Lactims
Medchemexpress LLC 7030B-C5 | 370871-42-4 | 99.8% | 359.38 | 5 MG
7030B-C5 is a potent PCSK9 inhibitor (IC50=1.61 μM) that significantly reduces plasma cholesterol and triglyceride (TG) levels in vivo. It slows the progression of atherosclerosis and is suitable for use in the study of cardiovascular diseases.
- Reduces plasma cholesterol
- Reduces triglyceride levels
- Slows atherosclerosis progression
- Useful in cardiovascular disease studies
Sigma Aldrich Fine Chemicals Biosciences Complement C5 from human s1MG
Complement C5 from human s1MG
Medchemexpress LLC (S,R,S)-AHPC-C5-NH2 dihydrochloride | 2415256-20-9 | 97.8% | 616.64 | 25 MG
(S,R,S)-AHPC-C5-NH2 dihydrochloride is a chemical compound with a molecular weight of 616.64. It appears as an off-white to light yellow solid and is suitable for research applications. This product is for research use only and has not been fully validated for medical applications.
- Chemical name: (2S,4R)-1-((S)-2-(6-Aminohexanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
- CAS number: 2415256-20-9
- Molecular formula: C28H43Cl2N5O4S
- Molecular weight: 616.64
- Purity: 97.8% (HPLC)
- Appearance: Off-white to light yellow solid
- Storage: -20°C, sealed storage, away from moisture. In solvent: -80°C for 6 months; -20°C for 1 month, sealed storage, away from moisture.
Medchemexpress LLC 6-(3,4-dibromo-2,5-dioxopyrrol-1-yl)hexanoic acid | 1443214-97-8 | MFCD09813286 | 99.4% | 369.01 g/mol | C10H11Br2NO4 | 50 MG
Dibromomaleimide-C5-COOH is a bifunctional dibromomaleimide linker used in antibody-drug conjugate synthesis to connect payloads such as MMAF. It is supplied as a white to off-white solid with high purity and is soluble in DMSO.
- Bifunctional dibromomaleimide linker for ADC synthesis.
- High purity (99.4%) suitable for research applications.
- Molecular weight 369.01 g/mol and formula C10H11Br2NO4.
- Soluble in DMSO at ≥100 mg/mL.
- Available in small-scale quantities (5-200 mg) for conjugation workflows.
- Store at 4°C under nitrogen; in solvent store at -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC AP-C5 | 2234272-10-5 | 98.1% | 100 MG
AP-C5 selectively inhibits guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 7.2, making it suitable for diarrheal disease research. It is also a click chemistry reagent containing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
- Inhibits cGMP-dependent cGKII-mediated protein phosphorylation.
- Effectively inhibits cGMP-dependent, CFTR-mediated anion secretion in intestinal tissue.
- Potentiates cAMP signaling through PDE inhibition.
- Partially blocks heat-stable toxin (STa)-mediated short-circuit current (Isc) response in mouse ileum.
Gold Biotechnology Inc Cycloheximide 5 g
Cycloheximide is a protein synthesis inhibitor in eukaryotic cells. It prevents ribosomal mRNA translocation during protein translation. Cycloheximide has a variety of applications. It can be used to study cellular processes and to determine the half-life of a protein using western blotting techniques of protein cell lysate. It has been used to select for CHX-resistant strains of yeast and fungi. It also displays neuroprotective properties. Additionally, Cycloheximide has been used to inhibit yeast growth at concentrations of 200μM. It has been used to promote production of ethylene in leaves and fruit.
Medchemexpress LLC DNA2 inhibitor C5 | 35973-25-2 | 98.1% | 25 MG
DNA2 inhibitor C5 is a potent, competitive, and specific DNA2 nuclease inhibitor with an IC50 of 20 μM. It inhibits the nuclease, DNA-dependent ATPase, helicase, and DNA-binding activities of DNA2. This product can be used in breast cancer and colorectal cancer research.
- Potent, competitive, and specific DNA2 nuclease inhibitor
- IC50 of 20 μM
- Inhibits nuclease, DNA-dependent ATPase, helicase, and DNA-binding activities of DNA2
- Can be used in breast cancer and colorectal cancer research
Medchemexpress LLC Glutarimide-isoindolinone-NH-PEG2-COOH | 2803827-03-2 | 98.5% | 419.43 | 100 MG
Glutarimide-Isoindolinone-NH-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates a cereblon ligand
- Utilizes a linker in PROTAC technology
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Targets Cereblon
- For research use only
Medchemexpress LLC Dbm-C5-VC-PAB-MMAE | 1644228-55-6 | 99.5% | 1474.42 | C68H103Br2N11O15 | 10 MG
DBM-C5-VC-PAB-MMAE is a drug-linker conjugate used to construct antibody-drug conjugates (ADCs); it combines a C5-VC-PAB cleavable linker with a maleimide DBM attachment and the cytotoxic payload MMAE.
- Drug-linker conjugate for ADC construction.
- Purity 99.5%.
- Molecular weight 1474.42.
- Chemical formula C68H103Br2N11O15.
- CAS number 1644228-55-6.
- Supplied as 10 MG per package.
![Medchemexpress LLC Borate, 5-[(3,5-dimethyl-2H-pyrrol-2-ylidene)methyl]-1H-pyrrole-2-pentanoato difluoro | 217075-24-6 | 99.7% | 320.14 g/mol | C16H19BF2N2O2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000298852.png-250.jpg)
Medchemexpress LLC Borate, 5-[(3,5-dimethyl-2H-pyrrol-2-ylidene)methyl]-1H-pyrrole-2-pentanoato difluoro | 217075-24-6 | 99.7% | 320.14 g/mol | C16H19BF2N2O2 | 10 MG
BODIPY FL C5 is a green fluorescent fatty acid probe used for labeling lipids and membranes and as a precursor for synthesizing fluorescent phospholipids. It fluoresces in both aqueous and lipid environments and is supplied as an orange to red solid at high purity for research applications. Not for drug or household use.
- High purity (99.7%).
- Fluoresces in aqueous and lipid environments.
- Suitable for membrane labeling and lipid trafficking assays.
- Orange to red solid, easy to handle.
- Supplied in 10 mg quantities for laboratory workflows.
- Includes COA and SDS for quality and safety information.
Gold Biotechnology Inc Cycloheximide 25 g
Cycloheximide is a protein synthesis inhibitor in eukaryotic cells It prevents ribosomal mRNA translocation during protein translation Cycloheximide has a variety of applications It can be used to study cellular processes and to determine the half-life of a protein using western blotting techniques of protein cell lysate It has been used to select for CHX-resistant strains of yeast and fungi It also displays neuroprotective properties Additionally Cycloheximide has been used to inhibit yeast growth at concentrations of 200 M It has been used to promote production of ethylene in leaves and fruit
Medchemexpress LLC Bodipy FL C5-ceramide | 133867-53-5 | 98.9% | 601.62 | C34H54BF2N3O3 | 10 MG
BODIPY FL C5-Ceramide is a BODIPY-labeled ceramide derivative used as a Golgi-specific green fluorescent dye for fluorescence microscopy. It is synthesized in the endoplasmic reticulum and trafficked to the Golgi apparatus, enabling selective labeling of Golgi membranes in live and fixed cells.
- Golgi-specific fluorescent labeling for microscopy.
- Bright green fluorescence with excitation/emission at 505/511 nm.
- High purity suitable for imaging applications.
- Solid, brown-to-red appearance; stable when stored protected from light at -20 °C.
- Supplied in small-mass quantities suitable for laboratory imaging workflows.
Medchemexpress LLC 2-Pyrimidinamine, 4-[4-(1H-imidazol-1-yl)phenyl]-N-2-propyn-1-yl- | 2234272-10-5 | 98.1% | 25 MG
AP-C5 is a selective inhibitor of cGMP-dependent protein kinase II (cGKII) with a pIC50 of 7.2. It can be used for research on diarrheal disease and also functions as a click chemistry reagent containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
- Selective inhibitor of cGMP-dependent protein kinase II (cGKII)
- pIC50 of 7.2 for cGKII
- Useful for diarrheal disease research
- Click chemistry reagent with an alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Potentiates cAMP signaling by PDE inhibition
- Partially blocks heat-stable toxin (STa)-mediated short-circuit current (Isc) response in mouse ileum
Gold Biotechnology Inc Cycloheximide 1 g
Cycloheximide is a protein synthesis inhibitor in eukaryotic cells It prevents ribosomal mRNA translocation during protein translation Cycloheximide has a variety of applications It can be used to study cellular processes and to determine the half-life of a protein using western blotting techniques of protein cell lysate It has been used to select for CHX-resistant strains of yeast and fungi It also displays neuroprotective properties Additionally Cycloheximide has been used to inhibit yeast growth at concentrations of 200 M It has been used to promote production of ethylene in leaves and fruit
TARGETMOL CHEMICALS INC COMPLEMENT C5-IN-1 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5). purity: 99%