Piperidines
Medchemexpress LLC PI 3 Kinase p150 Antibody (YA2823) | 100 UL
The PI 3 Kinase p150 Antibody (YA2823) is a rabbit-derived antibody supplied as a liquid. It is intended for laboratory use in the manufacture of substances and is reactive with human, mouse, and rat samples. This antibody is stable under recommended storage conditions and has an observed molecular weight of 150 kDa.
- Reacts with human, mouse, and rat samples.
- Supports Western Blot (WB), Immunohistochemistry (IHC-P), Immunocytochemistry/Immunofluorescence (ICC/IF), and Flow Cytometry (FC) applications.
- Formulated in rabbit IgG in 10mM phosphate buffered saline, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
- Stable for 1 year when stored at -20°C; avoid repeated freeze/thaw cycles.
- Shipped with blue ice to maintain stability.
Apexbio Technology LLC PI-1840 1401223-22-0 50mg
PI-1840 (CAS 1401223-22-0) is a potent selective and rapidly reversible noncovalent inhibitor of the proteasome chymotrypsin-like (CT-L) activity It exhibits an IC50 of 27 nM against CT-L catalytic function of the proteasome with significantly greater selectivity over other proteolytic activities including PGPH-L and T-L In MDA-MB-468 human breast cancer cells PI-1840 inhibits CT-L activity (IC50 0 37 M) suppresses cell viability and proliferation and induces accumulation of CT-L substrates such as I B- p27 and Bax ultimately triggering apoptosis via PARP cleavage and caspase-3 activation In vivo PI-1840 markedly reduces tumor growth in a breast cancer xenograft model This compound is valuable for investigating proteasome function apoptosis and cancer biology
Medchemexpress LLC YKL-05-099 (5MG)
YKL-05-099 is a salt-inducible kinase (SIK) probe; inhibits SIK2 with an IC50 of 40 nM.Purity: 99.76%, CAS 1936529-65-5
Matrix Scientific 4-PHENYLPIPERIDINE MF C11H15N MW 161.25 CAS 771-99-3 MDL MFCD00006002 QTY 5 UOM G
4-PHENYLPIPERIDINE MF C11H15N MW 161.25 CAS 771-99-3 MDL MFCD00006002 QTY 5 UOM G
eMolecules Ambeed / N-(4-Bromophenyl)pyrrolidine / 250mg / 524996554 / A107631 / / 22090-26-2 / MFCD04112480 / 226.117 / C10H12BrN
Ambeed / N-(4-Bromophenyl)pyrrolidine / 250mg / 524996554 / A107631 / / 22090-26-2 / MFCD04112480 / 226.117 / C10H12BrN
Medchemexpress LLC HY-12059A 5mg Medchemexpress, AT7867 (dihydrochloride) CAS:1431697-86-7 Purity:>98%
Medchemexpress, HY-12059A 5mg AT7867 (dihydrochloride) CAS:1431697-86-7 AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1/Akt2/Akt3 and p70S6K/PKA with IC50s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules Medchem Express / AMG-548 (dihydrochloride) / 1mg / 495799682 / HY-108642B / / 2518299-32-4 / MFCD26793881 / 534.490 / C29H29Cl2N5O
Medchem Express / AMG-548 (dihydrochloride) / 1mg / 495799682 / HY-108642B / / 2518299-32-4 / MFCD26793881 / 534.490 / C29H29Cl2N5O
Medchemexpress LLC HY-50844 500mg , Ibutamoren (Mesylate) MK-677;MK-0677 CAS:159752-10-0 Purity:98%
Medchemexpress, HY-50844 500mg Ibutamoren (Mesylate) MK-677;MK-0677 CAS:159752-10-0 Formula:C28H40N4O8S2 Purity:98% Ibutamoren (Mesylate) is a potent, non-peptide Growth hormone secretagogue receptor (GHSR) agonist. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC 2-(2-phenylethylsulfanyl)pyridine-3-carboxylic acid | 496775-95-2 | MFCD03621206 | 99.8% | 259.32 g·mol⁻1 | C14H13NO2S | 25MG
ML-099 (CID-888706) is a small-molecule pan Ras-related GTPases activator used in biochemical and cell-based research to activate Rac1, Cdc42, Ras, Rab7, and Rab-2A. It is supplied for research use only and is provided in high-purity solid form or as a DMSO solution suitable for in vitro assays.
- Activates multiple small GTPases including Rac1, Cdc42, Ras, Rab7, and Rab-2A.
- High purity suitable for biochemical and cell-based assays (99.8%).
- Available as solid in small milligram quantities and as a 10 mM solution in DMSO.
- Molecular formula C14H13NO2S and molecular weight 259.32 g·mol⁻1.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC RIDR-PI-103 | 2581114-71-6 | 98.0% | C27H25N7O4 | 25 MG
RIDR-PI-103 is a reactive oxygen species (ROS)-induced agent release proagent. It features a self-cyclizing moiety linked to a pan-PI3K inhibitor (PI-103). It has been observed that Doxorubicin and RIDR-PI-103 exhibit a synergistic effect in MDA-MB-361 and MDA-MB-231 cells, leading to the inhibition of cancer cell proliferation. This product is intended for research use only.
- Reactive oxygen species (ROS)-induced agent release proagent
- Features a self-cyclizing moiety linked to a pan-PI3K inhibitor (PI-103)
- Exhibits synergistic effect with Doxorubicin in MDA-MB-361 and MDA-MB-231 cells to inhibit cancer cell proliferation
- Targets reactive oxygen species
- Targets immunology/inflammation pathway
- Targets metabolic enzyme/protease pathway
- Targets NF-κB pathway
Medchemexpress LLC HY-114428 5mg Medchemexpress, P110δ-IN-1 CAS:1595129-71-7 Purity:>98%
Medchemexpress, HY-114428 5mg P110δ-IN-1 CAS:1595129-71-7 P110δ-IN-1 is a potent and selective inhibitor of P110δ extracted from patent WO 2014055647 A1, with an IC 50 of 8.4 nM [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 4-Piperidinoaniline, HCl | 110475-33-7 | MFCD02631949 | 1g
Combi-Blocks | 4-Piperidinoaniline, HCl | 1g | 232336667 | ST-5988 | 98.000 | 110475-33-7 | MFCD02631949 | 212.720 | C11H17ClN2
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Medchemexpress LLC Varenicline hydrochloride | 230615-23-3 | 99.9% | 247.72 g/mol | C13H14ClN3 | 5 MG
Varenicline hydrochloride is the hydrochloride salt of varenicline, an orally active partial agonist of the α4β2 nicotinic acetylcholine receptor. This compound is supplied as a research-grade chemical for in vitro and in vivo studies investigating nicotinic receptor pharmacology and models of nicotine dependence.
- High purity suitable for analytical and preclinical studies.
- Supplied as a hydrochloride salt for increased stability and solubility.
- Molecular formula C13H14ClN3 and molecular weight 247.72 g/mol.
- Identified by CAS number 230615-23-3 for unambiguous chemical reference.
- Compatible with common solvents such as DMSO for solution preparation.
- Intended for laboratory research use only.
Medchemexpress LLC BI-9627 hydrochloride | 1422252-46-7 | 98.0% | 392.80 g/mol | C16H20ClF3N4O2 | 10 MG
BI-9627 hydrochloride is the hydrochloride salt of a potent sodium-hydrogen exchanger 1 (NHE1) inhibitor supplied for research use. The compound is intended for biochemical and pharmacological studies of NHE1 activity and is accompanied by analytical documentation to support quality and identity.
- Potent NHE1 inhibition at low nanomolar concentrations.
- Hydrochloride salt form improves solubility for formulation and handling.
- High purity suitable for research applications and analytical studies.
- Characterized molecular weight 392.80 g/mol and formula C16H20ClF3N4O2.
- Supplied with supporting documentation such as COA and analytical data.
Medchemexpress LLC HY-101755 5mg Medchemexpress, Tedatioxetine (hydrobromide) CAS:960151-65-9 Purity:>98%
Medchemexpress, HY-101755 5mg Tedatioxetine (hydrobromide) CAS:960151-65-9 Tedatioxetine (Lu AA24530) hydrobromide acts as a serotonin and norepinephrine (NE)-preferring triple reuptake inhibitor (TRI) and 5-HT2A, 5-HT2C, 5-HT3 and α1A-adrenergic receptor antagonist
., Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.