Oxazinanes
Selleck Chemical LLC KHS101 hydrochloride
KHS101 is a small-molecule inhibitor of TACC3 which is a key component of centrosome-microtubule dynamic networks
eMolecules 16681-67-7 | 4-Bromo-2-methyl-2H-1,2,3-triazole | Ambeed | MFCD23378485 | 161.990 | C3H4BrN3 | 95.000 | Cn1ncc(Br)n1 | 1g | 525043184
4-Bromo-2-methyl-2H-1,2,3-triazole | Ambeed | 16681-67-7 | MFCD23378485 | 161.990 | C3H4BrN3 | 95.000 | Cn1ncc(Br)n1 | 1g | 525043184
Cayman Chemical PIK75 hydrochloride
A selective inhibitor of p110α with an IC50 value of 5.8 nM; inhibits p110γ and p110β with IC50 values of 0.076 µM and 1.3 µM, respectively
Selleck Chemical LLC GPNA hydrochloride
GPNA hydrochloride (L- -glutamyl-p-nitroanilide hydrochloride) is a substrate of -glutamyltransferase (GGT) and an inhibitor of the glutamine transporter ASCT2 with an IC50 of 250 M in A549 cells It also inhibits Na -dependent carriers SNAT1 -2 -4 -5 and Na -independent leucine transporters LAT1/2 It can be widely used in research on pancreatic cancer breast cancer glioblastoma multiforme acute myelogenous leukemia and non-small-cell lung cancer
Aobchem 5-Bromo-2-(phenylmethyl)-2H-indazole | ≥97% | CAS 937049-51-9 | C14H11BrN2 | 500mg
5-Bromo-2-(phenylmethyl)-2H-indazole | ≥97% | CAS 937049-51-9 | C14H11BrN2 | 500mg
Aobchem 4-Bromo-3 6-dihydro-2H-thiopyran 1 1-dioxide | ≥97% | CAS 1195706-31-0 | C5H7BrO2S | 500mg
4-Bromo-3 6-dihydro-2H-thiopyran 1 1-dioxide | ≥97% | CAS 1195706-31-0 | C5H7BrO2S | 500mg
Aobchem 4-Bromo-2 3-dihydro-1H-indene | ≥97% | CAS 6134-53-8 | C9H9Br | 500mg
4-Bromo-2 3-dihydro-1H-indene | ≥97% | CAS 6134-53-8 | C9H9Br | 500mg
Aobchem 6-Bromo-5-fluoro-2-methyl-2H-indazole | ≥95% | CAS 1286734-87-9 | C8H6BrFN2 | 5g
6-Bromo-5-fluoro-2-methyl-2H-indazole | ≥95% | CAS 1286734-87-9 | C8H6BrFN2 | 5g
Aobchem 6-Chloro-1 3-dihydro-2 1-benzoxaborol-1-ol | ≥97% | CAS 174671-43-3 | C7H6BClO2 | 250mg
6-Chloro-1 3-dihydro-2 1-benzoxaborol-1-ol | ≥97% | CAS 174671-43-3 | C7H6BClO2 | 250mg
Medchemexpress LLC Bomedemstat dihydrochloride | 99.6% | 592.54 | 50 MG
Bomedemstat dihydrochloride is an orally active and irreversible lysine-specific demethylase 1 (LSD1) inhibitor. It increases H3K4 and H3K9 methylation to alter gene expression, showing anti-cancer activities by inhibiting cancer cell proliferation and inducing apoptosis.
- Orally active.
- Irreversible LSD1 inhibitor.
- Increases H3K4 and H3K9 methylation.
- Alters gene expression.
- Exhibits anti-cancer activities.
- Inhibits cancer cell proliferation.
- Induces apoptosis.
- Selectively inhibits proliferation and induces apoptosis of Jak2V617F cells.
- Enhances cell survival and induces apoptosis via BCL-XL and PUMA.
- Leads to cell cycle arrest.
- Normalizes or improves blood cell counts in animal models.
- Reduces spleen volumes in animal models.
- Restores normal splenic architecture.
- Reduces bone marrow fibrosis in animal models.
eMolecules 1149-23-1 | Diethyl 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate | Apollo Scientific US - Building Blocks | MFCD00005951 | 253.298 | C13H19NO4 | 95.000 | CCOC(=O)C1=C(C)NC(C)=C(C1)C(=O)OCC | 100g | 398005521
Diethyl 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate | Apollo Scientific US - Building Blocks | 1149-23-1 | MFCD00005951 | 253.298 | C13H19NO4 | 95.000 | CCOC(=O)C1=C(C)NC(C)=C(C1)C(=O)OCC | 100g | 398005521