Lactones
![Medchemexpress LLC 2H-1-Benzazepin-2-one, 6-fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)- | 1093978-89-2 | >98.8% | C25H22F4N6O2 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC 2H-1-Benzazepin-2-one, 6-fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)- | 1093978-89-2 | >98.8% | C25H22F4N6O2 | 50 MG
This is a potent and selective modulator for the study of Alzheimer's disease. It has been shown to inhibit gamma-secretase activity in various cell lines, leading to a decrease in amyloid beta levels.
- Potent and selective modulation of gamma-secretase.
- Suitable for research into Alzheimer's disease.
- Demonstrates cellular effects in HEK293, HeLa, and SH-SY5Y cell lines.
- High purity of 98.80%.
- Available in various quantities, including free samples.
- Detailed documentation including data sheet, SDS, and handling instructions.
- Soluble in DMSO for in vitro applications.
- In vivo dissolution protocols provided.
Sigma Aldrich Fine Chemicals Biosciences gamma-Hexalactone 98 fCC f1KG
GAMMA602 gamma-Hexalactone 98 fCC f1KG
![eMolecules 1256240-40-0 | rel-(3aR,5r,6aS)-octahydrocyclopenta[c]pyrrol-5-ol;hydrochloride | MFCD22376584 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502157451.JPG-250.jpg)
eMolecules 1256240-40-0 | rel-(3aR,5r,6aS)-octahydrocyclopenta[c]pyrrol-5-ol;hydrochloride | MFCD22376584 | 1g
Ambeed | 13-Dibromo-57-bis(2-ethylhexyl)-4H8H-benzo[12-c45-c]dithiophene-48-dione | 1g | 672522751 | A1156392 | 1415929-76-8 | 602.480 | C26H34Br2O2S2
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eMolecules Building Block Tool
Medchemexpress LLC AMPK gamma 1 Antibody (YA621) | 38 kDa | 100 UL
This AMPK gamma 1 Antibody (YA621) is a rabbit-derived, non-conjugated IgG monoclonal antibody, targeting to AMPK gamma 1. It is formulated in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol and 0.05% BSA, with 0.01% Sodium azide as a preservative. This antibody is suitable for Western Blot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), and Immunoprecipitation (IP) applications, and has a concentration of 0.5 mg/mL. The predicted and observed molecular weight is 38 kDa. It is reactive with human samples.
- Rabbit-derived and non-conjugated IgG monoclonal antibody
- Targets AMPK gamma 1
- Suitable for Western Blot, ICC/IF, and Immunoprecipitation
- Concentration of 0.5 mg/mL
- Predicted and observed molecular weight: 38 kDa
- Reactivity: Human
- Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Medchemexpress LLC Fc gamma RIIB/CD32b 50ug | 50ug
Fc RIIB/CD32b proteins exhibit low affinity as complexes or receptors that aggregate the immunoglobulin Fc region ITIM phosphorylated by Fc RIIB/CD32b recruits inositol phosphatases SHIP1 and SHIP2 inhibits Ras activation down-regulates MAPK activity reduces PLC- function and results in PKC activation Inhibition of MAP kinase pathway and anti-apoptotic kinase Akt inhibit cell proliferation and survival Fc gamma RIIB/CD32b Protein Cynomolgus (HEK293 His) is the recombinant cynomolgus-derived Fc gamma RIIB/CD32b protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC Fc gamma RIIIA/CD16a protein, rat | 5 UG
Recombinant rat Fc gamma RIIIA (CD16a) extracellular domain expressed in HEK293 cells with a C-terminal His tag. Supplied as a small, purified protein for receptor binding studies, antibody-dependent cellular cytotoxicity (ADCC) assays, and in vitro functional characterization.
- Rat extracellular domain expressed in HEK293 cells.
- C-terminal His tag for convenient detection and purification.
- Glycosylated to retain native binding properties.
- Suitable for binding assays and receptor characterization.
- Shipped frozen with recommended storage for long-term stability.
Medchemexpress LLC Fc gamma RIII/CD16 50ug | 50ug
The Fc gamma RIII/CD16 protein is a receptor for IgG and is optimally activated upon binding to aggregated antigen-IgG complexes initiating antibody-dependent cellular cytotoxicity (ADCC) and preventing inappropriate effector cell activation It mediates IgG effector functions on NK cells generating memory-like adaptive NK cells to efficiently eliminate virally infected cells Fc gamma RIII/CD16 Protein Rhesus Macaque (HEK293 His) is the recombinant Rhesus Macaque-derived Fc gamma RIII/CD16 protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC AMPK gamma 1/beta 2/alpha 1 heterotrimer protein, human | 96.3% | 10 UG
Recombinant human AMPK α1β2γ1 heterotrimer protein expressed in Sf9 insect cells with an N-terminal His-GST tag. Supplied as a purified recombinant complex for in vitro kinase assays, biochemical characterization, and screening of modulators that affect AMPK activity.
- Expressed in Sf9 insect cells with an N-terminal His-GST tag.
- Purity approximately 96.3%.
- Subunit molecular weights approx. 95 kDa (α1), 37 kDa (β2), 35 kDa (γ1).
- Validated for in vitro kinase assays and biochemical profiling.
- Supplied in microgram quantities suitable for biochemical assays.
Medchemexpress LLC IFN-gamma Porcine 5ug | 5ug
IFN-gamma (interferon-gamma) is a type II interferon produced by immune cells such as T cells and NK cells It plays a key role in antibacterial antiviral and anti-tumor responses by activating effector immune cells and enhancing antigen presentation effect Its main signaling pathway involves the JAK-STAT pathway that interacts with its receptor IFNGR1 affecting gene regulation IFN-gamma Protein Pig is the recombinant Pig-derived IFN-gamma protein expressed by E coli with tag free
Medchemexpress LLC Gamma-glutamyl-arginine | 31106-03-3 | 97.7% | 303.31 | C11H21N5O5 | 10 MG
Gamma-glutamyl-arginine (L-γ-glutamyl-L-arginine) is a γ-glutamic acid-derived dipeptide isolated from Panax ginseng. Supplied as a purified research chemical (purity ~97.7%), it is intended for biochemical and natural product research and is provided with supporting documentation such as a certificate of analysis and a safety data sheet.
- Dipeptide structure: composed of γ-glutamic acid and arginine.
- High purity suitable for analytical and biochemical applications.
- Supplied in small quantities appropriate for research workflows.
- Documentation provided: COA and SDS for handling and quality verification.
- Molecular weight approximately 303.31 g/mol.
Medchemexpress LLC Bd-1008 dihydrobromide | 138356-09-9 | 98.1% | 463.08 g/mol | C15H24Br2Cl2N2 | 25 MG
BD-1008 dihydrobromide is a research-grade sigma (σ) receptor antagonist used in neuropharmacology and addiction-related studies. It is commonly applied in receptor binding assays, dopamine microdialysis, and preclinical pharmacology to probe σ receptor function and dopaminergic signaling.
- High affinity for σ1 and σ2 receptors (Ki ≈ 2 nM and 8 nM).
- Low affinity for D2 receptor and dopamine transporter, reducing off-target effects.
- High purity (98.07%), suitable for research applications.
- Available in small research pack sizes, including 25 MG.
- Solid form with molecular weight of approximately 463.08 g/mol.
Medchemexpress LLC CEBP gamma/CEBPG Hu 5ug
CEBP gamma/CEBPG protein is a transcription factor that regulates genes by binding to their promoter and enhancer regions It targets IL-4 and immunoglobulin heavy chains binding to enhancer elements PRE-I and GPE1 in the G-CSF gene promoter CEBP gamma/CEBPG Protein Human (His) is the recombinant human-derived CEBP gamma/CEBPG protein expressed by E coli with N-His labeled tag
Medchemexpress LLC Fc gamma RIII/CD16 10ug | 10ug
The Fc RIIIA/CD16a protein is a receptor for IgG and is optimally activated upon binding of aggregated antigen-IgG complexes inducing antibody-dependent cellular cytotoxicity (ADCC) It mediates IgG effector function on natural killer cells limiting viral load Fc gamma RIII/CD16 Protein Cynomolgus (HEK293 His) is the recombinant cynomolgus-derived Fc gamma RIII/CD16 protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC NH2 DOTA-GA | 1639843-65-4 | 518.56 | C21H38N6O9 | 50 MG
NH2 DOTA-GA is a DOTA-based bifunctional metal chelator used to prepare radionuclide drug conjugates (RDCs), with carboxylic acid groups capable of complexing metal ions such as Gd(III).
- Bifunctional DOTA chelator for radiolabeling of biomolecules.
- Suitable for preparation of radionuclide-drug conjugates.
- Molecular formula C21H38N6O9; molecular weight 518.56.
- Available as a 50 mg powder; stable for 3 years at -20°C when stored as recommended.
- Listed CAS number 1639843-65-4 for unambiguous identification.