Oxazinanes
Cayman Chemical PIK75 hydrochloride
A selective inhibitor of p110α with an IC50 value of 5.8 nM; inhibits p110γ and p110β with IC50 values of 0.076 µM and 1.3 µM, respectively
Cayman Chemical DLthreoPDMP hydrochloride
An inhibitor of sphingolipid biosynthesis; inhibits glucosylceramide synthase by 33 and 48% in MDCK cell homogenates at 5 and 10 µM; reduces the synthesis of glucosylceramide increases cellular ceramide, and induces cell cycle arrest; increases Aβ42 and Aβ39 production independent of ceramide metabolism via modulation of γ-secretase activity
Medchemexpress LLC BP 897 hydrochloride 10mM 1mL | 314776-92-6 | 10MM 1ML
BP 897 hydrochloride is a potent and partial dopamine D3 receptor agonist and a weak D2 receptor antagonist BP 897 hydrochloride displays a high affinity at the dopamine D3 receptor (Ki 0 92 nM) and a 70 times lower affinity at the D2 receptor (Ki 61 nM)[1
Selleck Chemical LLC Filanesib hydrochloride
Filanesib (ARRY-520) hydrochloride is a kinesin spindle protein (KSP) inhibitor that blocks the separation of centrosomes and assembly of spindles in the early stage of cell mitosis and cell proliferation
Cayman Chemical EthylLNIO hydrochloride
A modestly selective NOS inhibitor with Ki values for inhibition of nNOS, eNOS, and iNOS of 5.3, 18, and 12 µM, respectively; however, does not show biologically significant selectivity for nNOS over eNOS, and instead favors iNOS (Ki/Km = 3.79, 5, and 0.96 µM, respectively)
Apexbio Technology LLC Yohimbine Hydrochloride 65-19-0 10mM (in 1mL DMSO)
Yohimbine Hydrochloride (65-19-0) is a small-molecule antagonist targeting -2 adrenergic receptors It is designed to selectively bind to pre- and postsynaptic -2 adrenergic receptors thereby reducing receptor-mediated inhibition and increasing the synaptic release of norepinephrine and dopamine Yohimbine Hydrochloride exerts its biological activity primarily through antagonism of -2 adrenergic receptors Reported IC50 values for inhibition at -2 adrenergic receptor subtypes generally range between 40 90 nM depending on receptor subtype and assay conditions Based on these pharmacological properties Yohimbine Hydrochloride holds research potential in neuroscience particularly in studies investigating the neurobiological mechanisms underlying anxiety depression and addiction-related behaviors
Medchemexpress LLC W-7 hydrochloride | 61714-27-0 | MFCD00012559 | 100.0% | 377.33 g/mol | C16H22Cl2N2O2S | 1 ML
W-7 hydrochloride is a selective calmodulin antagonist used in biochemical and pharmacological research. It inhibits Ca2+-calmodulin-dependent phosphodiesterase and myosin light chain kinase, can induce apoptosis, and is used in studies of Kv4.3 channel function and arrhythmia mechanisms.
- Selective calmodulin antagonist suitable for biochemical assays.
- Inhibits Ca2+-calmodulin-dependent enzymes and myosin light chain kinase.
- Acts as a Kv4.3 channel blocker for electrophysiology research.
- Available as 10 mM solution in DMSO (1 mL) or as solid in multiple milligram sizes.
- High purity (≈99.96%) for reproducible results.
- Identified by CAS 61714-27-0 and standard chemical identifiers for unambiguous reference.
Selleck Chemical LLC Triprolidine Hydrochloride S5447-25mg
Triprolidine Hydrochloride is the hydrochloride salt form of Triprolidine which is the first generation histamine H1 antagonist used in allergic rhinitis
TARGETMOL CHEMICALS INC Tiaspirone hydrochloride 1MG
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. Tiaspirone hydrochloride (BMY-13859 hydrochloride) exhibits antipsychotic activity. Tiaspirone hydrochloride influences the electrophysiological activity of dopaminergic neurons in the substantia nigra zona compacta (A9 DA cells) and ventral tegmental area (A10 DA cells) in the brain of the rat. Purity 99.98%
eMolecules 4-(Pyrrolidin-3-yl)morpholine dihydrochloride | 1219979-89-1 | MFCD13561583 | 1g
Combi-Blocks, Inc. | 4-(Pyrrolidin-3-yl)morpholine dihydrochloride | 1g | 569297340 | OT-5509 | 95.000 | 1219979-89-1 | MFCD13561583 | 229.150 | C8H18Cl2N2O
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC tert-Butyl((1S,5R,6S)-3-azabicyclo[3.3.0]octan-6-yl)carbamate | 1228030-08-7 | 95.0% | C12H22N2O2 | 1 MG
This chemical is tert-Butyl((1S,5R,6S)-3-azabicyclo[3.3.0]octan-6-yl)carbamate, identified for use as a laboratory chemical and in the manufacture of substances. It is a solid compound with a molecular weight of 226.32.
- Stable under recommended storage conditions
- Requires handling precautions to avoid inhalation and contact with eyes and skin
- Should be stored in a cool, well-ventilated area, away from direct sunlight and ignition sources
- Powder stable for 3 years at -20°C or 2 years at 4°C
- In solvent, stable for 6 months at -80°C or 1 month at -20°C
- Shipping at room temperature if less than 2 weeks