Pyrroles
![eMolecules 625-82-1 | 2,4-Dimethyl-1H-pyrrole | Ambeed | MFCD00192088 | 95.145 | C6H9N | 98.000 | Cc1c[nH]c(C)c1 | 10g | 525246779](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000474156.jpg-250.jpg)
eMolecules 625-82-1 | 2,4-Dimethyl-1H-pyrrole | Ambeed | MFCD00192088 | 95.145 | C6H9N | 98.000 | Cc1c[nH]c(C)c1 | 10g | 525246779
2,4-Dimethyl-1H-pyrrole | Ambeed | 625-82-1 | MFCD00192088 | 95.145 | C6H9N | 98.000 | Cc1c[nH]c(C)c1 | 10g | 525246779
![eMolecules 625-82-1 | 2,4-Dimethyl-1H-pyrrole | Ambeed | MFCD00192088 | 95.145 | C6H9N | 98.000 | Cc1c[nH]c(C)c1 | 100g | 525246780](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
eMolecules 625-82-1 | 2,4-Dimethyl-1H-pyrrole | Ambeed | MFCD00192088 | 95.145 | C6H9N | 98.000 | Cc1c[nH]c(C)c1 | 100g | 525246780
2,4-Dimethyl-1H-pyrrole | Ambeed | 625-82-1 | MFCD00192088 | 95.145 | C6H9N | 98.000 | Cc1c[nH]c(C)c1 | 100g | 525246780
![eMolecules 625-82-1 | 2,4-Dimethyl-1H-pyrrole | Apollo Scientific | MFCD00192088 | 95.145 | C6H9N | 98.000 | Cc1c[nH]c(C)c1 | 5g | 562530882](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000491286.jpg-250.jpg)
eMolecules 625-82-1 | 2,4-Dimethyl-1H-pyrrole | Apollo Scientific | MFCD00192088 | 95.145 | C6H9N | 98.000 | Cc1c[nH]c(C)c1 | 5g | 562530882
2,4-Dimethyl-1H-pyrrole | Apollo Scientific | 625-82-1 | MFCD00192088 | 95.145 | C6H9N | 98.000 | Cc1c[nH]c(C)c1 | 5g | 562530882
Medchemexpress LLC MDL-29951 | 130798-51-5 | 99.2% | 302.11 | 5 MG
MDL-29951 is a novel glycine antagonist of NMDA receptor activation, exhibiting a Ki of 0.14 μM for [3H]glycine binding both in vitro and in vivo. It is intended for research use only.
- Approximately 2000-fold selective for the glycine binding site over glutamate recognition sites.
- Inhibits human F16Bpase (IC50=2.5 μM), porcine kidney (IC50=1.0 μM), and rabbit liver (IC50=0.21 μM) isoforms of the enzyme.
- Promotes Ca2+ signaling responses and inhibits cyclic adenosine monophosphate (cAMP) accumulation in rat oligodendrocyte precursor cells.
- Exhibits GPCR-mediated signaling activities, including G protein-dependent activation of ERK1/2 and recruitment of β-arrestin.
Medchemexpress LLC Pyrrole-2-carboxylic acid | 634-97-9 | 111.10 | 50 G
Pyrrole-2-carboxylic acid is a natural alkaloid found in the marine bacterium *Pelomonas puraquae* sp. Nov. It is a biological form of pyrrole often present in natural compounds and serves as a precursor for various pyrrole derivatives such as clorobiocin, coumermycin A1, pyoluteorin, leupyrrins, and undecylprodigiosin in biosynthetic processes. This product is for research use only.
- Natural alkaloid found in marine bacterium *Pelomonas puraquae* sp. Nov.
- Biological form of pyrrole.
- Precursor for various pyrrole derivatives (clorobiocin, coumermycin A1, pyoluteorin, leupyrrins, undecylprodigiosin).
- For research use only.
Apexbio Technology LLC Pyrrole-2-carboxylic acid 634-97-9 500mg
Pyrrole-2-carboxylic acid (CAS 634-97-9) is a heterocyclic organic compound characterized by a carboxyl substituent at the 2-position of the pyrrole ring This molecule has been investigated in biomedical research as an inhibitor of certain enzymatic pathways involving pyrrole derivatives including roles in microbial metabolism and secondary metabolite biosynthesis Pyrrole-2-carboxylic acid is utilized in studies examining enzyme specificity metabolic pathway modulation and as a precursor in the synthesis of pharmacologically relevant molecules Its defined structure makes it a valuable tool for probing pyrrole-related biochemical mechanisms
Medchemexpress LLC KH-CB20 | 1354448-60-4 | MFCD00407230 | 99.8% | 338.19 g/mol | C15H13Cl2N3O2 | 5 MG
KH-CB20 is a research-grade small-molecule inhibitor of CDC-like kinases (CLK1 and CLK4). Supplied as an E/Z isomer mixture, it exhibits potent biochemical activity and is provided as a high-purity solid for biochemical and cell-based assays related to splicing and cell-cycle regulation. Refer to the supplier datasheet for experimental and safety information.
- Potent inhibition of CLK1 and CLK4 (CLK1 IC50 16.5 nM).
- Also active against DYRK1A and CLK3.
- High-purity solid suitable for analytical and preparative work.
- Available in milligram quantities and as a DMSO solution.
- Intended for research use only; follow safety and handling guidance.
Medchemexpress LLC TAK-285 | 871026-44-7 | C26H25ClF3N5O3 | 100 MG
TAK-285 is a potent, selective, ATP-competitive, and orally active HER2 and EGFR (HER1) inhibitor. It demonstrates effective antitumor activity and can cross the blood-brain barrier (BBB). This compound exhibits significant growth inhibitory activity against BT-474 cells.
- Potent and selective HER2 and EGFR (HER1) inhibitor
- IC50 values of 17 nM for HER2 and 23 nM for EGFR (HER1)
- Shows over 10-fold selectivity for HER1/2 compared to HER4
- Less potent against MEK1/5, c-Met, Aurora B, Lck, and CSK
- Demonstrates effective antitumor activity
- Can cross the blood-brain barrier (BBB)
- Exhibits significant growth inhibitory activity against BT-474 cells with a GI50 of 17 nM
- Inhibits MEK1, MEK5, c-Met, Aurora B, Lck, CSK, and Lyn B with varying IC50s
Enzo Life Sciences Z-AAF-CMK (5mg)
Negative control for serine protease inhibitor AAF-CMK which inhibits tripeptidyl peptidase II (TPPII), a giant protease which may substitute for some proteasome functions. Blockage of the N-terminus by the Benzyloxycarbonyl or “Z” group abolishes the activity of the AAF-CMK inhibitor. Alternative name: Z-Ala-Ala-Phe-CMK. Purity: ≥98% (TLC). Solubility: Soluble in DMSO(2 mg/ml) or ethanol (2 mg/ml). Long Term Storage: -20°C.
eMolecules 292168-79-7 | Medchem Express | KY1220 | 2mg | 446257598 | HY-102028 | 314.32 | C14H10N4O3S
ChemScene | 27-Dibromo-9-octyl-9H-carbazole | 250mg | 714104124 | CS-0152157 | 726169-75-1 | MFCD19440901 | 437.219 | C20H23Br2N
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Selleck Chemical LLC Quisinostat (JNJ-26481585) 2HCl S1096-5mg
Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0 11 nM in a cell-free assay modest potent to HDACs 2 4 10 and 11 greater than 30-fold selectivity against HDACs 3 5 8 and 9 and lowest potency to HDACs 6 and 7 Phase 2
Medchemexpress LLC HY-100471 1mg Medchemexpress, Esaxerenone CAS:1632006-28-0 Purity:>98%
Medchemexpress, HY-100471 1mg Esaxerenone CAS:1632006-28-0 Esaxerenone is a novel, highly potent and selective non-steroidal mineralocorticoid receptor antagonist. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Ac-YVAD-cmk | 178603-78-6 | MFCD00237124 | 98.9% | 540.99 g/mol | C24H33ClN4O8 | 10 MG
Ac-YVAD-cmk is a peptide-based, irreversible inhibitor of caspase-1 (interleukin-1β converting enzyme) used in biochemical and cell-based research to block caspase-1 activity and reduce maturation of proinflammatory cytokines. It is commonly applied in studies of inflammation, pyroptosis, and neuroprotection.
- Selective inhibition of caspase-1 activity in biochemical assays and cell models.
- Irreversible peptide-based inhibitor for sustained target engagement.
- Reduces processing of IL-1β and IL-18 in inflammasome-related research.
- High supplied purity suitable for research applications.
- Available in multiple pack sizes and as a ready-to-use DMSO solution.
- Accompanied by datasheet, SDS, and certificate of analysis for reproducible experiments.
Biotang Inc Tubastatin A, Hydrochloride Salt, > 99%, 10MG, M.W. 371.86. C20H21N3O2HCl. CAS#1310693-92-5
Tubastatin A, Hydrochloride Salt, > 99%, 10MG, M.W. 371.86. C20H21N3O2HCl. CAS#1310693-92-5
eMolecules 1346574-57-9 | Medchem Express | GSK126 | 5mg | 446262974 | HY-13470 | MFCD23381067 | 526.685 | C31H38N6O2
Medchem Express | ISR-IN-2 | 5mg | 784544231 | HY-153075 | 1628478-12-5 | 520.230 | C22H22Cl4N2O4
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