Piperidines
Medchemexpress LLC HY-101027A 100mg Medchemexpress, GSK4028 CAS:2079886-19-2 Purity:>98%
Medchemexpress, HY-101027A 100mg GSK4028 CAS:2079886-19-2 GSK4028 is the enantiomeric negative control of GSK4027, which is a PCAF/GCN5 bromodomain chemical probe, the pIC 50 of GSK4028 is 4.9 in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC YKL-05-099 (5MG)
YKL-05-099 is a salt-inducible kinase (SIK) probe; inhibits SIK2 with an IC50 of 40 nM.Purity: 99.76%, CAS 1936529-65-5
eMolecules 61676-62-8 | 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | AA Blocks LLC | MFCD00192241 | 186.060 | C9H19BO3 | 0.000 | CC(C)OB1OC(C)(C)C(C)(C)O1 | 25g | 489787647
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | AA Blocks LLC | 61676-62-8 | MFCD00192241 | 186.060 | C9H19BO3 | 0.000 | CC(C)OB1OC(C)(C)C(C)(C)O1 | 25g | 489787647
![eMolecules 375815-87-5 | Varenicline Tartrate | J & W PharmLab LLC361.354 | C17H19N3O6 | 96.000 | OC(C(O)C(O)=O)C(O)=O.C1[C@H]2CNC[C@@H]1c1cc3nccnc3cc21 | 5mg | 553410033](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502451486.PNG-250.jpg)
eMolecules 375815-87-5 | Varenicline Tartrate | J & W PharmLab LLC361.354 | C17H19N3O6 | 96.000 | OC(C(O)C(O)=O)C(O)=O.C1[C@H]2CNC[C@@H]1c1cc3nccnc3cc21 | 5mg | 553410033
Varenicline Tartrate | J & W PharmLab LLC | 375815-87-5361.354 | C17H19N3O6 | 96.000 | OC(C(O)C(O)=O)C(O)=O.C1[C@H]2CNC[C@@H]1c1cc3nccnc3cc21 | 5mg | 553410033
![Medchemexpress LLC 2-[(2-phenylethyl)thio]nicotinic acid | 496775-95-2 | MFCD03621206 | 99.8% | 259.33 g/mol | C14H13NO2S | 100MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000236827.png-250.jpg)
Medchemexpress LLC 2-[(2-phenylethyl)thio]nicotinic acid | 496775-95-2 | MFCD03621206 | 99.8% | 259.33 g/mol | C14H13NO2S | 100MG
ML-099 (CID-888706) is a small-molecule pan activator of Ras-related GTPases that activates Rac1, Cdc42, Ras, Rab7, and Rab-2A. Supplied as a solid research reagent with high analytical purity, it is used to probe Rho-family GTPase signaling in biochemical and cellular assays.
Medchemexpress LLC HY-W018061 5mg Medchemexpress, Traxoprodil CAS:134234-12-1 Purity:>98%
Medchemexpress, HY-W018061 5mg Traxoprodil CAS:134234-12-1 Traxoprodil (CP101,606) is a potent and selective NMDA antagonist and protect hippocampal neurons with an IC 50 of 10 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Casopitant mesylate | 414910-30-8 | 99.1% | C31H39F7N4O5S | 50 MG
Casopitant mesylate (GW679769B) is a potent, selective, brain-permeable, and orally active neurokinin 1 (NK1) receptor antagonist. It is classified as a second-in-class antiemetic that counteracts the emetogenic effect of Substance P. It is utilized for the treatment of chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV).
- Potent, selective, brain-permeable, and orally active neurokinin 1 (NK1) receptor antagonist.
- Antagonizes the emetogenic effect of Substance P.
- Substrate and a weak-to-moderate inhibitor of CYP3A4.
- Used for the treatment of chemotherapy-induced nausea and vomiting (CINV).
- Used for the treatment of postoperative nausea and vomiting (PONV).
eMolecules 3466-80-6 | 2-Phenylpiperidine | ChemScene | MFCD00270125 | 161.248 | C11H15N | 97.000 | C1CCC(NC1)c1ccccc1 | 25g | 837434310
2-Phenylpiperidine | ChemScene | 3466-80-6 | MFCD00270125 | 161.248 | C11H15N | 97.000 | C1CCC(NC1)c1ccccc1 | 25g | 837434310
Medchemexpress LLC Piperine | 94-62-2 | 98.99% | 285.34 | 100 G
Piperine is an alkaloid isolated from pepper. It can inhibit the activity of P-glycoprotein and CYP3A4, and inhibits HeLa cells with an IC50 of 61.94±0.054 μg/mL.
- Alkaloid isolated from pepper.
- Inhibits the activity of P-glycoprotein and CYP3A4.
- Inhibits HeLa cells with an IC50 of 61.94±0.054 μg/mL.
- Shown to possess in vitro cytotoxic activity.
- Immunomodulatory, anti-oxidant, anti-asthmatic, anti-carcinogenic, anti-inflammatory, anti-ulcer, and anti-amoebic properties.
- Enhances the bioavailabilities of other drugs, including rosuvastatin, puerarin, and docetaxel (DOX) by inhibiting CYP3A and P-glycoprotein activity.
- Inhibits the phosphorylation of I-κB, p65, p38, ERK, and JNK in a dose-dependent manner, suggesting potential as an anti-inflammatory drug.
Selleck Chemical LLC Y-320
Y-320 is an orally active immunomodulator and inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 of 20 to 60 nM
Medchemexpress LLC HY-101295 10mg Medchemexpress, Pan-RAS-IN-1 CAS:1835283-94-7 Purity:>98%
Medchemexpress, HY-101295 10mg Pan-RAS-IN-1 CAS:1835283-94-7 Pan-RAS-IN-1 is a pan-Ras inhibitor that disrupts the interaction of Ras proteins and their effectors. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 106-52-5 | 4-Hydroxy-1-methylpiperidine | Apollo Scientific - Building Blocks | MFCD00006500 | 115.176 | C6H13NO | 98.000 | CN1CCC(O)CC1 | 25g | 553342592
4-Hydroxy-1-methylpiperidine | Apollo Scientific - Building Blocks | 106-52-5 | MFCD00006500 | 115.176 | C6H13NO | 98.000 | CN1CCC(O)CC1 | 25g | 553342592
Medchemexpress LLC K-Ras-PDE -IN-1 100mg | 1841464-21-8 | 447.50 g·mol⁻1 | C25H26FN5O2 | 100 MG
K-Ras-PDEδ-IN-1 is a small-molecule, competitive inhibitor of PDEδ that binds the farnesyl-binding pocket with low-nanomolar affinity (Kd = 8 nM). It is supplied as a high-purity research chemical suitable for biochemical and cellular studies, with solubility and storage data provided for experimental use.
- Potent PDEδ inhibitor with a reported Kd of 8 nM.
- Binds the farnesyl-binding pocket of PDEδ.
- High purity (99.62%) suitable for research applications.
- Molecular formula C25H26FN5O2 and molecular weight 447.50 g·mol⁻1.
- Soluble in DMSO (12.5 mg/mL; sonication recommended).
- Stable as powder under low-temperature storage (powder: -20°C for 3 years; 4°C for 2 years).
- Available in a 100 MG pack size for laboratory use.