Lactams
Apexbio Technology LLC Sulbactam sodium,100mg CAS# 69388-84-7
Sulbactam sodium. Other sizes are also available. Please inqury us for quote.
Apexbio Technology LLC Sulbactam 68373-14-8 100mg
Sulbactam (CAS 68373-14-8) is a small-molecule inhibitor targeting bacterial -lactamase enzymes It is designed to inhibit -lactamase-mediated hydrolytic inactivation of -lactam antibiotics thereby enhancing antibiotic stability and efficacy Sulbactam exerts its biological activity primarily through competitive irreversible inhibition by covalently binding to the -lactamase active site Experimental studies report an IC50 value in the low micromolar range for inhibition of various bacterial -lactamase enzymes Based on these pharmacological properties Sulbactam holds research potential in investigating resistance mechanisms to -lactam antibiotics assessing combined therapeutic regimens and exploring novel clinical strategies for infections caused by -lactamase-producing pathogens
Medchemexpress LLC Sulbactam sodium | 69388-84-7 | 99.41% | 100 MG
Sulbactam sodium is an analytical standard intended for research and analytical applications. It functions as a competitive, irreversible beta-lactamase inhibitor and demonstrates antimicrobial activity against multidrug-resistant Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex. This compound serves as a reference for assays and is commonly used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Analytical standard for research and analytical applications
- Competitive, irreversible beta-lactamase inhibitor
- Antimicrobial activity against multidrug-resistant (MDR) Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex
- Used in HPLC, GC, and MS experiments
Medchemexpress LLC Sulbactam sodium | 69388-84-7 | 99.4% | 50 MG
Sulbactam sodium (Standard) is an analytical standard intended for research and analytical applications. It functions as a competitive, irreversible beta-lactamase inhibitor, demonstrating antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex.
- Used as a reference standard for assays
- Competitive, irreversible beta-lactamase inhibitor
- Shows antimicrobial activity against multidrug-resistant acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex
- Utilized in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
Selleck Chemical LLC Tazobactam Sodium-E0167-5MG
Tazobactam (Tazobactam acid Tazobactamum) Sodium is a beta-lactamase inhibitor that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms
Apexbio Technology LLC Tazobactam (sodium salt) 89785-84-2 500mg
Tazobactam sodium salt (CAS 89785-84-2) is a small-molecule inhibitor targeting -lactamases It is designed to irreversibly bind to -lactamases thereby preventing the enzyme-mediated hydrolysis of -lactam antibiotics Tazobactam sodium salt exerts its biological activity primarily through -lactamase inhibition In microbiological assays tazobactam demonstrates intrinsic antibacterial activity against several Acinetobacter strains typically with MIC values of 8 mg/L (range 2 32 mg/L) Based on these pharmacological properties tazobactam sodium salt holds research potential in microbiological assessments and efficacy evaluations of -lactam antibiotic combinations
Medchemexpress LLC 5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione | 26166-92-7 | MFCD30188073 | 97.0% | 337.13 | C13H9BrN2O4 | 25 MG
Thalidomide-5-Br (5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione) is a brominated thalidomide derivative supplied as a research reagent and used in studies of inflammation, tumor biology, and neurology.
- contains a brominated thalidomide core
- used in inflammation research
- applicable to tumor biology studies
- suitable for neurology research
- available in small research quantities
Medchemexpress LLC Thalidomide-NH-C10-COOH | 2428400-33-1 | 97.5% | 250 MG
Thalidomide-NH-C10-COOH is a synthesized E3 ligase ligand-linker conjugate. It incorporates a Thalidomide based CRBN ligand and a linker used in PROTAC technology. With a molecular weight of 457.52 and formula C24H31N3O6, this compound appears as a light yellow to yellow solid. It is intended for research use only.
- Targets cereblon.
- Recommended storage for powder is -20°C for 3 years or 4°C for 2 years.
- When in solvent, store at -80°C for 6 months or -20°C for 1 month.
- Part of PROTAC technology.
Medchemexpress LLC Thalidomide-NH-C6-NH2 TFA | 2093386-51-5 | 99.8% | 1 G
Thalidomide-NH-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate, incorporating a Thalidomide-based cereblon ligand and a linker used in PROTAC technology. This compound is characterized by its high purity of 99.8%.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates Thalidomide-based cereblon ligand
- Features a linker used in PROTAC technology
- Designed for use in PROTACs that exploit the intracellular ubiquitin-proteasome system
Medchemexpress LLC Thalidomide-5-O-C6-NH2 hydrochloride | 2761398-05-2 | 409.86 | C19H24ClN3O5 | 10 MG
Thalidomide-5-O-C6-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand used as an E3 ligase recruiting moiety in PROTAC development and chemical biology research. The compound contains a six-carbon linker terminating in a primary amine and is supplied as the hydrochloride salt to aid handling and stability for research applications.
- Used as a cereblon ligand to recruit CRBN in PROTAC and degrader design.
- Contains a C6 linker with a terminal amine for conjugation to linkers or target ligands.
- Provided as a hydrochloride salt for improved handling and solubility.
- Solid form suitable for storage under recommended conditions.
- Intended for research use; consult vendor documentation or COA for purity and analytical data.
Medchemexpress LLC Thalidomide-NH-amido-PEG4-C2-NH2 hydrochloride | 2983037-00-7 | >98.0% | 586.03 | 25 MG
Thalidomide-NH-amido-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate. It integrates a thalidomide-based cereblon ligand with a linker, making it suitable for applications in PROTAC technology. This compound is intended for research purposes only and is not for sale to patients.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates thalidomide-based cereblon ligand
- Utilizes a linker for PROTAC technology applications
- Suitable for research use
Medchemexpress LLC Thalidomide-NH-PEG3-COOH | 2375283-62-6 | 98.9% | 477.46 | 25 MG
Thalidomide-NH-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate. It incorporates the Thalidomide-based cereblon ligand and a linker utilized in PROTAC technology. PROTACs (Proteolysis Targeting Chimeras) are designed with two different ligands connected by a linker, enabling the selective degradation of target proteins.
- Incorporates Thalidomide-based cereblon ligand
- Utilizes a linker for PROTAC technology
- Designed for selective degradation of target proteins
- For research use only
Medchemexpress LLC 2,6-piperidinedione, 3-(1,3-dihydro-5-iodo-1-oxo-2h-isoindol-2-yl)- | 2291364-01-5 | MFCD32853043 | 98.0% | 370.14 g/mol | C13H11IN2O3 | 25 MG
Deoxy-thalidomide-5-iodine is a thalidomide analog bearing an iodine substituent at the 5-position used as a cereblon-binding ligand in PROTAC and targeted protein degradation research. Supplied as a colored solid with high reported purity, it is intended for chemical biology and linker-conjugation workflows.
- Thalidomide-derived cereblon ligand suitable for PROTAC design.
- High reported purity (98.0% by NMR) for research applications.
- Blue to blue-green solid physical form for easy handling.
- Molecular formula C13H11IN2O3 and molecular weight 370.14 g/mol.
- Suitable for linker attachment and synthesis of bifunctional degraders.
Medchemexpress LLC Thalidomide-pinacolborane | 2229725-98-6 | N/A | 97.0% | 384.19 g/mol | C19H21BN2O6 | 5 MG
Thalidomide-pinacolborane is a thalidomide analogue bearing a pinacolborane (Bpin) group, used as a synthetic intermediate and as a ligand for E3 ligase in PROTAC research. Molecular formula C19H21BN2O6, molecular weight 384.19 g/mol. Manufacturer documentation lists CAS 2229725-98-6 and purity 97.0%. Recommended storage is -20°C under nitrogen; in solvent, -80°C (up to 6 months) or -20°C (up to 1 month) under nitrogen.
- Functionalized thalidomide analogue useful as a synthetic intermediate.
- Serves as a ligand for E3 ligase in PROTAC applications.
- High purity (97.0%) suitable for research use.
- Stable when stored under nitrogen at recommended temperatures.
- Available in small research sizes down to 5 mg.