Lactams
Selleck Chemical LLC Tazobactam S3077-500mg
Tazobactam (Tazobactam acid Tazobactamum) is a -lactamases Inhibitor with antibacterial activity It also inhibits the class D oxacillinase OXA-2 It is used in combination with piperacillin and other -lactam antibiotics to broaden their spectrum and enhance their effect
![eMolecules 16084-57-4 | 3-Azabicyclo[3.2.0]heptane hydrochloride | Synthonix | MFCD22573703 | 133.620 | C6H12ClN | 97.000 | Cl.C1CC2CNCC12 | 1g | 532174148](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000472055.jpg-250.jpg)
eMolecules 16084-57-4 | 3-Azabicyclo[3.2.0]heptane hydrochloride | Synthonix | MFCD22573703 | 133.620 | C6H12ClN | 97.000 | Cl.C1CC2CNCC12 | 1g | 532174148
3-Azabicyclo[3.2.0]heptane hydrochloride | Synthonix | 16084-57-4 | MFCD22573703 | 133.620 | C6H12ClN | 97.000 | Cl.C1CC2CNCC12 | 1g | 532174148
Apexbio Technology LLC Sulbactam sodium,100mg CAS# 69388-84-7
Sulbactam sodium. Other sizes are also available. Please inqury us for quote.
Medchemexpress LLC Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride | 2341841-02-7 | 99.3% | 410.81 | 100 MG
Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, along with a linker. This compound is instrumental in designing PROTACs, which are molecules engineered to degrade specific target proteins. It functions by recruiting the E3 ubiquitin ligase to the target protein, leading to its ubiquitination and subsequent proteasomal degradation.
- Includes a ligand for an E3 ubiquitin ligase.
- Features a linker component.
- Used for the development of protein degraders.
- Purity of 99.30%.
- Available in solid form, white to off-white in color.
- Suitable for research purposes.
Medchemexpress LLC Thalidomide-O-C4-COOH | 2169266-67-3 | 97.0% | 1 G
Thalidomide-O-C4-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. It is for research use only and not intended for sale to patients.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates thalidomide based cereblon ligand
- Used in PROTAC technology
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Thalidomide-PEG2-C2-NH2 (TFA) | 2097509-36-7 | 99.1% | 50 MG
Thalidomide-PEG2-C2-NH2 (TFA) is a chemical compound characterized by its solid, light yellow to yellow appearance. With a molecular weight of 518.44 and a high purity of 99.1% (HPLC), this product is designated for laboratory chemical applications, substance manufacturing, and general research purposes. It requires specific storage conditions to ensure its stability and effectiveness.
- High purity (99.1% by HPLC)
- Solid form
- Suitable for laboratory chemical and research applications
- Requires cold storage to maintain integrity
Medchemexpress LLC Thalidomide-O-C6-NHBoc | 2509093-23-4 | 95.99% | C24H31N3O7 | 100 MG
The product "Thalidomide-O-C6-NHBoc" is an E3 ligase ligand-linker conjugate. It is designed for use in PROTAC technology and incorporates a thalidomide-based cereblon ligand with a linker. It is intended for research use only and has a purity of 95.99%.
Features and benefits:
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates a cereblon ligand
- Used in PROTAC technology
- Purity of 95.99%
- Available in various quantities for research needs
- Includes data sheet, COA, SDS, and handling instructions
- Soluble in DMSO
- Storage at -20°C (1 month) or -80°C (6 months) in solvent
Medchemexpress LLC Thalidomide-NH-C10-COOH | 2428400-33-1 | 97.5% | 250 MG
Thalidomide-NH-C10-COOH is a synthesized E3 ligase ligand-linker conjugate. It incorporates a Thalidomide based CRBN ligand and a linker used in PROTAC technology. With a molecular weight of 457.52 and formula C24H31N3O6, this compound appears as a light yellow to yellow solid. It is intended for research use only.
- Targets cereblon.
- Recommended storage for powder is -20°C for 3 years or 4°C for 2 years.
- When in solvent, store at -80°C for 6 months or -20°C for 1 month.
- Part of PROTAC technology.
Medchemexpress LLC Thalidomide-4-O-C12-NH2 hydrochloride | 95.6% | 494.02 | C25H36ClN3O5 | 10 MG
Thalidomide-4-O-C12-NH2 hydrochloride is a thalidomide-derived cereblon ligand provided as the hydrochloride salt for use in chemical biology and medicinal chemistry applications. It functions as a CRBN E3 ligase recruiter for targeted protein degradation and is intended for use in PROTAC and ligand-linker conjugation studies. Store protected from light at recommended temperatures.
Medchemexpress LLC Thalidomide-4-O-C10-NH2 hydrochloride | 95.6% | 465.97 | C23H32ClN3O5 | 5 MG
Thalidomide-4-O-C10-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand provided as a hydrochloride salt for use in PROTAC construction and chemical biology research. Supplied as a research reagent, it is intended for laboratory applications and not for human use.
- Cereblon ligand suitable for E3 ligase recruitment in PROTACs and degrader design.
- Hydrochloride salt improves solubility and handling compared with the free base.
- Reported purity approximately 95.6% as supplied.
- Molecular formula C23H32ClN3O5 and molecular weight 465.97.
- Available in small research pack sizes, for example 5 mg.
Medchemexpress LLC Deoxy-thalidomide-5-iodine | 2291364-01-5 | MFCD32853043 | 98.0% | 370.14 g/mol | C13H11IN2O3 | 250 MG
Deoxy-thalidomide-5-iodine is a thalidomide analog used as a cereblon-binding ligand in targeted protein degradation and PROTAC research. It is provided as a characterized small-molecule building block suitable for conjugation in bifunctional degrader synthesis and related chemical biology applications.
- Used as cereblon-binding ligand for PROTAC development.
- High reported purity: 98.0% (NMR).
- Molecular weight 370.14 g/mol and formula C13H11IN2O3.
- Solid; store at 4°C and protect from light.
- Available in multiple package sizes, including 250 mg.
Medchemexpress LLC Thalidomide-NH-PEG3-COOH | 2375283-62-6 | 98.9% | 477.46 | 25 MG
Thalidomide-NH-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate. It incorporates the Thalidomide-based cereblon ligand and a linker utilized in PROTAC technology. PROTACs (Proteolysis Targeting Chimeras) are designed with two different ligands connected by a linker, enabling the selective degradation of target proteins.
- Incorporates Thalidomide-based cereblon ligand
- Utilizes a linker for PROTAC technology
- Designed for selective degradation of target proteins
- For research use only
Medchemexpress LLC Thalidomide 4-fluoride (Cereblon ligand 4) | 835616-60-9 | 99.83% | 276.22 | 25 G
Thalidomide 4-fluoride (Cereblon ligand 4) is a Thalidomide-based Cereblon ligand that is utilized in the recruitment of the CRBN protein. It can be linked to the ligand for IRAK4 protein via a linker to form PROTAC IRAK4 degrader-1. It is for research use only and not sold to patients.
- Purity: 99.83%
- Molecular weight: 276.22
- Formula: C13H9FN2O4
- CAS No.: 835616-60-9
- Appearance: Solid
- Color: Off-white to gray
- Solubility (in vitro): DMSO : 200 mg/mL (724.05 mM; requires ultrasonic; hygroscopic DMSO impacts solubility, use newly opened DMSO)
- Storage (powder): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 2 years, -20°C for 1 year