Lactams
Apexbio Technology LLC Sulbactam sodium,100mg CAS# 69388-84-7
Sulbactam sodium. Other sizes are also available. Please inqury us for quote.
Medchemexpress LLC Thalidomide-piperazine-PEG1-NH2 diTFA | 00-00-0 | 99.4% | C25H29F6N5O9 | 10MG
Thalidomide-Piperazine-PEG1-NH2 diTFA is a synthesized E3 ligase ligand-linker conjugate that combines a thalidomide-based cereblon ligand with a short PEG1/piperazine linker for PROTAC design. Intended for research use only, the compound is supplied as a solid (white to yellow) with characterized solubility and storage recommendations to support experimental workflows.
- High purity for research use (99.4%).
- Thalidomide-based cereblon ligand facilitates E3 ligase recruitment.
- Short PEG1/piperazine linker suitable for PROTAC assembly.
- DMSO solubility: 100 mg/mL; sonication recommended.
- In vivo formulation options reach ~2.5 mg/mL as suspended or clear solutions.
- Storage: sealed at 4°C; in solvent -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Thalidomide-4-O-C7-NH2 hydrochloride | 00-00-0 | 99.8% | C20H26ClN3O5 | 10MG
Thalidomide-4-O-C7-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand-linker conjugate provided as the hydrochloride salt for research use in PROTAC development and E3 ligase recruitment studies. It is supplied as a high-purity, well-characterized reagent suitable for biochemical assays, linker conjugation, and medicinal chemistry workflows.
- High purity (99.8%) suitable for research applications.
- Hydrochloride salt form for consistent handling and storage.
- Characterized molecular formula C20H26ClN3O5 and molecular weight 387.43 g/mol.
- Functions as a cereblon (CRBN) E3 ligase ligand for PROTAC design.
- Available in small, lab-scale quantities for screening and synthesis.
- Datasheet and certificate of analysis available from the supplier.
Medchemexpress LLC Thalidomide-C2-amido-C2-COOH | 2353496-84-9 | 98.5% | C19H20N4O7 | 10MG
Thalidomide-C2-amido-C2-COOH is a thalidomide-derived cereblon (CRBN) ligand-linker conjugate for research use. Supplied as a powder, it is intended as a building block for design and synthesis of PROTAC degraders and other molecules that recruit the CRBN E3 ubiquitin ligase.
- Incorporates a cereblon-binding thalidomide moiety for E3 ligase recruitment.
- Contains a short C2-amido-C2-COOH linker for conjugation to target ligands.
- High purity (98.5%) suitable for synthetic and analytical work.
- Molecular formula and weight provided to support design calculations.
- Soluble in DMSO for preparation of concentrated stock solutions.
- Powder form allows long-term frozen storage for stability.
Medchemexpress LLC Thalidomide-O-COOH | 1061605-21-7 | MFCD31560477 | 99.9% | 332.26 g/mol | C15H12N2O7 | 5 G
Thalidomide-O-COOH is a thalidomide-derived carboxylic acid used as a cereblon (CRBN) ligand building block in PROTAC design and E3 ligase recruitment studies. It is supplied as a high-purity research chemical in small laboratory pack sizes for medicinal chemistry and chemical biology applications.
- Thalidomide-derived cereblon ligand for PROTAC design.
- Carboxylic acid functionality enables linker attachment and derivatization.
- Supplied as a solid suitable for standard laboratory storage.
- Provided in small research pack sizes for synthesis and assay development.
- High reported purity supports use in chemical biology experiments.
Medchemexpress LLC Thalidomide-O-amido-PEG3-C2-NH2 TFA | 1957236-21-3 | 99.6% | 620.53 g/mol | C25H31F3N4O11 | 10 MG
Thalidomide-O-amido-PEG3-C2-NH2 TFA is a thalidomide-based cereblon ligand-linker conjugate (trifluoroacetic acid salt) designed as a building block for PROTAC synthesis. It links a thalidomide-derived E3 ligase ligand to a three-unit PEG spacer terminating in a C2 amino handle, enabling attachment to targeting ligands and facilitating cereblon-mediated target degradation.
- Thalidomide-based cereblon ligand for E3 ligase recruitment.
- Three-unit PEG linker providing flexible spacing and solubility.
- C2 amino terminal suitable for amide or urea coupling.
- Trifluoroacetic acid salt form for improved handling and stability.
- Molecular formula C25H31F3N4O11; molecular weight 620.53 g/mol.
- Soluble in DMSO at 50 mg/mL; ultrasonic may be required.
- Recommended storage: 4°C sealed; in solvent store at -80°C (6 months) or -20°C (1 month).
- Available in small research quantities suitable for synthesis, e.g., 10 mg.
Medchemexpress LLC Thalidomide-O-amido-C4-N3 | 2098488-36-7 | MFCD31560486 | 98.4% | 428.40 g/mol | C19H20N6O6 | 10 MG
Thalidomide-O-amido-C4-N3 is a thalidomide-derived cereblon ligand-linker conjugate used as a building block in proteolysis-targeting chimera (PROTAC) and E3 ligase ligand research. It is provided with analytical characterization and storage guidance for research applications.
- Used as a cereblon ligand-linker conjugate for PROTAC and E3 ligase research.
- Molecular formula C19H20N6O6; molecular weight 428.40 g/mol.
- CAS number 2098488-36-7 for unambiguous identification.
- Purity 98.4% by LCMS (as supplied).
- Supplied in small research quantities (for example, 10 mg) and as stock solution preparations.
- Soluble in DMSO and compatible solvent systems for formulation.
- Store at 4°C under nitrogen; in solution, store at -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Thalidomide-o-amido-c4-n3 | 2098488-36-7 | 98.4% | 428.40 | C19H20N6O6 | 25 MG
Thalidomide-O-amido-C4-N3 is a thalidomide-derived cereblon ligand-linker conjugate containing an azide functional group. It is used as a building block in PROTAC design and as a click-chemistry reagent to attach CRBN ligands to alkyne-bearing partners, enabling targeted protein degradation applications.
- Azide functional group compatible with CuAAC and SPAAC click chemistry.
- Designed as a cereblon (CRBN) ligand-linker conjugate for PROTAC synthesis.
- High purity as supplied (LCMS ~98.4%).
- Soluble in DMSO (≥ 41 mg/mL) for in vitro formulation.
- In vivo formulation examples achieve ≥ 2.5 mg/mL in common solvents and vehicles.
- Store under inert atmosphere at 4°C; in solution store at -80°C for long-term stability.