Pyridines and derivatives
Pyridoxal Hydrochloride 98.0+%, TCI America™
CAS: 65-22-5 Molecular Formula: C8H10ClNO3 Molecular Weight (g/mol): 203.622 MDL Number: MFCD00012809 InChI Key: FCHXJFJNDJXENQ-UHFFFAOYSA-N Synonym: pyridoxal hydrochloride,pyridoxal hcl,vitamin b6 hydrochloride,3-hydroxy-5-hydroxymethyl-2-methylisonicotinaldehyde hydrochloride,unii-1416kf0qbc,2-methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine hydrochloride,pl hcl,3-hydroxy-5-hydroxymethyl-2-methylisonicotinaldehyde, hydrochloride,3-hydroxy-5-hydroxymethyl-2-methyl-4-pyridinecarboxaldehyde hydrochloride,3-hydroxy-5-hydroxymethyl-2-methylpyridine-4-carbaldehyde hydrochloride PubChem CID: 6171 IUPAC Name: 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde;hydrochloride SMILES: CC1=NC=C(C(=C1O)C=O)CO.Cl
3,5-Lutidine 98.0+%, TCI America™
CAS: 591-22-0 Molecular Formula: C7H9N Molecular Weight (g/mol): 107.156 MDL Number: MFCD00006404 InChI Key: HWWYDZCSSYKIAD-UHFFFAOYSA-N Synonym: 3,5-lutidine,pyridine, 3,5-dimethyl,unii-6q4ypz045v,3,5-dimethyl pyridine,3,5 lutidine,3,5-lutdcine,3,5-dimethylpyridin,3,5-dimethyl-pyridine,acmc-1axev,dsstox_cid_30825 PubChem CID: 11565 IUPAC Name: 3,5-dimethylpyridine SMILES: CC1=CC(=CN=C1)C
2-Bromo-5-iodopyridine 97.0+%, TCI America™
CAS: 73290-22-9 Molecular Formula: C5H3BrIN Molecular Weight (g/mol): 283.89 MDL Number: MFCD03095201 InChI Key: LLKRSJVPTKFSLS-UHFFFAOYSA-N Synonym: 2-bromo-5-iodo-pyridine,pyridine, 2-bromo-5-iodo,5-iodo-2-bromopyridine,pubchem5969,5-iodo-2-bromo-pyridine,acmc-1bb8d,ksc493q0p,2-bromo-5-iodopyridine PubChem CID: 4738271 IUPAC Name: 2-bromo-5-iodopyridine SMILES: BrC1=CC=C(I)C=N1
2-Amino-3-methylpyridine, 97%
CAS: 1603-40-3 Molecular Formula: C6H8N2 Molecular Weight (g/mol): 108.144 MDL Number: MFCD00006320 InChI Key: RGDQRXPEZUNWHX-UHFFFAOYSA-N Synonym: 2-amino-3-picoline,2-amino-3-methylpyridine,2-pyridinamine, 3-methyl,3-methyl-2-pyridinamine,3-methyl-2-aminopyridine,3-methyl-2-pyridylamine,3-picoline, 2-amino,2-amino-3-methyl pyridine,2-amino-beta-picoline,pyridine, 2-amino-3-methyl PubChem CID: 15347 IUPAC Name: 3-methylpyridin-2-amine SMILES: CC1=C(N=CC=C1)N
5-Methyl-2-phenylpyridine 98.0+%, TCI America™
CAS: 27012-22-2 Molecular Formula: C12H11N Molecular Weight (g/mol): 169.227 MDL Number: MFCD04114180 InChI Key: ZYLPQYYLLRBVOK-UHFFFAOYSA-N Synonym: 6-Phenyl-3-picoline PubChem CID: 47467 IUPAC Name: 5-methyl-2-phenylpyridine SMILES: CC1=CN=C(C=C1)C2=CC=CC=C2
Methyl 5-Hydroxynicotinate 98.0+%, TCI America™
CAS: 30766-22-4 Molecular Formula: C7H7NO3 Molecular Weight (g/mol): 153.14 MDL Number: MFCD00191521 InChI Key: KJJSHOHQQHACLE-UHFFFAOYSA-N Synonym: methyl 5-hydroxynicotinate,5-hydroxynicotinic acid methyl ester,methyl5-hydroxynicotinate,methyl 5-hydroxy-3-pyridinecarboxylate,5-hydroxy-nicotinic acid methyl ester,methyl-5-hydroxynicotinate,5-hydroxy-3-pyridinecarboxylic acid methyl ester,3-pyridinecarboxylic acid, 5-hydroxy-, methyl ester,5-hydroxy nicotinic acid methyl ester,acmc-1crme PubChem CID: 354317 IUPAC Name: methyl 5-hydroxypyridine-3-carboxylate SMILES: COC(=O)C1=CC(O)=CN=C1
Propyl 3-Propoxypyridine-2-carboxylate 98.0+%, TCI America™
CAS: 134319-22-5 Molecular Formula: C12H17NO3 Molecular Weight (g/mol): 223.272 MDL Number: MFCD00191575 InChI Key: ZGUCGLNLZXLQTD-UHFFFAOYSA-N Synonym: 3-Propoxypicolinic Acid Propyl Ester, Propyl 3-Propoxypicolinate, 3-Propoxypyridine-2-carboxylic Acid Propyl Ester PubChem CID: 19756120 IUPAC Name: propyl 3-propoxypyridine-2-carboxylate SMILES: CCCOC1=C(N=CC=C1)C(=O)OCCC
Medchemexpress LLC Voacangine | 510-22-5 | 5 MG
Voacangine is an alkaloid isolated from the root bark of *Voacanga africana*. It acts as an antagonist for TRPV1 and TRPM8, and an agonist for TRPA1. It competitively blocks capsaicin binding to TRPV1 and inhibits menthol binding to TRPM8. Voacangine selectively abrogates chemical agonist-induced TRPM8 activation without affecting cold-induced activation.
- Acts as an antagonist for TRPV1 and TRPM8
- Functions as an agonist for TRPA1
- Competitively blocks capsaicin binding to TRPV1
- Inhibits menthol binding to TRPM8
- Suppresses in vitro angiogenesis
Apexbio Technology LLC Riluzole 1744-22-5 500mg
Riluzole (CAS 1744-22-5) is a small molecule modulator of glutamatergic neurotransmission exhibiting multiple mechanisms of neuroprotection Its action primarily involves inhibition of voltage-gated sodium channels modulation of high-voltage-activated calcium and potassium channels and interference with protein kinase C activity collectively mitigating neuronal excitotoxicity In cultured rat cortical neurons riluzole inhibits inward sodium currents with an IC50 of 51 M At submicromolar to micromolar concentrations riluzole enhances sodium-dependent glutamate uptake mediated by the GLAST GLT1 and EAAC1 transporters Owing to these properties riluzole is commonly utilized in neuroscience research on excitotoxicity neurodegeneration and related pathologies
Medchemexpress LLC Voacangine | 510-22-5 | 1 MG
Voacangine is an antagonist for TRPV1 and TRPM8, and an agonist for TRPA1 (EC50=8 μM). It competitively blocks capsaicin binding to TRPV1 (IC50=50 μM) and inhibits menthol binding to TRPM8 (IC50=9 μM). It is isolated from the root bark of Voacanga africana.
- Antagonist for TRPV1 and TRPM8.
- Agonist for TRPA1 (EC50=8 μM).
- Competitively blocks capsaicin binding to TRPV1 (IC50=50 μM).
- Competitively inhibits the binding of menthol to TRPM8 (IC50=9 μM).
- Shows noncompetitive inhibition against icilin (IC50=7 μM).
- Selectively abrogates chemical agonist-induced TRPM8 activation.
- Does not affect cold-induced TRPM8 activation.
- Alkaloid isolated from the root bark of Voacanga africana.
- Purity: 98.78%.
- Appearance: Solid, white to off-white.
Medchemexpress LLC Riluzole | 1744-22-5 | 50 MG
Riluzole is an anticonvulsant agent that functions as a use-dependent Na+ channel blocker. It also demonstrates the ability to inhibit GABA uptake, with an IC50 of 43 μM.
- Acts as an anticonvulsant agent.
- Functions as a use-dependent Na+ channel blocker.
- Inhibits GABA uptake.
- Inhibits peak autaptic IPSCs slightly at 20 μM, while reliably prolonging them.
- Enhances responses to 2 μM GABA in a strong, concentration-dependent, and readily reversible manner.
- Exhibits an EC50 of approximately 60 μM for the potentiation of GABA responses.
Medchemexpress LLC Ceftezole sodium | 41136-22-5 | 5 MG
Ceftezole sodium is a broad-spectrum cephem antibiotic effective against many gram-positive and gram-negative bacteria. It also acts as an alpha-glucosidase inhibitor with in vivo anti-diabetic activity.
- Broad-spectrum cephem antibiotic
- Effective against many gram-positive and gram-negative bacteria
- Alpha-glucosidase inhibitor
- In vivo anti-diabetic activity
Medchemexpress LLC Sorbifolin | 23130-22-5 | 300.26 | 5 MG
Sorbifolin, a flavone glucoside, can be isolated from the Pterogyne nitens. Sorbifolin has myeloperoxidase inhibitory and radical scavenging activities. Sorbifolin is also a MPO inhibitor with an IC50 value of 19.2 nM.
- Flavone glucoside
- Can be isolated from Pterogyne nitens
- Myeloperoxidase inhibitory activity
- Radical scavenging activities
- MPO inhibitor with an IC50 value of 19.2 nM
Medchemexpress LLC Mometasone | 105102-22-5 | 99.5% | 5 MG
Mometasone is an inhaled glucocorticoid that can be used for mild asthma with a low sputum eosinophil level. It also shows potential for research in chronic hand eczema and rhinosinusitis.
- Inhaled glucocorticoid
- Can be used for mild asthma with a low sputum eosinophil level
- Potential for research in chronic hand eczema
- Potential for research in rhinosinusitis
- Appearance: White to off-white solid
- Purity: 99.46%
- Target: Glucocorticoid receptor
- Pathway: Immunology/inflammation; Vitamin D related/nuclear receptor
Apexbio Technology LLC Calcipotriol monohydrate 147657-22-5 50mg
Calcipotriol monohydrate (CAS 147657-22-5) is a synthetic analog of vitamin D3 designed to modulate keratinocyte activity It acts by binding to the vitamin D receptor leading to inhibition of keratinocyte proliferation and induction of their physiological differentiation These effects collectively reduce abnormal epidermal growth and the formation of scaling plaques Calcipotriol monohydrate is widely utilized in biomedical research to investigate the regulation of epidermal differentiation vitamin D receptor-mediated signaling and the pathophysiology of disorders such as psoriasis