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Filtered Search Results
Apexbio Technology LLC LDN 209929 dihydrochloride 10mg
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LDN 209929 dihydrochloride is a small-molecule inhibitor targeting haspin kinase a serine/threonine kinase It is designed to inhibit haspin kinase activity thereby regulating chromosomal alignment and mitotic progression LDN 209929 dihydrochloride exerts its biological activity primarily through selective inhibition of haspin kinase It demonstrates an IC50 of approximately 55 nM and exhibits around 180-fold selectivity over DYRK2 kinase Based on these pharmacological properties LDN 209929 dihydrochloride holds research potential in oncology studies related to aberrant mitotic control and tumor cell proliferation
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Selleck Chemical LLC PNU 282987 HCl
PNU 282987 is a potent agonist of 7-containing neuronal nicotinic acetylcholine receptors with Ki value of 26 nM for the rat receptor
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Medchemexpress LLC Tofacitinib metabolite-1 | 1640971-51-2 | MFCD32693921 | 99.6% | 328.37 g/mol | C16H20N6O2 | 5 MG
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Tofacitinib metabolite-1 is a research-grade metabolite used for pharmacokinetic and metabolism studies of tofacitinib. It is supplied as a high-purity solid suitable for in vitro and in vivo formulation development, with documented solubility and storage conditions for preclinical use.
- Metabolite of tofacitinib for pharmacokinetic and metabolism studies.
- High purity (99.6%).
- Solid, light yellow to yellow appearance.
- Soluble in DMSO (100 mg/mL); in vivo formulations ≥2.5 mg/mL with appropriate co-solvents.
- Molecular formula C16H20N6O2; molecular weight 328.37 g/mol.
- Available in small research quantities (5 mg, 10 mg; larger sizes by quote).
- Store solid at 4°C protected from light; in solution store at -80°C for long-term stability.
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Medchemexpress LLC HY-10284 100mg Medchemexpress, Linagliptin CAS:668270-12-0 Purity:>98%
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Medchemexpress, HY-10284 100mg Linagliptin CAS:668270-12-0 Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Ambeed tertButyl 4aminopiperidine1car
tert-Butyl 4-aminopiperidine-1-carboxylate, 87120-72-7, 98%
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Matrix Scientific 3-AMINOPIPERIDINE3-AMINOPIPE-1
3-aminopiperidine Mf C5h12n2 Mw 100.16 Cas 54012-73-6
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eMolecules Ambeed / 4-Piperidinopiperidine / 1g / 525114301 / A197582 / / 4897-50-1 / MFCD00006475 / 168.284 / C10H20N2
Ambeed / 4-Piperidinopiperidine / 1g / 525114301 / A197582 / / 4897-50-1 / MFCD00006475 / 168.284 / C10H20N2
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Medchemexpress LLC K-Ras ligand-Linker Conjugate 4 | 2378261-83-5 | 98.8% | 100 MG
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K-Ras ligand-Linker Conjugate 4 incorporates a ligand for a K-Ras recruiting moiety and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). It can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), a potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells.
- Incorporates a ligand for K-Ras recruiting moiety
- Features a PROTAC linker to recruit E3 ligases
- Used in the synthesis of potent PROTAC K-Ras degrader
- Degrader exhibits ≥70% degradation efficacy in SW1573 cells
- Exploits the intracellular ubiquitin-proteasome system
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Medchemexpress LLC (Rac)-LM11A-31 (dihydrochloride) | 1214672-15-7 | 99.4% | 316.27 | 10 MG
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(Rac)-LM11A-31 dihydrochloride is a significant research chemical that acts as a non-peptide modulator of the p75NTR (neurotrophin receptor p75). It is presented as an isomer and racemate of LM11A-31, demonstrating its role as an orally effective proNGF inhibitor. This compound is primarily utilized in research settings to explore pathways related to neurotrophin receptors.
- Functions as a non-peptide modulator of p75NTR
- An isomer and racemate of LM11A-31
- Acts as an orally effective proNGF inhibitor
- Primarily for research use
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Medchemexpress LLC Ras-In-2-5Mg | HY-148439-5MG
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Ras-In-2-5Mg
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Medchemexpress LLC HY-13223 10mg Medchemexpress, Crenolanib CAS:670220-88-9 Purity:>98%
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Medchemexpress, HY-13223 10mg Crenolanib CAS:670220-88-9 Crenolanib is a potent and selective inhibitor of wild-type and mutant isoforms of the class III receptor tyrosine kinases FLT3 and PDGFRα/β with Kds of 0.74 nM and 2.1 nM/3.2 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules Ambeed (R)-3-Aminopiperidin-2-one hydrochloride 250mg 570567616 A132225 0 000 406216-02-2 MFCD09752974 150 610 C5H11ClN2O
Ambeed (R)-3-Aminopiperidin-2-one hydrochloride 250mg 570567616 A132225 0 000 406216-02-2 MFCD09752974 150 610 C5H11ClN2O
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Apexbio Technology LLC UAMC 00039 dihydrochloride 697797-51-6 50mg
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UAMC 00039 dihydrochloride (CAS 697797-51-6) is a small molecule inhibitor that selectively targets dipeptidyl peptidase II It acts through a reversible and competitive mechanism exhibiting an IC50 of 0 48 nM In both in vitro and in vivo models UAMC 00039 dihydrochloride has been shown to modulate relevant signaling pathways by suppressing the enzymatic activity of its target This compound is utilized in biomedical research to investigate metabolic disorders and immune system diseases providing a tool for studying the functional role of dipeptidyl peptidase II in various physiological and pathological contexts
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eMolecules Methyl 2-(4-aminopiperidin-1-yl)nicotinate | 1185536-69-9 | MFCD15505149 | 1g
Ambeed | Methyl 2-(4-aminopiperidin-1-yl)nicotinate | 1g | 600845956 | A700891 | | 1185536-69-9 | MFCD15505149 | 235.287 | C12H17N3O2
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Medchemexpress LLC Alectinib | 1256580-46-7 | MFCD19440988 | 5mg
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Alectinib | Purity: 99.87% | MW: 482.62 | 1256580-46-7 | MFCD19440988 | 5mg
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