Pyrroles
Medchemexpress LLC Varespladib methyl | 172733-08-3 | 99.9% | 394.42 | 50 MG
Varespladib methyl is a selective inhibitor of group II secretory phospholipase A2 (PLA2). It is an orally-administered methyl ester pro-drug that is metabolized to LY315920. It demonstrates high-level secretory PLA2 (sPLA2) inhibition at nanomolar and picomolar concentrations against 28 medically important snake venoms.
- Selective inhibitor of group II secretory phospholipase A2 (PLA2)
- Orally-administered methyl ester pro-drug
- Metabolized to LY315920
- Shows high-level sPLA2 inhibition against snake venoms
Medchemexpress LLC HY-18901 5mg Medchemexpress, RIPK1-IN-4 CAS:1481641-08-0 Purity:>98%
Medchemexpress, HY-18901 5mg RIPK1-IN-4 CAS:1481641-08-0 RIPK1-IN-4 (compound 8) is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase and binds to a DLG-out inactive form of RIP1 with an IC50s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Midostaurin | 120685-11-2 | MFCD00871372 | 5 mg
Midostaurin | Purity: 99.89% | Mol Wt: 570.65 | 120685-11-2 | MFCD00871372 | 5 mg
Medchemexpress LLC Ripk1-in-4 | 1481641-08-0 | 98.89% | 401.46 | 100 MG
RIPK1-IN-4 (compound 8) is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase. It binds to a DLG-out inactive form of RIP1 with IC50s of 16 nM for RIP1 and 10 nM for ADP-Glo kinase. This compound is intended for research use only.
- Potent and selective type II kinase inhibitor
- Targets receptor interacting protein 1 (RIP1) kinase
- Binds to a DLG-out inactive form of RIP1
- Inhibits autophosphorylation of RIP1 kinase domain with an IC50 of 0.01 μM
- Prevents TNFalpha/zVAD.fmk-induced necrotic cell death
eMolecules 173326-37-9 | Medchem Express | BQ-788 | 1mg | 415687676 | HY-15894A | MFCD06245594 | 641.81 | C34H51N5O7
Medchem Express | A-205804 | 10mg | 518570842 | HY-100226 | 251992-66-2 | MFCD09038566 | 300.390 | C15H12N2OS2
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Medchemexpress LLC Ac-FEID-CMK TFA | 97.06% | 711.08 | 10 MG
Ac-FEID-CMK TFA is a potent zebrafish-specific GSDMEb-derived peptide inhibitor. It can attenuate the mortality and kidney injury during septic shock and inhibit pyroptosis and attenuate septic AKI (acute kidney injury) in vivo. It can also suppress the caspy2-mediated noncanonical inflammasome pathway.
- Potent zebrafish-specific GSDMEb-derived peptide inhibitor
- Attenuates mortality and kidney injury during septic shock
- Inhibits pyroptosis
- Attenuates septic AKI (acute kidney injury) in vivo
- Suppresses caspy2-mediated noncanonical inflammasome pathway
eMolecules 1793053-37-8 | Medchem Express | LLY-507 | 5mg | 446269670 | HY-19313 | MFCD28902312 | 574.773 | C36H42N6O
Ambeed | Methyl 12-bromododecanoate | 1g | 524988976 | A103359 | 26825-95-6 | MFCD01838179 | 293.245 | C13H25BrO2
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