Lactams
Medchemexpress LLC Thalidomide-NH-amido-PEG4-C2-NH2 hydrochloride | 2983037-00-7 | 98.01% | 586.03 | 50 MG
Thalidomide-NH-amido-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand. It is used in PROTAC technology, which exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Incorporates Thalidomide based cereblon ligand
- Used in PROTAC technology
- Targets E3 ubiquitin ligase
- Facilitates selective degradation of target proteins
TARGETMOL CHEMICALS INC S-THALIDOMIDE 5MG
Also available in 10mg 25mg 50mg 100mg 500mg and bulk. Please contact Fisher for quotes. (S)-Thalidomide ((S)-(-)-Thalidomide) is the S-isomer of Thalidomide with immunomodulatory anti-inflammatory anticancer anti-angiogenic and pro-apoptotic activities and is used in the study of leprosy erythema nodosum and myeloma. purity: 99%
Medchemexpress LLC VH 101 phenol-alkylC4-amine dihydrochloride | 2564467-03-2 | 676.67 | 25 MG
VH 101 phenol-alkylC4-amine dihydrochloride is a von-Hippel-Lindau protein ligand (VHL). It incorporates an E3 ligase ligand and an alkylC4 linker.
- Von-Hippel-Lindau protein ligand (VHL)
- Incorporates an E3 ligase ligand
- Incorporates an alkylC4 linker
- Can be used for PROTAC research (extracted from patent WO2022051326A1)
Medchemexpress LLC Thalidomide-1-Me,4-OH | 2244568-06-5 | >98.0% | 288.26 | C14H12N2O5 | 25 MG
Thalidomide-1-Me,4-OH is a thalidomide analogue with a 1-methyl and 4-hydroxyl substitution that functions as an E3 ubiquitin ligase ligand. It is used in biochemical research to recruit E3 ligases (Cereblon-related activity) for targeted protein degradation studies.
- Acts as an E3 ligase ligand suitable for cereblon-mediated recruitment.
- Contains 1-methyl and 4-hydroxyl substitutions on the thalidomide scaffold.
- Molecular formula C14H12N2O5, molecular weight 288.26.
- Purity greater than 98%.
- Recommended storage: powder at -20°C (long-term) or 4°C (short-term); in solvent at -80°C for extended storage.
- Supplied in small research quantities, e.g., 25 MG, for biochemical assays.
Medchemexpress LLC Recombinant human 14-3-3 epsilon protein, GST-tagged | >95.0% | 100 UG
Recombinant human 14-3-3 epsilon protein with an N-terminal GST tag supplied as a lyophilized powder. The product contains full-length human YWHAE sequence (M1-Q255) expressed in E. coli, intended for research use. It is provided with low endotoxin and high purity for biochemical and cell-based assays and should be stored frozen and reconstituted per the supplier recommendations.
Medchemexpress LLC 14-3-3 epsilon Antibody (YA2629) | 100 UL
The 14-3-3 epsilon antibody (YA2629) is a rabbit-derived, non-conjugated IgG monoclonal antibody designed to target the 14-3-3 epsilon protein. This protein acts as an adapter involved in the regulation of diverse cellular signaling pathways by binding to phosphoserine or phosphothreonine motifs, thereby modulating the activity of binding partners. The antibody shows reactivity with human, mouse, and rat samples and is supplied as a liquid formulation.
- Reactivity with human, mouse, and rat samples
- Suitable for WB, IHC-P, ICC/IF, and FC applications
- Formulated in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide, and 0.05% BSA
- Store at -20°C for 1 year
- Avoid repeated freeze/thaw cycles
- Shipping with blue ice
Medchemexpress LLC Thalidomide-5-Br | 26166-92-7 | 98.4% | 337.13 g/mol | C13H9BrN2O4 | 50 MG
Thalidomide-5-Br is a brominated thalidomide analogue supplied for biochemical research. It has a reported molecular weight of 337.13 g/mol and is supplied as an off-white to gray solid with reported purity around 98%.
- Used in research of inflammation, tumor biology, and neurology.
- Supplied as a solid suitable for formulation or dissolution in solvent for experimental use.
- Reported high purity for analytical and preclinical studies.
- Stable at room temperature for extended storage; in-solution storage requires low temperatures.
TARGETMOL CHEMICALS INC Thalidomide-O-amido-C4-N3 10MG
Also available in 1 mL, 2 mg, 5 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes.Thalidomide-O-amido-C4-N3 (Cereblon Ligand-Linker Conjugates 4) is an E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and a linker. Purity 97.01%
Medchemexpress LLC 5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione | 26166-92-7 | MFCD30188073 | 98.4% | 337.13 | C13H9BrN2O4 | 100 MG
Thalidomide-5-Br is a brominated thalidomide derivative supplied for research use in studies of inflammation, tumor biology, and neurology. It is provided as a solid research reagent; consult lot-specific documentation for analytical details.
- Contains a bromodomain; used as a tool compound in biochemical and pharmacological research.
- Reported purity approximately 98% (see product documentation for lot-specific certificate of analysis).
- Solid, off-white to gray appearance suitable for analytical and synthetic applications.
- Storage recommendations: room temperature for shipping; in solution store at -80°C (2 years) or -20°C (1 year).
- Available in multiple pack sizes including 100 mg.
Medchemexpress LLC Thalidomide (Standard) | 50-35-1 | 100.0% | 258.23 | 50 MG
Thalidomide (Standard) | 50-35-1 | 100.0% | 258.23 | 50 MG