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Filtered Search Results
Medchemexpress LLC Ethyl Caffeate | 102-37-4 | MFCD00045754 | 1 ML
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Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. It suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin. It is for research use only.
- Isolated from Bidens pilosa
- Suppresses NF-κB activation
- Inhibits iNOS, COX-2, and PGE2
- For research use only
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Medchemexpress LLC N-Caffeoyl O-methyltyramine | 189307-47-9 | 1 ML
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N-Caffeoyl O-methyltyramine is an alkaloid isolated from Cuscuta reflexa that demonstrates strong inhibitory activity against α-glucosidase. It has a molecular weight of 313.35 and a chemical formula of C18H19NO4. This product is supplied as a 10 mM solution in 1 mL for research use only.
- Strong inhibitory activity against α-glucosidase
- Molecular weight of 313.35
- Chemical formula C18H19NO4
- Isolated from Cuscuta reflexa
- For research use only
- Supplied as a 10 mM solution in 1 mL
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Medchemexpress LLC 6-Maleimidocaproic acid-PFP ester | 692739-25-6 | C16H12F5NO4 | 250 MG
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6-Maleimidocaproic acid-PFP ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Alkyl chain-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC 6-Oxohexyl 2-hexyldecanoate | 1849616-54-1 | 80.0% | C22H42O3 | 250 MG
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6-Oxohexyl 2-hexyldecanoate, 80% (ELSD) is an intermediate used in the synthesis of ALC-0315. It can be utilized in research related to drug delivery, including mRNA delivery. ALC-0315 is an ionizable amino lipid and a key component of LNP delivery vehicles.
- Intermediate in the synthesis of ALC-0315
- Suitable for research on drug delivery
- Supports mRNA delivery studies
- Contributes to LNP delivery vehicles
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Medchemexpress LLC Trpc5-in-1 | 2265215-18-5 | 99.0% | C20H16N4O | 250 MG
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TRPC5-IN-1 (Compound 6j) is a selective TRPC5 inhibitor. This solid, white to off-white compound demonstrates 50.5% inhibition for TRPC5 at 3 μM and is suitable for research related to chronic kidney disease (CKD). It is intended for research use only.
- Selective TRPC5 inhibitor
- Suitable for chronic kidney disease (CKD) research
- Solid, white to off-white appearance
- 50.5% inhibition for TRPC5 at 3 μM
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Medchemexpress LLC Bromoacetamido-C2-PEG2-NH-Boc | 182244-33-3 | C13H25BrN2O5 | 250 MG
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Bromoacetamido-C2-PEG2-NH-Boc is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. The appearance of the product is a solid with a white to off-white color.
- Utilized in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Solid appearance
- White to off-white color
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Medchemexpress LLC Phenol, 4-(6-methyl-1,2,4,5-tetrazin-3-yl)- | 58884-35-8 | 97.53% | C9H8N4O | 250 MG
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4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol is an alkyl chain-based PROTAC linker designed for the synthesis of PROTACs. These Proteolysis Targeting Chimeras consist of two different ligands connected by a linker, targeting an E3 ubiquitin ligase and a specific target protein. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only.
- Appearance: Pink to red solid
- Solubility in DMSO: 100 mg/mL
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In-solvent storage: -80°C for 6 months, -20°C for 1 month
- Related classification: Click Chemistry (Tetrazine)
- Relevant disease areas: Cancer, Cancer Targeted Therapy
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Medchemexpress LLC m-PEG-mal (MW 30000) | 98.0% | 250 MG
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m-PEG-mal (MW 30000) is a PEG-based PROTAC linker used in the synthesis of PROTACs. This product is intended for research use only in laboratory settings. PROTACs are designed to utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- For synthesis of PROTACs
- Utilizes ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
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Medchemexpress LLC 2'-O-Methyl-8-methyl guanosine | 2306782-64-7 | 98.0% | C12H17N5O5 | 25 MG
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2'-O-Methyl-8-methyl guanosine (m8Gm) is a Z-form RNA stabilizer. It can stabilize Z-RNA at low salt conditions, and m8Gm-contained oligonucleotides can stabilize Z-DNA under low salt conditions.
- Stabilizes Z-RNA at low salt conditions
- Oligonucleotides containing m8Gm can stabilize Z-DNA under low salt conditions
- Molecular weight of 311.29
- Appears as a white to off-white solid
- Soluble in DMSO at 100 mg/mL
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Medchemexpress LLC Butanoic acid, 2-ethyl-2-hydroxy- | 3639-21-2 | 98.0% | C6H12O3 | 1 G
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2-Ethyl-2-hydroxybutanoic acid, also known as 2-Ethyl-2-hydroxybutyric acid, is a hydroxy fatty acid. It is identified as a metabolite of DEHP and is provided as a white to off-white solid.
- Hydroxy fatty acid
- Metabolite of DEHP
- High purity (98.0%)
- Consistent with structure
- Suitable for research use only
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
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Medchemexpress LLC Histamine H4 receptor antagonist-1 | 1246207-84-0 | 99.57% | C30H38N8O2 | 25 MG
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Histamine H4 receptor antagonist-1 is an antagonist of the histamine H4 receptor, extracted from patent WO2010108059A1 compound 60. It is intended for research use only.
- Purity of 99.57%
- Targets histamine H4 receptor
- Molecular weight of 542.68
- Appears as an off-white to light brown solid
- Store powder at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 6 months or -20°C for 1 month
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Medchemexpress LLC Methyl cellulose | 9004-67-5 | MFCD00081763 | >95.0% | 454.51 g/mol | C20H38O11 | 25G
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Methyl cellulose is a non-ionic cellulose ether supplied as a low-viscosity reagent (15 mPa·s) used to modify rheology and stabilize formulations. It is water soluble, thermogelating, and commonly applied as a thickener, stabilizer, emulsifier, and excipient in pharmaceutical, food, cosmetic, and construction applications. Typical small-pack sizes support laboratory and formulation development work.
- Low viscosity grade (15 mPa·s) suitable for easy dispersion
- Water soluble and forms a gel on heating
- Functions as a thickener, stabilizer, and emulsifier
- Useful as an excipient in drug delivery and formulation testing
- Available in small pack sizes for research and development
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC 5'-O-DMT-N2-Ibu-2'-OMe-G | 251647-50-4 | MFCD03428520 | 98.0% | 713.78 g/mol | C38H43N5O9 | 1 G
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5'-O-DMT-N2-Ibu-2'-OMe-G is a protected guanosine derivative used as an intermediate in the synthesis of antisense oligonucleotides and related nucleic acid chemistries. It is supplied for research use and characterized for synthetic applications.
- Protected guanosine derivative for oligonucleotide synthesis.
- Reported purity 98.0%.
- Molecular weight 713.78 g/mol.
- Molecular formula C38H43N5O9.
- Available in laboratory-scale package sizes, including 1 G.
- Intended as a drug intermediate and reference compound for synthesis.
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Medchemexpress LLC TCS7010 | 1158838-45-9 | 99.8% | C31H31ClFN7O2 | 250 MG
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TCS7010 is a potent and highly selective Aurora A inhibitor with an IC50 of 3.4 nM. It is considered a useful tool for investigating the cellular role of Aurora A kinases without the complication of also inhibiting Aurora B.
- Potent and highly selective Aurora A inhibitor
- IC50 of 3.4 nM for Aurora A
- Useful tool for investigating cellular role of Aurora A kinases
- Does not inhibit Aurora B at relevant concentrations
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![eMolecules Ambeed / 6-Nitrobenzo[b]thiophene 11-dioxide / 1mg / 717400917 / A109795 / / 19983-44-9 / MFCD00173799 / 211.190 / C8H5NO4S](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502427804.JPG-250.jpg)
eMolecules Ambeed / 6-Nitrobenzo[b]thiophene 11-dioxide / 1mg / 717400917 / A109795 / / 19983-44-9 / MFCD00173799 / 211.190 / C8H5NO4S
Ambeed / 6-Nitrobenzo[b]thiophene 11-dioxide / 1mg / 717400917 / A109795 / / 19983-44-9 / MFCD00173799 / 211.190 / C8H5NO4S
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