% by HPLC) suitable for analytical use.
- Solid monohydrate form with consistent batch characterization.
- Commonly used in in vitro and in vivo pharmacology and biochemical assays.
- Supplied in small research pack sizes for laboratory applications.
Sigma Aldrich 6-Mercaptopurine monohydrate
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Research Products International Corp 6-Mercaptopurine, 10 Grams
Analog of the natural purines hypoxanthine and adenine. Antineoplastic agent which acts as an antimetabolite. Toxicity: LD50 < 364 mg/kg.
WARNING! This product can expose you to 6-Mercaptopurine hydrate, a chemical which is known to the State of California to cause developmental harm. For more information go to www.P65Warnings.ca.gov.
Research Products International Corp 6-Mercaptopurine, 5 Grams
Analog of the natural purines hypoxanthine and adenine. Antineoplastic agent which acts as an antimetabolite. Toxicity: LD50 < 364 mg/kg.
WARNING! This product can expose you to 6-Mercaptopurine hydrate, a chemical which is known to the State of California to cause developmental harm. For more information go to www.P65Warnings.ca.gov.
Medchemexpress LLC 3-Methylxanthine | 1076-22-8 | 99.5% | C6H6N4O2 | 100 G
3-Methylxanthine is a xanthine derivative that acts as a cyclic guanosine monophosphate (GMP) inhibitor, with an IC50 of 920 μM on guinea-pig isolated trachealis muscle. This product is intended for research use only.
- Stable under recommended storage conditions
- Recommended storage for powder at -20°C for 3 years or 4°C for 2 years
- Recommended storage in solvent at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC 2-hydroxyethyl 4-methylbenzenesulfonate | 42772-85-0 | 216.26 | C9H12O4S | 500 MG
Theophylline impurity 9 (2-hydroxyethyl 4-methylbenzenesulfonate) is an analytical reference standard used for identification and quantification of a theophylline-related impurity in research and quality-control workflows.
- Analytical reference standard for theophylline impurity identification.
- Cas 42772-85-0.
- Molecular formula C9H12O4S; molecular weight 216.26 g/mol.
- Available pack sizes include 100 mg, 250 mg, 500 mg, and 1 g; larger sizes by inquiry.
- Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Batch-specific purity and analytical data provided in the certificate of analysis.
Medchemexpress LLC Adenine monohydrochloride hemihydrate | 6055-72-7 | MFCD11046306 | 99.9% | 189.60 | C5H8ClN5O | 1 ML
Adenine monohydrochloride hemihydrate is the hydrochloride salt (hemihydrate) of adenine, supplied as a solid or as a pre-made 10 mM solution in DMSO. It is used as a biochemical reagent and nucleobase source in molecular biology and biochemical assays, and is provided with supporting analytical documentation for quality control.
- High purity (99.87%) for reliable analytical results.
- Available as solid and 10 mM solution in DMSO for experimental flexibility.
- White to off-white solid, easy to handle and store.
- Supplied with COA, SDS, HPLC, and MS documentation for verification.
- Store at 4°C and protect from light; solutions: -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC 3-isobutyl-1-methylxanthine | 28822-58-4 | MFCD00005584 | 100.0% | 222.24 | C10H14N4O2 | 25MG
IBMX (3-Isobutyl-1-methylxanthine) is a broad-spectrum phosphodiesterase (PDE) inhibitor used as a research reagent to elevate intracellular cyclic nucleotides by inhibiting multiple PDE isoforms. It is supplied as a stable solid with documented physicochemical, purity, and solubility data for preparation of in vitro and in vivo formulations.
- Broad-spectrum PDE inhibitor with reported IC50s of 6.5 μM (PDE3), 26.3 μM (PDE4), and 31.7 μM (PDE5).
- Molecular formula C10H14N4O2; molecular weight 222.24 g/mol.
- High purity suitable for research (reported purities ~99.97-99.99%).
- Soluble in DMSO (125 mg/mL) and compatible with published in vivo cosolvent formulations.
- Available in multiple solid pack sizes, including 25 MG, for assay preparation.
- Recommended storage: powder -20°C (short term refrigerated at 4°C), in solvent -80°C for long term.