Piperidines
Selleck Chemical LLC Nelfinavir Mesylate S4282-10mM/1mL
Nelfinavir Mesylate is a potent HIV protease inhibitor with Ki of 2 nM
![Medchemexpress LLC Sulfuric acid, mono [(1R,2S,5R)-2-(aminocarbonyl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl] ester | 1192500-31-4 | 99.3% | 265.24 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC Sulfuric acid, mono [(1R,2S,5R)-2-(aminocarbonyl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl] ester | 1192500-31-4 | 99.3% | 265.24 | 1 ML
Avibactam free acid, also known as NXL-104 free acid, is a potent covalent and reversible non-β-lactam β-lactamase inhibitor. It demonstrates strong inhibitory activity against β-lactamase TEM-1 and CTX-M-15, with IC50 values of 8 nM and 5 nM, respectively. This compound exhibits minimal antibacterial activity on its own but is effective in inhibiting Class A and C β-lactamases. It does not inhibit metallo β-lactamases or Acinetobacter OXA carbapenemases.
- Broad-spectrum β-lactamase inhibition
- Synergistic activity
- In vivo efficacy
- Research applications
Medchemexpress LLC (+)-Mepivacaine | 24358-84-7 | 99.7% | 5 MG
(+)-Mepivacaine is the optically active (+)-enantiomer of the local anesthetic mepivacaine supplied as a research-grade reagent for studies of sodium channel function, membrane physiology, and neuropharmacology.
- High purity: 99.7%.
- Chemical formula: C15H22N2O.
- Molecular weight: 246.35 g/mol.
- Pack size: 5 mg.
- Recommended storage: -20°C (powder); in solvent -80°C for long-term storage.
Apexbio Technology LLC Ropivacaine hydrochloride monohydrate 132112-35-7 50mg
Ropivacaine hydrochloride monohydrate (CAS 132112-35-7) is a long-acting amide local anesthetic widely studied for its pharmacological and electrophysiological properties It inhibits ATP-sensitive potassium (KATP) channels particularly SUR2A/Kir6 2 as demonstrated in COS-7 cell models where inhibition is concentration-dependent and reversible Reported IC50 values for SUR2A/Kir6 2 SUR2B/Kir6 1 SUR2B/Kir6 2 and Kir6 2 C36 channels are 249 11 2235 115 2442 132 and 2375 179 M respectively Additionally ropivacaine hydrochloride monohydrate suppresses sarcolemmal KATP channels in cardiovascular tissues via stereoselective and tissue-specific mechanisms supporting its utility in studies of ion channel pharmacology and cardiovascular safety profiles
Apexbio Technology LLC Ropivacaine HCl 98717-15-8 10mM (in 1mL H2O)
Ropivacaine HCl (CAS 98717-15-8) is a local anesthetic agent commonly employed in biomedical research to examine neuronal function and signal transmission Mechanistically ropivacaine hydrochloride acts by reversibly blocking the influx of sodium ions across neuronal membranes thereby inhibiting the conduction of nerve impulses Due to this mode of action it serves as a useful pharmacological tool in studies designed to elucidate pain signaling pathways sodium channel behavior and peripheral nerve function
Medchemexpress LLC Mepivacaine hydrochloride | 1722-62-9 | 99.7% | 1 ML
Mepivacaine hydrochloride binds to specific voltage-gated sodium ion channels in neuronal cell membranes, inhibiting both sodium influx and membrane depolarization. This blockage of nerve impulse initiation and conduction results in a reversible loss of sensation. It has a more rapid onset and moderate duration of action compared to other local anesthetics. It also displays a preferential use-dependent block of Na(v)1.8.
- Inhibits sodium influx and membrane depolarization
- Results in reversible loss of sensation
- Rapid onset of action
- Moderate duration of action
- Displays preferential use-dependent block of Na(v)1.8
Medchemexpress LLC Ropivacaine impurity 500mg
Ropivacaine impurity 1 hydrochloride is an impurity of Ropivacaine (HY-B0563)
Medchemexpress LLC (+)-Mepivacaine | 24358-84-7 | 99.7% | 10 MG
(+)-Mepivacaine is the (+) enantiomer of mepivacaine, an amide-type local anesthetic that blocks voltage-gated sodium channels to produce temporary loss of sensation. Supplied as a high-purity research chemical for pharmacological and electrophysiological studies.
- High purity (99.7%), suitable for research applications.
- Acts as a sodium channel blocker for studies of neuronal excitability.
- Available in small milligram quantities for laboratory use (5 mg, 10 mg, 25 mg).
- Molecular formula C15H22N2O; molecular weight 246.35.
- Offered as the (+) enantiomer for enantioselective research.
Medchemexpress LLC Zidebactam | 1436861-97-0 | 100 MG
Zidebactam is a beta-lactamase inhibitor and a penicillin-binding protein 2 (PBP2) inhibitor supplied for laboratory research use. It is used to study beta-lactam resistance and to evaluate combination antibiotic therapies.
- Acts as a beta-lactamase inhibitor and PBP2 inhibitor.
- Reported PBP2 IC50 ≈ 0.26 μg/mL, suitable for potency benchmarking.
- Intended for in vitro research applications; not for human use.
- Useful for studying antibiotic resistance mechanisms and adjuvant therapies.
- Characterized by CAS 1436861-97-0 and molecular weight 391.40 g/mol.
eMolecules 127779-20-8 | Medchem Express | Saquinavir | 10mg | 446268121 | HY-17007 | MFCD00866925 | 670.855 | C38H50N6O5
Ambeed | 5-Phenylthiophen-2-amine | 250mg | 600835659 | A261937 | 14770-85-5 | MFCD11904083 | 175.250 | C10H9NS
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Cayman Chemical Levobupivacaine (hydrochloride), Purity: ≥98%, CAS: 27262-48-2, 100 mg
A sodium channel blocker and local anesthetic; levorotary stereoisomer of bupivacaine; inhibits INa by 57.8% in isolated guinea pig ventricular myocytes at 10 μM; reduces the Vmax and action potential duration to 76.7 and 83.4% of controls, respectively, in isolated guinea pig papillary muscle at 10 μM; induces a complete block of proprioception, motor function, and nociception in the hindleg of rats at 7.7 mM by percutaneous injection into the sciatic nerve
eMolecules 5382-16-1 | 4-Piperidinol | J & W PharmLab LLC | MFCD00005999 | 101.149 | C5H11NO | 96.000 | OC1CCNCC1 | 500g | 278583020
4-Piperidinol | J & W PharmLab LLC | 5382-16-1 | MFCD00005999 | 101.149 | C5H11NO | 96.000 | OC1CCNCC1 | 500g | 278583020
Accela Chembio Inc 1-benzylpiperidine-4-carboxylic Acid | 5g | 10315-07-8 | MFCD03371463 | 97+% | Shelf Life: 1980 Days | Light Sensitive
1-benzylpiperidine-4-carboxylic Acid | 5g | 10315-07-8 | MFCD03371463 | 97+% | Shelf Life: 1980 Days | Light Sensitive
Chemscene ChemScene | 1-Benzylpiperidine-4-carboxylic acid | 10G | CS-W001281 | 0.98 | 10315-07-8| MFCD03371463 | 219.28
ChemScene | 1-Benzylpiperidine-4-carboxylic acid | 10G | CS-W001281 | 0.98 | 10315-07-8| MFCD03371463 | 219.28
eMolecules 1832686-44-8 | Medchem Express | SRI 31215 (TFA) | 5mg | 455326117 | HY-114363A | 533.596 | C27H34F3N5O3
Ambeed | 4455-Tetramethyl-2-(4-methyl-2-(trifluoromethyl)phenyl)-132-dioxaborolane | 250mg | 718039640 | A1618428 | 2828445-67-4 | MFCD18729924 | 286.100 | C14H18BF3O2
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