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Filtered Search Results
Medchemexpress LLC Org41841 | 301847-37-0 | 99.8% | 402.53 g/mol | C19H22N4O2S2 | 25 MG
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Org41841 is a small-molecule partial agonist of the luteinizing hormone/chorionic gonadotropin receptor (LHCGR) and the thyroid-stimulating hormone receptor (TSHR), used for receptor pharmacology research. It exhibits EC50 values of 0.2 μM (LHCGR) and 7.7 μM (TSHR).
- Partial agonist at LHCGR and TSHR with EC50s of 0.2 μM and 7.7 μM.
- High purity (99.77%) appropriate for biochemical assays.
- Molecular weight 402.53 g/mol.
- Chemical formula C19H22N4O2S2.
- CAS number 301847-37-0 for unambiguous identification.
- Available in multiple milligram quantities and DMSO solution formats for screening.
- Intended for research use only and not for human or clinical use.
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Aobchem 5-(4-Methylphenyl)-2-pyrimidinamine | ≥97% | CAS 31408-17-0 | C11H11N3 | 500mg
5-(4-Methylphenyl)-2-pyrimidinamine | ≥97% | CAS 31408-17-0 | C11H11N3 | 500mg
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Aobchem 5-(4-Methylphenyl)-2-pyrimidinamine | ≥97% | CAS 31408-17-0 | C11H11N3 | 1g
5-(4-Methylphenyl)-2-pyrimidinamine | ≥97% | CAS 31408-17-0 | C11H11N3 | 1g
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Aobchem 5-(4-Methylphenyl)-2-pyrimidinamine | ≥97% | CAS 31408-17-0 | C11H11N3 | 5g
5-(4-Methylphenyl)-2-pyrimidinamine | ≥97% | CAS 31408-17-0 | C11H11N3 | 5g
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000308399 PKI-166 5MG
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eMolecules 75894-93-8 | 2-(3,5-Dibromophenyl)ethanol | Oakwood Chemical | MFCD11617976 | 279.959 | C8H8Br2O | 95.000 | OCCc1cc(Br)cc(Br)c1 | 1g | 537711235
2-(3,5-Dibromophenyl)ethanol | Oakwood Chemical | 75894-93-8 | MFCD11617976 | 279.959 | C8H8Br2O | 95.000 | OCCc1cc(Br)cc(Br)c1 | 1g | 537711235
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Medchemexpress LLC PKI(5-24) | 99534-03-9 | 99.99% | 2222.38 | 10 MG
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PKI(5-24) is a potent, competitive, and synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase), with a Ki of 2.3 nM. It corresponds to residues 5-24 in the naturally occurring heat-stable protein kinase inhibitor. This 20-residue peptide inhibits phosphotransferase activity of the mutant cGMP kinase with higher potency (Ki of 42 μM) than that of the wild type (Ki of 160 μM). This product is for research use only.
- Potent, competitive, and synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase)
- Ki of 2.3 nM
- Corresponds to residues 5-24 in the naturally occurring heat-stable protein kinase inhibitor
- 20-residue peptide synthesized to correspond to the active site of the skeletal muscle inhibitor protein
- Inhibits phosphotransferase activity of the mutant cGMP kinase with higher potency
- For research use only
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Medchemexpress LLC HY-10115A 100mg , PI-103 (Hydrochloride) CAS:371935-79-4 Purity:98%
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Medchemexpress, HY-10115A 100mg PI-103 (Hydrochloride) CAS:371935-79-4 Formula:C19H17ClN4O3 IC50: 8 nM (p110α), 88 nM (p110β), 48 nM (p110δ), 150 nM (p110γ), 2 nM (DNA-PK), 20 nM (mTORC1), 83 nM (mTORC2), 26 nM (PI3KC2β), 850 nM (ATR), 920 nM (ATM), ~1 μM (PI3KC2α), 2.3 μM (hsVPS34), ~50 μM (PI4KIIIβ) Purity:98% PI-103 Hydrochloride is a potent PI3K and mTOR inhibitor with IC 50 s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α , p110β , p110δ , p110γ , mTORC1 , and mTORC2 . PI-103 also inhibits DNA-PK with an IC50 of 2 nM. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Derenofylline | 251945-92-3 | 99.9% | 308.38 | 50 MG
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Derenofylline (SLV 320) is a potent, selective, and orally active adenosine A1 receptor antagonist. It exhibits Ki values of 1 nM for human A1, 200 nM for A3, and 398 nM for A2A receptors. This compound suppresses cardiac fibrosis and attenuates albuminuria without affecting blood pressure in rats. It has also shown to inhibit TGF-β1-induced myofibroblast transformation in vitro and reduce myocardial fibrosis in vivo.
- Potent, selective, and orally active adenosine A1 receptor antagonist
- Suppresses cardiac fibrosis
- Attenuates albuminuria
- Inhibits TGF-β1-induced myofibroblast transformation (in vitro)
- Reduces myocardial fibrosis in 5/6 nephrectomy rats (in vivo)
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Medchemexpress LLC Phenyl 6-(3-methoxy-2-(4-(trifluoromethyl)phenyl)benzoylamino)-3,4-dihydroisoquinoline-2-carboxylate | 913541-47-6 | MFCD28502203 | 99.0% | 546.54 | C31H25F3N2O4 | 50 MG
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SLX-4090 is an orally active, enterocytic-specific microsomal triglyceride transfer protein (MTP) inhibitor (IC50 8.0 nM) used as a research reagent in dyslipidemia and lipid metabolism studies. It is supplied as a purified solid and is available in solution formats suitable for in vitro and in vivo assays.
- High potency MTP inhibition (IC50 ~8.0 nM).
- Enterocytic-specific activity useful for targeted lipid studies.
- High purity (about 98.97%) for reproducible results.
- Available as solid and DMSO solution formats for assay flexibility.
- Suitable for dyslipidemia and lipid metabolism research models.
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eMolecules 854890-84-9 | 1-(2,5-Dibromophenyl)thiourea | Combi-Blocks | MFCD14673413 | 310.010 | C7H6Br2N2S | 98.000 | NC(=S)Nc1cc(Br)ccc1Br | 1g | 117531798
1-(2,5-Dibromophenyl)thiourea | Combi-Blocks | 854890-84-9 | MFCD14673413 | 310.010 | C7H6Br2N2S | 98.000 | NC(=S)Nc1cc(Br)ccc1Br | 1g | 117531798
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eMolecules 50739-76-9 | (2-Amino-3,5-dibromophenyl)methanol | Combi-Blocks | MFCD06202693 | 280.947 | C7H7Br2NO | 95.000 | Nc1c(Br)cc(Br)cc1CO | 1g | 439374801
(2-Amino-3,5-dibromophenyl)methanol | Combi-Blocks | 50739-76-9 | MFCD06202693 | 280.947 | C7H7Br2NO | 95.000 | Nc1c(Br)cc(Br)cc1CO | 1g | 439374801
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Medchemexpress LLC Phenyl 6-[[3-methoxy-2-[4-(CF3)phenyl]benzoyl]amino]-3,4-dihydro-1H-isoquinoline-2-carboxylate | 913541-47-6 | MFCD28502203 | ≥98.0% | 546.5 g·mol⁻¹ | C31H25F3N2O4 | 100 MG
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SLX-4090 is a small-molecule, orally active, enterocytic-specific microsomal triglyceride transfer protein (MTP) inhibitor with a reported IC50 of ~8.0 nM. It is used in preclinical research to investigate intestinal lipid absorption and dyslipidemia and is characterized in peer-reviewed literature.
- Potent MTP inhibition with low-nanomolar IC50.
- Enterocyte-selective activity targeting intestinal lipid handling.
- Suitable for preclinical and mechanistic studies of dyslipidemia.
- High chemical purity for reproducible experimental results.
- Available as solid and solution formulations for flexibility in assays.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000771222 5-PYRIMIDIN-5-YLIS 250MG
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Ambeed AMBEED
5000891095 N-METHYL-1-PYRIMIDIN-2-Y 100MG
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